Industry ChallengesIssues in the synthetic lethality space, particularly for companies like Repare and Zentalis, cast a shadow over Aprea.
Market HeadwindsAprea, like many small biotechs, has been pressured by broad market headwinds and a lack of significant catalysts.
Market-Driven Share Price DeclineAprea's share price has pulled back to near an all-time low, driven by factors unrelated to the synthetic lethality pipeline.