Analyst DowngradeAnalyst downgrades VYNE from Buy to NEUTRAL as they await additional updates from management.
High Discontinuation RatesThe overall discontinuation rates were high, with 30.7% of repibresib-treated patients discontinuing treatment before 24 weeks, which was higher than those seen in other approved or late-stage therapies.
Trial DiscontinuationThe Phase IIb study evaluating repibresib gel in nonsegmental vitiligo did not meet its primary or key secondary endpoint, leading to the termination of the extension phase of the trial.