Vyne Therapeutics Inc ( (VYNE) ) has released its Q3 earnings. Here is a breakdown of the information Vyne Therapeutics Inc presented to its investors.
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VYNE Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for inflammatory and immune-mediated conditions, utilizing its proprietary BET inhibitors to address unmet medical needs.
In its latest earnings report for the third quarter of 2025, VYNE Therapeutics announced its ongoing strategic review aimed at maximizing shareholder value, alongside updates on its pipeline developments and financial performance. The company is actively exploring strategic alternatives, including partnerships and potential transactions, while progressing with its VYN202 toxicology study in dogs.
Key financial highlights include a decrease in research and development expenses by 48.7% compared to the previous year, attributed to reduced spending on its repibresib and VYN202 programs. The company reported a net loss of $7.3 million for the quarter, an improvement from the $12.2 million loss in the same period last year. VYNE’s cash position remains strong, with a runway extending into the first half of 2027.
Strategically, VYNE is focused on resolving the clinical hold on VYN202 for male subjects and is seeking a development partner for its repibresib gel program following mixed results in its Phase 2b trial for nonsegmental vitiligo. The company is also evaluating broader strategic opportunities to enhance its pipeline and financial standing.
Looking ahead, VYNE’s management is committed to advancing its strategic review process and pipeline development, with the aim of delivering value to shareholders and addressing significant unmet medical needs in the field of immune-mediated diseases.

