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Anika Therapeutics, Inc. (ANIK)
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Anika Therapeutics (ANIK) AI Stock Analysis

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ANIK

Anika Therapeutics

(NASDAQ:ANIK)

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Neutral 49 (OpenAI - 4o)
Rating:49Neutral
Price Target:
$10.00
▲(2.56% Upside)
Anika Therapeutics' overall stock score is primarily impacted by its financial performance, which reflects significant challenges with declining revenues and persistent losses. While there is some positive momentum in technical analysis and progress in regulatory submissions, these are overshadowed by valuation concerns and mixed earnings call results. The company's focus on improving operational performance and cash flow management is crucial for enhancing its financial health.
Positive Factors
Regulatory Progress
The submission of the third and final PMA module for Hyalofast to the FDA marks a significant regulatory milestone, potentially opening new market opportunities in the U.S. and enhancing long-term growth prospects.
Commercial Channel Growth
The 22% growth in the Commercial Channel, driven by the Integrity product line and international expansion, indicates strong market demand and supports sustainable revenue growth.
Cost Structure Improvements
The reduction in SG&A expenses and overall operating expenses reflects improved cost management, enhancing profitability and cash flow, which are critical for long-term financial health.
Negative Factors
Revenue Decline
The 6% decline in overall revenue highlights challenges in maintaining sales momentum, which could impact long-term growth if not addressed.
OEM Channel Revenue Decline
The 20% decline in OEM channel revenue due to pricing pressure suggests competitive challenges that could affect future revenue streams and market position.
Gross Margin Decrease
A significant decrease in gross margin indicates potential pricing and cost challenges, which could pressure profitability if not managed effectively.

Anika Therapeutics (ANIK) vs. SPDR S&P 500 ETF (SPY)

Anika Therapeutics Business Overview & Revenue Model

Company DescriptionAnika Therapeutics, Inc. (ANIK) is a biopharmaceutical company focused on developing and commercializing innovative products for the orthopedic market. The company specializes in the development of therapies for pain management and tissue regeneration, particularly in the areas of osteoarthritis and joint preservation. Anika's core products include viscosupplements, which are hyaluronic acid-based injections used to alleviate joint pain, as well as regenerative medicine solutions aimed at improving healing and function in musculoskeletal conditions.
How the Company Makes MoneyAnika Therapeutics generates revenue primarily through the sale of its proprietary products, particularly its viscosupplement injections, which are sold to healthcare providers and distributors. The company also earns revenue from licensing agreements and collaborations with other pharmaceutical and biotechnology firms, which may involve upfront payments, milestone payments, and royalties on sales of partnered products. Additionally, Anika pursues research and development contracts that can provide funding and support for its product pipeline. Key partnerships can enhance its market reach and product offerings, contributing significantly to its earnings.

Anika Therapeutics Earnings Call Summary

Earnings Call Date:Nov 05, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 10, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted strong growth in the Commercial Channel, significant progress in regulatory submissions, and improved cost management. However, these positives were offset by revenue declines in key segments and challenges with pricing pressure and study results.
Q3-2025 Updates
Positive Updates
Commercial Channel Revenue Growth
Commercial Channel revenue grew 22%, driven by strong Integrity growth, Hyalofast expansion outside the U.S., and international growth in OA Pain Management.
Integrity Procedures and Growth
Integrity procedures in the U.S. grew for the sixth consecutive quarter, driving Regenerative Solutions growth of 25% year-over-year. The number of surgeon users increased to nearly 300.
Successful Hyalofast PMA Submission
The third and final PMA module for Hyalofast was submitted to the FDA on October 31st, marking a major milestone in the U.S. regulatory pathway.
Cingal Milestone and Progress
Surpassed sales of 1 million Cingal injections since 2016 launch. Progress made towards U.S. NDA submission with successful completion of the first toxicity study.
Cost Structure Improvements
SG&A expenses down 12% year-over-year and overall operating expenses down 3%, leading to improved profitability and free cash flow.
Negative Updates
Revenue Decline
Overall revenue for the quarter was down 6% compared to the same period last year, attributed to pricing stabilization efforts in the U.S. OA Pain Management business.
OEM Channel Revenue Decline
OEM channel revenue declined 20% due to pricing pressure on end-user sales, with Monovisc and Orthovisc sales impacted by reduced pricing.
Gross Margin Decrease
Gross margin decreased by 10 percentage points year-over-year, primarily due to a reduction in Monovisc and Orthovisc sales to J&J.
Hyalofast Study Challenges
Hyalofast U.S. Phase III study did not meet its two co-primary endpoints under the original statistical framework due to disproportionate missing data in the control arm.
Company Guidance
During Anika's third quarter 2025 earnings call, the company provided several key metrics and guidance updates. Anika reported total revenue of $27.8 million, a 6% decrease year-over-year, with Commercial Channel revenue growing by 22% and OEM Channel revenue declining by 20%. The company highlighted strong performance in its Integrity product line, which saw a 25% year-over-year growth in Regenerative Solutions, and international OA Pain Management revenue increased by 21%. Despite the decrease in revenue, Anika maintained its full-year guidance, expecting Commercial Channel revenue between $47 million and $49.5 million, and OEM Channel revenue between $62 million and $65 million. The company also reported a gross margin of 56% and positive adjusted EBITDA of $900,000 for the quarter. Anika remains focused on advancing its product pipeline and regulatory milestones, with significant progress noted in the PMA submission for Hyalofast and ongoing studies for Cingal NDA submission. Additionally, Anika announced a $15 million share repurchase program as part of its capital deployment strategy.

Anika Therapeutics Financial Statement Overview

Summary
Anika Therapeutics faces significant financial challenges, with declining revenues and persistent losses impacting profitability. While the company maintains a strong equity base, operational inefficiencies and cash flow constraints pose risks to financial stability. The focus should be on improving operational performance and cash flow management to enhance financial health.
Income Statement
45
Neutral
Anika Therapeutics has experienced a decline in revenue over the TTM period, with a negative revenue growth rate of -8.84%. The company shows a negative net profit margin of -29.29%, indicating significant losses. The gross profit margin remains relatively healthy at 59.57%, but the negative EBIT and EBITDA margins suggest operational inefficiencies. Overall, the income statement reflects challenges in maintaining profitability and growth.
Balance Sheet
55
Neutral
The balance sheet shows a moderate debt-to-equity ratio of 0.16, indicating manageable leverage. However, the return on equity is negative at -38.50%, reflecting ongoing losses. The equity ratio stands at 77.47%, suggesting a strong equity base relative to total assets. While the company maintains a solid equity position, the negative ROE highlights profitability concerns.
Cash Flow
40
Negative
The cash flow statement reveals a significant decline in free cash flow growth at -221.12%, and the operating cash flow to net income ratio is 0.43, indicating limited cash generation relative to net losses. The free cash flow to net income ratio is low at 0.08, further emphasizing cash flow challenges. Overall, the cash flow position is weak, with limited cash generation and growth.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue80.91M119.91M120.79M113.83M147.79M130.46M
Gross Profit67.19M76.00M82.53M73.22M82.94M69.03M
EBITDA20.24M3.02M15.06M18.16M-4.16M-1.00M
Net Income-33.04M-56.38M-82.67M-14.86M4.13M-23.98M
Balance Sheet
Total Assets189.44M202.74M270.63M349.13M347.54M365.61M
Cash, Cash Equivalents and Short-Term Investments57.99M55.63M68.74M86.33M94.39M98.32M
Total Debt24.51M25.93M27.74M30.89M20.95M22.46M
Total Liabilities42.63M48.75M58.37M63.56M60.45M93.20M
Stockholders Equity146.81M153.99M212.26M285.56M287.08M272.40M
Cash Flow
Free Cash Flow648.00K-2.33M-7.21M-3.08M3.25M11.44M
Operating Cash Flow8.13M5.40M-1.79M4.41M8.40M13.06M
Investing Cash Flow-1.91M-8.33M-5.43M-7.49M-3.12M-71.26M
Financing Cash Flow-10.63M-12.73M-6.32M-4.85M-6.78M-3.77M

Anika Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price9.75
Price Trends
50DMA
9.39
Positive
100DMA
9.56
Negative
200DMA
11.88
Negative
Market Momentum
MACD
0.10
Positive
RSI
45.11
Neutral
STOCH
19.81
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ANIK, the sentiment is Negative. The current price of 9.75 is below the 20-day moving average (MA) of 9.82, above the 50-day MA of 9.39, and below the 200-day MA of 11.88, indicating a neutral trend. The MACD of 0.10 indicates Positive momentum. The RSI at 45.11 is Neutral, neither overbought nor oversold. The STOCH value of 19.81 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ANIK.

Anika Therapeutics Risk Analysis

Anika Therapeutics disclosed 44 risk factors in its most recent earnings report. Anika Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Anika Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$103.88M-20.783.64%16.88%
59
Neutral
$90.61M12.984.34%3.36%-21.15%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$137.29M-8.73%-31.29%65.68%
48
Neutral
$88.66M-2.52-87.61%14.04%-0.65%
42
Neutral
$120.45M-1746.27%20.59%18.61%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ANIK
Anika Therapeutics
9.52
-7.91
-45.38%
FONR
Fonar
14.36
-2.09
-12.71%
RCEL
Avita Medical
3.95
-8.92
-69.31%
NSPR
InspireMD
1.70
-0.88
-34.11%
XTNT
Xtant Medical Holdings
0.65
0.24
58.54%
MODD
Modular Medical
0.49
-1.45
-74.74%

Anika Therapeutics Corporate Events

Anika Therapeutics Reports Mixed Q3 2025 Results
Nov 6, 2025

Anika Therapeutics, Inc. is a leading company in the osteoarthritis pain management and regenerative solutions industry, focusing on early intervention orthopedics. The company is renowned for its innovative hyaluronic acid products aimed at improving patient outcomes globally.

Anika Therapeutics’ Earnings Call: Growth Amid Challenges
Nov 6, 2025

Anika Therapeutics, Inc. recently held its earnings call, revealing a mixed sentiment characterized by notable achievements in commercial growth and regulatory advancements, yet tempered by revenue declines and pricing challenges. The company showcased its progress in cost management and strategic initiatives, but faced hurdles in key segments and study results.

Stock BuybackFinancial DisclosuresProduct-Related AnnouncementsRegulatory Filings and Compliance
Anika Therapeutics Files Final Module for Hyalofast
Positive
Nov 5, 2025

On November 5, 2025, Anika Therapeutics announced the filing of the third and final module of its Premarket Approval application for Hyalofast, a resorbable scaffold for treating knee cartilage defects, and released positive data from its U.S. Phase III clinical trial. The company reported a 6% decrease in third-quarter revenue compared to 2024, despite a 22% increase in Commercial Channel revenue and a significant milestone for Cingal, which surpassed one million injections globally. Anika also announced a $15 million share repurchase plan and reaffirmed its fiscal 2025 guidance, highlighting strong growth in its Integrity Implant System and international OA Pain Management.

The most recent analyst rating on (ANIK) stock is a Hold with a $9.00 price target. To see the full list of analyst forecasts on Anika Therapeutics stock, see the ANIK Stock Forecast page.

Anika Therapeutics’ Integrity Implant System Study: A Market Game Changer?
Oct 27, 2025

Study Overview: Anika Therapeutics, Inc. is conducting a study titled ‘Post Market Confirmatory Interventional Clinical Study of the Integrity Implant System Used for Rotator Cuff Tear Augmentation.’ The study aims to confirm the performance, safety, and clinical benefits of the Integrity Implant System in treating rotator cuff tears. This research is significant as it seeks to validate the effectiveness of a device that could improve outcomes for patients with shoulder injuries.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 06, 2025