Clinical Trial DesignALX Oncology is updating the design of its Phase 2 ASPEN-Breast study to enable a CD47 and HER2 biomarker-driven strategy, which could enhance the trial's effectiveness.
High-Priority ProgramsThe anti-EGFR ADC, ALX2004, remains a high-priority program with significant potential, and the clinical program is on track to begin with the first patient expected to be dosed imminently.
Market OpportunityData suggests that 50-70% of HER2+ breast cancer patients overexpress CD47, representing a large market opportunity for ALX Oncology if the study is successful.