Drug DevelopmentTTI-109, a pro-drug of TTI-101, has a higher bioavailability and is expected to have improved tolerability by reducing GI-related adverse events, which could be significant.
Market ExpansionManagement plans to assess the opportunity to expand TTI-109 into other STAT3-driven indications following the completion of the TTI-109 HV study.
Therapeutic PotentialThere is potential for broad therapeutic relevance with safe STAT3 inhibition, including anti-fibrotic activity that could address several diseases with high unmet need.