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Heron Therapeutics (HRTX)
NASDAQ:HRTX
US Market

Heron Therapeutics (HRTX) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
May 11, 2026
Before Open (Confirmed)
Period Ending
2026 (Q1)
Consensus EPS Forecast
-0.01
Last Year’s EPS
0.01
Same Quarter Last Year
Moderate Buy
Based on 2 Analysts Ratings

Earnings Call Summary

Q4 2025
Earnings Call Date:Feb 26, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call communicated strong commercial inflection and financial progress: record annual revenue (~$155M), improved gross margin (~73%), and adjusted EBITDA of $14.7M, alongside clear Q4 momentum in Acute Care driven by ZYNRELEF (+48% YoY) and APONVIE (+97% YoY). Operational wins (financing completion, J-codes, VAN rollout, CrossLink IGNITE, guideline inclusion) support continued growth. Key risks include ongoing Oncology headwinds from the SUSTOL wind-down (7.8% YoY decline in Oncology revenue), pricing pressure and competition for CINVANTI, the multi-year timeline for ZYNRELEF PFS approval, the need to educate providers on the NOPAIN Act, and litigation uncertainty. Management expects to remain EBITDA positive in 2026 while making targeted commercial investments that may temporarily moderate near-term EBITDA but aim to accelerate longer-term revenue and value creation.
Company Guidance
Heron guided 2026 net product sales of $173–$183 million and adjusted EBITDA of $10–$20 million, saying it expects to remain EBITDA‑positive while making targeted commercial investments that may moderate near‑term EBITDA but accelerate revenue and free‑cash‑flow generation in 2027; this follows FY2025 results of ~$154.9–$155 million in net product sales, adjusted EBITDA of $14.7 million (above prior guidance of $9–$13M) and ~73% gross margin. Management pointed to clear Q4 momentum in Acute Care—Q4 Acute Care net sales of $16.3M (Q3 $12.3M, +33% q/q), ZYNRELEF $12.5M (+48% y/y; Q3 $9.3M) and APONVIE $3.8M (+97% y/y; demand units +101% y/y)—and Oncology net sales of $24.2M (full‑year Oncology ≈$105M, down ~7.8% y/y largely due to SUSTOL wind‑down). They also reiterated a potential mid‑ to late‑2027 approval for a ZYNRELEF prefilled syringe pending 12 months of stability testing plus a 4–6 month regulatory review.
Record Annual Revenue and Improved Profitability
Full year 2025 net product sales of $154.9 million and adjusted EBITDA of $14.7 million (more than doubling prior year performance), beating prior guidance of $9M–$13M. Gross margin approximately 73%, reflecting improved cost discipline and favorable product mix.
Acute Care Quarter Acceleration
Acute Care net sales of $16.3 million in Q4 2025, up ~33% quarter-over-quarter from $12.3 million (Q3). The Acute Care franchise increased more than 57% year-over-year in the quarter, signaling clear momentum heading into 2026.
ZYNRELEF Strong Growth and Reimbursement Progress
ZYNRELEF Q4 net sales of $12.5 million (up from $9.3 million in Q3) and 48% year-over-year revenue growth in the quarter. Reimbursement clarity improved with permanent J-code (J0668) and workflow simplifications (VAN rollout); prefilled syringe (PFS) program progressing with potential approval targeted mid- to late-2027.
APONVIE Rapid Adoption and Guideline Inclusion
APONVIE Q4 net sales $3.8 million, up 97% year-over-year; demand units grew ~101% YoY. Included in the Fifth Consensus Guidelines for PONV and granted a permanent product-specific J-code (J8502). Dedicated hospital-focused sales team (IBM group) launched to accelerate hospital adoption.
Successful Financing and Strong Balance Sheet
Completed a financing in 2025 that eliminated a capital-structure overhang, providing financial flexibility to increase targeted commercial investments and execute growth initiatives.
Concrete 2026 Guidance with Continued Profitability Target
Management provided 2026 guidance of $173M–$183M in net product sales and adjusted EBITDA of $10M–$20M, and reiterated an expectation to remain EBITDA positive while making targeted commercial investments to accelerate growth.
Operational Initiatives Driving Commercial Execution
Implemented CrossLink IGNITE incentive program (expanded into 2026), completed VAN rollout to reduce administration friction, and leveraged permanent coding and guideline inclusion to reduce hospital adoption barriers — all cited as drivers of improved distributor/hospital execution.

Heron Therapeutics (HRTX) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

HRTX Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
May 11, 2026
2026 (Q1)
-0.01 / -
0.01
Feb 26, 2026
2025 (Q4)
-0.02 / -0.02
0.02-200.00% (-0.04)
Nov 04, 2025
2025 (Q3)
-0.01 / -0.10
-0.03-233.33% (-0.07)
Aug 08, 2025
2025 (Q2)
-0.01 / -0.02
-0.0666.67% (+0.04)
May 06, 2025
2025 (Q1)
>-0.01 / 0.01
-0.02150.00% (+0.03)
Feb 27, 2025
2024 (Q4)
-0.03 / 0.02
-0.07128.57% (+0.09)
Nov 12, 2024
2024 (Q3)
-0.04 / -0.03
-0.1782.35% (+0.14)
Aug 06, 2024
2024 (Q2)
-0.04 / -0.06
-0.3582.86% (+0.29)
May 07, 2024
2024 (Q1)
-0.07 / -0.02
-0.2792.59% (+0.25)
Mar 12, 2024
2023 (Q4)
-0.15 / -0.07
-0.1758.82% (+0.10)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

HRTX Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Feb 26, 2026
$1.08$1.20+11.11%
Nov 04, 2025
$1.18$1.14-3.39%
Aug 08, 2025
$1.84$1.32-28.26%
May 06, 2025
$2.13$2.42+13.62%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Heron Therapeutics (HRTX) report earnings?
Heron Therapeutics (HRTX) is schdueled to report earning on May 11, 2026, Before Open (Confirmed).
    What is Heron Therapeutics (HRTX) earnings time?
    Heron Therapeutics (HRTX) earnings time is at May 11, 2026, Before Open (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is HRTX EPS forecast?
          HRTX EPS forecast for the fiscal quarter 2026 (Q1) is -0.01.

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