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Zoetis (ZTS)
NYSE:ZTS

Zoetis (ZTS) AI Stock Analysis

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ZTS

Zoetis

(NYSE:ZTS)

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Outperform 75 (OpenAI - 5.2)
Rating:75Outperform
Price Target:
$145.00
▲(10.60% Upside)
Action:ReiteratedDate:02/13/26
The score is driven primarily by strong, durable financial performance (growth, margins, and cash flow) and a generally positive but cautious earnings outlook. Technicals are improving but still constrained by the longer-term downtrend versus the 200-day average, while valuation is only moderately attractive given the P/E and modest yield.
Positive Factors
Revenue Growth & Margin Durability
Steady top-line expansion paired with consistently high gross and operating margins indicates durable pricing power across products and species. This structural profitability supports reinvestment in R&D and commercial channels, sustaining long-term earnings and resilience to cyclical demand swings.
Strong Cash Generation
Robust and growing operating cash flow and high free-cash-flow conversion provide durable funding for R&D, M&A optionality, and capital returns. Reliable FCF at scale reduces dependence on external financing and enables sustained strategic investment even through near-term revenue variability.
Material Deleveraging & Capital Returns Capacity
Sharp reduction in reported debt materially improves financial flexibility and lowers interest exposure, enabling persistent capital returns without sacrificing investment. Deleveraging, combined with sustained buybacks/dividends, signals disciplined capital allocation and supports long-term shareholder value creation.
Negative Factors
OA Pain (mAb) Franchise Weakness
Material and persistent declines in the OA monoclonal antibody portfolio reduce growth in the Companion Animal segment and undermine a previously meaningful revenue stream. Prolonged weakness may require increased marketing, pricing incentives, or R&D pivots, pressuring margins and long-term revenue growth.
Heightened Competitive & Promotional Intensity
Sustained promotional activity and new product entrants in dermatology and parasiticides can erode pricing power and force higher SG&A spending. If competitive intensity persists, it will pressure margins and require sustained commercial investment, reducing the durability of recent margin expansion.
U.S. Clinic Traffic & Pet-Owner Price Sensitivity
Structural declines in clinic visits and heightened price sensitivity among key demographics can reduce demand for routine and elective treatments over multiple quarters. Lower visit frequency compresses volume growth opportunities for recurring products, making revenue less resilient and increasing reliance on pricing or new launches.

Zoetis (ZTS) vs. SPDR S&P 500 ETF (SPY)

Zoetis Business Overview & Revenue Model

Company DescriptionZoetis Inc. discovers, develops, manufactures, and commercializes animal health medicines, vaccines, and diagnostic products in the United States and internationally. It commercializes products primarily across species, including livestock, such as cattle, swine, poultry, fish, and sheep; and companion animals comprising dogs, cats, and horses. The company also offers vaccines, which are biological preparations to prevent diseases of the respiratory, gastrointestinal, and reproductive tracts or induce a specific immune response; anti-infectives that prevent, kill, or slow the growth of bacteria, fungi, or protozoa; and parasiticides that prevent or eliminate external and internal parasites, which include fleas, ticks, and worms. It also provides other pharmaceutical products that comprise pain and sedation, antiemetic, reproductive, and oncology products; dermatology products for itch associated with allergic conditions and atopic dermatitis; and medicated feed additives, which offer medicines to livestock. In addition, the company provides portable blood and urine analysis testing, including point-of-care diagnostic products, instruments and reagents, rapid immunoassay tests, reference laboratory kits and services, and blood glucose monitors; and other non-pharmaceutical products, including nutritionals and agribusiness services, as well as products and services in areas, such as biodevices, genetics tests, and precision animal health. It markets its products to veterinarians, livestock producers, and retail outlets, as well as third-party veterinary distributors through its sales representatives, and technical and veterinary operations specialists. The company was founded in 1952 and is headquartered in Parsippany, New Jersey.
How the Company Makes MoneyZoetis generates revenue primarily through the sale of its animal health products, which include pharmaceuticals, vaccines, and diagnostic services. The company's revenue model is built on a diverse portfolio of products that cater to various animal species and health needs. Key revenue streams include sales from its Livestock and Companion Animal segments, with livestock products often contributing a substantial portion of revenue due to the scale of agricultural production. Additionally, Zoetis has established significant partnerships with veterinary clinics, animal health distributors, and livestock producers, which enhance its market reach and sales capabilities. The company also invests in research and development to innovate and expand its product offerings, further driving revenue growth through new product launches and market penetration.

Zoetis Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where the company is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsZoetis' revenue growth in the U.S. has been inconsistent, with recent pressures from declining vet visits and competitive dynamics in dermatology impacting performance. However, international markets have shown resilience, with a 6% organic growth driven by strong Companion Animal and Livestock segments. Despite challenges, Zoetis remains optimistic about its diversified portfolio and innovation, with new product approvals expected to bolster future growth. The company revised its full-year revenue guidance, reflecting a cautious outlook amid market headwinds, particularly in the U.S. Companion Animal business.
Data provided by:The Fly

Zoetis Earnings Call Summary

Earnings Call Date:Feb 12, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Apr 30, 2026
Earnings Call Sentiment Positive
The call reflects a fundamentally positive operational performance and financial discipline: solid organic revenue (6%), adjusted net income growth, margin expansion, strong franchises (Simparica, Diagnostics, Livestock), and active capital returns. However, material near-term headwinds remain—most notably weakness in the OA pain monoclonal antibody franchise, increased competitive promotional activity (especially in dermatology and parasiticides), U.S. clinic traffic sensitivity, and one-time international timing effects that complicate quarter-to-quarter comparability. Management provided prudent 2026 guidance that incorporates competition and timing adjustments while highlighting a robust pipeline and long-term growth drivers.
Q4-2025 Updates
Positive Updates
Full-Year Revenue Growth (Organic/Reported)
Reported global revenue of $9.5B, up 2% on a reported basis and 6% on an organic operational basis (driven by ~4% price and ~2% volume).
Adjusted Net Income and EPS Expansion
Adjusted net income of $2.8B, up 6% reported and 7% organic operational; adjusted diluted EPS grew ~6% operationally and 10% on an organic operational basis.
Simparica Franchise Strength
Simparica franchise delivered $1.5B in annual revenue, up 12% operationally; Simparica Trio surpassed $1B in U.S. sales and was a key growth driver (Trio: 13% global operational growth; U.S. Trio ~10% for the year).
Companion Animal Diagnostics Outperformance
Companion Animal Diagnostics grew 13% operationally for the year (10% in Q4); U.S. diagnostics grew 14%—benefiting from launches like VetScan Optocell and AI-enabled Imagyst expansion.
Livestock Portfolio Momentum
Livestock revenue of $2.8B, up 8% organic operationally for the year (international livestock +10% operationally), with strong contributions from poultry, aquaculture (Moritella), cattle and vaccines.
Margin Expansion and FX Tailwind
Full-year adjusted gross margin expanded to 71.9%, up 120 basis points on a reported basis, with foreign exchange benefiting ~80 basis points; margin gains also aided by MFA divestiture and price.
Capital Return and Balance Sheet Actions
Returned >$3.2B via share buybacks and $800M in dividends in 2025; completed convertible bond that supported a $1.75B buyback, while maintaining strong balance sheet capacity for investments.
2026 Financial Guidance
Guidance for 2026: organic operational revenue growth of 3%–5% and organic operational adjusted net income growth of 3%–6%; adjusted net income guided to $2.975B–$3.025B and adjusted diluted EPS $7.00–$7.10.
Negative Updates
U.S. Clinic Traffic and Pet Owner Price Sensitivity
Ongoing economic pressure on Gen Z/millennial pet owners led to declines in therapeutic visits and doses; routine care is more price-sensitive, impacting volumes and compounding competitive headwinds.
Competitive Pressure in Dermatology and Parasiticides
Elevated promotional launch activity and new entrants (including additional oral JAK competitors internationally) led to deceleration in dermatology growth (key dermatology: +6% for year but only +1% in Q4) and increased promotional intensity in parasiticide launches.
OA Pain (mAb) Franchise Weakness
OA pain franchise declined 3% operationally for the year ($568M); Librela down 6% operationally for year and Librela U.S. down ~16% year-over-year (Q4 Librela -32%); overall OA pain Q4 decline ~11% operationally to $137M—material headwind in Companion Animal.
Q4 International Timing Adjustments (One-Time Effects)
Operational changes tied to fiscal-year alignment accelerated international sales into Q4 2025, boosting International segment Q4 by ~2.5%–3.5% (company noted ~30–40 bps of total-company effect); this timing benefit is nonrecurring and complicates comparability.
U.S. Reported Revenue Stagnation
U.S. segment was flat on a reported basis for the year ($5.1B reported), with U.S. Companion Animal facing localized declines—Q4 U.S. OA mAbs down ~25% in the quarter—pressuring near-term U.S. growth.
Manufacturing Cost Pressure in H1
Higher manufacturing costs in the first half related to inventory valued at prior-year standards partially offset margin benefits from price and the MFA divestiture.
Operational Complexity from ERP/Fiscal Alignment
Multiyear ERP transition and contemplated fiscal-year alignment introduce timing shifts and a recast of prior periods; delayed/accelerated order processing and price timing changes create short-term reporting and comparability complexity.
Near-Term Competitive Uncertainty
Company expects heightened competitive intensity in 2026 for key derm and parasiticide categories; management factored promotional activity and competitor launches into conservative guidance assumptions.
Company Guidance
Zoetis guided 2026 to 3%–5% organic operational revenue growth and 3%–6% organic operational adjusted net income growth (foreign exchange assumed as of late January), which on a reported basis implies revenue of $9.825–$10.025 billion and adjusted net income of $2.975–$3.025 billion; adjusted diluted EPS is expected to be $7.00–$7.10 (reported diluted EPS $6.65–$6.75) with an estimated ~$0.22 EPS benefit from recent share repurchases. Key operating assumptions include adjusted cost of sales of ~28% of revenue, adjusted SG&A of $2.43–$2.49 billion, adjusted R&D of $715–$725 million, adjusted interest and other of ~ $200 million, and an adjusted effective tax rate of ~20.5%; guidance reflects contributions from both price and volume (price contribution in line with the company’s normal ~2%–3% range) and does not assume revenues for products or geographies lacking approvals.

Zoetis Financial Statement Overview

Summary
Strong fundamentals supported by steady revenue growth (2020–2024), consistently high margins, and solid free cash flow generation. Balance sheet trends improved with sharply lower reported debt in the latest annual data, though prior years show moderate-to-elevated leverage and 2025 profitability line-item gaps reduce near-term visibility.
Income Statement
84
Very Positive
Revenue has expanded steadily from $6.7B (2020) to $9.3B (2024) with continued growth in 2024 (+8.3%) and strong profitability throughout. Margins are consistently high (2024 gross margin ~69%, operating margin ~36%, net margin ~27%), supporting durable earnings power and pricing strength. Net income also trends upward ($1.6B in 2020 to $2.5B in 2024). A key limitation is that 2025 annual margin details appear missing/zeroed in places (gross profit/EBIT/EBITDA), which reduces visibility into the latest year’s operating trajectory despite net income rising to $2.7B.
Balance Sheet
78
Positive
Leverage improved meaningfully: total debt declined from $6.7B (2024) to $0.2B (2025 annual), while equity stands at $3.3B in 2025. In prior years, leverage was moderate-to-elevated (debt-to-equity ~1.35–1.95 from 2020–2024), but returns on equity were very strong (roughly ~43%–52% from 2020–2024), indicating efficient profitability. The main weakness is the historical reliance on debt (especially 2020–2022) and the notable drop in equity from $4.8B (2024) to $3.3B (2025), which bears watching even as reported debt falls sharply.
Cash Flow
82
Very Positive
Cash generation is solid and scaling: operating cash flow increased from $2.1B (2020) to ~$3.0B (2024), with free cash flow reaching ~$2.3B (2024–2025 annual). Free cash flow growth is strong overall, including a rebound after a 2022 decline and continued expansion into 2024–2025. Cash conversion is generally healthy, with free cash flow running at ~69%–78% of net income (2021–2024). A softer point is that in some years operating cash flow did not fully cover reported earnings (notably 2022 and 2024), suggesting some working-capital or timing effects that can pressure cash conversion intermittently.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue9.47B9.26B8.54B8.08B7.78B
Gross Profit6.67B6.40B5.83B5.48B5.31B
EBITDA4.07B3.87B3.69B3.36B3.17B
Net Income2.67B2.49B2.34B2.11B2.04B
Balance Sheet
Total Assets15.47B14.24B14.29B14.93B13.90B
Cash, Cash Equivalents and Short-Term Investments2.31B1.99B2.04B3.58B3.48B
Total Debt9.49B6.74B6.75B8.09B6.74B
Total Liabilities12.14B9.47B9.29B10.52B9.36B
Stockholders Equity3.33B4.77B5.00B4.41B4.54B
Cash Flow
Free Cash Flow2.28B2.30B1.62B1.33B1.74B
Operating Cash Flow2.90B2.95B2.35B1.91B2.21B
Investing Cash Flow-748.00M-315.00M-777.00M-883.00M-458.00M
Financing Cash Flow-1.87B-2.66B-3.11B-904.00M-1.86B

Zoetis Technical Analysis

Technical Analysis Sentiment
Positive
Last Price131.10
Price Trends
50DMA
125.60
Positive
100DMA
127.83
Positive
200DMA
140.65
Negative
Market Momentum
MACD
1.23
Negative
RSI
60.53
Neutral
STOCH
78.60
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ZTS, the sentiment is Positive. The current price of 131.1 is above the 20-day moving average (MA) of 127.22, above the 50-day MA of 125.60, and below the 200-day MA of 140.65, indicating a neutral trend. The MACD of 1.23 indicates Negative momentum. The RSI at 60.53 is Neutral, neither overbought nor oversold. The STOCH value of 78.60 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ZTS.

Zoetis Risk Analysis

Zoetis disclosed 47 risk factors in its most recent earnings report. Zoetis reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Zoetis Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
$55.34B21.7765.99%1.69%2.68%11.51%
74
Outperform
$2.22B24.2031.80%1.28%33.71%289.48%
70
Outperform
$11.79B18.450.64%10.63%6.35%
64
Neutral
$13.13B-56.60-3.67%3.08%-82.39%
56
Neutral
$17.19B-5.04-21.09%3.99%-6.40%-320.23%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ZTS
Zoetis
131.10
-36.98
-22.00%
RDY
Dr Reddy's Laboratories
14.38
1.68
13.26%
VTRS
Viatris
14.93
6.05
68.13%
PAHC
Phibro Animal Health
54.59
30.46
126.21%
ELAN
Elanco Animal Health
26.40
15.09
133.42%

Zoetis Corporate Events

Dividends
Zoetis Board Declares Second-Quarter 2026 Cash Dividend
Positive
Feb 5, 2026

On February 5, 2026, Zoetis Inc.’s board of directors declared a second-quarter 2026 dividend of $0.53 per share, to be paid on June 2, 2026, to shareholders of record as of April 20, 2026, underscoring the company’s ongoing practice of returning cash to investors. The decision reflects Zoetis’s financial capacity to sustain shareholder distributions and may reinforce its appeal to income-focused investors within the animal health sector.

The most recent analyst rating on (ZTS) stock is a Hold with a $135.00 price target. To see the full list of analyst forecasts on Zoetis stock, see the ZTS Stock Forecast page.

Stock BuybackPrivate Placements and Financing
Zoetis Announces Convertible Notes Offering and Share Repurchases
Positive
Dec 18, 2025

On December 15, 2025, Zoetis announced a proposed private offering of $1.75 billion in convertible senior notes due 2029, with an option for initial purchasers to buy an additional $250 million, targeted exclusively at qualified institutional buyers under Rule 144A. The company plans to use substantially all of the net proceeds to fund capped call transactions and to repurchase its common stock under its existing $6 billion share repurchase program, with buybacks expected to continue through no later than the first quarter of 2026. The capped call structure is designed to mitigate dilution from potential note conversions and manage any excess cash payments, while related hedging and concurrent share repurchases may affect the trading price of Zoetis’ common stock and the notes, underscoring the transaction’s role as both a financing and capital-return mechanism for shareholders.

The most recent analyst rating on (ZTS) stock is a Buy with a $160.00 price target. To see the full list of analyst forecasts on Zoetis stock, see the ZTS Stock Forecast page.

Dividends
Zoetis Announces 6% Increase in Quarterly Dividend
Positive
Dec 11, 2025

On December 11, 2025, Zoetis announced a 6% increase in its quarterly dividend, declaring a dividend of $0.53 per share for the first quarter of 2026. This decision reflects the company’s commitment to delivering value to its shareholders and underscores its strong financial position in the animal health industry.

The most recent analyst rating on (ZTS) stock is a Buy with a $140.00 price target. To see the full list of analyst forecasts on Zoetis stock, see the ZTS Stock Forecast page.

Business Operations and Strategy
Zoetis Hosts Innovation Webcast on Animal Health
Positive
Dec 2, 2025

Zoetis Inc. announced an Innovation Webcast scheduled for December 2, 2025, to discuss the future of animal health. The webcast will highlight the company’s strategic focus on innovation, market opportunities, and the growing demand for advanced therapies in the animal health sector. The event aims to showcase Zoetis’s leadership in the industry, driven by its robust R&D capabilities and market reach, as well as its commitment to sustainable growth through prevention technologies and next-generation solutions.

The most recent analyst rating on (ZTS) stock is a Buy with a $165.00 price target. To see the full list of analyst forecasts on Zoetis stock, see the ZTS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 13, 2026