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Y-Mabs Therapeutics (YMAB)
NASDAQ:YMAB
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Y-Mabs Therapeutics (YMAB) AI Stock Analysis

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YMAB

Y-Mabs Therapeutics

(NASDAQ:YMAB)

Rating:44Neutral
Price Target:
Y-Mabs Therapeutics faces significant challenges with profitability and cash flow despite revenue growth. The technical analysis indicates a bearish trend, and the valuation is not compelling due to negative earnings. While the earnings call presented some positive developments, the strategic realignment must address key challenges to improve the outlook.
Positive Factors
Mergers and Acquisitions
Y-mAbs announced it is being acquired by SERB Pharmaceuticals for a deal value of ~$412M.
Revenue Performance
2Q25 total revenue of $19.5M exceeded guidance of $17 - $19M, while beating consensus of $18.4M.
Stock Premium
SERB Pharmaceuticals announced an offer to acquire YMAB for $8.60/share, representing a ~105% premium to YMAB's closing price.
Negative Factors
Competitive Pressure
Emerging competitive pressure on U.S. sales of DANYELZA and delays from YMAB's earlier stage SADA PRIT assets are factors considered in the fair offer.
Stock Rating Downgrade
The stock rating is downgraded to Neutral from Buy, while the price target is lowered to $8.60.

Y-Mabs Therapeutics (YMAB) vs. SPDR S&P 500 ETF (SPY)

Y-Mabs Therapeutics Business Overview & Revenue Model

Company DescriptionY-mAbs Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the development and commercialization of novel antibody based therapeutic products for the treatment of cancer in the United States. It offers DANYELZA, a monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor for the treatment of pediatric patients with relapsed or refractory high-risk neuroblastoma. The company is also developing DANYELZA that is in Phase II clinical studies for the treatment of patients with first-line neuroblastoma, third-line neuroblastoma, and in relapsed osteosarcoma; GD2-GD3 vaccine that is in Phase II clinical trial for the treatment of Stage 4 high-risk neuroblastoma; and Omburtamab, a murine monoclonal antibody that is in clinical trials for the treatment of central nervous system/ leptomeningeal metastases from neuroblastoma, desmoplastic small round cell tumor, diffuse intrinsic pontine glioma, and other B7-H3 positive tumors. In addition, it is developing Nivatrotamab for the treatment of small cell lung cancer, as well as is in Phase I/II trial for the treatment of refractory GD2 positive adult and pediatric solid tumors; and Lu-omburtamab-DTPA that is in Phase I clinical development for the treatment of medulloblastoma and B7-H3 positive leptomeningeal metastases from solid tumors. The company has a license agreement with Memorial Sloan Kettering Cancer Center and Massachusetts Institute of Technology to develop and commercialize licensed products. Y-mAbs Therapeutics, Inc. was incorporated in 2015 and is headquartered in New York, New York.
How the Company Makes MoneyY-Mabs Therapeutics generates revenue primarily through the development and commercialization of its proprietary therapeutic products. The company earns money by bringing its drug candidates to market, which involves obtaining regulatory approvals, manufacturing the drugs, and distributing them through various healthcare channels. In addition to direct sales of their approved products, Y-Mabs may enter into strategic partnerships or licensing agreements with other pharmaceutical companies to co-develop or market its products, which can provide upfront payments, milestone payments, and royalties. Furthermore, the company may receive government grants or incentives for developing treatments for rare diseases, which can contribute to its revenue stream.

Y-Mabs Therapeutics Earnings Call Summary

Earnings Call Date:Aug 08, 2025
(Q1-2025)
|
% Change Since: |
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Neutral
While the company reported strong growth in Ex-U.S. markets and maintained a solid cash position, challenges in the U.S. market, including a decline in revenues and increased expenses, present ongoing headwinds. The progress in radiopharmaceutical R&D and DANYELZA's inclusion in NCCN guidelines are positive steps, but the projected Q2 revenue decline tempers the overall outlook.
Q1-2025 Updates
Positive Updates
DANYELZA Revenue Growth
DANYELZA net product revenues reached $20.9 million in Q1 2025, representing an 8% increase from the first quarter of the previous year.
Ex-U.S. Market Expansion
Ex-U.S. DANYELZA net product revenues were $7.5 million, marking an 816% increase from the prior year period, driven by growth in Western Asia, Eastern Asia, and Latin America.
Cash Position and Runway
The company maintains a strong cash position with $60.3 million in cash, providing an anticipated runway into 2027 based on current operations.
Radiopharmaceutical R&D Progress
Completion of Part A of the GD2-SADA Phase I clinical trial and dosing of the first patient in the CD38-SADA Phase I clinical trial in relapsed/refractory non-Hodgkin Lymphoma.
Inclusion in NCCN Guidelines
DANYELZA, in combination with chemotherapy, was added to the NCCN guidelines for the treatment of relapsed/refractory neuroblastoma.
Negative Updates
U.S. Revenue Decline
U.S. DANYELZA net product revenues decreased by 28% to $13.4 million due to competitive pressures and ordering patterns of large customers.
Projected Q2 Revenue Decline
Guidance for Q2 2025 total revenue is between $17 million and $19 million, indicating a potential decrease from Q1 2025.
Increased SG&A Expenses
Selling and general administrative expenses increased by $1.7 million to $13.1 million in Q1 2025 compared to the same period in 2024.
Company Guidance
During the Y-mAbs Therapeutics First Quarter 2025 Earnings Conference Call, the company provided a detailed financial and strategic update. For the first quarter of 2025, Y-mAbs reported DANYELZA net product revenues of $20.9 million, marking an 8% increase from the previous year. Ex-U.S. revenues saw a significant rise, totaling $7.5 million, driven primarily by the named patient program in Western Asia. However, U.S. revenues declined by 28% to $13.4 million due to competitive pressures and ordering patterns. The company maintained a strong cash position with $60.3 million, projecting a runway into 2027. Y-mAbs has reiterated its full-year revenue guidance and announced a second-quarter revenue forecast between $17 million and $19 million. The company also highlighted its ongoing Radiopharmaceutical initiatives, including advancements in their GD2-SADA and CD38-SADA Phase I trials.

Y-Mabs Therapeutics Financial Statement Overview

Summary
Y-Mabs Therapeutics shows revenue growth and a strong equity position but struggles with profitability and cash flow sustainability. The biotech industry demands significant R&D investments, reflected in the financials. Although the balance sheet indicates stability, addressing operational losses is crucial for financial improvement.
Income Statement
45
Neutral
Y-Mabs Therapeutics has shown revenue growth over recent years, with total revenue increasing from $20.75 million in 2020 to $87.68 million in 2024. However, the company is still facing significant challenges with profitability. The EBIT and EBITDA margins remain negative, indicating ongoing operational losses. The net profit margin is also negative, highlighting the unprofitable nature of the business at present.
Balance Sheet
60
Neutral
The company maintains a strong equity position with a low debt-to-equity ratio of 0.009 in 2024, suggesting limited financial leverage risk. However, the return on equity remains negative due to net losses, and the equity ratio is robust, reflecting financial stability. The liquidity position, with substantial cash reserves, supports operational needs despite losses.
Cash Flow
40
Negative
Operating cash flow remains negative, indicating cash consumption from operations. Free cash flow has improved slightly but is still negative, showing reliance on financing activities. The operating cash flow to net income ratio suggests continued cash burn, posing challenges to sustainability without external funding.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue85.39M87.69M84.82M65.27M34.90M20.75M
Gross Profit69.63M72.43M73.40M57.70M32.38M18.55M
EBITDA-26.43M-30.67M-24.94M-94.73M-54.49M-119.54M
Net Income-22.22M-29.67M-21.43M-95.57M-55.27M-119.34M
Balance Sheet
Total Assets117.21M119.90M127.87M141.46M212.78M132.05M
Cash, Cash Equivalents and Short-Term Investments62.29M67.23M78.64M105.76M181.56M114.63M
Total Debt3.12M820.00K1.42M1.77M3.63M3.98M
Total Liabilities29.72M27.90M26.88M32.23M32.68M26.21M
Stockholders Equity87.49M92.00M100.98M109.22M180.11M105.84M
Cash Flow
Free Cash Flow-17.92M-15.71M-27.23M-75.92M-103.52M-91.41M
Operating Cash Flow-17.80M-15.71M-27.23M-75.92M-102.56M-91.23M
Investing Cash Flow-127.00K0.000.000.0061.04M-2.79M
Financing Cash Flow2.41M4.31M100.00K84.00K108.31M2.00M

Y-Mabs Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price8.58
Price Trends
50DMA
6.21
Positive
100DMA
5.34
Positive
200DMA
6.22
Positive
Market Momentum
MACD
0.68
Positive
RSI
81.56
Negative
STOCH
85.00
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For YMAB, the sentiment is Positive. The current price of 8.58 is above the 20-day moving average (MA) of 8.53, above the 50-day MA of 6.21, and above the 200-day MA of 6.22, indicating a bullish trend. The MACD of 0.68 indicates Positive momentum. The RSI at 81.56 is Negative, neither overbought nor oversold. The STOCH value of 85.00 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for YMAB.

Y-Mabs Therapeutics Risk Analysis

Y-Mabs Therapeutics disclosed 76 risk factors in its most recent earnings report. Y-Mabs Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Y-Mabs Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$195.45M119.342.17%134.52%
52
Neutral
$287.69M-38.87%
52
Neutral
$174.14M-68.93%-72.45%-28.60%
51
Neutral
$7.89B-0.33-41.61%2.23%23.26%-2.03%
44
Neutral
$388.50M-24.31%-1.34%11.93%
40
Underperform
$283.11M87.26%10.15%
39
Underperform
$196.30M-77.83%43.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
YMAB
Y-Mabs Therapeutics
8.58
-5.41
-38.67%
OMER
Omeros
4.18
0.22
5.56%
GNFT
Genfit SA
3.95
-0.24
-5.73%
RAPT
RAPT Therapeutics
11.30
-4.14
-26.81%
FDMT
4D Molecular Therapeutics
6.47
-9.04
-58.28%
CRBU
Caribou Biosciences
1.89
0.06
3.28%

Y-Mabs Therapeutics Corporate Events

Business Operations and Strategy
Y-mAbs Therapeutics Updates on Business and Clinical Trials
Neutral
Jan 13, 2025

Y-mAbs Therapeutics, Inc. has released a corporate overview presentation on its investor relations website, which includes updates on its business operations, clinical trials, and development pipeline. This presentation is intended for investor meetings and a podium presentation at the J.P. Morgan Healthcare Conference, indicating the company’s ongoing engagement with investors and stakeholders in the biopharmaceutical industry.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 21, 2025