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4D Molecular Therapeutics (FDMT)
NASDAQ:FDMT
US Market
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4D Molecular Therapeutics (FDMT) AI Stock Analysis

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FDMT

4D Molecular Therapeutics

(NASDAQ:FDMT)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
$10.00
▼(-4.67% Downside)
Action:Reiterated
Date:05/09/26
Overall score reflects weak financial performance driven by large losses and sustained cash burn (primary drag), partially offset by a low-debt balance sheet and moderately positive technical setup with the stock trading above key moving averages. Valuation remains hard to assess due to negative earnings and no dividend yield data.
Positive Factors
Engineered AAV vector platform
A proprietary, tissue-targeted AAV vector platform is a durable competitive asset. It underpins multiple pipeline programs, can increase efficacy and tolerability versus non-targeted approaches, and strengthens partner appeal and licensing opportunities across ophthalmology and other indications.
Negative Factors
Sustained high cash burn
Large negative operating and free cash flows indicate ongoing funding needs. Persistent cash burn forces reliance on equity raises, partnerships, or milestone receipts, diluting shareholders or restricting R&D pacing and increasing execution risk over the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Engineered AAV vector platform
A proprietary, tissue-targeted AAV vector platform is a durable competitive asset. It underpins multiple pipeline programs, can increase efficacy and tolerability versus non-targeted approaches, and strengthens partner appeal and licensing opportunities across ophthalmology and other indications.
Read all positive factors

4D Molecular Therapeutics (FDMT) vs. SPDR S&P 500 ETF (SPY)

4D Molecular Therapeutics Business Overview & Revenue Model

Company Description
4D Molecular Therapeutics, Inc., a clinical-stage gene therapy company, develops product candidates using its adeno-associated viruses vectors. It develops a portfolio of gene therapy product candidates focuses in three therapeutic areas: ophthalm...
How the Company Makes Money
FDMT generates revenue primarily through collaboration and licensing arrangements rather than product sales (its programs are clinical-stage and it has not consistently generated recurring commercial product revenue). Under these agreements, FDMT ...

4D Molecular Therapeutics Financial Statement Overview

Summary
Mixed fundamentals typical of a development-stage biotech: revenue scaled meaningfully in 2025/TTM but profitability is very weak with negative gross profit and large operating losses. Balance sheet leverage is low, but ongoing losses and substantial cash burn (negative operating and free cash flow) increase future funding risk.
Income Statement
22
Negative
Balance Sheet
68
Positive
Cash Flow
34
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue88.24M85.21M37.00K20.72M3.13M18.04M
Gross Profit-10.98M77.58M37.00K-76.37M-77.12M-43.32M
EBITDA-179.25M-151.92M-181.14M-108.66M-107.63M-69.81M
Net Income-160.90M-140.11M-160.87M-100.84M-107.49M-71.32M
Balance Sheet
Total Assets512.90M566.71M560.38M339.89M261.85M353.49M
Cash, Cash Equivalents and Short-Term Investments390.89M402.65M424.88M288.23M213.55M247.78M
Total Debt20.54M21.41M24.61M14.67M16.12M16.45M
Total Liabilities61.07M61.05M49.78M32.06M30.51M34.38M
Stockholders Equity451.84M505.66M510.61M307.83M231.34M319.11M
Cash Flow
Free Cash Flow-130.06M-109.08M-138.37M-78.56M-98.22M-78.24M
Operating Cash Flow-129.45M-109.08M-134.59M-75.79M-86.69M-69.13M
Investing Cash Flow-56.03M-92.97M-302.44M115.72M-17.05M-172.68M
Financing Cash Flow124.44M112.96M337.25M156.83M3.08M118.09M

4D Molecular Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price10.49
Price Trends
50DMA
9.48
Negative
100DMA
9.00
Negative
200DMA
8.94
Negative
Market Momentum
MACD
-0.02
Positive
RSI
37.61
Neutral
STOCH
14.85
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FDMT, the sentiment is Negative. The current price of 10.49 is above the 20-day moving average (MA) of 9.64, above the 50-day MA of 9.48, and above the 200-day MA of 8.94, indicating a bearish trend. The MACD of -0.02 indicates Positive momentum. The RSI at 37.61 is Neutral, neither overbought nor oversold. The STOCH value of 14.85 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FDMT.

4D Molecular Therapeutics Risk Analysis

4D Molecular Therapeutics disclosed 87 risk factors in its most recent earnings report. 4D Molecular Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

4D Molecular Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$897.51M-9.27-33.07%-20.34%
52
Neutral
$455.32M-12.91-4.21%121.11%80.74%
52
Neutral
$800.21M-3.35-78.12%7.21%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$478.31M-2.30-36.83%383560.87%20.87%
49
Neutral
$146.82M-1.67-117.86%-20.31%-23.75%
46
Neutral
$333.84M-6.33-0.11%40.79%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FDMT
4D Molecular Therapeutics
8.37
4.57
120.13%
ASMB
Assembly Biosciences
27.42
13.62
98.70%
KRRO
Korro Bio
9.97
-5.74
-36.54%
DSGN
Design Therapeutics
10.70
7.17
203.12%
IMRX
Immuneering
4.87
3.35
220.39%
AURA
Aura Biosciences Inc
7.47
1.55
26.18%

4D Molecular Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board Changes
4D Molecular Therapeutics Consolidates Financial Leadership Under New Role
Positive
Mar 31, 2026
On March 25, 2026, 4D Molecular Therapeutics appointed Chief Financial Officer Kristian Humer as its Principal Accounting Officer, consolidating key financial leadership roles under a single executive. He replaces Ashoo Gupta in this capacity, who...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 09, 2026