Revenue Growth
Vertex Pharmaceuticals reported $2.77 billion in revenue for Q1 2025, representing a 3% growth compared to Q1 2024. U.S. revenue grew by 9% year-over-year.
Product Launches and Approvals
Successful early launches of ALYFTREK and JOURNAVX, with positive feedback from patients and physicians. ALYFTREK approved in the U.S., U.K., and EU, with further approvals expected in Canada, Australia, and Switzerland.
Pipeline Advancements
Four programs in pivotal development are progressing, including Suzetrigine in diabetic peripheral neuropathy and Zimislecel in type 1 diabetes. Enrollment for several programs is on track to complete this year.
R&D and Commercial Expansion
Significant R&D progress with five programs in Phase III and ongoing diversification of the commercial portfolio.
CASGEVY Uptake
Approximately 90 patients have begun the treatment process with CASGEVY, and more than 65 authorized treatment centers have been established globally.
Financial Position
Vertex ended the quarter with $11.4 billion in cash and investments, and increased total revenue guidance for 2025 to $11.85 billion to $12 billion.