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Helix Biopharma Corp. (TSE:HBP)
:HBP
Canadian Market

Helix BioPharma (HBP) AI Stock Analysis

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Helix BioPharma

(TSX:HBP)

Rating:33Underperform
Price Target:
Helix BioPharma faces significant financial challenges with no revenue and continuous losses, resulting in a low financial performance score. Weak market momentum and poor valuation metrics further dampen the stock's attractiveness. Recent corporate events provide some strategic hope, but are not enough to overcome the fundamental financial issues.

Helix BioPharma (HBP) vs. iShares MSCI Canada ETF (EWC)

Helix BioPharma Business Overview & Revenue Model

Company DescriptionHelix BioPharma Corp. operates as an immune-oncology company in Canada. It is developing L-DOS47 for the treatment of non-small cell lung cancer; and V-DOS47 that targets the vascular epithelial growth factor receptor 2. Helix BioPharma Corp. has collaboration agreements with Moffitt Cancer Center to investigate the pharmacodynamics of L-DOS47 and determine the benefits of combining L-DOS47 with immune checkpoint inhibitors; and with ProMab Biotechnologies, Inc. to develop novel antibody and chimeric antigen receptor T-cell therapy to treat multiple myeloma, as well as a license agreements with Xisle Pharma Ventures Trust and National Research of Council Canada. The company is headquartered in Richmond Hill, Canada.
How the Company Makes MoneyHelix BioPharma makes money primarily through the development and commercialization of its proprietary drug candidates. Revenue streams include potential partnerships and licensing agreements with larger pharmaceutical companies, which may involve upfront payments, milestone payments, and royalties on sales of successfully commercialized drugs. The company may also receive funding from government grants and research collaborations. Additionally, Helix BioPharma seeks to raise capital through equity financing to support its research and development efforts and progress its clinical trials.

Helix BioPharma Financial Statement Overview

Summary
Helix BioPharma's financial state is extremely weak, characterized by a lack of revenue generation and ongoing losses. The negative shareholder equity and reliance on external financing highlight financial instability.
Income Statement
5
Very Negative
Helix BioPharma has consistently reported zero revenue over the past several years, indicating a lack of product commercialization or market traction. The company continues to incur significant losses as evidenced by negative EBIT and net income figures, which have not shown improvement. The absence of revenue growth and profitability is a major concern.
Balance Sheet
15
Very Negative
The balance sheet reveals a precarious financial position with negative shareholders' equity, indicating that liabilities exceed assets. The absence of debt suggests no leverage risk, but the negative equity is a critical issue. The equity ratio is also negative, reflecting a lack of financial stability.
Cash Flow
20
Very Negative
The company has managed its cash flow mainly through financing activities, as seen by consistent positive financing cash flow. However, operating cash flows remain deeply negative, highlighting ongoing operational challenges. The lack of free cash flow growth and negative cash flow ratios to net income emphasize the unsustainable nature of operations without external funding.
Breakdown
TTMSep 2024Sep 2023Sep 2022Sep 2021Sep 2020
Income StatementTotal Revenue
0.000.000.000.000.000.00
Gross Profit
-6.00K-14.00K-13.00K-12.00K-173.00K-212.00K
EBIT
-8.40M-9.37M-6.28M-6.54M-9.61M-8.59M
EBITDA
-9.83M-9.38M-6.31M-6.03M-9.46M-8.44M
Net Income Common Stockholders
-9.82M-9.26M-6.29M-6.08M-7.91M-9.01M
Balance SheetCash, Cash Equivalents and Short-Term Investments
120.00K1.08M808.00K3.25M3.56M4.24M
Total Assets
344.00K1.49M1.03M3.73M4.07M4.91M
Total Debt
0.000.000.002.47M3.61M159.00K
Net Debt
-120.00K-1.08M-808.00K-784.00K47.00K-4.08M
Total Liabilities
603.00K1.58M1.87M3.41M5.46M1.93M
Stockholders Equity
-259.00K-90.00K-844.00K319.00K-1.39M2.39M
Cash FlowFree Cash Flow
-3.68M-5.23M-5.54M-6.51M-9.30M-10.84M
Operating Cash Flow
-3.67M-5.22M-5.53M-6.51M-9.30M-10.83M
Investing Cash Flow
15.00K-14.00K-5.00K0.002.02M1.70M
Financing Cash Flow
5.52M5.51M3.09M6.21M6.56M13.10M

Helix BioPharma Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.92
Price Trends
50DMA
0.87
Positive
100DMA
0.89
Positive
200DMA
0.95
Negative
Market Momentum
MACD
<0.01
Positive
RSI
51.20
Neutral
STOCH
39.52
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:HBP, the sentiment is Neutral. The current price of 0.92 is below the 20-day moving average (MA) of 0.94, above the 50-day MA of 0.87, and below the 200-day MA of 0.95, indicating a neutral trend. The MACD of <0.01 indicates Positive momentum. The RSI at 51.20 is Neutral, neither overbought nor oversold. The STOCH value of 39.52 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for TSE:HBP.

Helix BioPharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
TSCOV
77
Outperform
C$64.98M16.8414.51%28.97%
TSMBX
68
Neutral
C$42.94M26.295.32%-4.67%-60.94%
54
Neutral
$5.31B3.29-45.39%2.79%16.77%-0.07%
TSBCT
43
Neutral
C$25.95M-478.64%56.78%
TSHBP
33
Underperform
C$68.22M685.26%-50.29%
TSDTC
30
Underperform
$44.87M281.56%71.24%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:HBP
Helix BioPharma
0.92
-0.16
-14.81%
TSE:COV
Covalon Technologies
2.37
0.37
18.50%
TSE:BCT
BriaCell Therapeutics
4.71
-25.89
-84.61%
TSE:MBX
Microbix Biosystms
0.30
-0.04
-11.76%
TSE:DTC
Defence Therapeutics
0.82
-0.24
-22.64%

Helix BioPharma Corporate Events

Executive/Board ChangesBusiness Operations and Strategy
Helix BioPharma Strengthens Leadership Team to Drive Growth
Positive
Apr 24, 2025

Helix BioPharma Corp. has announced the appointment of Veronika Kandziora as Chief Operating Officer and Jessica Kourniaktis as Director of Communications. These strategic appointments are aimed at accelerating the company’s growth and enhancing its mission to address hard-to-treat cancers. Kandziora brings extensive leadership experience and deep institutional knowledge, while Kourniaktis offers a unique blend of communication expertise and life sciences insight. These changes are expected to strengthen Helix’s operational structure and stakeholder engagement, positioning the company for future success in the oncology sector.

Spark’s Take on TSE:HBP Stock

According to Spark, TipRanks’ AI Analyst, TSE:HBP is a Underperform.

Helix BioPharma faces significant financial challenges with continuous losses and no revenue generation, severely impacting its overall score. Technical indicators suggest weak market momentum, and the valuation metrics highlight the company’s lack of profitability. However, recent corporate events provide a glimpse of potential strategic improvements, though they are insufficient to outweigh the financial concerns.

To see Spark’s full report on TSE:HBP stock, click here.

Executive/Board ChangesBusiness Operations and Strategy
Helix BioPharma Appoints New CEO to Propel Clinical Advancements
Positive
Apr 10, 2025

Helix BioPharma Corp. has appointed Dr. Thomas Mehrling as its new CEO to lead the company’s ambitious clinical development plans. Dr. Mehrling, with extensive experience in pharmaceutical oncology, aims to advance Helix’s pipeline, including the L-DOS47 Phase II study for non-small cell lung cancer. This strategic leadership change is expected to strengthen Helix’s position in the oncology industry and support its growth objectives.

Spark’s Take on TSE:HBP Stock

According to Spark, TipRanks’ AI Analyst, TSE:HBP is a Underperform.

Helix BioPharma faces significant financial challenges with continuous losses and no revenue generation, severely impacting its overall score. Technical indicators suggest weak market momentum, and the valuation metrics highlight the company’s lack of profitability. However, recent corporate events provide a glimpse of potential strategic improvements, though they are insufficient to outweigh the financial concerns.

To see Spark’s full report on TSE:HBP stock, click here.

Business Operations and Strategy
Helix BioPharma Engages ITG for Market-Making Services
Neutral
Apr 3, 2025

Helix BioPharma Corp. has engaged Independent Trading Group (ITG) to provide market-making services to enhance the liquidity of its common shares, subject to regulatory approval. This agreement, which involves ITG trading shares on the TSX and other venues, aims to maintain a reasonable market for Helix’s shares, potentially improving the company’s market presence and attractiveness to investors.

Executive/Board ChangesPrivate Placements and FinancingShareholder MeetingsStock SplitBusiness Operations and Strategy
Helix BioPharma Corp. Announces Key Decisions from Annual Meeting
Positive
Mar 26, 2025

Helix BioPharma Corp. announced the results of its Annual General and Special Meeting, where shareholders voted overwhelmingly in favor of all business items. Key resolutions approved include the re-election of directors, appointment of auditors, asset transactions, a financing facility, a share consolidation, and a company name change to ‘Aconara Pharma Corp.’ These decisions are poised to impact the company’s operational strategies and market positioning, potentially enhancing its financial flexibility and corporate identity.

Financial Disclosures
Helix BioPharma Releases Interim Financial Statements for January 2025
Neutral
Mar 18, 2025

Helix BioPharma Corp. announced the filing of its unaudited interim financial statements for the three and six-month periods ending January 31, 2025. This filing includes the management’s discussion and analysis and certifications from the CEO and CFO. The release of these financial statements is a routine disclosure that provides stakeholders with insights into the company’s financial health and operational progress, potentially impacting investor confidence and market positioning.

Product-Related AnnouncementsBusiness Operations and Strategy
Helix BioPharma to Present Promising Cancer Treatment Findings at EMIM 2025
Positive
Mar 11, 2025

Helix BioPharma Corp. announced a poster presentation at the European Molecular Imaging Meeting in Bilbao, Spain, showcasing the effects of its Tumour Defence Breaker™, L-DOS47, on CEACAM6-expressing tumors. The study demonstrated that L-DOS47 effectively neutralizes the acidic tumor microenvironment, which is crucial for tumor progression, and showed promising results in head and neck cancer and colon adenocarcinoma models. These findings suggest that L-DOS47 could make hard-to-treat cancers more susceptible to treatment, potentially enhancing Helix’s position in the oncology field.

Executive/Board ChangesBusiness Operations and Strategy
Helix BioPharma Enhances Leadership with Oncology Experts
Positive
Mar 11, 2025

Helix BioPharma Corp. has strengthened its leadership team by appointing three renowned experts in oncology and drug development. These strategic hires are aimed at advancing Helix’s clinical development and discovery strategies, particularly in enhancing the efficacy of immune-oncology therapies and developing next-generation targeted therapies. The new appointments are expected to significantly impact Helix’s operations and bolster its position in the oncology industry.

Private Placements and FinancingShareholder MeetingsBusiness Operations and Strategy
Helix BioPharma Extends Meeting for Key Approvals
Neutral
Mar 4, 2025

Helix BioPharma Corp. has announced the extension of its Annual General and Special Meeting to March 26, 2025, to allow more time for shareholder approval of proposed asset acquisitions from Laevoroc Immunology AG and Laevoroc Chemotherapy AG, as well as a proposed financing strategy. This extension, approved by the Ontario Superior Court of Justice, is a strategic move to strengthen the company’s asset base and financial positioning, potentially impacting its market standing and stakeholder interests.

Private Placements and FinancingM&A TransactionsShareholder MeetingsBusiness Operations and Strategy
Helix BioPharma Postpones Meeting to Finalize Asset Acquisitions and Financing
Neutral
Feb 22, 2025

Helix BioPharma Corp. has postponed its Annual General and Special Meeting to March 26, 2025, to allow more time for shareholder approval on significant asset acquisitions from Laevoroc Immunology AG and Laevoroc Chemotherapy AG, along with a proposed financing strategy. This extension, supported by the Toronto Stock Exchange and pending a court application, highlights Helix’s strategic efforts to enhance its operational capabilities and financial structure, which could potentially strengthen its position in the oncology sector.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.