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Helix BioPharma (TSE:HBP)
TSX:HBP
Canadian Market
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Helix BioPharma (HBP) AI Stock Analysis

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TSE:HBP

Helix BioPharma

(TSX:HBP)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
C$1.50
▼(-37.50% Downside)
Action:Reiterated
Date:04/09/26
The score is held back primarily by weak financial performance (no revenue, ongoing losses and cash burn) and a bearish technical setup (negative MACD and price below key moving averages). Low leverage and a positive equity base provide some support, but valuation metrics are not helpful due to negative earnings and no dividend yield data.
Positive Factors
Asset-light R&D model
Helix’s business centers on R&D and managing a pipeline of preclinical and clinical oncology assets rather than operating a broad commercial business. This asset-light model lowers fixed commercial costs, concentrates capital on science, and supports scalable value creation via licensing or partnerships over months to years.
Negative Factors
No revenue
The company reports no revenue, reflecting a purely developmental-stage profile. Absence of commercial cash inflows means perpetual reliance on external funding for operations and trials, raising execution and financing risk and making long-term viability contingent on successful clinical or licensing events.
Read all positive and negative factors
Positive Factors
Negative Factors
Asset-light R&D model
Helix’s business centers on R&D and managing a pipeline of preclinical and clinical oncology assets rather than operating a broad commercial business. This asset-light model lowers fixed commercial costs, concentrates capital on science, and supports scalable value creation via licensing or partnerships over months to years.
Read all positive factors

Helix BioPharma (HBP) vs. iShares MSCI Canada ETF (EWC)

Helix BioPharma Business Overview & Revenue Model

Company Description
Helix BioPharma Corp. operates as an immune-oncology company in Canada. It is developing L-DOS47 for the treatment of non-small cell lung cancer; and V-DOS47 that targets the vascular epithelial growth factor receptor 2. Helix BioPharma Corp. has ...
How the Company Makes Money
null...

Helix BioPharma Financial Statement Overview

Summary
Financials reflect a development-stage biotech: no revenue, persistent losses (TTM net loss about $4.2M), and ongoing cash burn (TTM free cash flow about -$3.7M). The key offset is modest leverage in the latest period (TTM debt-to-equity ~0.02) and meaningful equity (~$15.4M), which helps reduce near-term balance sheet risk.
Income Statement
9
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownTTMJul 2025Jul 2024Jul 2023Oct 2022Oct 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-4.00K-10.00K-14.00K-13.00K-12.00K-173.00K
EBITDA-3.94M-5.21M-9.38M-6.31M-6.03M-9.46M
Net Income-4.20M-5.21M-9.26M-6.29M-6.08M-7.91M
Balance Sheet
Total Assets18.52M18.80M1.49M1.03M3.73M4.07M
Cash, Cash Equivalents and Short-Term Investments31.00K65.00K1.08M808.00K3.25M3.56M
Total Debt359.00K335.00K0.000.002.47M3.61M
Total Liabilities3.16M3.22M1.58M1.87M3.41M5.46M
Stockholders Equity15.36M15.59M-90.00K-844.00K319.00K-1.39M
Cash Flow
Free Cash Flow-3.71M-3.83M-5.23M-5.54M-6.51M-9.30M
Operating Cash Flow-3.71M-3.83M-5.22M-5.53M-6.51M-9.30M
Investing Cash Flow0.0017.00K-14.00K-5.00K0.002.02M
Financing Cash Flow1.74M2.80M5.51M3.09M6.21M6.56M

Helix BioPharma Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.40
Price Trends
50DMA
1.84
Negative
100DMA
1.97
Negative
200DMA
1.97
Negative
Market Momentum
MACD
-0.08
Positive
RSI
34.41
Neutral
STOCH
1.84
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:HBP, the sentiment is Negative. The current price of 2.4 is above the 20-day moving average (MA) of 1.84, above the 50-day MA of 1.84, and above the 200-day MA of 1.97, indicating a bearish trend. The MACD of -0.08 indicates Positive momentum. The RSI at 34.41 is Neutral, neither overbought nor oversold. The STOCH value of 1.84 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:HBP.

Helix BioPharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
C$207.27M-3.81-51.42%6.61%
46
Neutral
C$120.68M-55.85-66.34%69.04%
42
Neutral
C$37.12M-4.40-103.51%57.98%
41
Neutral
C$29.21M-12.9372.34%26.83%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:HBP
Helix BioPharma
1.58
0.63
66.32%
TSE:MSCL
Satellos Bioscience
9.57
1.65
20.83%
TSE:ARCH
Arch Biopartners
0.44
-1.26
-74.12%
TSE:MDNA
Medicenna Therapeutics Corp
0.47
-0.67
-58.77%
TSE:METX
ME Therapeutics Holdings, Inc.
2.00
-8.30
-80.58%
TSE:ONCO
Onco-Innovations Ltd.
1.47
0.02
1.38%

Helix BioPharma Corporate Events

Business Operations and StrategyProduct-Related Announcements
Helix BioPharma Showcases CEACAM6-Targeted ADC Advances at World ADC London
Positive
Feb 24, 2026
Helix BioPharma unveiled new data on its CEACAM6-directed antibody-drug conjugate program at the 16th Annual World ADC London conference, highlighting a proprietary VHH-based nanobody with tumor-selective binding. The company said the data support...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 09, 2026