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Medicenna Therapeutics Corp (TSE:MDNA)
TSX:MDNA
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Medicenna Therapeutics Corp (MDNA) AI Stock Analysis

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TSE:MDNA

Medicenna Therapeutics Corp

(TSX:MDNA)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
C$0.39
▼(-55.00% Downside)
Action:Reiterated
Date:06/27/26
The score is primarily constrained by weak financial performance driven by no revenue, recurring losses, and sustained cash burn, alongside a shrinking equity base that elevates funding/dilution risk. Technicals also lean bearish with the stock trading below major moving averages and negative MACD. Valuation is not supportive due to a negative P/E and no dividend yield.
Positive Factors
Platform engineering for cytokine therapies
A platform engineering approach to interleukin and cytokine candidates provides a durable competitive edge: it can produce multiple optimized assets with potentially better efficacy/toxicity profiles, support combination strategies, and enable licensing or partner-led commercialization paths over years.
Negative Factors
No revenue and persistent losses
The absence of revenue means the business relies entirely on external financing to fund operations and de-risks only through clinical success. Persistent, material losses undermine internal funding capacity and lengthen the path to self-sustaining operations, increasing execution risk.
Read all positive and negative factors
Positive Factors
Negative Factors
Platform engineering for cytokine therapies
A platform engineering approach to interleukin and cytokine candidates provides a durable competitive edge: it can produce multiple optimized assets with potentially better efficacy/toxicity profiles, support combination strategies, and enable licensing or partner-led commercialization paths over years.
Read all positive factors

Medicenna Therapeutics Corp (MDNA) vs. iShares MSCI Canada ETF (EWC)

Medicenna Therapeutics Corp Business Overview & Revenue Model

Company Description
Medicenna Therapeutics Corp. is an immunotherapy firm focused on creating and commercializing Superkines and "empowered Superkines" to combat cancer and various other illnesses. Their primary candidate, MDNA55, an interleukin-4 (IL-4) empowered cy...
How the Company Makes Money
null...

Medicenna Therapeutics Corp Financial Statement Overview

Summary
Financials reflect a development-stage biotech profile: no revenue, persistent and sizeable operating losses, and ongoing negative operating cash flow/free cash flow (cash burn). Low leverage is a positive, but the sharp decline in stockholders’ equity in the latest year increases funding and dilution risk.
Income Statement
18
Very Negative
Balance Sheet
38
Negative
Cash Flow
16
Very Negative
BreakdownMar 2026Mar 2025Mar 2023Mar 2022Mar 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-77.00K-55.00K-5.00K-38.00K-40.00K
EBITDA-23.63M-12.97M-16.30M-22.54M-17.25M
Net Income-18.41M-11.80M1.55M-22.65M-17.18M
Balance Sheet
Total Assets8.45M28.38M36.45M23.46M42.25M
Cash, Cash Equivalents and Short-Term Investments6.25M24.84M33.60M20.54M40.38M
Total Debt119.00K168.00K0.000.0034.00K
Total Liabilities5.97M9.29M6.96M2.62M4.11M
Stockholders Equity2.48M19.09M29.49M20.84M38.15M
Cash Flow
Free Cash Flow0.00-16.52M-12.66M-23.58M-15.31M
Operating Cash Flow-17.92M-16.49M-12.66M-23.58M-15.31M
Investing Cash Flow2.00K-33.00K-13.05M10.05M5.01M
Financing Cash Flow-19.00K23.49M24.76M3.88M18.26M

Medicenna Therapeutics Corp Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.86
Price Trends
50DMA
0.45
Negative
100DMA
0.58
Negative
200DMA
0.85
Negative
Market Momentum
MACD
-0.02
Negative
RSI
35.49
Neutral
STOCH
6.67
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:MDNA, the sentiment is Negative. The current price of 0.86 is above the 20-day moving average (MA) of 0.40, above the 50-day MA of 0.45, and above the 200-day MA of 0.85, indicating a bearish trend. The MACD of -0.02 indicates Negative momentum. The RSI at 35.49 is Neutral, neither overbought nor oversold. The STOCH value of 6.67 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:MDNA.

Medicenna Therapeutics Corp Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
C$56.62M34.343.31%-3.44%-57.64%
52
Neutral
C$264.76M-1.75-51.42%6.61%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
C$57.06M-21.6870.15%16.99%
41
Neutral
C$28.33M-1.65-103.51%-42.77%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:MDNA
Medicenna Therapeutics Corp
0.37
-0.52
-58.52%
TSE:MSCL
Satellos Bioscience
12.14
5.18
74.43%
TSE:ARCH
Arch Biopartners
0.85
-0.90
-51.43%
TSE:COV
Covalon Technologies
2.07
-0.35
-14.46%
TSE:METX
ME Therapeutics Holdings, Inc.
1.99
-3.01
-60.20%
TSE:ONCO
Onco-Innovations Ltd.
1.47
0.00
0.00%

Medicenna Therapeutics Corp Corporate Events

Business Operations and StrategyProduct-Related Announcements
Medicenna to Highlight MDNA113 Data at 2026 Bloom Burton Healthcare Investor Conference
Positive
Apr 14, 2026
Medicenna Therapeutics will showcase its latest corporate developments and preclinical data on its MDNA113 bifunctional immunotherapy candidate at the 2026 Bloom Burton Co. Healthcare Investor Conference in Toronto on April 21-22. President and C...
Business Operations and StrategyExecutive/Board Changes
Medicenna Taps Pembrolizumab Veteran as CMO to Steer Superkine Immunotherapy Pipeline
Positive
Apr 9, 2026
Medicenna Therapeutics has appointed veteran oncology drug developer Dr. Nageatte Ibrahim as Chief Medical Officer in a fractional role, drawing on her extensive experience at Innovent Biologics, Merck, GSK, and leading academic institutions to gu...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 27, 2026