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BriaCell Therapeutics Corp (TSE:BCT)
TSX:BCT

BriaCell Therapeutics (BCT) AI Stock Analysis

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TSE:BCT

BriaCell Therapeutics

(TSX:BCT)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
C$15.00
▲(40.98% Upside)
The score is held down primarily by weak financial performance (no revenue, widening losses, and significant cash burn with likely ongoing financing needs). Technicals are mixed with some shorter-term strength but negative MACD and a price still far below the 200-day average. Valuation contributes limited support due to a negative P/E and no dividend yield.
Positive Factors
Pivotal Phase 3 progress
Advancing enrollment in a pivotal, randomized Phase 3 with >160 patients and an interim event trigger materially reduces binary development risk versus early-stage programs. Continued recruitment and a near-term readout (1H2026) sustain the company’s pathway to potential approval and partner interest.
Biomarker-driven clinical signals
Consistent Phase 2 survival signals and Phase 3 biomarker correlations (NLR, Th1 cytokine signatures) support patient selection and may enhance observed efficacy in registrational analyses. Durable biomarker strategies improve regulatory and commercial prospects by targeting responders and reducing uncertainty in pivotal outcomes.
Strategic R&D collaborations and pipeline expansion
Partnering with an AI-driven discovery firm to build a small-molecule franchise diversifies BriaCell beyond cell-based immunotherapies. This structural move can broaden addressable markets, accelerate lead discovery, and create longer-term value streams and licensing opportunities independent of a single vaccine program.
Negative Factors
Persistent cash burn
Sustained, large negative operating cash flow and growing net losses are durable constraints: they force repeated external financing, dilute shareholders, and can limit the company’s ability to independently fund late-stage activities or scale manufacturing without partnerships or capital raises.
Shrinking equity base and modest assets
A markedly reduced equity base and relatively small asset cushion leave limited financial flexibility. Even with no debt, accumulated losses and past dilution signal reliance on external capital and raise execution risk for capital-intensive pivotal and commercialization activities over the coming months.
Limited internal resources and scale
A very small headcount constrains in-house capabilities for complex activities—large-scale manufacturing, regulatory submissions, and commercialization. Reliance on external vendors and partners increases costs, coordination risk, and execution dependency during pivotal readouts and potential launch planning.

BriaCell Therapeutics (BCT) vs. iShares MSCI Canada ETF (EWC)

BriaCell Therapeutics Business Overview & Revenue Model

Company DescriptionBriaCell Therapeutics Corp., an immuno-oncology-focused biotechnology company, engages in developing immunotherapies for the management of cancer. Its lead drug candidate is Bria-IMT, a whole-cell cancer vaccine that is in Phase I/IIa clinical trials in combination with the immunotherapy development candidates retifanlimab. The company is also developing Bria-OTS, an off-the-shelf personalized immunotherapy for advanced breast cancer; and BriaDx, a diagnostic test that determines the patients' HLA types. It has a non-exclusive clinical trial collaboration with Incyte Corporation to evaluate the effects of combinations of novel clinical candidates; and a cooperative research and development agreement with the National Cancer Institute to conduct preclinical studies to develop and test Bria-OTS cellular immunotherapy as a treatment for cancer. BriaCell Therapeutics Corp. is based in West Vancouver, Canada.
How the Company Makes MoneyBriaCell Therapeutics makes money through a combination of research and development partnerships, grants, and potential future revenue from the commercialization of its cancer immunotherapy products. Revenue streams are primarily tied to the successful progression of its clinical trials and subsequent partnerships or licensing agreements with larger pharmaceutical companies. Additionally, BriaCell may receive funding from government and non-profit organizations interested in advancing cancer treatment research. The company's focus on developing proprietary immunotherapy solutions aims to establish a foothold in the oncology market, ultimately generating revenue through the sale and licensing of its therapies once they receive regulatory approval.

BriaCell Therapeutics Financial Statement Overview

Summary
Very weak fundamentals driven by a pre-revenue profile, widening net losses in the latest TTM, and substantial ongoing operating/free-cash-flow burn. Low debt reduces leverage risk, but sharply declining equity and continued funding needs increase dilution/financing risk.
Income Statement
8
Very Negative
The company remains pre-revenue (revenue is 0 across all periods provided), with consistently negative gross profit and large operating losses. Losses widened materially in the latest TTM (Trailing-Twelve-Months) period (net loss of ~-38.9M) versus the most recent annual period (~-36.5M), indicating a higher spend profile without offsetting revenue traction. While R&D-stage losses can be normal for biotechnology, the absence of revenue and expanding losses weigh heavily on income statement quality.
Balance Sheet
52
Neutral
Leverage appears very low (total debt is 0 in recent periods), which reduces financial risk versus many cash-burning peers. However, equity has been volatile (negative in some historical years and down sharply from ~57.3M in 2021 to ~10.0M in the latest TTM (Trailing-Twelve-Months)), signaling significant dilution and/or accumulated losses over time. Assets are relatively modest (~13.1M in the latest TTM (Trailing-Twelve-Months)), so the balance sheet provides some cushion, but the shrinking equity base is a clear vulnerability.
Cash Flow
10
Very Negative
Cash burn remains substantial and persistent: operating cash flow is deeply negative in the latest TTM (Trailing-Twelve-Months) (~-31.9M) and free cash flow is similarly negative, implying ongoing funding needs. While free cash flow growth turned positive in the latest TTM (Trailing-Twelve-Months), absolute free cash flow is still meaningfully negative, and cash outflows are large relative to earnings losses (cash burn roughly tracks reported losses). Overall, cash flow quality is weak due to continued high burn and dependence on external capital.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-147.89K-114.04K-20.49K-19.39K-19.44K
EBITDA-36.63M-45.91K-27.23M-34.05M-6.95M
Net Income-36.50M-6.62K-20.30M-11.58M-2.90M
Balance Sheet
Total Assets21.65M5.87M27.16M42.58M58.04M
Cash, Cash Equivalents and Short-Term Investments17.87M862.09K21.25M41.04M57.27M
Total Debt0.000.000.000.0025.99K
Total Liabilities4.32M8.56M30.94M32.25M782.24K
Stockholders Equity24.72M-2.38M-3.78M10.33M57.26M
Cash Flow
Free Cash Flow-28.17M-24.58M-23.74M-12.48M-7.75M
Operating Cash Flow-28.17M-24.13M-23.74M-12.48M-7.75M
Investing Cash Flow-7.65M-681.80K0.000.000.00
Financing Cash Flow45.45M4.42M3.95M-3.74M65.00M

BriaCell Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price10.64
Price Trends
50DMA
10.58
Negative
100DMA
12.82
Negative
200DMA
22.13
Negative
Market Momentum
MACD
-1.35
Negative
RSI
37.54
Neutral
STOCH
8.66
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:BCT, the sentiment is Negative. The current price of 10.64 is above the 20-day moving average (MA) of 6.96, above the 50-day MA of 10.58, and below the 200-day MA of 22.13, indicating a bearish trend. The MACD of -1.35 indicates Negative momentum. The RSI at 37.54 is Neutral, neither overbought nor oversold. The STOCH value of 8.66 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:BCT.

BriaCell Therapeutics Risk Analysis

BriaCell Therapeutics disclosed 50 risk factors in its most recent earnings report. BriaCell Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BriaCell Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
C$31.23M-15.19-8.01%-26.81%-161.24%
44
Neutral
C$35.28M-0.08-409.25%62.01%
41
Neutral
C$18.46M-4.3495.76%22.56%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:BCT
BriaCell Therapeutics
5.73
-51.97
-90.07%
TSE:DOSE
Rapid Dose Therapeutics Corp
0.15
-0.05
-23.68%
TSE:MBX
Microbix Biosystms
0.24
-0.26
-51.52%
TSE:RVX
Resverlogix
0.11
0.05
110.00%
TSE:GSD
Devonian Health Group
11.50
0.70
6.48%
TSE:TTI
Thiogenesis Therapeutics Corp
0.60
-0.04
-6.25%

BriaCell Therapeutics Corporate Events

Business Operations and Strategy
BriaCell Imaging Data Show Tumor Regression and Immune Activation in Metastatic Breast Cancer Trial
Positive
Jan 28, 2026

BriaCell Therapeutics has released new imaging data from its Phase 2 study of Bria-IMT in heavily pre-treated metastatic breast cancer patients, showing regression and resolution of metastatic lesions in the eye orbit, temporal lobe of the brain, liver, and spine, as well as evidence of robust CD8+ T-cell activation and tumor infiltration. Among the 54 patients treated with the Bria-IMT regimen plus a checkpoint inhibitor, no treatment-related discontinuations have been reported to date, and several patients with extensive prior therapy remain alive beyond two years, underscoring the potential durability and safety of Bria-IMT as it progresses into a pivotal Phase 3 trial and potentially strengthens BriaCell’s position in the immuno-oncology landscape.

The most recent analyst rating on (TSE:BCT) stock is a Hold with a C$6.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell Reports Prolonged Survival in Phase 2 Metastatic Breast Cancer Trial
Positive
Jan 27, 2026

BriaCell Therapeutics reported updated Phase 2 data for its Bria-IMT immunotherapy regimen in metastatic breast cancer, showing that 9 of 25 patients treated since 2022 remain alive more than 18 to 47 months after enrollment, markedly exceeding survival benchmarks reported for standard-of-care therapies in comparable late-stage populations. The company highlighted detailed cases of heavily pretreated women, including patients previously exposed to antibody-drug conjugates such as Enhertu and Trodelvy, who achieved prolonged survival and, in some instances, significant disease control without Bria-IMT–related treatment discontinuations. Comparative analyses suggest that Bria-IMT plus checkpoint inhibitor therapy may deliver higher one- and two-year survival rates than several referenced regimens, supporting BriaCell’s view that its approach could address a substantial unmet need in metastatic breast cancer and reinforcing the strategic importance of its ongoing pivotal Phase 3 trial, which is designed to confirm overall survival benefits and potentially reposition the company within the competitive oncology landscape.

The most recent analyst rating on (TSE:BCT) stock is a Hold with a C$6.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyDelistings and Listing ChangesPrivate Placements and Financing
BriaCell Raises $30 Million Through Public Offering of Units and Listed Warrants
Positive
Jan 14, 2026

BriaCell Therapeutics has priced a best-efforts public offering of 5,366,726 units, each comprising one common share or pre-funded warrant and one warrant, at $5.59 per unit for expected gross proceeds of approximately $30 million before fees and expenses. The warrants, exercisable at $6.93 per share for five years, have been approved for listing on the Nasdaq Capital Market under the symbol BCTXL starting January 14, 2026, with the offering slated to close on January 15, 2026, subject to customary conditions; BriaCell plans to use the net proceeds to support working capital, general corporate purposes and advancement of its business objectives, reinforcing its funding base as it progresses its immunotherapy pipeline.

The most recent analyst rating on (TSE:BCT) stock is a Sell with a C$9.50 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Reports Year-Long Complete Lung Metastasis Response in Breast Cancer Trial
Positive
Jan 13, 2026

BriaCell Therapeutics reported an 11‑month sustained complete resolution of a lung metastasis in a 78‑year‑old patient with hormone receptor–positive, HER2‑negative metastatic breast cancer treated with its personalized off‑the‑shelf immunotherapy Bria‑OTS in a Phase 1/2a study. The patient, who had failed multiple prior treatments, showed 100% disappearance of a lung tumor after four doses of Bria‑OTS monotherapy, with the response repeatedly confirmed over nearly a year, no treatment‑limiting toxicities observed, and stable disease at other evaluable sites; BriaCell has completed the Phase 1 dose escalation and is now advancing the Phase 2a dose‑expansion stage combining Bria‑OTS with an immune checkpoint inhibitor, a step that could strengthen its position in the metastatic breast cancer treatment landscape and underscore the platform’s potential safety and efficacy for patients with limited options.

The most recent analyst rating on (TSE:BCT) stock is a Sell with a C$9.50 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell’s Phase 3 Breast Cancer Trial Named a 2026 ‘Clinical Trial to Watch’ by Nature Medicine
Positive
Dec 18, 2025

BriaCell Therapeutics’ pivotal Phase 3 trial of its lead immunotherapy candidate Bria-IMT in metastatic breast cancer has been highlighted by Nature Medicine as one of the “clinical trials to watch in 2026,” underscoring rising scientific and clinical interest in the program. The BRIA-ABC study, which compares Bria-IMT plus an immune checkpoint inhibitor against physician’s choice therapy in a broad, real‑world metastatic breast cancer population, has screened more than 230 patients and enrolled over 160 to date, with top-line data expected as early as the first half of 2026 and an interim overall survival analysis planned after 144 events; positive results could support full regulatory approval and commercialization of Bria-IMT, potentially strengthening BriaCell’s position in the oncology immunotherapy market.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell’s Bria-IMT Shows Promising Results in Metastatic Breast Cancer Trials
Positive
Dec 10, 2025

BriaCell Therapeutics presented promising clinical data at the San Antonio Breast Cancer Symposium 2025, showcasing the potential of their Bria-IMT regimen in treating metastatic breast cancer. The Phase 3 study supports the use of biomarkers to identify patients who could benefit from the treatment, while Phase 2 data highlights significant long-term survival benefits. The findings suggest that Bria-IMT could provide a personalized therapeutic strategy for patients with limited treatment options, potentially impacting the company’s position in the oncology market.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell’s Phase 3 Study on Track for 2026 Data Readout
Positive
Dec 9, 2025

BriaCell Therapeutics has announced that its Phase 3 clinical study for its lead candidate, Bria-IMT, in combination with an immune checkpoint inhibitor, is progressing well with over 160 patients enrolled. The study, which targets metastatic breast cancer, is on track for a topline data readout in the first half of 2026, potentially leading to full approval and marketing authorization if results are positive.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell Unveils Promising Clinical Data at 2025 SABCS
Positive
Dec 2, 2025

BriaCell Therapeutics has announced the presentation of promising Phase 2 and Phase 3 clinical data at the 2025 San Antonio Breast Cancer Symposium. The data highlights robust survival benefits and the potential of specific biomarkers to predict clinical responses in metastatic breast cancer treatment, underscoring the company’s commitment to improving outcomes for patients with unmet medical needs.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Therapeutics to Present Promising Clinical Data at SABCS 2025
Positive
Nov 25, 2025

BriaCell Therapeutics announced positive results from its Phase 2 and Phase 3 clinical studies, which will be presented at the 2025 San Antonio Breast Cancer Symposium. The data highlights safety, efficacy, and biomarker findings, reinforcing confidence in their ongoing pivotal Phase 3 study for metastatic breast cancer. The Bria-IMT regimen has received Fast Track Designation from the US FDA, indicating its potential to address significant unmet medical needs in cancer treatment.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell and Receptor.AI Collaborate on AI-Driven Cancer Therapeutics
Positive
Nov 20, 2025

BriaCell Therapeutics has announced a collaboration between its subsidiary, BriaPro Therapeutics, and Receptor.AI to develop AI-driven small molecule cancer therapeutics. This partnership aims to expand BriaPro’s small-molecule pipeline and accelerate the development of next-generation therapeutics with improved efficacy and safety, marking a strategic expansion for BriaCell beyond cell-based immunotherapy into small-molecule discovery. The collaboration will leverage Receptor.AI’s platform to design highly selective anti-cancer kinase inhibitors, enhancing precision and confidence in oncology programs.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell to Present Key Clinical Data at SABCS 2025
Positive
Nov 18, 2025

BriaCell Therapeutics Corp. announced its selection to present key clinical data at the 2025 San Antonio Breast Cancer Symposium. The presentations will include updated biomarker data from its Phase 3 study and survival data from its Phase 2 study of Bria-IMT™ in metastatic breast cancer, highlighting the company’s progress in advancing cancer treatment options.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Unveils Promising Anti-Cancer Data for Bria-OTS+ Platform
Positive
Nov 7, 2025

BriaCell Therapeutics has presented promising preclinical data on its next-generation Bria-OTS+ platform at the SITC 2025 meeting, showcasing its rapid and durable anti-cancer activity. The platform, which activates both innate and adaptive immune responses, demonstrated increased tumor cell cytotoxicity in breast and prostate cancer models, suggesting broad applicability across multiple cancer types. These findings support the potential of Bria-OTS+ as a transformative cancer immunotherapy, with upcoming clinical trials planned for its lead candidates, Bria-BRES+ and Bria-PROS+.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell to Showcase Promising Cancer Immunotherapy Platform at SITC Meeting
Positive
Nov 4, 2025

BriaCell Therapeutics announced the presentation of their Bria-OTS+ platform at the upcoming Society for Immunotherapy of Cancer Annual Meeting. The platform, designed to enhance immune system engagement against cancer cells, has shown promising preclinical results in breast and prostate cancer models. The company is preparing for clinical trials of its lead candidates, Bria-BRES+ and Bria-PROS+, supported by a $2 million award from the National Cancer Institute, highlighting its potential to address unmet medical needs in cancer treatment.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 15, 2026