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BriaCell Therapeutics Corp (TSE:BCT)
TSX:BCT

BriaCell Therapeutics (BCT) AI Stock Analysis

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TSE:BCT

BriaCell Therapeutics

(TSX:BCT)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
C$15.00
▲(40.98% Upside)
The score is held down primarily by weak financial performance (no revenue, widening losses, and significant cash burn with likely ongoing financing needs). Technicals are mixed with some shorter-term strength but negative MACD and a price still far below the 200-day average. Valuation contributes limited support due to a negative P/E and no dividend yield.
Positive Factors
Pivotal Phase 3 progress
Advancing enrollment in a pivotal, randomized Phase 3 with >160 patients and an interim event trigger materially reduces binary development risk versus early-stage programs. Continued recruitment and a near-term readout (1H2026) sustain the company’s pathway to potential approval and partner interest.
Biomarker-driven clinical signals
Consistent Phase 2 survival signals and Phase 3 biomarker correlations (NLR, Th1 cytokine signatures) support patient selection and may enhance observed efficacy in registrational analyses. Durable biomarker strategies improve regulatory and commercial prospects by targeting responders and reducing uncertainty in pivotal outcomes.
Strategic R&D collaborations and pipeline expansion
Partnering with an AI-driven discovery firm to build a small-molecule franchise diversifies BriaCell beyond cell-based immunotherapies. This structural move can broaden addressable markets, accelerate lead discovery, and create longer-term value streams and licensing opportunities independent of a single vaccine program.
Negative Factors
Persistent cash burn
Sustained, large negative operating cash flow and growing net losses are durable constraints: they force repeated external financing, dilute shareholders, and can limit the company’s ability to independently fund late-stage activities or scale manufacturing without partnerships or capital raises.
Shrinking equity base and modest assets
A markedly reduced equity base and relatively small asset cushion leave limited financial flexibility. Even with no debt, accumulated losses and past dilution signal reliance on external capital and raise execution risk for capital-intensive pivotal and commercialization activities over the coming months.
Limited internal resources and scale
A very small headcount constrains in-house capabilities for complex activities—large-scale manufacturing, regulatory submissions, and commercialization. Reliance on external vendors and partners increases costs, coordination risk, and execution dependency during pivotal readouts and potential launch planning.

BriaCell Therapeutics (BCT) vs. iShares MSCI Canada ETF (EWC)

BriaCell Therapeutics Business Overview & Revenue Model

Company DescriptionBriaCell Therapeutics Corp., an immuno-oncology-focused biotechnology company, engages in developing immunotherapies for the management of cancer. Its lead drug candidate is Bria-IMT, a whole-cell cancer vaccine that is in Phase I/IIa clinical trials in combination with the immunotherapy development candidates retifanlimab. The company is also developing Bria-OTS, an off-the-shelf personalized immunotherapy for advanced breast cancer; and BriaDx, a diagnostic test that determines the patients' HLA types. It has a non-exclusive clinical trial collaboration with Incyte Corporation to evaluate the effects of combinations of novel clinical candidates; and a cooperative research and development agreement with the National Cancer Institute to conduct preclinical studies to develop and test Bria-OTS cellular immunotherapy as a treatment for cancer. BriaCell Therapeutics Corp. is based in West Vancouver, Canada.
How the Company Makes MoneyBriaCell Therapeutics makes money through a combination of research and development partnerships, grants, and potential future revenue from the commercialization of its cancer immunotherapy products. Revenue streams are primarily tied to the successful progression of its clinical trials and subsequent partnerships or licensing agreements with larger pharmaceutical companies. Additionally, BriaCell may receive funding from government and non-profit organizations interested in advancing cancer treatment research. The company's focus on developing proprietary immunotherapy solutions aims to establish a foothold in the oncology market, ultimately generating revenue through the sale and licensing of its therapies once they receive regulatory approval.

BriaCell Therapeutics Financial Statement Overview

Summary
BriaCell Therapeutics faces significant financial challenges with no revenue generation and consistent operational losses. The balance sheet shows a debt-free but weak equity position, posing financial stability risks. The company relies heavily on external financing due to negative operating and free cash flows.
Income Statement
8
Very Negative
BriaCell Therapeutics has no reported revenue over the periods analyzed, indicating a lack of commercial operations. The company consistently reports negative EBIT and EBITDA, reflecting ongoing operating losses. Net income remains negative, showing sustained unprofitability. Without revenue growth, the company's financial health is highly concerning.
Balance Sheet
52
Neutral
The company has managed to maintain a debt-free position throughout the periods, which is a positive aspect. However, the equity position has deteriorated significantly, with negative stockholders' equity in some periods. This indicates potential financial instability and risk of insolvency. The equity ratio is weak, reflecting limited asset financing through equity.
Cash Flow
10
Very Negative
BriaCell Therapeutics demonstrates negative operating and free cash flows, indicating cash burn without sufficient inflows from operations. This could lead to liquidity issues unless financing activities continue supporting operations. The company relies heavily on financing cash flows, underscoring a potential risk if external funding becomes scarce.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-147.89K-114.04K-20.49K-19.39K-19.44K
EBITDA-36.63M-45.91K-27.23M-34.05M-6.95M
Net Income-36.50M-6.62K-20.30M-11.58M-2.90M
Balance Sheet
Total Assets21.65M5.87M27.16M42.58M58.04M
Cash, Cash Equivalents and Short-Term Investments17.87M862.09K21.25M41.04M57.27M
Total Debt0.000.000.000.0025.99K
Total Liabilities4.32M8.56M30.94M32.25M782.24K
Stockholders Equity24.72M-2.38M-3.78M10.33M57.26M
Cash Flow
Free Cash Flow-28.17M-24.58M-23.74M-12.48M-7.75M
Operating Cash Flow-28.17M-24.13M-23.74M-12.48M-7.75M
Investing Cash Flow-7.65M-681.80K0.000.000.00
Financing Cash Flow45.45M4.42M3.95M-3.74M65.00M

BriaCell Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price10.64
Price Trends
50DMA
12.67
Negative
100DMA
13.53
Negative
200DMA
25.87
Negative
Market Momentum
MACD
-1.21
Positive
RSI
36.51
Neutral
STOCH
27.47
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:BCT, the sentiment is Negative. The current price of 10.64 is below the 20-day moving average (MA) of 10.67, below the 50-day MA of 12.67, and below the 200-day MA of 25.87, indicating a bearish trend. The MACD of -1.21 indicates Positive momentum. The RSI at 36.51 is Neutral, neither overbought nor oversold. The STOCH value of 27.47 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:BCT.

BriaCell Therapeutics Risk Analysis

BriaCell Therapeutics disclosed 50 risk factors in its most recent earnings report. BriaCell Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BriaCell Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
C$33.31M-15.19-8.01%-26.81%-161.24%
44
Neutral
C$12.70M-0.09-409.25%62.01%
43
Neutral
C$17.80M-3.9295.76%22.56%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:BCT
BriaCell Therapeutics
6.25
-76.25
-92.42%
TSE:DOSE
Rapid Dose Therapeutics Corp
0.14
-0.06
-30.00%
TSE:MBX
Microbix Biosystms
0.24
-0.20
-45.45%
TSE:RVX
Resverlogix
0.10
0.04
58.33%
TSE:GSD
Devonian Health Group
0.17
0.01
6.25%
TSE:TTI
Thiogenesis Therapeutics Corp
0.61
0.06
10.91%

BriaCell Therapeutics Corporate Events

Business Operations and StrategyDelistings and Listing ChangesPrivate Placements and Financing
BriaCell Raises $30 Million Through Public Offering of Units and Listed Warrants
Positive
Jan 14, 2026

BriaCell Therapeutics has priced a best-efforts public offering of 5,366,726 units, each comprising one common share or pre-funded warrant and one warrant, at $5.59 per unit for expected gross proceeds of approximately $30 million before fees and expenses. The warrants, exercisable at $6.93 per share for five years, have been approved for listing on the Nasdaq Capital Market under the symbol BCTXL starting January 14, 2026, with the offering slated to close on January 15, 2026, subject to customary conditions; BriaCell plans to use the net proceeds to support working capital, general corporate purposes and advancement of its business objectives, reinforcing its funding base as it progresses its immunotherapy pipeline.

The most recent analyst rating on (TSE:BCT) stock is a Sell with a C$9.50 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Reports Year-Long Complete Lung Metastasis Response in Breast Cancer Trial
Positive
Jan 13, 2026

BriaCell Therapeutics reported an 11‑month sustained complete resolution of a lung metastasis in a 78‑year‑old patient with hormone receptor–positive, HER2‑negative metastatic breast cancer treated with its personalized off‑the‑shelf immunotherapy Bria‑OTS in a Phase 1/2a study. The patient, who had failed multiple prior treatments, showed 100% disappearance of a lung tumor after four doses of Bria‑OTS monotherapy, with the response repeatedly confirmed over nearly a year, no treatment‑limiting toxicities observed, and stable disease at other evaluable sites; BriaCell has completed the Phase 1 dose escalation and is now advancing the Phase 2a dose‑expansion stage combining Bria‑OTS with an immune checkpoint inhibitor, a step that could strengthen its position in the metastatic breast cancer treatment landscape and underscore the platform’s potential safety and efficacy for patients with limited options.

The most recent analyst rating on (TSE:BCT) stock is a Sell with a C$9.50 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell’s Phase 3 Breast Cancer Trial Named a 2026 ‘Clinical Trial to Watch’ by Nature Medicine
Positive
Dec 18, 2025

BriaCell Therapeutics’ pivotal Phase 3 trial of its lead immunotherapy candidate Bria-IMT in metastatic breast cancer has been highlighted by Nature Medicine as one of the “clinical trials to watch in 2026,” underscoring rising scientific and clinical interest in the program. The BRIA-ABC study, which compares Bria-IMT plus an immune checkpoint inhibitor against physician’s choice therapy in a broad, real‑world metastatic breast cancer population, has screened more than 230 patients and enrolled over 160 to date, with top-line data expected as early as the first half of 2026 and an interim overall survival analysis planned after 144 events; positive results could support full regulatory approval and commercialization of Bria-IMT, potentially strengthening BriaCell’s position in the oncology immunotherapy market.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell’s Bria-IMT Shows Promising Results in Metastatic Breast Cancer Trials
Positive
Dec 10, 2025

BriaCell Therapeutics presented promising clinical data at the San Antonio Breast Cancer Symposium 2025, showcasing the potential of their Bria-IMT regimen in treating metastatic breast cancer. The Phase 3 study supports the use of biomarkers to identify patients who could benefit from the treatment, while Phase 2 data highlights significant long-term survival benefits. The findings suggest that Bria-IMT could provide a personalized therapeutic strategy for patients with limited treatment options, potentially impacting the company’s position in the oncology market.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell’s Phase 3 Study on Track for 2026 Data Readout
Positive
Dec 9, 2025

BriaCell Therapeutics has announced that its Phase 3 clinical study for its lead candidate, Bria-IMT, in combination with an immune checkpoint inhibitor, is progressing well with over 160 patients enrolled. The study, which targets metastatic breast cancer, is on track for a topline data readout in the first half of 2026, potentially leading to full approval and marketing authorization if results are positive.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell Unveils Promising Clinical Data at 2025 SABCS
Positive
Dec 2, 2025

BriaCell Therapeutics has announced the presentation of promising Phase 2 and Phase 3 clinical data at the 2025 San Antonio Breast Cancer Symposium. The data highlights robust survival benefits and the potential of specific biomarkers to predict clinical responses in metastatic breast cancer treatment, underscoring the company’s commitment to improving outcomes for patients with unmet medical needs.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Therapeutics to Present Promising Clinical Data at SABCS 2025
Positive
Nov 25, 2025

BriaCell Therapeutics announced positive results from its Phase 2 and Phase 3 clinical studies, which will be presented at the 2025 San Antonio Breast Cancer Symposium. The data highlights safety, efficacy, and biomarker findings, reinforcing confidence in their ongoing pivotal Phase 3 study for metastatic breast cancer. The Bria-IMT regimen has received Fast Track Designation from the US FDA, indicating its potential to address significant unmet medical needs in cancer treatment.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell and Receptor.AI Collaborate on AI-Driven Cancer Therapeutics
Positive
Nov 20, 2025

BriaCell Therapeutics has announced a collaboration between its subsidiary, BriaPro Therapeutics, and Receptor.AI to develop AI-driven small molecule cancer therapeutics. This partnership aims to expand BriaPro’s small-molecule pipeline and accelerate the development of next-generation therapeutics with improved efficacy and safety, marking a strategic expansion for BriaCell beyond cell-based immunotherapy into small-molecule discovery. The collaboration will leverage Receptor.AI’s platform to design highly selective anti-cancer kinase inhibitors, enhancing precision and confidence in oncology programs.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell to Present Key Clinical Data at SABCS 2025
Positive
Nov 18, 2025

BriaCell Therapeutics Corp. announced its selection to present key clinical data at the 2025 San Antonio Breast Cancer Symposium. The presentations will include updated biomarker data from its Phase 3 study and survival data from its Phase 2 study of Bria-IMT™ in metastatic breast cancer, highlighting the company’s progress in advancing cancer treatment options.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Unveils Promising Anti-Cancer Data for Bria-OTS+ Platform
Positive
Nov 7, 2025

BriaCell Therapeutics has presented promising preclinical data on its next-generation Bria-OTS+ platform at the SITC 2025 meeting, showcasing its rapid and durable anti-cancer activity. The platform, which activates both innate and adaptive immune responses, demonstrated increased tumor cell cytotoxicity in breast and prostate cancer models, suggesting broad applicability across multiple cancer types. These findings support the potential of Bria-OTS+ as a transformative cancer immunotherapy, with upcoming clinical trials planned for its lead candidates, Bria-BRES+ and Bria-PROS+.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell to Showcase Promising Cancer Immunotherapy Platform at SITC Meeting
Positive
Nov 4, 2025

BriaCell Therapeutics announced the presentation of their Bria-OTS+ platform at the upcoming Society for Immunotherapy of Cancer Annual Meeting. The platform, designed to enhance immune system engagement against cancer cells, has shown promising preclinical results in breast and prostate cancer models. The company is preparing for clinical trials of its lead candidates, Bria-BRES+ and Bria-PROS+, supported by a $2 million award from the National Cancer Institute, highlighting its potential to address unmet medical needs in cancer treatment.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell’s Phase 3 Study in Metastatic Breast Cancer Receives Positive DSMB Recommendation
Positive
Oct 22, 2025

BriaCell Therapeutics Corp. announced that the independent Data Safety Monitoring Board (DSMB) has given a positive recommendation for the continuation of its pivotal Phase 3 study of Bria-IMT plus immune checkpoint inhibitor in metastatic breast cancer patients. This marks the fourth consecutive positive DSMB recommendation, highlighting the favorable safety profile of the treatment. The study is conducted under the FDA Fast Track Designation, addressing the significant unmet medical need in metastatic breast cancer. The company’s leadership expressed confidence in the potential of Bria-IMT to transform cancer care for patients facing urgent medical needs.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Partners with MSK to Advance Cancer Immunotherapy
Positive
Oct 21, 2025

BriaCell Therapeutics has announced a collaboration with Memorial Sloan Kettering Cancer Center’s Therapeutics Accelerator Program to advance the clinical development of its Bria-OTS+ platform, which includes Bria-BRES+ for breast cancer. This partnership will provide BriaCell with access to MSK’s clinical and institutional expertise, facilitating the manufacturing, IND development, and clinical protocol support for a Phase 1 clinical trial. The collaboration aims to expedite the development of Bria-OTS+, potentially transforming cancer care and improving patient outcomes, particularly for those with metastatic breast cancer.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BriaCell Expands Phase 3 Study in Metastatic Breast Cancer
Positive
Oct 21, 2025

BriaCell Therapeutics has expanded its pivotal Phase 3 clinical study for metastatic breast cancer by adding key cancer centers such as Dartmouth Cancer Center, Cedars-Sinai Medical Center, and Winship Cancer Institute of Emory University. This expansion is expected to accelerate patient enrollment and potentially lead to full approval and marketing authorization for Bria-IMT, their lead clinical candidate, which has received FDA Fast Track designation. The study aims to compare the overall survival of patients treated with Bria-IMT and an immune checkpoint inhibitor against standard treatments, with interim data analysis planned once 144 patient events occur.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Business Operations and Strategy
BriaCell Reports Promising Phase 3 Data in Metastatic Breast Cancer Study
Positive
Oct 20, 2025

BriaCell Therapeutics has announced promising clinical biomarker data from its ongoing pivotal Phase 3 study of Bria-IMT combined with an immune checkpoint inhibitor in metastatic breast cancer. The data, presented at the ESMO Congress 2025, shows encouraging trends similar to those identified in the Phase 2 study, with no new safety concerns. The study’s positive interim results could lead to full approval and marketing authorization, potentially impacting treatment options for patients with limited choices.

The most recent analyst rating on (TSE:BCT) stock is a Buy with a C$40.00 price target. To see the full list of analyst forecasts on BriaCell Therapeutics stock, see the TSE:BCT Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 15, 2026