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Microbix Biosystms J (TSE:MBX)
TSX:MBX

Microbix Biosystms (MBX) AI Stock Analysis

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TSE:MBX

Microbix Biosystms

(TSX:MBX)

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Neutral 49 (OpenAI - 4o)
Rating:49Neutral
Price Target:
C$0.21
▼(-6.96% Downside)
Microbix Biosystems faces significant challenges in financial performance, with declining revenues and profitability issues. Technical analysis indicates bearish momentum, while valuation metrics are unattractive due to a negative P/E ratio. However, the earnings call provides some optimism with operational improvements and a strong financial position, aiming for recovery in fiscal 2026.
Positive Factors
Product Line Expansion
The introduction of the QUANTDx product line, which integrates earlier in assay development and sells at higher prices, positions Microbix to enhance its market presence and drive revenue growth, reflecting a strategic expansion of its product offerings.
Financial Stability
A strong balance sheet with a high current ratio and low debt-to-equity ratio provides Microbix with financial resilience, enabling it to withstand temporary setbacks and invest in growth opportunities.
Growth in Core Segments
The robust growth in the QAPs and antigen segments, despite setbacks from major clients, underscores the strength and potential of Microbix's core business areas, supporting long-term revenue expansion.
Negative Factors
Revenue Challenges
Significant revenue declines from key clients highlight customer concentration risks, which can impact financial performance and necessitate diversification to stabilize future earnings.
Margin Pressures
Persistent margin pressures from fixed costs and product mix challenges could constrain profitability, requiring strategic adjustments to improve cost efficiency and product offerings.
Market Uncertainty in China
The decline in demand for respiratory infection testing in China introduces uncertainty in a key market, potentially affecting future revenue streams and necessitating strategic market adjustments.

Microbix Biosystms (MBX) vs. iShares MSCI Canada ETF (EWC)

Microbix Biosystms Business Overview & Revenue Model

Company DescriptionMicrobix Biosystems Inc., a life science company, develops and commercializes proprietary biological and technological solutions for human health and wellbeing in North America, Europe, and internationally. It manufactures a range of critical biological materials for the diagnostics industry, notably antigens for immunoassays and its laboratory quality assessment and proficiency (QAPs) that support clinical lab proficiency testing, assay development and validation, or clinical lab workflows. The company also applies its biological expertise and infrastructure to develop other proprietary products, primarily viral transport medium (DxTM) to stabilize patient samples for lab-based testing and Kinlytic Urokinase, a biologic thrombolytic drug used to treat blood clots. It sells QAPs to lab accreditation organizations, diagnostics companies, and clinical labs through a network of regional distributors. Microbix Biosystems Inc. was founded in 1988 and is headquartered in Mississauga, Canada.
How the Company Makes MoneyMicrobix Biosystems generates revenue primarily through the sale of its proprietary products, which include antigens and quality control materials used in diagnostic testing. Their revenue model is based on direct sales to diagnostic laboratories, pharmaceutical companies, and other healthcare providers. Key revenue streams include the sale of viral and bacterial antigens, which are vital for various tests, as well as quality control products that ensure the reliability of laboratory results. Additionally, the company benefits from partnerships with other biotech firms and research institutions, which can lead to collaborative projects and increased sales opportunities. Significant contracts and collaborations with major players in the diagnostics industry further enhance its revenue potential, allowing Microbix to expand its market presence and leverage its product offerings effectively.

Microbix Biosystms Earnings Call Summary

Earnings Call Date:Dec 18, 2025
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Feb 12, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted substantial achievements in product development and operational efficiencies, positioning Microbix for future growth. However, the company faced significant revenue declines and profitability challenges in the second half of the year due to unexpected client losses and market conditions in China. Despite these setbacks, the company maintains a strong financial position and a positive outlook for recovery in fiscal 2026.
Q4-2025 Updates
Positive Updates
New Product Launches and Collaborations
Microbix announced several new product lines and collaborations, including the QUANTDx reference materials product line and partnerships with companies like SEKISUI and Seegene. These initiatives are expected to drive future growth and expand addressable markets.
Operational Efficiency Improvements
The company achieved significant improvements in batch yields and reduced failure rates, leading to lower costs and higher margins. Investments in automation and electronic quality management systems are expected to further enhance efficiencies.
Strong Financial Position
Microbix ended the fiscal year with a strong cash balance of over $12 million and access to additional funds through an undrawn mortgage facility and line of credit, totaling up to $24 million.
Support for Industry Needs
The company continued its support for public health with new products for emerging respiratory pandemics and collaborations for cervical cancer screening in multiple countries.
Negative Updates
Significant Revenue Decline
Overall revenues for the year decreased by 27%, impacted by the abrupt termination of a major client's project and reduced sales to China due to epidemiological reasons.
Profitability Challenges
The company experienced a profitable first half but faced a sizable loss in the second half of the fiscal year due to unexpected events and project cancellations.
Company Guidance
In the recent call, Microbix provided guidance that highlighted both challenges and opportunities for fiscal 2025 and the outlook for 2026. The company experienced a 27% decline in revenue, primarily due to a 100% reduction in Kinlytic revenues from $4.1 million in the previous year, as well as a slowdown in sales to China and the cancellation of a multi-hundred-million-dollar program with a major client. Despite these setbacks, other revenue areas increased by 12%. The gross margin decreased from 61% to 53%, attributed largely to the absence of Kinlytic sales. Operational improvements were noted, with batch yields increasing and failures decreasing significantly. For fiscal 2026, Microbix is targeting a 30% revenue growth from the low point of Q3, aiming to regain quarterly profitability by Q4. The company maintained a strong cash position of over $12 million and has access to up to $24 million in additional funds through undrawn credit facilities, ensuring financial resources to execute its plans without issuing new equity.

Microbix Biosystms Financial Statement Overview

Summary
Microbix Biosystems is facing challenges in revenue growth and profitability, as reflected in the income statement. The balance sheet remains stable with manageable leverage, but recent profitability issues are concerning. Cash flow analysis indicates liquidity challenges despite improvements in free cash flow growth. Overall, the company needs to address revenue and profitability pressures to improve its financial health.
Income Statement
45
Neutral
Microbix Biosystems has experienced a decline in revenue growth, with a negative growth rate of -12.06% in the latest year. The company also reported negative net income, resulting in a negative net profit margin. The gross profit margin remains relatively healthy at 53.01%, but the negative EBIT margin indicates operational challenges. Overall, the income statement reflects a company facing revenue and profitability pressures.
Balance Sheet
60
Neutral
The balance sheet shows a moderate debt-to-equity ratio of 0.24, indicating manageable leverage. However, the return on equity has turned negative, reflecting recent profitability issues. The equity ratio is stable, suggesting a solid capital structure. Overall, the balance sheet is stable but highlights concerns about recent profitability.
Cash Flow
50
Neutral
Cash flow analysis reveals a significant increase in free cash flow growth, but the company still reports negative free cash flow. The operating cash flow to net income ratio is negative, indicating cash flow challenges. Despite improvements in free cash flow growth, the cash flow statement suggests liquidity concerns.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue18.59M18.59M25.39M16.51M19.08M18.59M
Gross Profit9.85M9.85M15.39M7.48M11.12M11.04M
EBITDA428.23K428.23K6.21M1.96M3.73M5.66M
Net Income-2.25M-2.25M3.52M-39.48K1.79M1.63M
Balance Sheet
Total Assets37.41M37.41M38.10M35.65M33.15M28.83M
Cash, Cash Equivalents and Short-Term Investments12.11M12.11M12.96M11.61M13.49M9.99M
Total Debt6.77M6.77M6.40M6.65M5.82M7.74M
Total Liabilities9.62M9.62M9.80M11.03M8.21M10.27M
Stockholders Equity27.79M27.79M28.30M24.62M24.94M18.56M
Cash Flow
Free Cash Flow-877.58K-877.58K2.44M-2.11M1.44M804.20K
Operating Cash Flow-80.29K-80.29K4.35M-1.09M3.47M2.11M
Investing Cash Flow-797.30K-797.30K-1.91M-1.02M-2.03M-622.34K
Financing Cash Flow27.00K27.00K-1.08M229.21K2.06M8.41M

Microbix Biosystms Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.23
Price Trends
50DMA
0.24
Negative
100DMA
0.25
Negative
200DMA
0.29
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
44.47
Neutral
STOCH
50.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:MBX, the sentiment is Negative. The current price of 0.23 is below the 20-day moving average (MA) of 0.24, below the 50-day MA of 0.24, and below the 200-day MA of 0.29, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 44.47 is Neutral, neither overbought nor oversold. The STOCH value of 50.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:MBX.

Microbix Biosystms Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
C$31.97M-14.56-8.01%-26.81%-161.24%
43
Neutral
C$21.18M-0.16-409.25%62.01%
30
Underperform
C$42.69M-11.0272.92%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:MBX
Microbix Biosystms
0.23
-0.18
-43.90%
TSE:BCT
BriaCell Therapeutics
10.66
-106.34
-90.89%
TSE:RVX
Resverlogix
0.10
0.05
100.00%
TSE:GSD
Devonian Health Group
0.19
-0.01
-5.00%
TSE:DTC
Defence Therapeutics
0.78
0.14
21.88%
TSE:TTI
Thiogenesis Therapeutics Corp
0.55
-0.05
-8.33%

Microbix Biosystms Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Microbix Biosystems to Engage with Investors at Muskoka Capital Event
Positive
Sep 25, 2025

Microbix Biosystems Inc. announced its participation in the Muskoka Capital Event, where its CEO and COO will engage in one-on-one meetings with growth-oriented investors. This event is an opportunity for Microbix to enhance its visibility among investors and potentially secure financing and market support. The company’s participation underscores its proactive approach in engaging with the investment community to bolster its market presence and operational growth.

The most recent analyst rating on (TSE:MBX) stock is a Buy with a C$0.50 price target. To see the full list of analyst forecasts on Microbix Biosystms stock, see the TSE:MBX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Microbix and EMQN Launch EQA Program for Genetic Testing in Clopidogrel Dosing
Positive
Sep 23, 2025

Microbix Biosystems Inc. and EMQN CIC have launched a new external quality assessment (EQA) program to improve the accuracy of genetic testing for patients prescribed the anti-clotting drug Clopidogrel. This initiative aims to ensure that patients with gene variants affecting drug metabolism receive appropriate dosing, thereby reducing the risk of life-threatening bleeding or clots. The program utilizes Microbix’s quality assessment products to help laboratories maintain testing proficiency, ultimately aiding physicians and pharmacists in making informed prescription decisions. This collaboration marks Microbix’s second venture into supporting genetic test accuracy, complementing its established roles in infectious diseases and oncology.

The most recent analyst rating on (TSE:MBX) stock is a Buy with a C$0.50 price target. To see the full list of analyst forecasts on Microbix Biosystms stock, see the TSE:MBX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Microbix and Labquality Launch EQA Program for Accurate HPV-Related Cancer Diagnosis
Positive
Sep 17, 2025

Microbix Biosystems Inc. and Labquality Oy have launched a novel external quality assessment (EQA) program to help clinical laboratories accurately identify head and neck cancers associated with HPV. This initiative addresses a critical need in the diagnostics industry by providing proficiency testing for labs, using Microbix’s QAPs that emulate clinical specimens. The program aims to enhance diagnostic accuracy, reduce subjectivity in test interpretation, and prevent inappropriate treatment decisions, thereby supporting labs in achieving high-quality assurance standards.

The most recent analyst rating on (TSE:MBX) stock is a Buy with a C$0.50 price target. To see the full list of analyst forecasts on Microbix Biosystms stock, see the TSE:MBX Stock Forecast page.

Business Operations and Strategy
Microbix Hosts Ontario Minister to Showcase Biotech Innovations
Positive
Sep 3, 2025

Microbix Biosystems Inc. recently hosted Ontario’s Minister of Public and Business Service Delivery, Stephen Crawford, at its biotechnology manufacturing facilities in Mississauga. The visit highlighted the company’s role in advancing next-generation diagnostics to improve health outcomes and reduce healthcare costs. Supported by Ontario’s government with significant grant funding, Microbix has developed state-of-the-art manufacturing capabilities and world-leading healthcare products. The company’s operations contribute to economic growth and job creation in Ontario, emphasizing its commitment to innovation and quality in the life sciences sector.

The most recent analyst rating on (TSE:MBX) stock is a Buy with a C$0.50 price target. To see the full list of analyst forecasts on Microbix Biosystms stock, see the TSE:MBX Stock Forecast page.

Microbix Biosystems Navigates Challenges with Strategic Growth
Sep 1, 2025

Microbix Biosystems’ latest earnings call painted a picture of a challenging quarter, marked by significant revenue setbacks with two major clients. This led to the weakest performance in three years. Despite these hurdles, the company remains financially stable, with promising new product developments and ongoing progress in the Kinlytic project. The company is poised for future growth, building on strong financials and expanding product lines.

Business Operations and StrategyFinancial Disclosures
Microbix Biosystems Faces Revenue Decline Amid Market Challenges
Negative
Aug 14, 2025

Microbix Biosystems reported a challenging third quarter for fiscal 2025, with revenues falling to $3.5 million, a 31% decrease from the previous year, primarily due to reduced sales in China and the cancellation of test-development programs by a key customer. Despite a strong cash position, the company experienced a net loss of $1.64 million, driven by weaker gross margins and increased operating expenses. The year-to-date performance also saw a decline in revenues and margins, leading to an operating loss, although antigen sales showed some growth. The company’s financial ratios improved, indicating a strong liquidity position, but the outlook remains cautious due to ongoing challenges in key markets.

The most recent analyst rating on (TSE:MBX) stock is a Buy with a C$0.80 price target. To see the full list of analyst forecasts on Microbix Biosystms stock, see the TSE:MBX Stock Forecast page.

Financial Disclosures
Microbix Biosystems to Announce Q3 Fiscal 2025 Results
Neutral
Aug 7, 2025

Microbix Biosystems Inc. announced the upcoming release of its Q3 fiscal 2025 financial results, scheduled for August 14, 2025, followed by a webinar discussion with the company’s executives. This announcement is significant for stakeholders as it provides insights into the company’s financial health and operational performance, potentially impacting its market positioning and investor confidence.

The most recent analyst rating on (TSE:MBX) stock is a Buy with a C$0.80 price target. To see the full list of analyst forecasts on Microbix Biosystms stock, see the TSE:MBX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 22, 2025