Quarterly Revenue and EPS Growth
Q4 reported revenue rose 7% year-over-year to $12.21 billion and adjusted EPS increased 8% to $6.57 per share, driven by 3% organic growth, 2% from acquisitions, and a 2% FX tailwind.
Full-Year Financial Performance
FY2025 revenue grew 4% to $44.56 billion, adjusted operating income grew 4% to $10.11 billion, adjusted operating margin was 22.7%, and adjusted EPS grew 5% to $22.87.
Strong Operational Results and Margins
Q4 adjusted operating income was $2.88 billion (up 6%) with an adjusted operating margin of 23.6%; total-company adjusted gross margin was 41.8% in Q4 (41.7% for the full year).
Organic Growth Momentum
Q4 organic revenue growth was 3%; full-year organic growth was 2%. Management is guiding 2026 organic growth of 3%–4%, implying an acceleration from 2025.
Robust Free Cash Flow and Capital Deployment
Full-year operating cash flow was $7.82 billion and free cash flow was $6.34 billion after $1.48 billion of net capex. In 2025 the company deployed ~$16.5 billion (≈$13 billion M&A and $3.6 billion returned to shareholders).
Strategic M&A and Accretive Deal
Completed acquisitions include filtration & separation business and a Sanofi sterile fill-finish site; announced definitive agreement to acquire Clario (~$9 billion) — management expects the transaction to be accretive (Marc: ~+$0.45 adjusted EPS in first 12 months post-close; CFO: $0.20–$0.25 incremental adjusted EPS in 2026 if closed).
Segment Strength — Life Science & Biology/Biopharma
Life Science Solutions Q4 reported revenue +13% (organic +4%) with Q4 adjusted operating margin 35.5%; Biology Products & Biopharma Services Q4 reported revenue +7% (organic +5%) and Q4 adjusted operating income +12% (margin 14.5%).
Specialty Diagnostics Outperformance
Specialty Diagnostics Q4 reported revenue +5% (organic +3%); Q4 adjusted operating income increased 19% with margin at 26.6% — a 300 bps improvement versus prior-year quarter.
High-Impact Product Innovation
Notable 2025 launches and regulatory wins include Orbitrap Astro Zoom (mass spec), Thermo Scientific five-liter DynaDrive single-use bioreactor, CryoTom (cryo-EM), Helios MX-one FIB-SEM, Ion Torrent OncoMindDx FDA companion diagnostic approval, and Exens 510(k) clearance.
Guidance for 2026 Reflects Continued Growth
Management initiated 2026 guidance: revenue $46.3B–$47.2B (4%–6% reported growth) and adjusted EPS $24.22–$24.80 (6%–8% growth), assuming 3%–4% organic growth and ~50 bps adjusted operating margin expansion.