Restructuring ImpactThe company will restructure by reducing its workforce by 50% and eliminating all programs not related to THB335, creating near-term uncertainty.
Safety Profile ConcernsSafety profile concerns, including reductions in hemoglobin and neutrophils, likely limit the use of higher doses going forward.
Stock DowngradeAnalyst downgrades the stock to Equal-weight due to near-term uncertainty and lowers the price target from $20 to $5.