Solid Top-Line and Underlying Revenue Growth (Adjusted Basis)
Reported revenue of approximately $4.0 billion in Q1 2026 (down ~1% in local currency vs. Q1 2025). On an underlying like-for-like basis (excluding the Japan divestment and generic REVLIMID), management reports revenue growth of ~7%.
Strong Growth in Innovative Portfolio
Innovative products drove robust growth: AUSTEDO U.S. revenue $559M, up 41% year-over-year; UZEDY revenue up 62% to $63M; AJOVY grew 35% to $196M. Innovative portfolio now represents >20% of company revenue (up from ~9% in 2022).
Improving Margin Profile and Gross Margin Beat
Q1 non-GAAP gross margin of 52.9%, above management expectations. Company reiterates structural margin improvement trajectory with 2026 non-GAAP gross margin guidance of 54.5%–55.5% and an anticipated gross margin above 60% by 2030 as the portfolio shifts toward innovative, higher-margin products.
Profitability and Cash Flow Progress
Adjusted EBITDA reported at ~$1.1 billion (up ~2% YoY on a reported basis). Non-GAAP EPS was $0.53 (versus $0.52 a year ago). Free cash flow improved to $188 million in Q1 (from $107M last year), roughly a ~76% increase year-over-year for the quarter.
Balance Sheet and Leverage Progress
Net debt to EBITDA improved to ~2.42x at quarter-end. Management remains on track for a target net debt/EBITDA of <2.0x by 2027 and notes progress toward an investor-grade credit profile.
On Track with Transformation Savings
Pivot to Growth transformation programs targeting $700 million of savings by 2027. Management expects ~2/3 of the total savings to be realized by the end of 2026 and has recorded restructuring charges and cash outflows consistent with the program (e.g., ~$205M restructuring costs in 2025; additional $25M in Q1 2026).
Emalex Acquisition Aligned with Strategy
Agreement to acquire Emalex: $700M upfront cash plus up to $200M in commercial milestones. Ecopipam is described as first-in-class for Tourette syndrome, with an expected product gross margin profile of ~80%, regulatory filing expected H2 2026 and launch contribution beginning in 2027; acquisition intended to be accretive to non-GAAP EPS starting in 2028.
Biosimilars and Generics Positioning
Biosimilar build-out: 11 biosimilars currently on the market, 4 additional expected that cover ~$16B of originator sales through 2027, and a further 9 planned covering ~$58B thereafter — demonstrating growing contribution from higher-value generics/biosimilars.
Robust R&D/Pipeline Milestone Cadence
Multiple near-term pipeline catalysts: seven milestone readouts this year (including duvakitug maintenance, anti–IL-15 vitiligo readout in H1, celiac readout in H2, DARI Phase III events, emrusolmin futility analysis and PD-1–IL-2 data). Management estimates the pipeline opportunities could amount to >$10B peak sales.