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Sangamo Therapeutics
(OTC:SGMOQ)
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Rating:45Neutral
Price Target:
$0.12
▲(91.67% Upside)
Action:Reiterated
Date:08/12/26
The score is held down primarily by very weak financial performance (declining revenue, large ongoing losses, heavy cash burn, and negative equity) and severe distress-related corporate events (Chapter 11 and delisting/OTC transition). Technical indicators show some short-term momentum improvement, and the earnings call provided meaningful regulatory/clinical progress, but these positives are outweighed by funding uncertainty and restructuring risk.
Positive Factors
Regulatory clarity and BLA progress
FDA agreement on an accelerated approval endpoint and a rolling BLA that is materially advanced reduces regulatory uncertainty for ST‑920. This durable regulatory clarity shortens potential approval path, strengthens the program's de‑risking profile and improves the prospect of partner interest if funding is secured.
Negative Factors
Chapter 11 and asset sale process
Active Chapter 11 proceedings and an approved auction process create existential risk for equity and can force asset sales or reorganization. This structural event can terminate or materially change R&D programs, impair long‑term continuity, and shift priority toward creditor outcomes over scientific execution.
Read all positive and negative factors
Positive Factors
Negative Factors
Regulatory clarity and BLA progress
FDA agreement on an accelerated approval endpoint and a rolling BLA that is materially advanced reduces regulatory uncertainty for ST‑920. This durable regulatory clarity shortens potential approval path, strengthens the program's de‑risking profile and improves the prospect of partner interest if funding is secured.
Read all positive factors
Sangamo Therapeutics (SGMOQ) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$60.07M
Dividend YieldN/A
Average Volume (3M)7.65M
Price to Earnings (P/E)―
Beta (1Y)2.34
Revenue Growth-45.80%
EPS Growth-0.16%
CountryUS
Employees142
SectorGeneral
Sector StrengthN/A
IndustryBiotechnology
Share Statistics
EPS (TTM)-0.38
Shares Outstanding414,288,850
10 Day Avg. Volume4,237,466
30 Day Avg. Volume7,646,780
Financial Highlights & Ratios
PEG Ratio0.09
Price to Book (P/B)-8.25
Price to Sales (P/S)2.98
P/FCF Ratio-1.21
Enterprise Value/Market Cap<0.01
Enterprise Value/Revenue<0.01
Enterprise Value/Gross Profit<0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price Target
$2.00Price Target Upside3233.33% Upside
Rating ConsensusHold
Number of Analyst Covering1
EPS Forecast (FY)-0.3
Revenue Forecast (FY)$9.90M
Sangamo Therapeutics Business Overview & Revenue Model
Company Description
Sangamo Therapeutics (SGMO) is a clinical-stage biotechnology company focused on developing genomic medicine therapies. The company’s work centers on gene regulation and gene editing approaches, including zinc finger protein (ZFP) technology, to c...
How the Company Makes Money
Sangamo Therapeutics primarily generates revenue through collaboration and licensing arrangements rather than product sales, as product revenue is null (no commercial products). Under these partnerships, Sangamo can earn (1) upfront payments when ...
Sangamo Therapeutics Earnings Call Summary
Earnings Call Date:May 14, 2026
(Q1-2026)
| % Change Since: |
Next Earnings Date:Oct 29, 2026
Earnings Call Sentiment Neutral
The call highlights meaningful clinical and regulatory progress for ST-920 (rolling BLA, FDA affirmation of 2-year confirmatory endpoint, durable long-term patient data) and continued advancement across neurology programs and platform technologies. However, material near-term risks center on capital availability and a NASDAQ delisting determination that forced a transition to the OTCQB market. Progress on regulatory and scientific fronts is balanced by significant financing and market-listing challenges that could impact execution and timing.Positive Updates
BLA Rolling Submission Progress for ST-920 (Fabry)
First 2 modules of the rolling BLA for ST-920 submitted; company states the rolling submission is ~3/5 complete and anticipates completing the BLA submission as early as this summer, subject to adequate funding. FDA affirmed accelerated approval pathway using mean annualized eGFR slope at 52 weeks across all 32 dosed patients.
Negative Updates
NASDAQ Delisting Determination and Market Transition
Received a delisting determination from NASDAQ due to noncompliance with minimum bid requirements; common stock transitioned to trading on the OTCQB Venture Market under the same ticker (SGMO); company intends to appeal at a June hearing.
Read all updates
Q1-2026 Updates
Positive
Negative
BLA Rolling Submission Progress for ST-920 (Fabry)
First 2 modules of the rolling BLA for ST-920 submitted; company states the rolling submission is ~3/5 complete and anticipates completing the BLA submission as early as this summer, subject to adequate funding. FDA affirmed accelerated approval pathway using mean annualized eGFR slope at 52 weeks across all 32 dosed patients.
Read all positive updates
Company Guidance
Sangamo said the rolling BLA for ST‑920 is in progress with the first two modules submitted, the clinical module (1‑year data) already filed, management characterizing the filing as roughly 3/5 complete and anticipating BLA completion “as early as this summer” subject to securing additional funding; the FDA agreed accelerated approval can be based on mean annualized eGFR slope at 52 weeks across all 32 dosed patients, affirmed no additional confirmatory trial is required, and indicated 104‑week (2‑year) data across those 32 patients may be used for full approval (the last patient reached the 2‑year time point around April). Management also highlighted durability and safety — four patients beyond five years with supraphysiological alpha‑Gal and 17 patients off ERT (some >3 years) — and operational progress in neurology with six sites activated for the Phase I/II STAND (ST‑503), GLP toxicology for ST‑506 completed with analysis ongoing, and MHRA alignment on key matters.Sangamo Therapeutics Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
24
Negative
Cash Flow
15
Very Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 34.56M | 39.55M | 57.80M | 176.23M | 111.30M | 110.70M |
| Gross Profit | 34.56M | 31.95M | 57.80M | 176.23M | 99.19M | 110.70M |
| EBITDA | -117.46M | -115.90M | -89.09M | -96.80M | -179.74M | -160.35M |
| Net Income | -123.33M | -122.93M | -97.94M | -257.83M | -192.28M | -178.29M |
Balance Sheet | ||||||
| Total Assets | 59.97M | 59.74M | 101.64M | 165.32M | 562.51M | 721.92M |
| Cash, Cash Equivalents and Short-Term Investments | 27.59M | 20.95M | 41.92M | 81.00M | 277.63M | 376.55M |
| Total Debt | 19.33M | 26.80M | 30.57M | 38.10M | 43.11M | 48.08M |
| Total Liabilities | 78.92M | 74.01M | 78.86M | 82.43M | 267.55M | 346.58M |
| Stockholders Equity | -18.95M | -14.27M | 22.77M | 82.89M | 294.96M | 375.34M |
Cash Flow | ||||||
| Free Cash Flow | -90.46M | -97.31M | -67.41M | -246.00M | -243.80M | -256.53M |
| Operating Cash Flow | -90.34M | -97.21M | -67.14M | -224.84M | -223.63M | -233.25M |
| Investing Cash Flow | -115.00K | -102.00K | 37.52M | 153.53M | 59.28M | 248.20M |
| Financing Cash Flow | 89.31M | 70.75M | 28.38M | 14.59M | 84.66M | 32.86M |
Sangamo Therapeutics Risk Analysis
Sangamo Therapeutics disclosed 62 risk factors in its most recent earnings report. Sangamo Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Sangamo Therapeutics Peers Comparison
UnderperformOutperform
Sector (55)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
55 Neutral | $6.65B | 3.83 | -15.92% | 6.20% | 10.91% | 7.18% | |
49 Neutral | $167.62M | -1.20 | -100.13% | ― | 12.96% | 12.51% | |
48 Neutral | $120.08M | -2.84 | -38.80% | ― | -100.00% | -392.92% | |
45 Neutral | $60.07M | -0.20 | 6686.36% | ― | -45.80% | -0.16% | |
43 Neutral | $454.92M | -1.45 | -131.58% | ― | ― | 22.16% | |
42 Neutral | $71.10M | -1.30 | -2748.16% | ― | ― | 43.68% |
* General Sector Average
SGMOQ
Sangamo Therapeutics
0.15
-0.39
-71.67%
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Sangamo Therapeutics Corporate Events
Business Operations and StrategyDelistings and Listing ChangesLegal Proceedings
Sangamo Therapeutics Advances Bankruptcy Asset Sale Process
Negative
Jul 20, 2026
Sangamo Therapeutics, Inc. filed for Chapter 11 bankruptcy protection on June 23, 2026, in the U.S. Bankruptcy Court for the District of Delaware and continues to operate as a debtor-in-possession. On July 14, 2026, the court approved auction and ...
Delistings and Listing ChangesLegal Proceedings
Sangamo Shares Shift to OTC Market Amid Bankruptcy
Negative
Jul 1, 2026
On June 24, 2026, Sangamo Therapeutics’ common stock began trading on the OTCID Basic Market under the symbol SGMOQ, reflecting the company’s transition into over-the-counter trading after its voluntary Chapter 11 bankruptcy filing. Th...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.