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Serina Therapeutics (SER)
:SER
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Serina Therapeutics (SER) AI Stock Analysis

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SER

Serina Therapeutics

(SER)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$2.00
▼(-2.44% Downside)
Action:Reiterated
Date:05/15/26
Overall score is held back primarily by weak financial performance (minimal revenue, large losses, and significant cash burn) and bearish technical trends (below major moving averages with negative MACD). Offsetting these, corporate events are a near-term positive due to added funding runway and governance/leadership actions, but valuation support is limited given ongoing losses and no dividend.
Positive Factors
Proprietary polymer drug-delivery platform
Serina’s POZ polymer-conjugate platform targets long-acting, controlled-release formulations, a durable competitive edge for chronic CNS indications. A platform approach enables multiple programs, potential licensing/partnerships, and recurring revenue paths if clinical success translates to approved products.
Negative Factors
Minimal and flat revenue base
Revenue is negligible and not growing, meaning the business cannot self-fund operations or demonstrate commercial traction. This structural lack of revenue forces ongoing dependence on external capital and raises execution risk if clinical progress slows or market conditions limit financing options.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary polymer drug-delivery platform
Serina’s POZ polymer-conjugate platform targets long-acting, controlled-release formulations, a durable competitive edge for chronic CNS indications. A platform approach enables multiple programs, potential licensing/partnerships, and recurring revenue paths if clinical success translates to approved products.
Read all positive factors

Serina Therapeutics (SER) vs. SPDR S&P 500 ETF (SPY)

Serina Therapeutics Business Overview & Revenue Model

Company Description
Serina Therapeutics, Inc., a biotechnology company, develops drugs to treat neurological diseases and pain. Its lead product candidate is SER 252, a POZ conjugate for the treatment of Parkinson's disease. The company also develops SER 227 for long...
How the Company Makes Money
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Serina Therapeutics Financial Statement Overview

Summary
Early-stage profile with minimal TTM revenue (~$0.13M) alongside large and persistent losses (TTM net loss ~$21.3M) and heavy cash burn (TTM operating/free cash flow about -$18.2M). Balance sheet leverage is low (debt ~$0.16M vs equity ~$17.6M), but ongoing losses and historical volatility (including past negative equity) remain key risks.
Income Statement
18
Very Negative
Balance Sheet
55
Neutral
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Mar 2023Dec 2021
Income Statement
Total Revenue130.00K0.0056.00K3.15M500.00K3.46M
Gross Profit96.00K0.00-138.00K3.06M500.00K-333.84K
EBITDA-20.37M-18.91M-10.49M5.92M-2.60M-1.23M
Net Income-21.27M-19.18M-11.14M5.27M-2.68M-1.26M
Balance Sheet
Total Assets27.30M6.95M6.72M8.97M3.24M3.15M
Cash, Cash Equivalents and Short-Term Investments24.53M3.06M3.67M7.62M645.00K584.00K
Total Debt3.17M196.00K268.00K3.44M18.12M13.20M
Total Liabilities9.67M6.99M6.22M41.26M20.56M15.03M
Stockholders Equity17.63M-37.00K641.00K4.11M-17.21M-11.83M
Cash Flow
Free Cash Flow-18.24M-17.95M-17.16M-2.98M-2.09M-2.36M
Operating Cash Flow-18.20M-17.95M-17.14M-2.48M-2.08M-2.25M
Investing Cash Flow-84.00K-59.00K-22.00K-504.00K980.94K823.32K
Financing Cash Flow38.55M17.41M13.21M10.07M1.31M1.08M

Serina Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2.05
Price Trends
50DMA
1.98
Negative
100DMA
2.07
Negative
200DMA
3.23
Negative
Market Momentum
MACD
>-0.01
Negative
RSI
50.57
Neutral
STOCH
67.95
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SER, the sentiment is Neutral. The current price of 2.05 is above the 20-day moving average (MA) of 1.76, above the 50-day MA of 1.98, and below the 200-day MA of 3.23, indicating a neutral trend. The MACD of >-0.01 indicates Negative momentum. The RSI at 50.57 is Neutral, neither overbought nor oversold. The STOCH value of 67.95 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for SER.

Serina Therapeutics Risk Analysis

Serina Therapeutics disclosed 69 risk factors in its most recent earnings report. Serina Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Serina Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$29.25M-1.04-1259.21%
47
Neutral
$27.91M-0.53-70.57%-100.00%21.30%
46
Neutral
$89.44M-0.98<0.01%86.28%
42
Neutral
$28.69M-0.28763.31%-51.03%-35.20%
41
Neutral
$29.87M-0.54-217.27%-74.39%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SER
Serina Therapeutics
1.84
-4.06
-68.81%
OTLK
Outlook Therapeutics
0.73
-1.04
-58.76%
SKYE
Skye Bioscience
0.78
-1.47
-65.40%
CELU
Celularity
1.01
-1.23
-54.91%
BRNS
Barinthus Biotherapeutics
0.68
-0.39
-36.45%
JUNS
Jupiter Neurosciences, Inc.
0.26
-0.56
-68.78%

Serina Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board Changes
Serina Therapeutics Updates Executive Leadership and Governance Structure
Positive
Apr 21, 2026
On April 20, 2026, Serina Therapeutics (AL), Inc., a wholly owned subsidiary of Serina Therapeutics, Inc., promoted Srini Tenjarla, Ph.D., from Senior Vice President of CMC and Formulation to Chief Technology Officer and increased his annual base ...
Business Operations and StrategyExecutive/Board ChangesPrivate Placements and Financing
Serina Therapeutics Announces Premium Private Placement Financing
Positive
Mar 23, 2026
On March 17, 2026, Serina Therapeutics entered into a securities purchase agreement for a private placement of common stock, pre-funded warrants and redeemable warrants led by board director Greg Bailey, with an initial $15 million tranche that in...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 15, 2026