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Serina Therapeutics (SER)
:SER

Serina Therapeutics (SER) AI Stock Analysis

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SER

Serina Therapeutics

(SER)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$2.00
▼(-3.85% Downside)
Action:ReiteratedDate:03/31/26
The score is primarily held down by weak financial performance (minimal/volatile revenue, large losses, and sustained cash burn) and a bearish long-term technical trend (price below key moving averages). Corporate events modestly offset this via improved financing runway, but listing-compliance risk and a negative/less-informative P/E keep overall risk elevated.
Positive Factors
Platform & Focus
Serina’s polymer conjugate platform targets long-acting, controlled-release formulations for CNS and chronic diseases. That platform-level approach creates durable technical differentiation and multiple application pathways, increasing partnership and licensing optionality beyond any single asset.
Negative Factors
Sustained Cash Burn
Persistent negative operating and free cash flow at ~-$18M annually exhausts resources absent recurring revenue, forcing repeated external financings. This structural burn increases dilution risk, compresses management focus on financing over development, and raises the probability of capital-access constraints within months.
Read all positive and negative factors
Positive Factors
Negative Factors
Platform & Focus
Serina’s polymer conjugate platform targets long-acting, controlled-release formulations for CNS and chronic diseases. That platform-level approach creates durable technical differentiation and multiple application pathways, increasing partnership and licensing optionality beyond any single asset.
Read all positive factors

Serina Therapeutics (SER) vs. SPDR S&P 500 ETF (SPY)

Serina Therapeutics Business Overview & Revenue Model

Company Description
Serina Therapeutics, Inc., a biotechnology company, develops drugs to treat neurological diseases and pain. Its lead product candidate is SER 252, a POZ conjugate for the treatment of Parkinson's disease. The company also develops SER 227 for long...
How the Company Makes Money
null...

Serina Therapeutics Financial Statement Overview

Summary
Financial profile is weak: revenues are very small and volatile, losses are large (deeply negative net margins in 2024–2025), and operating/free cash flow show sustained heavy burn (about -$18.0M FCF in 2025). Low absolute debt helps, but the move to slightly negative shareholders’ equity in 2025 increases balance-sheet risk and reliance on external funding.
Income Statement
18
Very Negative
Balance Sheet
22
Negative
Cash Flow
15
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Mar 2023Dec 2021
Income Statement
Total Revenue130.00K56.00K3.15M500.00K3.46M
Gross Profit45.00K-138.00K3.06M500.00K-333.84K
EBITDA-24.02M-10.49M5.92M-2.60M-1.23M
Net Income-19.18M-11.14M5.27M-2.68M-1.26M
Balance Sheet
Total Assets6.95M6.72M8.97M3.24M3.15M
Cash, Cash Equivalents and Short-Term Investments3.06M3.67M7.62M645.00K584.00K
Total Debt196.00K268.00K3.44M18.12M13.20M
Total Liabilities6.99M6.22M41.26M20.56M15.03M
Stockholders Equity-37.00K641.00K4.11M-17.21M-11.83M
Cash Flow
Free Cash Flow-17.95M-17.16M-2.98M-2.09M-2.36M
Operating Cash Flow-17.95M-17.14M-2.48M-2.08M-2.25M
Investing Cash Flow-59.00K-22.00K-504.00K980.94K823.32K
Financing Cash Flow17.41M13.21M10.07M1.31M1.08M

Serina Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.08
Price Trends
50DMA
2.07
Negative
100DMA
2.57
Negative
200DMA
3.90
Negative
Market Momentum
MACD
0.04
Positive
RSI
48.89
Neutral
STOCH
25.08
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SER, the sentiment is Negative. The current price of 2.08 is above the 20-day moving average (MA) of 2.07, above the 50-day MA of 2.07, and below the 200-day MA of 3.90, indicating a bearish trend. The MACD of 0.04 indicates Positive momentum. The RSI at 48.89 is Neutral, neither overbought nor oversold. The STOCH value of 25.08 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SER.

Serina Therapeutics Risk Analysis

Serina Therapeutics disclosed 78 risk factors in its most recent earnings report. Serina Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Serina Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
$23.57M-0.53-143.59%-53.18%
44
Neutral
$40.08M-0.59763.31%-15.81%-113.06%
44
Neutral
$22.10M-0.43-70.57%-100.00%-26.30%
43
Neutral
$25.61M-1.46-1259.21%
40
Underperform
$22.28M-1.03293.07%86.28%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SER
Serina Therapeutics
2.02
-3.02
-59.92%
OTLK
Outlook Therapeutics
0.25
-0.95
-79.17%
SKYE
Skye Bioscience
0.71
-0.64
-47.63%
CELU
Celularity
1.37
-0.20
-12.74%
BRNS
Barinthus Biotherapeutics
0.59
-0.10
-14.14%
JUNS
Jupiter Neurosciences, Inc.
0.37
-0.19
-33.57%

Serina Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board ChangesPrivate Placements and Financing
Serina Therapeutics Announces Premium Private Placement Financing
Positive
Mar 23, 2026
On March 17, 2026, Serina Therapeutics entered into a securities purchase agreement for a private placement of common stock, pre-funded warrants and redeemable warrants led by board director Greg Bailey, with an initial $15 million tranche that in...
Delistings and Listing ChangesFinancial DisclosuresRegulatory Filings and Compliance
Serina Therapeutics Faces NYSE American Compliance Deficiency Notice
Negative
Jan 15, 2026
On January 9, 2026, Serina Therapeutics received a deficiency notification from NYSE American stating the company is not in compliance with the exchange’s minimum stockholders’ equity requirements, after reporting equity of $1.6 millio...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 31, 2026