Global Sales Revenue Growth
Revenue from global sales of IMCIVREE was $37.7 million in the first quarter of 2025, with the number of patients on reimbursed therapy increasing 14% globally during the quarter.
Phase 3 Trial Results for Setmelanotide
Phase 3 study showed a 16.5% reduction in BMI in the setmelanotide cohort compared to a 3.3% increase in BMI in the placebo group, for a placebo-adjusted difference of 19.8%.
Demand for IMCIVREE
Continued increasing demand for IMCIVREE, with a consistent number of new prescriptions received over the past several quarters, resulting in ongoing growth in patients on reimbursed therapy.
International Expansion
Steady global growth in the number of patients on paid therapy, with notable contributions from France, Germany, and Italy.
Financial Position
Rhythm remains well-capitalized with a projected cash runway into 2027.