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Prophase Labs (PRPH)
OTHER OTC:PRPH
US Market

Prophase Labs (PRPH) AI Stock Analysis

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PRPH

Prophase Labs

(OTC:PRPH)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
$0.20
▲(8.33% Upside)
Overall score reflects weak financial performance (sharp revenue decline, negative margins, and negative cash flows) and strongly bearish technicals (well below moving averages with negative MACD). Offsetting factors are limited to mixed but potentially impactful earnings-call catalysts (collections and product partnering) and corporate actions that include both upside (strategic transaction potential) and significant risks (delisting/OTC and dilution-related volatility).
Positive Factors
Commercial-stage diagnostic asset (BE‑Smart)
A published, clinic-ready diagnostic that has drawn partnership and acquisition interest represents a durable commercial and strategic asset. If commercialized, BE‑Smart addresses a large $7–14B targeted market the company cited, offering long‑term revenue potential and partner leverage for scale.
Material receivables collection opportunity
A credible collections program targeting at least $50M net would materially improve liquidity and the balance sheet if realized. This structural cash inflow could reduce reliance on dilutive financings, fund operations or R&D, and materially lower short‑term solvency risk over the coming months.
Convertible debt conversions reduced indebtedness
Significant conversion of convertible debt into equity lowers cash interest and near‑term debt servicing needs, improving structural leverage metrics. That deleveraging enhances financing flexibility, reduces default risk, and supports longer‑term strategic initiatives if further capital actions remain disciplined.
Negative Factors
Sharp revenue decline and negative margins
A steep, persistent top‑line decline paired with deep negative margins signals structural demand or commercialization weakness. Sustained losses erode equity, limit internal funding for R&D and go‑to‑market, and make the business dependent on external capital or non‑organic fixes over the medium term.
Elevated leverage on the balance sheet
High leverage relative to equity increases fixed obligations and refinancing risk, especially given negative earnings. Elevated debt constrains strategic flexibility, raises vulnerability to interest or covenant shocks, and can impede investment in commercialization or R&D until deleveraging occurs.
Delisting and move to OTC undermines liquidity and visibility
Loss of Nasdaq listing and transition to OTC is a structural governance and liquidity setback that reduces institutional access and investor visibility. This impairs the company's ability to raise non‑dilutive capital, negotiate favorable partner terms, and may elevate long‑term financing and execution costs.

Prophase Labs (PRPH) vs. SPDR S&P 500 ETF (SPY)

Prophase Labs Business Overview & Revenue Model

Company DescriptionProPhase Labs, Inc. engages in the research, development, manufacture, distribution, marketing, and sale of over the counter (OTC) consumer healthcare products and dietary supplements in the United States. The company operates in two segments, Diagnostic Services and Consumer Products. It offers a range of OTC dietary supplements, including Legendz XL for male sexual health; and Triple Edge XL, an energy and stamina booster. The company also provides contract manufacturing services, such as product development, pre-commercialization, production, warehousing, and distribution; SARS-CoV-2 (COVID-19) and COVID-19 viral mutation polymerase chain reaction tests through saliva and nasal swab methods; and other respiratory pathogen panel molecular testing services, as well as personal genomics products and services. It serves national chain drug, internet-based, and various regional retailers. The company was formerly known as The Quigley Corporation. ProPhase Labs, Inc. was founded in 1989 and is headquartered in Garden City, New York.
How the Company Makes MoneyProphase Labs generates revenue through the commercialization of its pharmaceutical products and therapies. Key revenue streams include direct sales of its proprietary antiviral treatments, licensing agreements for its intellectual property, and collaborations with other pharmaceutical companies for research and development initiatives. Additionally, the company may receive funding through grants and partnerships with healthcare organizations that support innovative medical research. The strength of its revenue model is bolstered by strategic alliances with research institutions and industry partners, which enhance its product development capabilities and market reach.

Prophase Labs Earnings Call Summary

Earnings Call Date:Nov 19, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Apr 01, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted several promising developments, such as the Crown Medical collections, potential partnerships for the esophageal cancer test, and a turnaround in the Nebula Genomics business. However, these positives were counterbalanced by significant challenges, including financial constraints, a declining stock price, and the need for a reverse stock split to maintain Nasdaq compliance. The company is actively pursuing strategic initiatives to address these issues and improve shareholder value.
Q3-2025 Updates
Positive Updates
Crown Medical Collections Initiative
Crown Medical has been appointed special counsel to collect $150 million in uncollected COVID testing claims. They expect to collect at least $50 million net, which could significantly improve the company's financial situation.
B Smart Esophageal Cancer Test
The esophageal cancer test is considered one of the best diagnostic tests for one of the deadliest cancers. Now that it's been published in a major journal, it has attracted interest from various companies looking to partner or acquire.
Nebula Genomics Business Turnaround
The Nebula Genomics business has been restructured to become primarily direct-to-consumer, with a subscription model that is profitable on a pro forma basis.
Potential Strategic Initiatives
The company is exploring multiple strategic initiatives, including potential M&A deals and partnerships, which could significantly enhance shareholder value. They are also considering a crypto treasury strategy once cash flow improves.
Negative Updates
Stock Price and Market Cap Concerns
The company is facing a low market cap of around $12 million and a declining share price, which is affecting investor confidence and creating pressure to maintain Nasdaq compliance.
Delayed Cash Flow from Crown Medical
The process of getting court approval for Crown Medical to act as special counsel took longer than expected, delaying the anticipated cash flow from collections.
Financial Constraints and Share Dilution
The company has been operating under financial constraints, leading to discussions on share dilution and the need to potentially execute a reverse stock split to maintain Nasdaq compliance.
Company Guidance
During the ProPhase Labs, Inc.'s third-quarter 2025 earnings call, Chairman and CEO Ted Karkus provided several metrics and strategic insights. He emphasized the importance of shareholder voting on a critical proxy, which could impact strategic initiatives. The company is targeting collections of around $150 million in uncollected COVID testing claims, with expectations to net at least $50 million after discounts and fees. Karkus also discussed the potential of the BSmart esophageal cancer test, estimating a target market of $7-14 billion, and highlighted Nebula Genomics' restructuring towards profitability. ProPhase Labs' current market cap stands at approximately $12 million, with 46.1 million shares outstanding. Karkus addressed the possibility of a reverse stock split to maintain Nasdaq compliance, aiming to capitalize on the company's undervalued stock and significant asset potential.

Prophase Labs Financial Statement Overview

Summary
Prophase Labs is facing significant financial challenges, with declining revenues and negative profitability metrics. The high leverage and negative cash flows further exacerbate the company's financial instability. While there is some positive movement in free cash flow growth, the overall financial health remains weak.
Income Statement
Prophase Labs has experienced significant revenue decline in the TTM period, with a negative revenue growth rate of -67.75%. The company also faces negative profit margins, including a net profit margin of -38.72% and an EBIT margin of -22.35%. These figures indicate substantial profitability challenges and declining sales, which are concerning for the company's financial health.
Balance Sheet
The balance sheet shows a high debt-to-equity ratio of 1.12 in the TTM period, indicating significant leverage. The return on equity is negative, reflecting the company's inability to generate profits from shareholders' equity. However, the equity ratio remains stable, suggesting that a reasonable portion of assets is financed by equity.
Cash Flow
The cash flow statement reveals a substantial increase in free cash flow growth rate of 287.09% in the TTM period, which is a positive sign. However, both operating and free cash flows are negative, and the operating cash flow to net income ratio is also negative, indicating cash flow challenges despite the growth in free cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.08M6.77M44.38M122.65M79.04M14.51M
Gross Profit2.06M-150.00K16.24M70.65M32.81M4.61M
EBITDA-24.81M-32.34M-14.83M28.73M11.39M-1.49M
Net Income-41.70M-53.36M-16.78M18.46M6.27M-2.13M
Balance Sheet
Total Assets65.70M63.20M91.93M87.65M89.30M31.41M
Cash, Cash Equivalents and Short-Term Investments405.00K678.00K4.74M17.44M17.51M8.46M
Total Debt7.68M24.57M18.46M6.96M14.90M14.72M
Total Liabilities58.84M55.85M42.54M24.02M30.67M20.85M
Stockholders Equity6.86M7.35M49.38M63.63M58.63M10.56M
Cash Flow
Free Cash Flow-22.75M-18.44M-14.50M24.63M-17.85M-4.28M
Operating Cash Flow-22.99M-17.54M-11.35M28.55M-13.62M-2.59M
Investing Cash Flow-40.00K2.42M-1.37M-2.08M-19.67M-1.02M
Financing Cash Flow9.66M14.19M5.76M-26.02M35.13M9.99M

Prophase Labs Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.18
Price Trends
50DMA
1.74
Negative
100DMA
3.04
Negative
200DMA
3.29
Negative
Market Momentum
MACD
-0.46
Negative
RSI
16.18
Positive
STOCH
9.03
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PRPH, the sentiment is Negative. The current price of 0.18 is below the 20-day moving average (MA) of 0.74, below the 50-day MA of 1.74, and below the 200-day MA of 3.29, indicating a bearish trend. The MACD of -0.46 indicates Negative momentum. The RSI at 16.18 is Positive, neither overbought nor oversold. The STOCH value of 9.03 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PRPH.

Prophase Labs Risk Analysis

Prophase Labs disclosed 63 risk factors in its most recent earnings report. Prophase Labs reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Prophase Labs Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$23.84M78.930.27%75.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$10.87M-0.28-44.42%-1.50%80.17%
49
Neutral
$27.10M-0.87-50.23%-15.61%-68.96%
45
Neutral
$7.56M-1.83-93.87%-0.74%81.49%
44
Neutral
$7.62M-0.22-37.38%-22.60%53.82%
41
Neutral
$1.23M-0.01
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PRPH
Prophase Labs
0.20
-6.29
-96.86%
TXMD
TherapeuticsMD
2.06
1.02
98.08%
AYTU
Aytu BioScience
2.66
0.97
57.40%
YCBD
cbdMD
1.08
-2.82
-72.31%
IMCC
IM Cannabis Corp
1.44
-0.88
-37.93%
FLGC
Flora Growth
7.06
-29.17
-80.51%

Prophase Labs Corporate Events

Business Operations and StrategyDelistings and Listing ChangesPrivate Placements and FinancingStock Split
ProPhase Labs Updates Shareholders Amid Volatility and OTC Move
Negative
Jan 9, 2026

On January 5, 2026, Prophase Labs issued an update to shareholders explaining that recent volatility in its common stock was largely driven by technical factors tied to its capital structure, including an accelerated conversion and resale of most of its outstanding convertible debt, a 1-for-10 reverse stock split completed on December 5, 2025, and the company’s move from the Nasdaq Capital Market to trading on the OTC market as of January 5, 2026, following its delisting from Nasdaq. The company reported that more than $3.3 million of an initial $3.8 million in convertible debt principal had been converted into equity, leaving less than $500,000 unconverted, and noted that these conversions, executed at a floor price well above the recent market price, increased the share count but reduced indebtedness dollar-for-dollar and strengthened the balance sheet, even as the influx of new shares contributed to short-term selling pressure and potentially reduced liquidity and institutional interest; management stressed that it views the intrinsic value of its subsidiaries and assets, as well as its long-term strategy and growth prospects, as unchanged by these mechanics and is focused on stabilizing its capital structure, completing near-term financing initiatives, and advancing its core operations, while cautioning that the stock may remain volatile.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.24 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Executive/Board Changes
ProPhase Labs Announces Immediate Resignation of Board Member
Neutral
Jan 9, 2026

On January 5, 2026, ProPhase Labs, Inc. announced that board member Warren Hirsch resigned from the company’s Board of Directors, effective immediately. The company stated that his departure was not due to any disagreement over operations, policies, or practices, and publicly expressed appreciation for his service and contributions during his tenure, suggesting an orderly and non-contentious transition at the board level.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.24 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyDelistings and Listing ChangesRegulatory Filings and Compliance
ProPhase Labs faces Nasdaq delisting, plans appeal, OTC move
Negative
Jan 2, 2026

On December 29, 2025, ProPhase Labs, Inc. disclosed that it had failed to regain compliance with Nasdaq’s $1.00 minimum bid price requirement by the end of its second 180-day grace period on December 22, 2025, triggering a determination by Nasdaq staff to delist the company from the Nasdaq Capital Market. Nasdaq has notified ProPhase that trading in its common stock is scheduled to be suspended at the opening of business on January 5, 2026, after which a delisting filing will be made with the U.S. securities regulator; in response, the company plans to appeal the decision to a Nasdaq Hearings Panel and is simultaneously seeking to have its shares quoted on the OTC Markets, a move that could affect liquidity and visibility for shareholders while leaving the company’s longer-term listing status uncertain.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.44 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyM&A Transactions
ProPhase Labs Announces Proposed Reverse Merger with ABL
Positive
Dec 19, 2025

ProPhase Labs, Inc. announced that it has entered into a non-binding letter of intent for a proposed reverse merger with Advanced Biological Laboratories S.A., a European biotechnology company, under which ABL would become the majority owner of the combined entity. The contemplated transaction, if completed, would significantly reshape ProPhase’s ownership structure and strategic direction by aligning it more closely with ABL’s biotech focus, with potential implications for shareholders and the company’s positioning in the broader healthcare and diagnostics market.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.13 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Delistings and Listing ChangesStock Split
Prophase Labs Implements Reverse Stock Split
Neutral
Dec 12, 2025

On November 30, 2025, Prophase Labs‘ stockholders approved a reverse stock split of its common stock at a ratio of one share for every ten shares, effective December 2, 2025. This move was aimed at increasing the per-share trading price to meet NASDAQ’s continued listing requirements. The reverse stock split did not alter stockholders’ percentage ownership, except for cash adjustments for fractional shares, and the company’s common stock continues to trade under the symbol ‘PRPH’.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.13 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyShareholder MeetingsStock Split
Prophase Labs Approves Strategic Proposals at Special Meeting
Positive
Nov 26, 2025

On November 24, 2025, ProPhase Labs, Inc. conducted a Special Meeting of Stockholders where six proposals were presented and approved. The proposals included acquiring digital assets, creating a new class of digital treasury shares, issuing digital tokens, and authorizing stock splits. Proposal 4, concerning stock splits, notably met the approval requirements for charter amendments under Delaware law, indicating strong shareholder support and potential strategic shifts for the company.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and FinancingRegulatory Filings and Compliance
Prophase Labs Secures Forbearance Agreement with Avtech Capital
Neutral
Nov 25, 2025

On November 21, 2025, ProPhase Labs, Inc. received confirmation from Avtech Capital, LLC to continue its forbearance under an existing equipment lease, with a new payment schedule starting November 28, 2025. This arrangement ensures the company can bring its lease current without affecting its operations, liquidity, or financial reporting, as confirmed by their recent Form 10-Q.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Legal Proceedings
Prophase Labs Faces Unsealed Civil Action Disclosure
Neutral
Nov 25, 2025

On November 21, 2025, ProPhase Labs, Inc. disclosed that a civil action filed against it in 2023 had been unsealed by court order on November 4, 2025. The unsealing is a procedural step under the False Claims Act, and the company was unaware of the action until November 19, 2025. ProPhase Labs has not been served with the complaint and has received no indication of governmental intervention. The company denies any wrongdoing, maintains its compliance standards, and intends to defend itself vigorously. It also notes that a separate private dispute with Dr. Hennrick was resolved in April 2024. The company does not expect the unsealed matter to impact its operations.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyLegal ProceedingsM&A TransactionsProduct-Related Announcements
Prophase Labs Unveils Strategic Initiatives and Partnerships
Positive
Nov 19, 2025

On November 19, 2025, ProPhase Labs announced its strategic initiatives, including M&A discussions and the commercialization of the BE-Smart™ Esophageal Cancer Test following a landmark study. The company is also pursuing a $50 million collection initiative through Crown Medical, which has been appointed as Special Counsel to expedite litigation against insurance carriers. These efforts aim to unlock significant value for ProPhase, which it believes is not reflected in its current share price.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
ProPhase Labs Signs Sales Agreement with WestPark Capital
Neutral
Oct 15, 2025

On October 9, 2025, ProPhase Labs, Inc. entered into an At-the-Market Sales Agreement with WestPark Capital, Inc., allowing the company to offer and sell shares of its common stock through the agent. This agreement, underpinned by the company’s effective registration statement and related prospectus, provides ProPhase Labs with flexibility in its stock offerings, potentially impacting its market presence and financial strategy. The agreement includes customary provisions and allows for termination by either party, reflecting a strategic move to manage its capital and shareholder interests.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 10, 2026