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Prophase Labs (PRPH)
NASDAQ:PRPH
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Prophase Labs (PRPH) AI Stock Analysis

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PRPH

Prophase Labs

(NASDAQ:PRPH)

Rating:47Neutral
Price Target:
$0.50
▲(51.52% Upside)
Prophase Labs' overall stock score is primarily impacted by its financial performance, which is currently weak due to declining revenues and negative profitability. Technical analysis indicates a bearish trend with no strong momentum. Valuation metrics are unattractive with a negative P/E ratio. The earnings call provides some optimism with potential future growth initiatives, but ongoing risks remain significant.

Prophase Labs (PRPH) vs. SPDR S&P 500 ETF (SPY)

Prophase Labs Business Overview & Revenue Model

Company DescriptionProPhase Labs, Inc. engages in the research, development, manufacture, distribution, marketing, and sale of over the counter (OTC) consumer healthcare products and dietary supplements in the United States. The company operates in two segments, Diagnostic Services and Consumer Products. It offers a range of OTC dietary supplements, including Legendz XL for male sexual health; and Triple Edge XL, an energy and stamina booster. The company also provides contract manufacturing services, such as product development, pre-commercialization, production, warehousing, and distribution; SARS-CoV-2 (COVID-19) and COVID-19 viral mutation polymerase chain reaction tests through saliva and nasal swab methods; and other respiratory pathogen panel molecular testing services, as well as personal genomics products and services. It serves national chain drug, internet-based, and various regional retailers. The company was formerly known as The Quigley Corporation. ProPhase Labs, Inc. was founded in 1989 and is headquartered in Garden City, New York.
How the Company Makes MoneyProphase Labs generates revenue through several key streams, including the sale of its proprietary diagnostic products, therapeutic solutions, and any associated licensing agreements. The company may also form strategic partnerships with other biotech firms, healthcare providers, or research institutions to co-develop products or services, which can lead to additional revenue through collaboration fees or shared profits. Additionally, Prophase Labs may receive funding from government grants or private investments aimed at supporting research and development initiatives, further contributing to its overall earnings.

Prophase Labs Earnings Call Summary

Earnings Call Date:Aug 13, 2025
(Q1-2025)
|
% Change Since: -5.71%|
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Neutral
ProPhase Labs is navigating through financial challenges by implementing cost reductions and restructuring efforts. The company is focused on upcoming liquidity events, including the potential sale of Nebula Genomics and significant collections from Crown Medical, which are expected to improve its financial position. However, the shortfall in COVID testing revenue and challenges in maintaining NASDAQ compliance present ongoing risks.
Q1-2025 Updates
Positive Updates
Pharmaloz Manufacturing Sale
ProPhase Labs sold the Pharmaloz manufacturing facility for $23 million, which significantly increased their shareholders' equity and cleaned up the balance sheet.
Cost Reduction and Restructuring
ProPhase Labs has reduced its headcount from 96 employees to 25 and shut down the genomics laboratory, resulting in significant overhead cost reductions.
Potential Sale of Nebula Genomics
ProPhase Labs is exploring strategic alternatives for Nebula Genomics, including a potential sale, which could significantly increase the company's cash flow and assets.
BE-Smart Esophageal Cancer Test
The BE-Smart Esophageal Cancer Test has multibillion-dollar potential, targeting approximately 7 million endoscopies per year in the US. It aims to enhance endoscopy accuracy and is expected to be commercialized later in 2025.
Crown Medical Collections
Crown Medical is actively working on collecting outstanding COVID testing receivables, with potential significant cash inflows expected in the next few months.
Debt Financing and Liquidity Strategy
ProPhase Labs is focused on debt financing rather than issuing shares, anticipating significant liquidity events in the second half of 2025.
NASDAQ Listing Compliance
The company anticipates receiving a 6-month extension to maintain NASDAQ listing compliance, meeting all criteria except stock price.
Negative Updates
COVID Testing Revenue Shortfall
ProPhase Labs faced a significant shortfall in COVID testing revenue due to government and insurance reimbursement issues, impacting the company's cash flow.
Stock Price Below NASDAQ Requirements
ProPhase Labs' stock has been trading below $1 for five months, which poses a risk to NASDAQ listing compliance, though an extension is anticipated.
Deferred Executive Compensation
Company executives, including the CEO, have deferred a significant portion of their compensation until liquidity events occur, reflecting financial strain.
Uncertainty in Collection Timelines
There is uncertainty regarding the exact timeline for collecting outstanding COVID testing receivables from insurance companies.
Company Guidance
In the call discussing ProPhase Labs' first quarter 2025 results, CEO Ted Karkus provided guidance highlighting several key metrics and expectations for the company. He emphasized the anticipated commercialization of the BE-Smart Esophageal Cancer Test later in the year, targeting approximately 7 million endoscopies annually in the U.S., with a potential reimbursement of $1,000 to $2,000 per test. Karkus also discussed the sale of Nebula Genomics, stating that the company's genomic data set is equivalent to over 150 million ancestry tests, and potential acquisition interest could align with the company's market cap. Additionally, he mentioned plans to address liquidity through debt financing, with expected substantial cash flow from Crown Medical collections and the sale of Nebula Genomics in the latter half of 2025. The company also addressed NASDAQ compliance, expecting a six-month extension to meet listing requirements, and outlined cost-cutting measures, including reducing headcount from 96 to 25 employees since December.

Prophase Labs Financial Statement Overview

Summary
Prophase Labs is facing severe financial challenges, including a drastic decline in revenue, negative profit margins, high leverage, and negative cash flows. These factors indicate significant operational inefficiencies and liquidity constraints.
Income Statement
30
Negative
Prophase Labs has seen a significant decline in revenue, with a TTM revenue of $4.57M, down from $67.7M in the previous year, representing a drastic revenue contraction. The gross profit margin has also deteriorated from a negative gross profit previously to $0.81M. The net profit margin is negative due to the substantial net losses reported, indicating profitability challenges. EBIT and EBITDA margins are deeply negative, reflecting operational inefficiencies or high operational costs.
Balance Sheet
45
Neutral
The company exhibits a high debt-to-equity ratio of approximately 0.93 in the TTM period, suggesting a relatively high level of leverage. Stockholders' equity has increased over the year, providing some financial stability. However, the equity ratio has decreased, indicating a decline in the proportion of assets financed by equity. High leverage may pose financial risks in a volatile market environment.
Cash Flow
35
Negative
Prophase Labs faces negative free cash flow and operating cash flow, reflecting potential liquidity issues. The free cash flow to net income ratio is not feasible due to negative values, indicating cash flow challenges. The operating cash flow to net income ratio is also negative, highlighting ineffective cash generation from operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue3.34M6.77M44.38M122.65M79.04M14.51M
Gross Profit2.02M-150.00K16.24M70.65M32.81M4.61M
EBITDA-26.18M-32.34M-14.83M28.73M11.39M-1.49M
Net Income-41.45M-53.36M-16.78M18.46M6.27M-2.13M
Balance Sheet
Total Assets42.04M63.20M91.93M87.65M89.30M31.41M
Cash, Cash Equivalents and Short-Term Investments171.00K678.00K4.74M17.44M17.26M8.46M
Total Debt5.54M24.57M21.38M6.96M14.90M14.72M
Total Liabilities30.61M55.85M42.54M24.02M30.67M20.85M
Stockholders Equity11.44M7.35M49.38M63.63M58.63M10.56M
Cash Flow
Free Cash Flow-6.03M-18.44M-14.50M24.63M-17.85M-4.28M
Operating Cash Flow-6.09M-17.54M-11.35M28.55M-13.62M-2.59M
Investing Cash Flow783.00K2.42M-1.37M-2.08M-19.67M-1.02M
Financing Cash Flow8.79M14.19M5.76M-26.02M35.13M9.99M

Prophase Labs Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.33
Price Trends
50DMA
0.37
Negative
100DMA
0.36
Negative
200DMA
0.54
Negative
Market Momentum
MACD
-0.02
Positive
RSI
45.77
Neutral
STOCH
35.94
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PRPH, the sentiment is Negative. The current price of 0.33 is below the 20-day moving average (MA) of 0.36, below the 50-day MA of 0.37, and below the 200-day MA of 0.54, indicating a bearish trend. The MACD of -0.02 indicates Positive momentum. The RSI at 45.77 is Neutral, neither overbought nor oversold. The STOCH value of 35.94 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PRPH.

Prophase Labs Risk Analysis

Prophase Labs disclosed 63 risk factors in its most recent earnings report. Prophase Labs reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Prophase Labs Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$23.28M-58.30%
51
Neutral
$7.44B-0.20-46.00%2.27%22.80%-2.27%
50
Neutral
$9.43M-531.54%11.20%63.16%
47
Neutral
$14.71M-58.71%-79.66%-141.87%
47
Neutral
$12.79M-1.98%156.93%92.75%
41
Neutral
$8.81M-106.83%-95.85%49.94%
$275.14M-58.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PRPH
Prophase Labs
0.33
-2.17
-86.80%
TLPH
Talphera
0.43
-0.46
-51.69%
TXMD
TherapeuticsMD
1.15
-0.51
-30.72%
SISI
Shineco
6.11
-617.17
-99.02%
COSM
Cosmos Holdings
0.88
-0.28
-24.14%
BFRI
Biofrontera
0.97
-0.39
-28.68%

Prophase Labs Corporate Events

Product-Related AnnouncementsBusiness Operations and StrategyFinancial Disclosures
ProPhase Labs Achieves Key U.S. Patent for Test
Positive
Aug 13, 2025

ProPhase Labs reported significant financial and operational improvements for the first half of 2025, including a strengthened equity position and reduced liabilities. The company achieved a key U.S. patent for its BE-Smart™ Esophageal Adenocarcinoma Risk Assessment test, positioning it for faster market entry. Additionally, ProPhase streamlined its operations, reduced costs, and improved margins, setting a path for future growth. The company is also exploring a strategic treasury initiative involving digital assets to complement its core businesses.

Executive/Board ChangesBusiness Operations and StrategyRegulatory Filings and Compliance
ProPhase Labs Appoints New Fractional CFO
Neutral
Aug 6, 2025

ProPhase Labs, Inc. announced the resignation of its Chief Operating Officer, Stu Hollenshead, effective July 31, 2025, who will transition to a marketing consultant role. The company is searching for a successor, with interim duties managed by the executive team. Additionally, ProPhase Labs appointed Steven M. Plumb as its fractional Chief Financial Officer on August 6, 2025. Plumb, a seasoned financial executive, will provide operational advice and oversee SEC filings, while CEO Ted Karkus remains the principal financial officer.

Shareholder MeetingsBusiness Operations and StrategyRegulatory Filings and Compliance
Prophase Labs Files Proxy to Increase Shares
Positive
Jul 29, 2025

On July 29, 2025, ProPhase Labs announced the filing of a Preliminary Proxy Statement with the SEC, aiming to increase authorized shares to 1 billion. This strategic move is intended to attract high-value transactions and industry-leading participants in the crypto treasury space, enhancing the company’s growth potential and flexibility. The Board of Directors has recommended shareholders vote in favor of these proposals at the Special Meeting on August 29, 2025, to strengthen ProPhase Labs’ ability to innovate and create shareholder value.

Private Placements and Financing
Prophase Labs Secures $3M Investment Through Private Placement
Positive
Jul 28, 2025

On July 22, 2025, ProPhase Labs entered into a Securities Purchase Agreement with two investors for a private placement of senior secured convertible notes and warrants, amounting to a principal cash investment of $3,000,000. The transaction is designed to protect long-term shareholder value by preventing excessive dilution and downward price spirals, while also granting investors a first priority security interest in the company’s assets. The net proceeds will be used for working capital, general corporate purposes, and debt repayment. The agreement includes provisions to ensure the company retains control over its assets unless a default occurs.

Executive/Board ChangesShareholder MeetingsRegulatory Filings and Compliance
Prophase Labs Holds Annual Stockholders Meeting
Neutral
Jul 25, 2025

On July 18, 2025, ProPhase Labs, Inc. held its Annual Meeting of Stockholders where several key decisions were made. The company’s stockholders elected board members, ratified the appointment of independent auditors, approved executive compensation, and decided on the frequency of future advisory votes on executive compensation. Notably, Ms. Carolina Abenante was appointed to the Audit Committee, leading to the company’s compliance with Nasdaq Listing Rules.

Private Placements and FinancingBusiness Operations and Strategy
Prophase Labs Secures $3 Million in Private Financing
Positive
Jul 23, 2025

On July 23, 2025, ProPhase Labs announced the closing of a $3 million private placement financing with two investors involving senior secured convertible notes and warrants to purchase common stock. The funds will be used for working capital, corporate purposes, and debt repayment, while supporting potential liquidity events and crypto strategies.

M&A TransactionsBusiness Operations and Strategy
Prophase Labs Explores Reverse Merger with Digital Asset Firm
Neutral
Jul 21, 2025

On July 18, 2025, ProPhase Labs’ Board of Directors authorized the exploration of a potential reverse merger with a digital asset-focused company to enhance shareholder value and market positioning. This strategic initiative includes a crypto treasury strategy and aims to identify growth opportunities at the intersection of life sciences and financial innovation, although no binding agreement has been made yet.

Executive/Board ChangesRegulatory Filings and Compliance
ProPhase Labs Regains Nasdaq Compliance with New Appointment
Positive
Jul 1, 2025

ProPhase Labs, Inc. resolved a compliance issue with Nasdaq’s audit committee requirements after a vacancy was created by the resignation of Eleanor McBrier. The company appointed Carolina Abenante to the Board and Audit Committee, regaining compliance with Nasdaq rules as confirmed by Nasdaq on June 25, 2025.

Private Placements and FinancingBusiness Operations and Strategy
Prophase Labs Secures $1M in New Loan Agreements
Neutral
Jun 26, 2025

On June 22, 2025, ProPhase Labs entered into two identical loan agreements totaling $500,000 each with its CEO, Ted Karkus, and an unaffiliated investor. The loans, which include a 20% original issue discount and a 10% annual interest rate, are secured by the company but subordinate to other lenders up to $6 million. Additionally, the company issued 500,000 unvested warrants for common stock, contingent on future shareholder approval. This move, approved by the Audit Committee, reflects ProPhase Labs’ strategic financial maneuvering to bolster its capital structure.

Delistings and Listing ChangesRegulatory Filings and Compliance
ProPhase Labs Granted Nasdaq Extension for Compliance
Neutral
Jun 26, 2025

On June 26, 2025, ProPhase Labs announced that it received a 180-day extension from Nasdaq to meet the minimum bid price requirement of $1.00 per share, following an initial period ending on June 24, 2025. This extension allows the company until December 22, 2025, to regain compliance, failing which its stock may face delisting. The company is actively monitoring its stock price and exploring options to meet the requirement, although there is no assurance of compliance within the extended period. This development does not impact ProPhase Labs’ business operations or reporting obligations.

Executive/Board Changes
Prophase Labs Appoints Carolina Abenante as Director
Neutral
Jun 25, 2025

On June 20, 2025, ProPhase Labs, Inc. appointed Carolina Abenante as an independent director to fill a vacancy on its Board of Directors. She was also appointed to the Nominating and Corporate Governance Committee and as Chair of the Compensation Committee, with her term set to expire at the 2025 annual meeting of stockholders. The Board intends to nominate her for re-election and plans to appoint her to the Audit Committee following the annual meeting. Ms. Abenante meets the independence and financial literacy requirements set by Nasdaq and the SEC.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 15, 2025