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Prophase Labs (PRPH)
:PRPH

Prophase Labs (PRPH) AI Stock Analysis

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PRPH

Prophase Labs

(NASDAQ:PRPH)

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Underperform 39 (OpenAI - 4o)
Rating:39Underperform
Price Target:
$0.08
▼(-53.33% Downside)
Prophase Labs' overall stock score is primarily impacted by its weak financial performance and poor valuation metrics. The technical analysis also suggests a bearish trend. While there are potential positive developments from corporate events and strategic initiatives, these are not enough to offset the current financial and market challenges.
Positive Factors
Strategic Partnerships
Engaging in strategic partnerships and commercializing innovative tests can enhance market position and drive long-term revenue growth.
Reverse Merger with ABL
The reverse merger with ABL could significantly reshape ProPhase's strategic direction, aligning it with biotech focus and enhancing competitive positioning.
Free Cash Flow Growth
Strong free cash flow growth indicates improved cash generation ability, which can support strategic investments and financial stability.
Negative Factors
Declining Revenue
Declining revenue poses a challenge to sustaining operations and investments, potentially impacting long-term growth and market competitiveness.
High Leverage
High leverage can strain financial resources, limiting flexibility and increasing risk, particularly in volatile market conditions.
Negative Profit Margins
Negative profit margins indicate operational inefficiencies and profitability challenges, which can hinder long-term financial health and shareholder returns.

Prophase Labs (PRPH) vs. SPDR S&P 500 ETF (SPY)

Prophase Labs Business Overview & Revenue Model

Company DescriptionProphase Labs, Inc. (PRPH) is a biotechnology company focused on developing and commercializing innovative therapies for infectious diseases and other medical conditions. The company operates primarily in the healthcare and life sciences sectors, with a strong emphasis on antiviral and therapeutic solutions. Prophase Labs is known for its proprietary product offerings, including treatments for respiratory viruses and other infectious agents, leveraging cutting-edge research and development in the field of virology.
How the Company Makes MoneyProphase Labs generates revenue through the commercialization of its pharmaceutical products and therapies. Key revenue streams include direct sales of its proprietary antiviral treatments, licensing agreements for its intellectual property, and collaborations with other pharmaceutical companies for research and development initiatives. Additionally, the company may receive funding through grants and partnerships with healthcare organizations that support innovative medical research. The strength of its revenue model is bolstered by strategic alliances with research institutions and industry partners, which enhance its product development capabilities and market reach.

Prophase Labs Earnings Call Summary

Earnings Call Date:Nov 19, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Apr 01, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted several promising developments, such as the Crown Medical collections, potential partnerships for the esophageal cancer test, and a turnaround in the Nebula Genomics business. However, these positives were counterbalanced by significant challenges, including financial constraints, a declining stock price, and the need for a reverse stock split to maintain Nasdaq compliance. The company is actively pursuing strategic initiatives to address these issues and improve shareholder value.
Q3-2025 Updates
Positive Updates
Crown Medical Collections Initiative
Crown Medical has been appointed special counsel to collect $150 million in uncollected COVID testing claims. They expect to collect at least $50 million net, which could significantly improve the company's financial situation.
B Smart Esophageal Cancer Test
The esophageal cancer test is considered one of the best diagnostic tests for one of the deadliest cancers. Now that it's been published in a major journal, it has attracted interest from various companies looking to partner or acquire.
Nebula Genomics Business Turnaround
The Nebula Genomics business has been restructured to become primarily direct-to-consumer, with a subscription model that is profitable on a pro forma basis.
Potential Strategic Initiatives
The company is exploring multiple strategic initiatives, including potential M&A deals and partnerships, which could significantly enhance shareholder value. They are also considering a crypto treasury strategy once cash flow improves.
Negative Updates
Stock Price and Market Cap Concerns
The company is facing a low market cap of around $12 million and a declining share price, which is affecting investor confidence and creating pressure to maintain Nasdaq compliance.
Delayed Cash Flow from Crown Medical
The process of getting court approval for Crown Medical to act as special counsel took longer than expected, delaying the anticipated cash flow from collections.
Financial Constraints and Share Dilution
The company has been operating under financial constraints, leading to discussions on share dilution and the need to potentially execute a reverse stock split to maintain Nasdaq compliance.
Company Guidance
During the ProPhase Labs, Inc.'s third-quarter 2025 earnings call, Chairman and CEO Ted Karkus provided several metrics and strategic insights. He emphasized the importance of shareholder voting on a critical proxy, which could impact strategic initiatives. The company is targeting collections of around $150 million in uncollected COVID testing claims, with expectations to net at least $50 million after discounts and fees. Karkus also discussed the potential of the BSmart esophageal cancer test, estimating a target market of $7-14 billion, and highlighted Nebula Genomics' restructuring towards profitability. ProPhase Labs' current market cap stands at approximately $12 million, with 46.1 million shares outstanding. Karkus addressed the possibility of a reverse stock split to maintain Nasdaq compliance, aiming to capitalize on the company's undervalued stock and significant asset potential.

Prophase Labs Financial Statement Overview

Summary
Prophase Labs is facing significant financial challenges, with declining revenues and negative profitability metrics. The high leverage and negative cash flows further exacerbate the company's financial instability. While there is some positive movement in free cash flow growth, the overall financial health remains weak, and the company needs to address these issues to improve its financial standing.
Income Statement
35
Negative
Prophase Labs has experienced significant revenue decline in the TTM period, with a negative revenue growth rate of -67.75%. The company also faces negative profit margins, including a net profit margin of -38.72% and an EBIT margin of -22.35%. These figures indicate substantial profitability challenges and declining sales, which are concerning for the company's financial health.
Balance Sheet
40
Negative
The balance sheet shows a high debt-to-equity ratio of 1.12 in the TTM period, indicating significant leverage. The return on equity is negative, reflecting the company's inability to generate profits from shareholders' equity. However, the equity ratio remains stable, suggesting that a reasonable portion of assets is financed by equity.
Cash Flow
45
Neutral
The cash flow statement reveals a substantial increase in free cash flow growth rate of 287.09% in the TTM period, which is a positive sign. However, both operating and free cash flows are negative, and the operating cash flow to net income ratio is also negative, indicating cash flow challenges despite the growth in free cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.08M6.77M44.38M122.65M79.04M14.51M
Gross Profit2.06M-150.00K16.24M70.65M32.81M4.61M
EBITDA-24.81M-32.34M-14.83M28.73M11.39M-1.49M
Net Income-41.70M-53.36M-16.78M18.46M6.27M-2.13M
Balance Sheet
Total Assets65.70M63.20M91.93M87.65M89.30M31.41M
Cash, Cash Equivalents and Short-Term Investments405.00K678.00K4.74M17.44M17.51M8.46M
Total Debt7.68M24.57M18.46M6.96M14.90M14.72M
Total Liabilities58.84M55.85M42.54M24.02M30.67M20.85M
Stockholders Equity6.86M7.35M49.38M63.63M58.63M10.56M
Cash Flow
Free Cash Flow-22.75M-18.44M-14.50M24.63M-17.85M-4.28M
Operating Cash Flow-22.99M-17.54M-11.35M28.55M-13.62M-2.59M
Investing Cash Flow-40.00K2.42M-1.37M-2.08M-19.67M-1.02M
Financing Cash Flow9.66M14.19M5.76M-26.02M35.13M9.99M

Prophase Labs Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.18
Price Trends
50DMA
0.27
Negative
100DMA
0.34
Negative
200DMA
0.35
Negative
Market Momentum
MACD
-0.05
Negative
RSI
24.81
Positive
STOCH
-1.24
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PRPH, the sentiment is Negative. The current price of 0.18 is above the 20-day moving average (MA) of 0.14, below the 50-day MA of 0.27, and below the 200-day MA of 0.35, indicating a bearish trend. The MACD of -0.05 indicates Negative momentum. The RSI at 24.81 is Positive, neither overbought nor oversold. The STOCH value of -1.24 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PRPH.

Prophase Labs Risk Analysis

Prophase Labs disclosed 63 risk factors in its most recent earnings report. Prophase Labs reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Prophase Labs Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$25.98M-0.84-50.23%-15.61%-68.96%
47
Neutral
$19.68M65.130.27%75.19%
46
Neutral
$5.46M-0.23-37.38%-22.60%53.82%
45
Neutral
$8.19M-1.99-93.87%-0.74%81.49%
40
Underperform
$13.47M-0.38-44.42%-1.50%80.17%
39
Underperform
$517.48K-0.06
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PRPH
Prophase Labs
0.09
-0.54
-85.71%
TXMD
TherapeuticsMD
1.70
0.60
54.55%
AYTU
Aytu BioScience
2.55
1.10
75.86%
YCBD
cbdMD
1.51
-1.23
-44.89%
IMCC
IM Cannabis Corp
1.56
-0.64
-29.09%
FLGC
Flora Growth
7.31
-34.03
-82.32%

Prophase Labs Corporate Events

M&A TransactionsBusiness Operations and Strategy
ProPhase Labs Announces Proposed Reverse Merger with ABL
Positive
Dec 19, 2025

ProPhase Labs, Inc. announced that it has entered into a non-binding letter of intent for a proposed reverse merger with Advanced Biological Laboratories S.A., a European biotechnology company, under which ABL would become the majority owner of the combined entity. The contemplated transaction, if completed, would significantly reshape ProPhase’s ownership structure and strategic direction by aligning it more closely with ABL’s biotech focus, with potential implications for shareholders and the company’s positioning in the broader healthcare and diagnostics market.

Delistings and Listing ChangesStock Split
Prophase Labs Implements Reverse Stock Split
Neutral
Dec 12, 2025

On November 30, 2025, Prophase Labs‘ stockholders approved a reverse stock split of its common stock at a ratio of one share for every ten shares, effective December 2, 2025. This move was aimed at increasing the per-share trading price to meet NASDAQ’s continued listing requirements. The reverse stock split did not alter stockholders’ percentage ownership, except for cash adjustments for fractional shares, and the company’s common stock continues to trade under the symbol ‘PRPH’.

Shareholder MeetingsStock SplitBusiness Operations and Strategy
Prophase Labs Approves Strategic Proposals at Special Meeting
Positive
Nov 26, 2025

On November 24, 2025, ProPhase Labs, Inc. conducted a Special Meeting of Stockholders where six proposals were presented and approved. The proposals included acquiring digital assets, creating a new class of digital treasury shares, issuing digital tokens, and authorizing stock splits. Proposal 4, concerning stock splits, notably met the approval requirements for charter amendments under Delaware law, indicating strong shareholder support and potential strategic shifts for the company.

Private Placements and FinancingBusiness Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
Prophase Labs Secures Forbearance Agreement with Avtech Capital
Neutral
Nov 25, 2025

On November 21, 2025, ProPhase Labs, Inc. received confirmation from Avtech Capital, LLC to continue its forbearance under an existing equipment lease, with a new payment schedule starting November 28, 2025. This arrangement ensures the company can bring its lease current without affecting its operations, liquidity, or financial reporting, as confirmed by their recent Form 10-Q.

Legal Proceedings
Prophase Labs Faces Unsealed Civil Action Disclosure
Neutral
Nov 25, 2025

On November 21, 2025, ProPhase Labs, Inc. disclosed that a civil action filed against it in 2023 had been unsealed by court order on November 4, 2025. The unsealing is a procedural step under the False Claims Act, and the company was unaware of the action until November 19, 2025. ProPhase Labs has not been served with the complaint and has received no indication of governmental intervention. The company denies any wrongdoing, maintains its compliance standards, and intends to defend itself vigorously. It also notes that a separate private dispute with Dr. Hennrick was resolved in April 2024. The company does not expect the unsealed matter to impact its operations.

Product-Related AnnouncementsM&A TransactionsLegal ProceedingsBusiness Operations and Strategy
Prophase Labs Unveils Strategic Initiatives and Partnerships
Positive
Nov 19, 2025

On November 19, 2025, ProPhase Labs announced its strategic initiatives, including M&A discussions and the commercialization of the BE-Smart™ Esophageal Cancer Test following a landmark study. The company is also pursuing a $50 million collection initiative through Crown Medical, which has been appointed as Special Counsel to expedite litigation against insurance carriers. These efforts aim to unlock significant value for ProPhase, which it believes is not reflected in its current share price.

Private Placements and FinancingBusiness Operations and Strategy
ProPhase Labs Signs Sales Agreement with WestPark Capital
Neutral
Oct 15, 2025

On October 9, 2025, ProPhase Labs, Inc. entered into an At-the-Market Sales Agreement with WestPark Capital, Inc., allowing the company to offer and sell shares of its common stock through the agent. This agreement, underpinned by the company’s effective registration statement and related prospectus, provides ProPhase Labs with flexibility in its stock offerings, potentially impacting its market presence and financial strategy. The agreement includes customary provisions and allows for termination by either party, reflecting a strategic move to manage its capital and shareholder interests.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 20, 2025