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Prophase Labs (PRPH)
NASDAQ:PRPH
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Prophase Labs (PRPH) AI Stock Analysis

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PRPH

Prophase Labs

(NASDAQ:PRPH)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
$0.50
▲(78.57% Upside)
Prophase Labs' overall stock score is primarily impacted by its financial performance challenges, including declining revenues and negative profitability. Technical analysis indicates bearish momentum, and valuation metrics reflect financial distress. While the earnings call provided some optimism with potential cash recovery and new ventures, these are offset by current financial and market concerns.

Prophase Labs (PRPH) vs. SPDR S&P 500 ETF (SPY)

Prophase Labs Business Overview & Revenue Model

Company DescriptionProPhase Labs, Inc. engages in the research, development, manufacture, distribution, marketing, and sale of over the counter (OTC) consumer healthcare products and dietary supplements in the United States. The company operates in two segments, Diagnostic Services and Consumer Products. It offers a range of OTC dietary supplements, including Legendz XL for male sexual health; and Triple Edge XL, an energy and stamina booster. The company also provides contract manufacturing services, such as product development, pre-commercialization, production, warehousing, and distribution; SARS-CoV-2 (COVID-19) and COVID-19 viral mutation polymerase chain reaction tests through saliva and nasal swab methods; and other respiratory pathogen panel molecular testing services, as well as personal genomics products and services. It serves national chain drug, internet-based, and various regional retailers. The company was formerly known as The Quigley Corporation. ProPhase Labs, Inc. was founded in 1989 and is headquartered in Garden City, New York.
How the Company Makes MoneyProphase Labs generates revenue through several key streams, including the sale of its proprietary diagnostic products, therapeutic solutions, and any associated licensing agreements. The company may also form strategic partnerships with other biotech firms, healthcare providers, or research institutions to co-develop products or services, which can lead to additional revenue through collaboration fees or shared profits. Additionally, Prophase Labs may receive funding from government grants or private investments aimed at supporting research and development initiatives, further contributing to its overall earnings.

Prophase Labs Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Apr 01, 2026
Earnings Call Sentiment Neutral
The earnings call provided a mix of optimistic future prospects and current financial challenges. While there are significant potential opportunities, such as large cash recovery and new ventures, there are also current concerns regarding stock performance and financial stability.
Q2-2025 Updates
Positive Updates
Potential $50 Million Recovery from COVID-19 Receivables
ProPhase Labs is targeting over $50 million in net near-term cash recovery from COVID-19 receivables through a legal strategy involving Crown Medical collections and 1,100 insurance companies.
Advancement in Esophageal Cancer Test
ProPhase Labs has been awarded a critical patent for its BE-Smart esophageal cancer test, which has the potential to diagnose esophageal cancer earlier and more accurately, potentially saving lives and reducing healthcare costs.
Restructuring of Nebula Genomics
Nebula Genomics has been restructured to reduce costs significantly, and the company is exploring strategic alternatives which may include a potential sale.
Crypto Treasury Strategy Initiative
ProPhase Labs is exploring entering the crypto treasury strategy with potential significant partners, which could provide substantial financial growth opportunities.
Negative Updates
Stock Price and Market Cap Concerns
The stock price has seen a significant drop to $0.35, with a market cap of around $13 million to $15 million, reflecting possible market concerns.
Dilution and Financial Distress
ProPhase Labs has experienced stock price crashes and dilution, along with financial distress from interest expenses and debt.
Uncertainty in Equivir Studies
The final clinical studies for Equivir have not met initial expectations, and results are still pending, causing delays in further development.
Company Guidance
During the ProPhase Labs Second Quarter 2025 Results call, CEO Ted Karkus provided guidance on several key initiatives and metrics. He highlighted the company's ongoing efforts to recover $50 million from COVID-19 receivables through Crown Medical collections, an amount that is more than triple the company's current market cap of around $0.35 per share. Karkus expressed confidence in the anticipated recovery, noting that Crown Medical's analysis suggests a net amount of approximately $73 million, with ProPhase retaining about $50 million after contingency fees. Additionally, Karkus discussed the BE-Smart esophageal cancer test, emphasizing its potential to significantly impact the market by offering a more accurate diagnostic test for esophageal cancer, a disease with a high mortality rate. He also mentioned the restructuring of Nebula Genomics, which now operates with reduced overhead, and the potential for future growth or sale. Karkus concluded by discussing the upcoming proxy vote to increase authorized shares to 1 billion, aiming to attract large partners for a potential crypto treasury strategy, drawing parallels to the company's previous success in pivoting to COVID testing.

Prophase Labs Financial Statement Overview

Summary
Prophase Labs faces significant financial challenges, with declining revenues and negative profitability metrics. The balance sheet shows moderate leverage but poor returns on equity. Cash flow issues persist, with negative operating and free cash flows. The company needs to address revenue volatility and improve operational efficiency to enhance financial stability.
Income Statement
45
Neutral
Prophase Labs has experienced significant revenue decline, with a TTM revenue growth rate of -26.87%. The company also shows negative profitability margins, including a net profit margin of -12.41% and an EBIT margin of -9.58%, indicating challenges in maintaining profitability. Historical data shows a peak in revenue in 2022, followed by a steep decline, highlighting volatility in revenue streams.
Balance Sheet
50
Neutral
The balance sheet reflects moderate leverage with a TTM debt-to-equity ratio of 0.48, which is an improvement from the previous year's 3.34. However, the return on equity is significantly negative at -230.18%, indicating poor returns for shareholders. The equity ratio stands at 27.21%, suggesting a moderate reliance on equity financing.
Cash Flow
40
Negative
Cash flow analysis reveals negative operating cash flow and free cash flow, with a TTM free cash flow growth rate of -39.87%. The operating cash flow to net income ratio is negative, reflecting cash flow challenges. Despite this, the free cash flow to net income ratio is close to 1, indicating that free cash flow is nearly equivalent to net income, albeit both are negative.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue3.34M6.77M44.38M122.65M79.04M14.51M
Gross Profit2.02M-150.00K16.24M70.65M32.81M4.61M
EBITDA-26.18M-32.34M-14.83M28.73M11.39M-1.49M
Net Income-41.45M-53.36M-16.78M18.46M6.27M-2.13M
Balance Sheet
Total Assets42.04M63.20M91.93M87.65M89.30M31.41M
Cash, Cash Equivalents and Short-Term Investments171.00K678.00K4.74M17.44M17.26M8.46M
Total Debt5.54M24.57M21.38M6.96M14.90M14.72M
Total Liabilities30.61M55.85M42.54M24.02M30.67M20.85M
Stockholders Equity11.44M7.35M49.38M63.63M58.63M10.56M
Cash Flow
Free Cash Flow-6.03M-18.44M-14.50M24.63M-17.85M-4.28M
Operating Cash Flow-6.09M-17.54M-11.35M28.55M-13.62M-2.59M
Investing Cash Flow783.00K2.42M-1.37M-2.08M-19.67M-1.02M
Financing Cash Flow8.79M14.19M5.76M-26.02M35.13M9.99M

Prophase Labs Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.28
Price Trends
50DMA
0.43
Negative
100DMA
0.40
Negative
200DMA
0.38
Negative
Market Momentum
MACD
-0.05
Positive
RSI
30.93
Neutral
STOCH
8.88
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PRPH, the sentiment is Negative. The current price of 0.28 is below the 20-day moving average (MA) of 0.40, below the 50-day MA of 0.43, and below the 200-day MA of 0.38, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 30.93 is Neutral, neither overbought nor oversold. The STOCH value of 8.88 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PRPH.

Prophase Labs Risk Analysis

Prophase Labs disclosed 63 risk factors in its most recent earnings report. Prophase Labs reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Prophase Labs Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$21.11M-0.76-60.76%-18.05%33.87%
47
Neutral
$13.54M-29.32-1.98%156.93%92.75%
45
Neutral
$12.12M-0.19
40
Underperform
$7.21M-0.13-33.13%-7.80%90.17%
38
Underperform
$6.72M-2.36-36.94%2.17%88.34%
38
Underperform
$6.77M-0.23-37.38%-22.60%53.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PRPH
Prophase Labs
0.28
-0.50
-63.85%
TXMD
TherapeuticsMD
1.39
-0.13
-8.55%
AYTU
Aytu BioScience
2.03
0.39
23.78%
YCBD
cbdMD
0.80
-2.72
-77.27%
IMCC
IM Cannabis Corp
1.29
-0.83
-39.15%
FLGC
Flora Growth
8.01
-41.52
-83.83%

Prophase Labs Corporate Events

Business Operations and StrategyPrivate Placements and Financing
ProPhase Labs Signs Sales Agreement with WestPark Capital
Neutral
Oct 15, 2025

On October 9, 2025, ProPhase Labs, Inc. entered into an At-the-Market Sales Agreement with WestPark Capital, Inc., allowing the company to offer and sell shares of its common stock through the agent. This agreement, underpinned by the company’s effective registration statement and related prospectus, provides ProPhase Labs with flexibility in its stock offerings, potentially impacting its market presence and financial strategy. The agreement includes customary provisions and allows for termination by either party, reflecting a strategic move to manage its capital and shareholder interests.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
ProPhase Labs Partners with ThinkEquity for $6M Placement
Neutral
Sep 18, 2025

On September 12, 2025, ProPhase Labs entered into a Strategic Advisory and Private Placement Agreement with ThinkEquity LLC to serve as its exclusive strategic advisor, placement agent, and investment banker. The agreement involves a proposed private placement of approximately $6 million in securities, with ThinkEquity receiving compensation in cash and warrants. This strategic move is part of ProPhase Labs’ digital asset treasury strategy, potentially impacting its operations and market positioning by involving significant crypto asset accumulation and board representation rights for ThinkEquity.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyStock BuybackShareholder Meetings
Prophase Labs Approves Strategic Amendments at Special Meeting
Positive
Sep 15, 2025

On September 9, 2025, ProPhase Labs held a Special Meeting of Stockholders where 63.54% of shares were voted. The stockholders approved several proposals including amendments to equity compensation plans, an increase in authorized shares, a share repurchase program, and changes to the company’s bylaws, indicating strategic adjustments to enhance operational flexibility and shareholder value.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

ProPhase Labs Earnings Call: Balancing Optimism and Challenges
Sep 1, 2025

ProPhase Labs’ recent earnings call painted a picture of both optimism and caution, reflecting a balance between promising future prospects and current financial hurdles. The company is poised for potential growth through strategic initiatives, yet faces challenges with stock performance and financial stability.

Private Placements and Financing
Prophase Labs Ends Stock Purchase Agreement with Keystone
Neutral
Aug 28, 2025

On August 27, 2025, ProPhase Labs, Inc. announced the termination of its Common Stock Purchase Agreement with Keystone Capital Partners, LLC, which was initially established on January 29, 2025. This agreement allowed ProPhase Labs to sell shares of its common stock to Keystone up to approximately $7.7 million. The termination, effective August 28, 2025, was executed at the company’s discretion without any penalties or fees, and there are no other material relationships between the two entities.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

Business Operations and StrategyStock BuybackRegulatory Filings and ComplianceShareholder Meetings
Prophase Labs Files Proxy, Reschedules Shareholder Meeting
Positive
Aug 19, 2025

On August 19, 2025, ProPhase Labs announced the filing of a definitive proxy statement with the SEC and received a ‘no further comments’ letter, indicating the completion of the SEC’s review. The Special Meeting of Shareholders was rescheduled to September 9, 2025, to ensure proper dissemination of proxy materials. The Board recommends shareholders vote ‘FOR’ proposals aimed at strategic growth, including increasing authorized shares and a $15 million share repurchase program. These initiatives are intended to support the company’s crypto treasury strategy, attract major industry partners, and enhance financial flexibility, potentially increasing long-term shareholder value.

The most recent analyst rating on (PRPH) stock is a Hold with a $0.50 price target. To see the full list of analyst forecasts on Prophase Labs stock, see the PRPH Stock Forecast page.

ProPhase Labs Reports Turnaround and Strategic Growth
Aug 14, 2025

ProPhase Labs Inc. is a diversified company operating in the biotech, genomics, and consumer healthcare sectors, known for its innovative diagnostics and consumer health products. In its latest earnings report, ProPhase Labs announced significant operational and financial improvements for the three and six months ending June 30, 2025, highlighting a strategic shift towards non-dilutive liquidity initiatives and transformational growth catalysts.

Business Operations and StrategyFinancial DisclosuresProduct-Related Announcements
ProPhase Labs Achieves Key U.S. Patent for Test
Positive
Aug 13, 2025

ProPhase Labs reported significant financial and operational improvements for the first half of 2025, including a strengthened equity position and reduced liabilities. The company achieved a key U.S. patent for its BE-Smart™ Esophageal Adenocarcinoma Risk Assessment test, positioning it for faster market entry. Additionally, ProPhase streamlined its operations, reduced costs, and improved margins, setting a path for future growth. The company is also exploring a strategic treasury initiative involving digital assets to complement its core businesses.

Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and Compliance
ProPhase Labs Appoints New Fractional CFO
Neutral
Aug 6, 2025

ProPhase Labs, Inc. announced the resignation of its Chief Operating Officer, Stu Hollenshead, effective July 31, 2025, who will transition to a marketing consultant role. The company is searching for a successor, with interim duties managed by the executive team. Additionally, ProPhase Labs appointed Steven M. Plumb as its fractional Chief Financial Officer on August 6, 2025. Plumb, a seasoned financial executive, will provide operational advice and oversee SEC filings, while CEO Ted Karkus remains the principal financial officer.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 04, 2025