Pmv Pharmaceuticals, Inc. (PMVP)
NASDAQ:PMVP
Rosuvastatin 10 Mg Tablet, Rezatapopt, Metformin Hydrochloride 500 Mg Tablet, Repaglinide 0.5 Mg Tablet, Midazolam Hydrochloride Syrup
Advanced Solid Tumors, Tp53 Y220c Mutation
Phase I
Recruiting
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Jan 05, 2026
―
Itraconazole, Pc14586
Healthy Volunteers
Phase I
Completed
A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants
Mar 25, 2024
―
Rabeprazole, Famotidine, Pc14586
Healthy Volunteers
Phase I
Completed
A Study to Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants
Sep 08, 2023
―
Pc14586
Healthy Volunteers
Phase I
Completed
Effect of Food on PC14586 in Healthy Volunteers and the PK of PC14586 in Healthy Japanese Volunteers
Jan 07, 2022
―
Pembrolizumab, Rezatapopt
Colorectal Cancer, Endometrial Cancer, Non-small Cell Lung Cancer, Non-small Cell Lung Carcinoma, Lung Cancer, Ovarian Cancer, Breast Cancer, Prostate Cancer, Metastatic Solid Tumor, Advanced Solid Tumor, Triple Negative Breast Cancer, Small Cell Lung Cancer, Nsclc, Head And Neck Cancer, Metastatic Cancer, Small Cell Lung Carcinoma, Er/Pr Positive Breast Cancer, Nsclc (Non-Small Cell Lung Cancer), Sclc, Her2-Negative Breast Cancer, Her2-Positive Breast Cancer, Gall Bladder Cancer, Small Cell Lung Cancer ( Sclc ), Er/Pr(+), Her2(-) Breast Cancer, Advanced Malignant Neoplasm, Other Cancer, Locally Advanced, Tnbc, Her2+ Breast Cancer, Her2- Breast Cancer
Phase I/II
Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Oct 01, 2020
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Pmv Pharmaceuticals, Inc. (PMVP) have in its pipeline
PMVP is currently developing the following drugs: Rosuvastatin 10 Mg Tablet, Rezatapopt, Metformin Hydrochloride 500 Mg Tablet, Repaglinide 0.5 Mg Tablet, Midazolam Hydrochloride Syrup, Itraconazole, Pc14586, Rabeprazole, Famotidine, Pc14586. These drug candidates are in various stages of clinical development as the company works toward FDA approval.