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Palisade Bio (PALI)
NASDAQ:PALI
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Palisade Bio (PALI) AI Stock Analysis

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PALI

Palisade Bio

(NASDAQ:PALI)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$2.00
▼(-1.48% Downside)
Action:Reiterated
Date:08/11/26
The score is held back primarily by weak financial performance: pre-revenue results, widening losses, and sustained negative free cash flow with rising burn. Technicals are a modest positive as the stock trades above key moving averages with moderately positive momentum. Valuation remains constrained by losses (negative P/E), and the recent increase in authorized shares adds potential dilution risk despite improving financing flexibility.
Positive Factors
Balance-sheet strength
Low leverage and a sizable equity base give Palisade structural financial flexibility uncommon for pre-revenue biotechs. This supports continued R&D spending and reduces near-term refinancing risk, lengthening the runway for clinical programs and strategic optionality over months.
Negative Factors
Pre-revenue with widening losses
The company remains essentially pre-revenue while operating losses roughly doubled year-over-year. Persistent negative profitability and rising spending compress returns and increase reliance on external capital, pressuring the business if clinical progress or funding access slows.
Read all positive and negative factors
Positive Factors
Negative Factors
Balance-sheet strength
Low leverage and a sizable equity base give Palisade structural financial flexibility uncommon for pre-revenue biotechs. This supports continued R&D spending and reduces near-term refinancing risk, lengthening the runway for clinical programs and strategic optionality over months.
Read all positive factors

Palisade Bio (PALI) vs. SPDR S&P 500 ETF (SPY)

Palisade Bio Business Overview & Revenue Model

Company Description
Palisade Bio, Inc. is a clinical-stage biopharmaceutical firm dedicated to identifying, advancing, and bringing to market orally administered treatments for significant conditions stemming from a compromised gastrointestinal mucosal barrier. The c...
How the Company Makes Money
null...

Palisade Bio Financial Statement Overview

Summary
Income statement and cash flow are the main drags: the company is essentially pre-revenue and losses widened materially in TTM, while free cash flow remains meaningfully negative with increased cash burn. The balance sheet is a partial offset with negligible debt and a sizable equity base, but returns remain deeply negative due to ongoing losses.
Income Statement
12
Very Negative
Balance Sheet
68
Positive
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue500.00K0.000.00250.00K0.000.00
Gross Profit500.00K0.000.00250.00K0.000.00
EBITDA-33.22M-16.77M-14.42M-12.28M-14.24M-24.22M
Net Income-31.94M-16.78M-14.44M-12.30M-14.26M-26.62M
Balance Sheet
Total Assets127.31M134.34M10.88M14.05M15.76M12.51M
Cash, Cash Equivalents and Short-Term Investments125.17M133.38M9.82M12.43M12.38M10.49M
Total Debt0.0071.00K169.00K369.00K404.00K199.00K
Total Liabilities5.57M4.96M3.39M2.74M3.28M5.15M
Stockholders Equity121.75M129.38M7.49M11.31M12.48M7.37M
Cash Flow
Free Cash Flow-18.19M-10.85M-12.19M-11.14M-13.37M-14.77M
Operating Cash Flow-18.19M-10.85M-12.19M-11.13M-13.36M-14.77M
Investing Cash Flow0.000.000.00-4.00K-10.00K-54.00K
Financing Cash Flow137.97M134.44M9.58M11.19M15.26M24.61M

Palisade Bio Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.03
Price Trends
50DMA
1.94
Positive
100DMA
1.98
Positive
200DMA
1.93
Positive
Market Momentum
MACD
0.04
Negative
RSI
57.04
Neutral
STOCH
72.86
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PALI, the sentiment is Positive. The current price of 2.03 is above the 20-day moving average (MA) of 2.01, above the 50-day MA of 1.94, and above the 200-day MA of 1.93, indicating a bullish trend. The MACD of 0.04 indicates Negative momentum. The RSI at 57.04 is Neutral, neither overbought nor oversold. The STOCH value of 72.86 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PALI.

Palisade Bio Risk Analysis

Palisade Bio disclosed 52 risk factors in its most recent earnings report. Palisade Bio reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Palisade Bio Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$201.47M-2.13-135.60%291.42%11.70%
53
Neutral
$188.77M-1.56-87.05%-29.66%
52
Neutral
$341.57M-4.04-33.47%91.31%
52
Neutral
$265.66M-4.49-133.09%986.14%45.31%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$291.00M-0.24-96.80%-1.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PALI
Palisade Bio
2.15
1.33
162.20%
CRBP
Corbus Pharmaceuticals
10.08
0.45
4.67%
ELDN
Eledon Pharmaceuticals
3.70
1.10
42.31%
OBIO
Orchestra BioMed Holdings
4.45
1.79
67.29%
PYXS
Pyxis Oncology
3.01
1.88
166.37%

Palisade Bio Corporate Events

Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and ComplianceShareholder Meetings
Palisade Bio Shareholders Approve Charter Amendments, Governance Matters
Positive
Jun 11, 2026
At its annual meeting on June 10, 2026, Palisade Bio stockholders approved all seven proposals on the ballot, including the election of four directors to serve until the 2027 meeting and ratification of Baker Tilly US, LLP as independent auditor f...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 11, 2026