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Palisade Bio (PALI)
NASDAQ:PALI

Palisade Bio (PALI) AI Stock Analysis

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PALI

Palisade Bio

(NASDAQ:PALI)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$2.00
▼(-2.91% Downside)
Action:ReiteratedDate:04/03/26
The score is primarily constrained by weak financial performance (minimal revenue, ongoing losses, and persistent cash burn), partially offset by a low-debt profile and strengthened capitalization. Technicals are broadly neutral with only modest positive momentum, while valuation signals are unfavorable due to negative earnings; a recent partnership/financing event provides some supportive upside.
Positive Factors
Strengthened capitalization / low leverage
A material recapitalization in 2025 meaningfully improves the balance sheet and reduces financial risk. With near-zero debt and a larger equity base, Palisade can better fund upcoming clinical milestones, extend runway, and negotiate partnerships without immediate liquidity pressure—supporting durable execution capacity over the next several quarters.
Negative Factors
Persistent cash burn
Sustained negative operating and free cash flow necessitates ongoing external financing or partnerships to fund operations. Even with some improvement in 2025, continued cash burn increases dilution and execution risk if market access for capital tightens, making multi-quarter progress dependent on successful funding or milestone-based deals.
Read all positive and negative factors
Positive Factors
Negative Factors
Strengthened capitalization / low leverage
A material recapitalization in 2025 meaningfully improves the balance sheet and reduces financial risk. With near-zero debt and a larger equity base, Palisade can better fund upcoming clinical milestones, extend runway, and negotiate partnerships without immediate liquidity pressure—supporting durable execution capacity over the next several quarters.
Read all positive factors

Palisade Bio (PALI) vs. SPDR S&P 500 ETF (SPY)

Palisade Bio Business Overview & Revenue Model

Company Description
Palisade Bio, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, developing, and commercializing oral therapies that target serious diseases associated with the breakdown of the mucosal barrier protecting the gastrointestina...
How the Company Makes Money
null...

Palisade Bio Financial Statement Overview

Summary
R&D-stage profile with near-zero revenue, persistent operating/net losses, and consistently negative operating/free cash flow. Positives include very low debt and a much stronger 2025 balance sheet (likely extending runway), but profitability and self-funding capability remain weak.
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.00250.00K0.000.00
Gross Profit-3.00K0.00250.00K0.000.00
EBITDA-18.06M-14.42M-12.28M-14.24M-24.22M
Net Income-16.78M-14.44M-12.30M-14.26M-26.62M
Balance Sheet
Total Assets134.34M10.88M14.05M15.76M12.51M
Cash, Cash Equivalents and Short-Term Investments133.38M9.82M12.43M12.38M10.49M
Total Debt71.00K169.00K369.00K404.00K199.00K
Total Liabilities4.96M3.39M2.74M3.28M5.15M
Stockholders Equity129.38M7.49M11.31M12.48M7.37M
Cash Flow
Free Cash Flow-10.85M-12.19M-11.14M-13.37M-14.77M
Operating Cash Flow-10.85M-12.19M-11.13M-13.36M-14.77M
Investing Cash Flow0.000.00-4.00K-10.00K-54.00K
Financing Cash Flow134.44M9.58M11.19M15.26M24.61M

Palisade Bio Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.06
Price Trends
50DMA
1.82
Positive
100DMA
1.89
Positive
200DMA
1.51
Positive
Market Momentum
MACD
0.03
Negative
RSI
57.96
Neutral
STOCH
82.20
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PALI, the sentiment is Positive. The current price of 2.06 is above the 20-day moving average (MA) of 1.93, above the 50-day MA of 1.82, and above the 200-day MA of 1.51, indicating a bullish trend. The MACD of 0.03 indicates Negative momentum. The RSI at 57.96 is Neutral, neither overbought nor oversold. The STOCH value of 82.20 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PALI.

Palisade Bio Risk Analysis

Palisade Bio disclosed 48 risk factors in its most recent earnings report. Palisade Bio reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Palisade Bio Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$180.56M-1.38-65.76%-17.43%
56
Neutral
$244.24M-2.71-46.46%72.35%
52
Neutral
$251.64M-3,008.78-169.64%6.46%-14.32%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$330.11M-7.80-228.64%71.95%
46
Neutral
$107.44M-0.90-87.28%-82.53%-52.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PALI
Palisade Bio
2.06
1.39
207.46%
CRBP
Corbus Pharmaceuticals
10.02
4.03
67.28%
ELDN
Eledon Pharmaceuticals
3.20
0.19
6.31%
OBIO
Orchestra BioMed Holdings
4.51
1.69
59.93%
PYXS
Pyxis Oncology
1.70
0.78
84.78%

Palisade Bio Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Palisade Bio partners with Iterative Health to advance PALI-2108
Positive
Apr 2, 2026
On March 30, 2026, Palisade Bio, Inc. entered into a master services agreement with Iterative Scopes, Inc., doing business as Iterative Health, to support and accelerate patient enrollment for an anticipated Phase 2 study of its ulcerative colitis...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 03, 2026