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OmniAb (OABI)
NASDAQ:OABI
US Market
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OmniAb (OABI) AI Stock Analysis

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OABI

OmniAb

(NASDAQ:OABI)

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Neutral 55 (OpenAI - 5.2)
Rating:55Neutral
Price Target:
$3.00
▲(82.93% Upside)
Action:Reiterated
Date:05/15/26
The score is held back primarily by weak financial quality (large losses and renewed cash burn) and loss-based valuation (negative P/E). Offsetting these are constructive technical momentum (above major moving averages with positive MACD) and a positive earnings-call update featuring raised revenue guidance and strong operational momentum, tempered by milestone revenue lumpiness and expected cash drawdown.
Positive Factors
Contracted Milestones & Royalties
A large, contractually-backed milestone and royalty pool gives multi-year optionality beyond fee-for-service work. Contracted economics provide durable upside as clinical programs advance, creating asymmetric payoffs that can convert intermittent milestones into long-term royalty streams as approvals occur.
Negative Factors
Sustained Cash Burn
Persistent negative operating and free cash flow indicates structural cash consumption rather than one-off timing. Continued burn increases dependency on external financing or milestone timing, which can dilute shareholders or constrain investments if partner milestones do not materialize on schedule.
Read all positive and negative factors
Positive Factors
Negative Factors
Contracted Milestones & Royalties
A large, contractually-backed milestone and royalty pool gives multi-year optionality beyond fee-for-service work. Contracted economics provide durable upside as clinical programs advance, creating asymmetric payoffs that can convert intermittent milestones into long-term royalty streams as approvals occur.
Read all positive factors

OmniAb (OABI) vs. SPDR S&P 500 ETF (SPY)

OmniAb Business Overview & Revenue Model

Company Description
OmniAb, Inc., a biotechnology company, provides therapeutic antibody discovery technologies in the United States. The company's discovery platform provides industry partners access to the diverse antibody repertoires and screening technologies to ...
How the Company Makes Money
OmniAb primarily makes money by licensing access to its antibody discovery platform and associated intellectual property to drug developers, and by receiving downstream economics when partnered programs progress and generate commercial value. Key ...

OmniAb Earnings Call Summary

Earnings Call Date:May 07, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Positive
The call conveyed strong positive operational and commercial momentum: a large YoY revenue surge driven by partner milestones, multiple clinical advancements (including OmnidAb entrants and a Phase III progression), improved operating efficiencies, raised revenue guidance, healthy technology traction (xPloration and OmniUltra) and a solid near-term cash balance. Offsetting items include a $2.9M noncash impairment that increased GAAP expense guidance, continued reliance on lumpy milestone revenue rather than royalties, ongoing net losses, and projected year-end cash decline. Overall, the positive operational and revenue developments and guidance raise materially outweigh the lowlights, though risks from milestone variability and funding remain.
Positive Updates
Strong Quarter Revenue Growth
Total revenue of $14.4M in Q1 2026 versus $4.2M in Q1 2025, an increase of approximately 243%, driven primarily by higher milestone revenue from partner clinical progress.
Negative Updates
Noncash Impairment Charge
Recorded a $2.9M noncash write-off related to legacy small-molecule ion channel intangible assets in Q1 2026; drove higher GAAP operating expense and raised GAAP operating expense guidance to $83M–$88M for 2026.
Read all updates
Q1-2026 Updates
Negative
Strong Quarter Revenue Growth
Total revenue of $14.4M in Q1 2026 versus $4.2M in Q1 2025, an increase of approximately 243%, driven primarily by higher milestone revenue from partner clinical progress.
Read all positive updates
Company Guidance
OmniAb raised its 2026 revenue outlook to $28–33 million after a strong Q1 (Q1 revenue $14.4M vs $4.2M a year ago), ending the quarter with $49.1M in cash; management now expects 2026 GAAP operating expenses of $83–88M (driven in part by a $2.9M noncash impairment recorded in Q1) while keeping cash operating expense guidance unchanged at $50–55M, and projects year‑end cash of $33–38M with an effective tax rate of ~0%. Q1 operating expense was $22.3M (R&D $9.6M, G&A $6.6M), net loss was $7.7M (‑$0.06/share) or ‑$0.04/share excluding the one‑time charge, and management highlighted portfolio metrics that underpin the outlook: 107 active partners, 409 active programs, 32 active clinical/approved programs, >$3B of total contracted milestones with an average royalty of ~3.4%, and roughly $350M of remaining potential milestones from clinical‑stage programs.

OmniAb Financial Statement Overview

Summary
Revenue rebounded strongly in the TTM period, and leverage is low (supportive balance sheet). However, profitability remains deeply negative and cash flow is a key risk with meaningful operating/free-cash-flow burn and worsening TTM free cash flow.
Income Statement
32
Negative
Balance Sheet
68
Positive
Cash Flow
36
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue28.91M18.67M26.39M34.16M59.08M34.75M
Gross Profit10.25M-3.39M26.39M34.16M59.08M34.75M
EBITDA-35.11M-49.76M-50.92M-49.92M-8.40M-18.09M
Net Income-54.28M-64.78M-62.03M-50.62M-22.33M-27.04M
Balance Sheet
Total Assets293.65M300.91M325.56M375.23M421.21M304.46M
Cash, Cash Equivalents and Short-Term Investments49.07M54.02M59.43M86.98M88.27M0.00
Total Debt19.67M20.33M23.16M25.56M25.80M13.85M
Total Liabilities31.00M33.89M37.94M60.64M79.84M70.16M
Stockholders Equity262.65M267.03M287.62M314.58M341.37M234.31M
Cash Flow
Free Cash Flow-26.02M-37.02M-41.54M703.00K-20.75M-9.74M
Operating Cash Flow-25.50M-36.45M-39.66M2.35M-3.59M-5.67M
Investing Cash Flow15.78M6.47M37.88M-18.38M-73.31M-4.03M
Financing Cash Flow27.87M27.91M13.02M-892.00K110.74M9.70M

OmniAb Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.64
Price Trends
50DMA
1.76
Positive
100DMA
1.79
Positive
200DMA
1.76
Positive
Market Momentum
MACD
0.30
Negative
RSI
79.90
Negative
STOCH
90.07
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OABI, the sentiment is Positive. The current price of 1.64 is below the 20-day moving average (MA) of 2.08, below the 50-day MA of 1.76, and below the 200-day MA of 1.76, indicating a bullish trend. The MACD of 0.30 indicates Negative momentum. The RSI at 79.90 is Negative, neither overbought nor oversold. The STOCH value of 90.07 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for OABI.

OmniAb Risk Analysis

OmniAb disclosed 75 risk factors in its most recent earnings report. OmniAb reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

OmniAb Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$444.81M-5.46-37.57%24.50%
55
Neutral
$394.33M-6.38-20.31%8.21%21.41%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$813.33M>-0.0187.31%-1004.74%
49
Neutral
$378.53M-2.18-57.01%-28.75%
48
Neutral
$211.84M-1.33194.13%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OABI
OmniAb
2.70
1.29
91.49%
RNAC
Cartesian Therapeutics
7.54
-2.44
-24.45%
TLSA
Tiziana Life Sciences
1.41
-0.03
-2.08%
AVIR
Atea Pharmaceuticals
4.67
1.57
50.65%
VOR
Vor Biopharma
14.97
10.28
219.19%
SGMT
Sagimet Biosciences, Inc. Class A
7.29
3.80
108.88%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 15, 2026