OmniAb (OABI)
NASDAQ:OABI
US Market
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OmniAb (OABI) AI Stock Analysis

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OABI

OmniAb

(NASDAQ:OABI)

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Neutral 51 (OpenAI - 4o)
Rating:51Neutral
Price Target:
$1.50
▼(-3.85% Downside)
OmniAb's overall stock score reflects a challenging financial environment with significant net losses and negative revenue growth. While the company demonstrates strong gross margins and low leverage, these are overshadowed by profitability challenges. Technical analysis indicates a neutral to slightly bearish trend, and valuation metrics are concerning due to ongoing losses. However, the company's strategic initiatives and expanded partnerships provide some optimism for future growth.
Positive Factors
Partnership Expansion
The increase in active partnerships enhances OmniAb's market reach and potential revenue streams, supporting long-term growth and stability.
Innovative Product Launch
OmniUltra's launch opens new market opportunities, potentially driving future revenue and establishing OmniAb as a leader in innovative antibody solutions.
Financial Flexibility
The private placement strengthens OmniAb's balance sheet, providing the financial resources needed to invest in growth initiatives and weather economic challenges.
Negative Factors
Revenue Decline
The significant drop in revenue indicates challenges in achieving sales targets, which could hinder the company's ability to fund operations and growth.
Delayed Milestones
Delays in achieving milestones can impact revenue projections and investor confidence, potentially affecting long-term strategic goals.
Negative Profit Margins
Substantial losses and negative profit margins highlight operational inefficiencies, posing a risk to financial sustainability and shareholder value.

OmniAb (OABI) vs. SPDR S&P 500 ETF (SPY)

OmniAb Business Overview & Revenue Model

Company DescriptionOmniAb, Inc., a biotechnology company, provides therapeutic antibody discovery technologies in the United States. The company's discovery platform provides industry partners access to the diverse antibody repertoires and screening technologies to enable discovery of next-generation therapeutics. Its OmniAb platform is the biological intelligence of proprietary transgenic animals, including OmniRat, OmniChicken, and OmniMouse that have been genetically modified to generate antibodies with human sequences to facilitate development of human therapeutic candidates. The company's OmniFlic (transgenic rat) and OmniClic (transgenic chicken) address industry needs for bispecific antibody applications though a common light chain approach, and OmniTaur that features unique structural attributes of cow antibodies for complex targets. The company was founded in 2012 and is headquartered in Emeryville, California.
How the Company Makes MoneyOmniAb generates revenue primarily through its platform technology licensing agreements and collaborative research partnerships with pharmaceutical and biotech companies. The company earns money by charging fees for access to its proprietary antibody discovery platform, which allows clients to develop their own therapeutic candidates more efficiently. Additionally, OmniAb may receive milestone payments and royalties based on the sales of products developed using its technology. Strategic partnerships with larger pharmaceutical firms also contribute to its earnings, as these collaborations often involve upfront payments and shared development costs, enhancing the company's financial stability.

OmniAb Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 25, 2026
Earnings Call Sentiment Neutral
OmniAb's earnings call highlighted substantial progress in expanding partnerships and launching innovative technologies, notably OmniUltra and the xPloration program. However, financial challenges were evident with a decline in Q3 revenue and delayed milestones. Despite these setbacks, the company's strengthened financial position and strategic initiatives are promising.
Q3-2025 Updates
Positive Updates
Record Growth in Program Additions
The number of new program additions in Q3 2025 equaled the total number for all of 2024, indicating a significant uptick in new initiatives and partnerships.
Expansion of Active Partners
OmniAb reached a record high of over 100 active partners, showcasing the company's growing influence and successful partner engagement.
Successful Launch and Demand for xPloration
The xPloration partner access program is gaining strong traction, generating interest and new opportunities, and is expected to be accretive to earnings and cash flow.
OmnidAb-derived Program Enters Clinical Trials
The first OmnidAb-derived program entered human clinical trials, marking a significant milestone for the technology within a short timeframe since its launch.
Introduction of OmniUltra
OmniAb announced the launch of OmniUltra, the first transgenic chicken producing cow-like antibodies with ultra-long CDRH3s, opening new market opportunities.
Strengthened Financial Position
Closed a $30 million private placement in late August, enhancing financial flexibility and strengthening the balance sheet.
Negative Updates
Decrease in Revenue
Revenue for Q3 2025 was $2.2 million, down from $4.2 million in the same period in 2024, due to reduced milestones and lower service revenue.
Milestones Delayed to 2026
Several expected milestones for the second half of 2025 have been pushed to 2026, impacting revenue expectations.
Operating Expenses and Headcount Reduction
Operating expenses were $20.4 million, including a nonrecurring charge of $800,000 related to a headcount reduction.
Company Guidance
During OmniAb's third quarter 2025 financial results call, the company provided detailed guidance on several key metrics. They ended Q3 with 104 active partners, surpassing last year's program adds, and reported a total of 399 active programs, including a net addition of 36 programs year-to-date. Financially, OmniAb reported Q3 revenue of $2.2 million, down from $4.2 million the previous year, primarily due to a reduction in milestones and service revenue. Operating expenses decreased to $20.4 million from $23.9 million in Q3 2024. The company's cash balance as of September 30, 2025, was $59.5 million, bolstered by a $30 million private placement. OmniAb updated its 2025 revenue guidance to $18-$22 million and operating expenses to $82-$86 million. The company expects its cash balance to be between $52 million and $56 million by year-end.

OmniAb Financial Statement Overview

Summary
OmniAb's financial performance is mixed. The company shows strong gross margins and low leverage, indicating operational efficiency and financial stability. However, significant net losses, negative revenue growth, and declining free cash flow growth present substantial challenges. The company needs to focus on improving profitability and cash flow generation to enhance its financial health.
Income Statement
45
Neutral
OmniAb's income statement reveals a challenging financial environment. The company has experienced a decline in revenue, with a negative revenue growth rate of -8.39% TTM. The gross profit margin remains strong at 76.58% TTM, indicating efficient cost management. However, the net profit margin is significantly negative at -301.83% TTM, reflecting substantial losses. EBIT and EBITDA margins are also deeply negative, suggesting operational inefficiencies. Overall, the company faces profitability challenges despite maintaining a solid gross margin.
Balance Sheet
55
Neutral
The balance sheet of OmniAb shows a relatively low debt-to-equity ratio of 0.076 TTM, indicating conservative leverage. However, the return on equity is negative at -22.79% TTM, highlighting the company's struggle to generate returns for shareholders. The equity ratio stands at 89.58% TTM, suggesting a strong equity base relative to total assets. While the company maintains financial stability with low leverage, its inability to generate positive returns is a concern.
Cash Flow
50
Neutral
OmniAb's cash flow statement indicates mixed performance. The operating cash flow to net income ratio is positive at 1.93 TTM, suggesting that operating activities are generating cash despite net losses. However, the free cash flow growth rate is negative at -11.37% TTM, reflecting challenges in sustaining cash flow growth. The free cash flow to net income ratio is close to 1, indicating that free cash flow is nearly matching net income losses. While cash flow from operations is a positive aspect, the decline in free cash flow growth is a concern.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue21.09M26.39M34.16M59.08M34.75M23.27M
Gross Profit16.15M26.39M34.16M59.08M34.75M23.27M
EBITDA-47.65M-50.92M-49.92M-8.40M-18.09M-10.93M
Net Income-63.67M-62.03M-50.62M-22.33M-27.04M-17.56M
Balance Sheet
Total Assets309.69M325.56M375.23M421.21M304.46M295.38M
Cash, Cash Equivalents and Short-Term Investments59.50M59.43M86.98M88.27M0.000.00
Total Debt21.07M23.16M25.56M25.80M13.85M2.59M
Total Liabilities32.25M37.94M60.64M79.84M70.16M59.84M
Stockholders Equity277.44M287.62M314.58M341.37M234.31M235.54M
Cash Flow
Free Cash Flow-35.26M-41.54M703.00K-20.75M-9.74M1.87M
Operating Cash Flow-34.65M-39.66M2.35M-3.59M-5.67M3.62M
Investing Cash Flow4.14M37.88M-18.38M-73.31M-4.03M-26.98M
Financing Cash Flow31.81M13.02M-892.00K110.74M9.70M23.36M

OmniAb Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price1.56
Price Trends
50DMA
1.60
Negative
100DMA
1.75
Negative
200DMA
2.03
Negative
Market Momentum
MACD
-0.03
Negative
RSI
50.28
Neutral
STOCH
73.53
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OABI, the sentiment is Neutral. The current price of 1.56 is above the 20-day moving average (MA) of 1.54, below the 50-day MA of 1.60, and below the 200-day MA of 2.03, indicating a neutral trend. The MACD of -0.03 indicates Negative momentum. The RSI at 50.28 is Neutral, neither overbought nor oversold. The STOCH value of 73.53 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for OABI.

OmniAb Risk Analysis

OmniAb disclosed 77 risk factors in its most recent earnings report. OmniAb reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

OmniAb Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$213.05M-2.44-22.37%3.36%5.15%
47
Neutral
$259.50M-37.98%14.33%
44
Neutral
$240.26M-39.78%-100.00%-62.44%
41
Neutral
$200.48M-0.15
33
Underperform
$68.82M-686.12%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OABI
OmniAb
1.56
-2.16
-58.06%
RNAC
Cartesian Therapeutics
7.46
-11.11
-59.83%
TLSA
Tiziana Life Sciences
1.72
0.69
66.99%
AVIR
Atea Pharmaceuticals
2.96
-0.21
-6.62%
VOR
Vor Biopharma
10.01
-5.62
-35.96%
SGMT
Sagimet Biosciences, Inc. Class A
7.75
3.39
77.75%

OmniAb Corporate Events

OmniAb’s Earnings Call: Progress Amid Challenges
Nov 6, 2025

OmniAb’s recent earnings call painted a picture of both progress and challenges. The company showcased significant advancements in expanding partnerships and launching innovative technologies, such as OmniUltra and the xPloration program. However, financial hurdles were apparent with a notable decline in Q3 revenue and delayed milestones. Despite these setbacks, OmniAb’s strengthened financial position and strategic initiatives offer a promising outlook.

OmniAb Reports Q3 2025 Financial Results and Innovations
Nov 5, 2025

OmniAb, Inc. is a biotechnology company that licenses advanced discovery research technology to pharmaceutical and biotech companies, focusing on creating and screening diverse antibody repertoires for drug development.

Private Placements and FinancingRegulatory Filings and Compliance
OmniAb Announces $30M Private Placement Agreement
Neutral
Aug 25, 2025

On August 24, 2025, OmniAb, Inc. entered into a securities purchase agreement for a private placement of 21,254,106 shares of common stock, expecting to raise approximately $30 million. The proceeds are intended for working capital and general corporate purposes. The private placement is set to close on August 26, 2025, and is conducted in accordance with Nasdaq rules. The company will file a registration statement with the SEC for the resale of the shares, and the placement is exempt from registration under the Securities Act. Leerink Partners acted as the placement agent.

The most recent analyst rating on (OABI) stock is a Hold with a $2.00 price target. To see the full list of analyst forecasts on OmniAb stock, see the OABI Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 12, 2025