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OmniAb (OABI)
NASDAQ:OABI
US Market
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OmniAb (OABI) AI Stock Analysis

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OABI

OmniAb

(NASDAQ:OABI)

Rating:53Neutral
Price Target:
$2.00
▲(16.96% Upside)
OmniAb's overall stock score reflects significant financial challenges, particularly in profitability and revenue growth, despite a stable balance sheet and improving cash flow. Technical analysis provides mixed signals, while valuation remains unattractive due to ongoing losses. The earnings call highlights potential future growth through partnerships and technology launches, but these are not factored into the score due to weight redistribution.
Positive Factors
Partnership Growth
OmniAb continued to expand its partnered programs, reaching 100 active partners and 381 active programs by the end of 2Q25.
Product Launch
The xPloration platform launched successfully, attracting prospective customers and generating $0.6M shortly after launch, with a 56.9% gross margin viewed as attractive.
Negative Factors
Financial Performance
The company reported revenue of $3.9 million compared to our estimate of $5.4 million and consensus of $5.3 million.
Revenue Decline
Q2 revenues of $3.9M included OABI's first xPloration revenues, but overall revenues declined by 49% year over year.

OmniAb (OABI) vs. SPDR S&P 500 ETF (SPY)

OmniAb Business Overview & Revenue Model

Company DescriptionOmniAb, Inc., a biotechnology company, provides therapeutic antibody discovery technologies in the United States. The company's discovery platform provides industry partners access to the diverse antibody repertoires and screening technologies to enable discovery of next-generation therapeutics. Its OmniAb platform is the biological intelligence of proprietary transgenic animals, including OmniRat, OmniChicken, and OmniMouse that have been genetically modified to generate antibodies with human sequences to facilitate development of human therapeutic candidates. The company's OmniFlic (transgenic rat) and OmniClic (transgenic chicken) address industry needs for bispecific antibody applications though a common light chain approach, and OmniTaur that features unique structural attributes of cow antibodies for complex targets. The company was founded in 2012 and is headquartered in Emeryville, California.
How the Company Makes MoneyOmniAb makes money primarily through licensing agreements and collaborations with pharmaceutical and biotechnology companies. Its revenue model is centered on the use of its proprietary antibody discovery platform, which partners can leverage to develop new therapeutic candidates. Key revenue streams include upfront payments, milestone payments based on the achievement of specific development or regulatory goals, and royalties on sales of drugs developed using OmniAb's technology. Significant partnerships with leading biopharmaceutical companies contribute to its earnings by expanding the reach and application of its platform in the development of innovative therapies.

OmniAb Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 18, 2025
Earnings Call Sentiment Positive
Despite a notable decrease in quarterly revenue and increased net loss, OmniAb showed strong momentum in partnerships and active programs, with high potential future milestones and successful technology launches, suggesting a positive outlook.
Q2-2025 Updates
Positive Updates
Strong Deal Flow and Partnerships
OmniAb added a number of new partners in the first half of 2025, setting a pace for one of their strongest years yet, with the xPloration Partner Access Program receiving a strong market response.
Growth in Active Programs
The number of active programs increased to 381 as of the quarter-end, with a year-to-date net increase of 18 programs, more than doubling the net additions through the first half of 2024.
Significant Milestone Payments Potential
OmniAb's antibody programs have over $3 billion in total remaining contracted potential milestone payments, with an increased average royalty rate of 3.36% from 3.2%.
Advancements in Clinical Programs
A third OmniChicken-derived antibody entered human clinical trials in Q2, with post-discovery stage programs experiencing 22% growth from the prior year period.
xPloration Launch Success
The xPloration system was sold and installed soon after launch, creating a new revenue stream from sales and consumables, with high throughput and positive market feedback.
Negative Updates
Decrease in Quarterly Revenue
Revenue for Q2 2025 was $3.9 million, down from $7.6 million in the same period in 2024, primarily due to lower milestones achieved and service revenue.
Net Loss Increase
The net loss for Q2 2025 was $15.9 million, or $0.15 per share, compared to a net loss of $13.6 million, or $0.13 per share, in the same period in 2024.
Headcount Reductions
OmniAb reduced headcount to 87 employees from 114 at the start of 2025, incurring onetime expenses of about $1 million primarily in the third quarter.
Company Guidance
During the OmniAb Inc. Second Quarter 2025 Financial Results and Business Update Conference Call, the company provided several key metrics and guidance for the remainder of the year. OmniAb reported Q2 revenue of $3.9 million, a decrease from $7.6 million the previous year, primarily due to lower milestone achievements and service revenue. The company's operating expenses decreased to $20.1 million from $23.9 million, with reductions in R&D and G&A expenses. OmniAb maintained its 2025 revenue guidance of $20 million to $25 million and operating expenses between $85 million and $90 million, noting that approximately 40% of these expenses are noncash. The company highlighted its xPloration Partner Access Program, which has begun generating revenue and is expected to diversify its income streams. OmniAb ended Q2 with 100 active partners and 381 active programs, with a year-to-date net increase of 18 programs. The company also reduced its headcount from 114 to 87 employees, anticipating $7 million in annual cash savings. OmniAb's outlook remains on track, with plans to launch new technologies later in the year.

OmniAb Financial Statement Overview

Summary
OmniAb faces significant financial challenges with declining revenue and negative profit margins, although it maintains a strong gross profit margin and a stable balance sheet with low leverage. Cash flow improvements are a positive sign, but operational inefficiencies and revenue growth need addressing.
Income Statement
45
Neutral
OmniAb's income statement reveals significant challenges, with declining revenue and negative profit margins. The TTM data shows a revenue decline of 13.9% and a net profit margin of -275.8%, indicating substantial losses. The EBIT and EBITDA margins are also deeply negative, reflecting operational inefficiencies. However, the gross profit margin remains relatively high at 78.7%, suggesting some potential for cost management improvements.
Balance Sheet
60
Neutral
The balance sheet shows a stable financial structure with a low debt-to-equity ratio of 0.08, indicating conservative leverage. However, the return on equity is negative at -22.8%, highlighting profitability issues. The equity ratio is strong, suggesting a solid asset base relative to liabilities, which provides some financial stability.
Cash Flow
55
Neutral
Cash flow analysis indicates mixed results. The free cash flow has grown by 36.9% in the TTM, showing improvement in cash generation. However, the operating cash flow to net income ratio is 2.28, suggesting cash flow is not yet sufficient to cover net losses. The free cash flow to net income ratio is close to 1, indicating that cash flow is nearly covering net losses, which is a positive sign.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue23.03M26.39M34.16M59.08M34.75M23.27M
Gross Profit18.12M26.39M34.16M42.83M19.78M23.27M
EBITDA-53.25M-50.92M-49.73M-13.01M-19.38M-10.59M
Net Income-63.52M-62.03M-50.62M-22.33M-27.04M-17.56M
Balance Sheet
Total Assets295.67M325.56M375.23M421.21M304.46M295.38M
Cash, Cash Equivalents and Short-Term Investments41.62M59.43M86.98M88.27M-13.85M-2.59M
Total Debt21.78M23.16M25.56M25.80M13.85M2.59M
Total Liabilities33.61M37.94M60.64M79.84M70.16M59.84M
Stockholders Equity262.06M287.62M314.58M341.37M234.31M235.54M
Cash Flow
Free Cash Flow28.28M-41.54M703.00K-20.75M-9.74M1.87M
Operating Cash Flow28.85M-39.66M2.35M-3.59M-5.67M3.62M
Investing Cash Flow16.25M37.88M-18.38M-73.31M-4.03M-26.98M
Financing Cash Flow12.70M13.02M-892.00K110.74M9.70M23.36M

OmniAb Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.71
Price Trends
50DMA
1.89
Negative
100DMA
1.75
Negative
200DMA
2.54
Negative
Market Momentum
MACD
-0.09
Positive
RSI
45.46
Neutral
STOCH
23.53
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OABI, the sentiment is Negative. The current price of 1.71 is below the 20-day moving average (MA) of 1.80, below the 50-day MA of 1.89, and below the 200-day MA of 2.54, indicating a bearish trend. The MACD of -0.09 indicates Positive momentum. The RSI at 45.46 is Neutral, neither overbought nor oversold. The STOCH value of 23.53 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OABI.

OmniAb Risk Analysis

OmniAb disclosed 77 risk factors in its most recent earnings report. OmniAb reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

OmniAb Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$425.97M-12.42%194.98%38.01%
60
Neutral
$578.20M-51.84%-100.00%-25.75%
53
Neutral
$209.82M-22.84%6.05%2.24%
51
Neutral
$7.95B-0.40-41.67%2.21%22.29%-1.85%
44
Neutral
$662.84M-437.92%-78.63%1.88%
42
Neutral
$231.22M-257.38%63.92%
33
Underperform
$274.48M-55.18%60.29%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OABI
OmniAb
1.71
-2.40
-58.39%
VSTM
Verastem
10.77
8.26
329.08%
XOMA
Xoma
35.24
8.14
30.04%
CMPX
Compass Therapeutics
3.44
1.85
116.35%
HUMA
Humacyte
1.43
-3.96
-73.47%
CADL
Candel Therapeutics
5.00
-1.44
-22.36%

OmniAb Corporate Events

Private Placements and FinancingRegulatory Filings and Compliance
OmniAb Announces $30M Private Placement Agreement
Neutral
Aug 25, 2025

On August 24, 2025, OmniAb, Inc. entered into a securities purchase agreement for a private placement of 21,254,106 shares of common stock, expecting to raise approximately $30 million. The proceeds are intended for working capital and general corporate purposes. The private placement is set to close on August 26, 2025, and is conducted in accordance with Nasdaq rules. The company will file a registration statement with the SEC for the resale of the shares, and the placement is exempt from registration under the Securities Act. Leerink Partners acted as the placement agent.

Executive/Board ChangesShareholder Meetings
OmniAb Elects Directors at Annual Shareholder Meeting
Neutral
Jun 18, 2025

OmniAb, Inc. held its 2025 Annual Meeting of Shareholders on June 17, 2025, where shareholders voted on key proposals. During the meeting, two directors, Carolyn R. Bertozzi, Ph.D., and John Higgins, were elected as Class III directors for a three-year term. Additionally, the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2025, was ratified.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 21, 2025