Nucana (NCNA) AI Stock Analysis

• Market Cap: $16.52M
• Dividend Yield: N/A
• Average Volume (3M): 174.33K
• Price to Earnings (P/E): ―
• Beta (1Y): 1.01
• Revenue Growth: N/A
• EPS Growth: 94.52%
• Country: US
• Employees: 20
• Sector: Healthcare
• Sector Strength: 45
• Industry: Biotechnology
• EPS (TTM): 0.00
• Shares Outstanding: 1,906,479
• 10 Day Avg. Volume: 84,221
• 30 Day Avg. Volume: 174,327
• PEG Ratio: 1.57
• Price to Book (P/B): 189.59
• Price to Sales (P/S): 0.00
• P/FCF Ratio: -58.15
• Enterprise Value/Market Cap: -1.01
• Enterprise Value/Revenue: N/A
• Enterprise Value/Gross Profit: N/A
• Enterprise Value/Ebitda: 0.88
• 1Y Price Target: N/A
• Price Target Upside: N/A
• Rating Consensus: N/A
• Number of Analyst Covering: 0
• EPS Forecast (FY): -8
• Revenue Forecast (FY): N/A

• Rating: 28 Underperform
• Price Target: ―

Nucana's overall score is primarily impacted by its financial instability and negative valuation metrics. The significant lack of revenue generation and operational losses are major concerns. Despite showing strong cash management and low leverage, the company's technical indicators suggest a bearish trend, further weighing down the score. The poor valuation metrics, such as a negative P/E ratio, are offset by potential speculative interest due to the low stock price. The absence of notable earnings call insights or corporate events means these factors did not influence the score.

Positive Factors

Proprietary Technology

NuCana's ProTide technology offers a competitive edge by potentially transforming existing chemotherapeutic agents into more effective treatments, which could lead to successful drug development and commercialization.

Cash Management

Strong cash management and low leverage provide financial stability, enabling NuCana to sustain its R&D efforts and navigate the challenges of drug development without immediate financial distress.

Strategic Partnerships

Potential partnerships and collaborations can provide vital funding and resources, enhancing NuCana's ability to advance its drug pipeline and potentially accelerate market entry.

Negative Factors

Lack of Revenue

The absence of revenue generation highlights the risk of financial instability, as the company relies heavily on external funding and successful drug development to achieve future profitability.

Operational Losses

Persistent operational losses without revenue offset strain financial resources, increasing the urgency for successful product development and commercialization to ensure long-term viability.

Equity Decline

Declining equity suggests financial vulnerability, potentially limiting NuCana's ability to raise capital and invest in R&D, which is crucial for advancing its drug pipeline.

Nucana Business Overview & Revenue Model

Company Description

NuCana plc is a clinical-stage biopharmaceutical company focused on developing novel oncology treatment options to improve the lives of patients with cancer. The company is headquartered in Edinburgh, Scotland, and primarily operates in the biotechnology and pharmaceutical sectors. NuCana leverages its proprietary ProTide technology platform to transform chemotherapeutic agents into more effective and safer medicines. Its lead product candidates are currently in various stages of clinical development, targeting a range of cancer types.

How the Company Makes Money

NuCana makes money primarily through the development and commercialization of its proprietary ProTide technology-based drugs. The company's revenue model is focused on advancing its pipeline of product candidates through clinical trials and eventually bringing them to market upon regulatory approval. Additionally, NuCana may generate income through strategic partnerships, licensing agreements, and collaborations with other pharmaceutical companies. These partnerships can provide upfront and milestone payments, as well as royalties on product sales. As a clinical-stage company, NuCana's earnings are currently dependent on its ability to successfully develop and commercialize its drug candidates.

Nucana Financial Statement Overview

Summary

Nucana's financials reflect the challenges faced by biotechnology firms in early development stages, with no revenue generation and consistent losses. While the company demonstrates strong cash management and low leverage, the shrinking equity and continued cash burn highlight financial vulnerabilities. The firm’s financial health would benefit significantly from achieving revenue growth and reducing operational losses.

Income Statement

Nucana's income statement shows no revenue generation over the analyzed period, which is typical for early-stage biotechnology companies. However, the continuous negative EBIT and net income indicate ongoing operational losses without revenue offset.

Balance Sheet

The company's high cash reserves relative to debt showcase prudent cash management, but the consistent decline in stockholders' equity raises concerns. The debt-to-equity ratio remains low, suggesting low financial leverage, yet the reduction in equity suggests potential risks if this trend continues.

Cash Flow

Nucana's cash flow statement reflects substantial negative operating cash flow, indicating cash burn typical of R&D-intensive biotech firms. The company maintains liquidity through financing, but the lack of free cash flow growth suggests an ongoing reliance on external funding.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	0.00	0.00	0.00	0.00	0.00	0.00
Gross Profit	0.00	0.00	0.00	0.00	0.00	0.00
EBITDA	-18.94M	-22.48M	-31.78M	-52.15M	-41.88M	0.00
Net Income	-27.52M	-19.00M	-27.63M	-32.02M	-40.53M	-30.68M
Balance Sheet
Total Assets	32.31M	14.77M	27.81M	58.25M	77.47M	107.79M
Cash, Cash Equivalents and Short-Term Investments	25.25M	6.75M	17.23M	41.91M	60.26M	87.36M
Total Debt	136.00K	190.00K	396.00K	639.00K	371.00K	645.00K
Total Liabilities	6.39M	8.82M	12.92M	19.75M	11.93M	8.56M
Stockholders Equity	25.93M	5.95M	14.89M	38.50M	65.55M	99.23M
Cash Flow
Free Cash Flow	-13.97M	-19.41M	-26.92M	-23.68M	-24.89M	-23.25M
Operating Cash Flow	-13.77M	-19.12M	-26.44M	-23.16M	-23.82M	-21.62M
Investing Cash Flow	47.00K	79.00K	2.89M	120.00K	-3.56M	-1.31M
Financing Cash Flow	27.18M	8.18M	-53.00K	-161.00K	-98.00K	61.80M

Nucana Technical Analysis

• Technical Analysis Sentiment: Neutral
• Last Price: 3.50
• 50DMA: Negative
• 100DMA: Negative
• 200DMA: Negative
• MACD: Negative
• RSI: Neutral
• STOCH: Negative

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NCNA, the sentiment is Neutral. The current price of 3.5 is below the 20-day moving average (MA) of 3.65, below the 50-day MA of 4.28, and below the 200-day MA of 54.06, indicating a neutral trend. The MACD of -0.17 indicates Negative momentum. The RSI at 52.09 is Neutral, neither overbought nor oversold. The STOCH value of 89.86 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for NCNA.

Nucana Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
Sector *	51 Neutral	$7.86B	-0.30	-43.30%	2.27%	22.53%	-2.21%
XBIO	43 Neutral	$6.49M	-1.43	-57.43%	―	13.30%	22.70%
APRE	40 Underperform	$7.89M	-0.58	-74.72%	―	-62.75%	23.87%
IMRN	38 Underperform	$13.59M	-2.96	-49.00%	―	47.17%	26.84%
QLGN	31 Underperform	―	―	-39.69%	―	―	84.34%
GLTO	29 Underperform	$7.87M	-0.44	-114.81%	―	―	37.42%
NCNA	28 Underperform	$16.52M	―	-179.40%	―	―	94.52%