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Mereo Biopharma Group Plc (MREO)
NASDAQ:MREO
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Mereo Biopharma Group Plc (MREO) AI Stock Analysis

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MREO

Mereo Biopharma Group Plc

(NASDAQ:MREO)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
$0.25
▼(-27.35% Downside)
Action:Reiterated
Date:05/14/26
The score is primarily weighed down by weak financial performance (large losses and ongoing cash burn) and bearish technicals (price below key moving averages with negative MACD). Valuation is difficult to assess meaningfully given negative earnings, and corporate events add risk via Nasdaq bid-price noncompliance and potential dilution from renewed share-issuance authority.
Positive Factors
Low Leverage / Balance Sheet Strength
The company’s zero total debt position provides durable financial flexibility for a clinical‑stage biotech. Low leverage reduces bankruptcy and interest burden risk, allowing management to fund R&D and pursue partnerships without near‑term debt servicing constraints.
Negative Factors
Sustained Cash Burn
Persistent operating cash outflows (~$27M TTM) indicate the company consumes material cash to fund development. Over months this requires repeated financing or partnerships; inability to secure funds risks slowing trials, delaying milestones, and increasing dilution for shareholders.
Read all positive and negative factors
Positive Factors
Negative Factors
Low Leverage / Balance Sheet Strength
The company’s zero total debt position provides durable financial flexibility for a clinical‑stage biotech. Low leverage reduces bankruptcy and interest burden risk, allowing management to fund R&D and pursue partnerships without near‑term debt servicing constraints.
Read all positive factors

Mereo Biopharma Group Plc (MREO) vs. SPDR S&P 500 ETF (SPY)

Mereo Biopharma Group Plc Business Overview & Revenue Model

Company Description
Mereo BioPharma Group plc, a biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom and internationally. Its lead product candidate, etigilimab (OMP-313M32), an ant...
How the Company Makes Money
Mereo Biopharma primarily generates revenue through collaboration and licensing arrangements related to its drug development pipeline. These arrangements can include upfront payments, development and regulatory milestone payments, commercial miles...

Mereo Biopharma Group Plc Financial Statement Overview

Summary
Financials are weak overall: revenue remains minimal while net losses are very large and cash burn persists (TTM operating cash outflow ~$27M). The balance sheet is a relative positive with zero total debt, but equity is declining, signaling ongoing financing/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue500.00K500.00K0.0010.00M0.0049.21M
Gross Profit62.51K367.00K0.007.43M257.44K25.04M
EBITDA-39.29M-40.47M-40.80M-26.06M-39.98M25.49M
Net Income-35.70M-41.88M-43.25M-29.47M-42.12M17.17M
Balance Sheet
Total Assets40.61M45.92M76.39M66.50M77.41M170.96M
Cash, Cash Equivalents and Short-Term Investments36.22M40.99M69.80M57.42M68.18M127.52M
Total Debt0.00202.00K6.43M5.95M15.37M22.66M
Total Liabilities6.56M5.00M15.42M15.96M26.01M51.95M
Stockholders Equity34.05M40.92M60.97M50.54M51.40M119.01M
Cash Flow
Free Cash Flow-26.96M-30.99M-33.53M-21.55M-48.83M-7.79M
Operating Cash Flow-26.95M-30.97M-32.83M-21.13M-48.82M-7.07M
Investing Cash Flow-1.52K-20.00K-699.00K-419.00K1.99M-568.20K
Financing Cash Flow-95.27K327.00K46.15M7.97M200.00K104.80M

Mereo Biopharma Group Plc Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.34
Price Trends
50DMA
0.37
Negative
100DMA
0.80
Negative
200DMA
1.34
Negative
Market Momentum
MACD
-0.02
Negative
RSI
45.61
Neutral
STOCH
65.41
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MREO, the sentiment is Neutral. The current price of 0.34 is above the 20-day moving average (MA) of 0.33, below the 50-day MA of 0.37, and below the 200-day MA of 1.34, indicating a neutral trend. The MACD of -0.02 indicates Negative momentum. The RSI at 45.61 is Neutral, neither overbought nor oversold. The STOCH value of 65.41 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for MREO.

Mereo Biopharma Group Plc Risk Analysis

Mereo Biopharma Group Plc disclosed 73 risk factors in its most recent earnings report. Mereo Biopharma Group Plc reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Mereo Biopharma Group Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$886.60M3.391.71%
57
Neutral
$312.90M-3.7153.18%
55
Neutral
$1.67B-12.86-67.52%-100.00%-62.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$377.65M-2.11-61.41%8.16%-434.76%
41
Neutral
$38.55M-1.97-83.02%28.17%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MREO
Mereo Biopharma Group Plc
0.24
-2.00
-89.24%
OMER
Omeros
12.25
9.04
281.03%
VNDA
Vanda
6.28
2.12
50.96%
CAPR
Capricor Therapeutics
28.79
19.35
204.98%
ABEO
Abeona Therapeutics
5.49
-0.61
-10.00%

Mereo Biopharma Group Plc Corporate Events

Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
Mereo BioPharma Shareholders Approve All AGM Resolutions
Positive
May 14, 2026
On May 14, 2026, Mereo BioPharma Group plc held its 2026 Annual General Meeting, at which all proposed resolutions were passed, with 436,766,255 ordinary shares represented in person or by proxy. Shareholders adopted the 2025 annual report and acc...
Executive/Board ChangesShareholder Meetings
Mereo Biopharma Announces Upcoming Board Change, Ensuring Continuity
Neutral
Mar 27, 2026
On March 26, 2026, Mereo BioPharma Group plc disclosed that board member Dr. Annalisa Jenkins has decided not to stand for re-election at the company’s annual general meeting scheduled for May 14, 2026, and will serve out her term until imme...
Delistings and Listing ChangesRegulatory Filings and Compliance
Mereo BioPharma Receives Nasdaq Minimum Bid Price Notice
Negative
Feb 17, 2026
On February 17, 2026, Mereo BioPharma received notice from Nasdaq that its American Depositary Shares had failed to maintain the required minimum bid price of $1.00 for 30 consecutive business days, placing the company out of compliance with Nasda...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026