MBX Biosciences, Inc. (MBX)
NASDAQ:MBX
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MBX Biosciences, Inc.
(NASDAQ:MBX)
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Rating:54Neutral
Price Target:
$33.00
▼(-2.28% Downside)
Action:ReiteratedDate:03/13/26
The score is supported primarily by strong capitalization and positive clinical/regulatory momentum (Phase 3 planning and orphan designations), but it is held back by pre-revenue status with widening losses and rising cash burn, plus weak technicals with the stock trading below key moving averages.
Positive Factors
Balance sheet strength
Very low leverage and materially higher equity/assets provide a durable funding foundation for clinical R&D. This reduces near-term refinancing risk, supports sustained trial investment and partnering optionality, and strengthens negotiating leverage with collaborators.
Negative Factors
Pre-revenue with no commercial sales
Absent product revenue, the business relies entirely on clinical and regulatory milestones to create value. This creates structural uncertainty around commercial traction and cash generation, making long-term sustainability contingent on successful trials or partner deals.
Read all positive and negative factors
Positive Factors
Negative Factors
Balance sheet strength
Very low leverage and materially higher equity/assets provide a durable funding foundation for clinical R&D. This reduces near-term refinancing risk, supports sustained trial investment and partnering optionality, and strengthens negotiating leverage with collaborators.
Read all positive factors
MBX Biosciences, Inc. (MBX) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$1.36B
Dividend YieldN/A
Average Volume (3M)478.03K
Price to Earnings (P/E)―
Beta (1Y)1.96
Revenue GrowthN/A
EPS Growth-30.43%
CountryUS
Employees43
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-0.49
Shares Outstanding47,570,484
10 Day Avg. Volume447,156
30 Day Avg. Volume478,026
Financial Highlights & Ratios
PEG Ratio-0.46
Price to Book (P/B)3.12
Price to Sales (P/S)0.00
P/FCF Ratio-14.06
Enterprise Value/Market Cap0.65
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-5.54K
Enterprise Value/Ebitda-9.28
Forecast
1Y Price Target
$69.20Price Target Upside104.92% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering7
EPS Forecast (FY)-2.83
Revenue Forecast (FY)N/A
MBX Biosciences, Inc. Business Overview & Revenue Model
Company Description
MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is MBX 2109, a parathyroi...
How the Company Makes Money
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MBX Biosciences, Inc. Financial Statement Overview
Summary
Income Statement
12
Very Negative
Balance Sheet
72
Positive
Cash Flow
25
Negative
| Breakdown | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 |
|---|---|---|---|---|
Income Statement | ||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 |
| Gross Profit | -248.00K | 0.00 | 0.00 | 0.00 |
| EBITDA | -98.06M | -67.95M | -35.15M | -25.70M |
| Net Income | -86.97M | -61.92M | -32.56M | -26.14M |
Balance Sheet | ||||
| Total Assets | 385.14M | 268.54M | 84.18M | 45.09M |
| Cash, Cash Equivalents and Short-Term Investments | 373.70M | 262.15M | 80.68M | 42.46M |
| Total Debt | 596.00K | 171.00K | 324.00K | 461.00K |
| Total Liabilities | 15.92M | 11.09M | 156.65M | 87.70M |
| Stockholders Equity | 369.22M | 257.44M | -72.47M | -42.60M |
Cash Flow | ||||
| Free Cash Flow | -81.88M | -55.55M | -32.11M | -23.56M |
| Operating Cash Flow | -79.95M | -54.68M | -31.98M | -23.12M |
| Investing Cash Flow | -83.70M | -160.59M | -30.93M | -11.41M |
| Financing Cash Flow | 189.59M | 234.10M | 69.22M | 46.06M |
MBX Biosciences, Inc. Risk Analysis
MBX Biosciences, Inc. disclosed 92 risk factors in its most recent earnings report. MBX Biosciences, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
MBX Biosciences, Inc. Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
63 Neutral | $6.11B | -39.12 | -20.02% | ― | ― | 8.38% | |
54 Neutral | $1.36B | -13.24 | -28.72% | ― | ― | -30.43% | |
54 Neutral | $1.37B | -37.98 | -444.41% | ― | ― | -13.14% | |
53 Neutral | $1.72B | -5.04 | -64.21% | ― | 27.23% | -12.53% | |
52 Neutral | $2.01B | -13.06 | -41.17% | ― | ― | -33.44% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
41 Neutral | $82.05M | -3.72 | 264.70% | ― | -57.74% | -199.96% |
* Healthcare Sector Average
MBX
MBX Biosciences, Inc.
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172.74%
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TYRA
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228.01%
MBX Biosciences, Inc. Corporate Events
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
MBX Biosciences Advances Canvuparatide After Phase 2 FDA Meeting
Positive
Mar 9, 2026
On March 9, 2026, MBX Biosciences reported that it had successfully completed an End-of-Phase 2 meeting with the U.S. Food and Drug Administration on its once-weekly parathyroid hormone prodrug canvuparatide for chronic hypoparathyroidism. The FDA...
Business Operations and StrategyExecutive/Board Changes
MBX Biosciences Announces CFO Transition and Interim Appointment
Positive
Feb 27, 2026
On February 24, 2026, MBX Biosciences, Inc. signed a lease with 5 Burlington Woods, LLC for about 13,642 square feet of new office and lab space in Burlington, Mass., with a four-year term beginning five months after an expected May 1, 2026 commen...
Business Operations and StrategyPrivate Placements and Financing
MBX Biosciences Raises $87 Million in ATM Offering
Positive
Feb 5, 2026
On February 4, 2026, MBX Biosciences, Inc. closed the sale of 2,250,986 shares of its common stock through its at-the-market offering program at a volume-weighted average price of $38.76 per share, raising approximately $87.1 million in gross proc...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.