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Kezar Life Sciences Inc (KZR)
NASDAQ:KZR

Kezar Life Sciences (KZR) AI Stock Analysis

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KZR

Kezar Life Sciences

(NASDAQ:KZR)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$6.50
▲(5.01% Upside)
Action:ReiteratedDate:12/30/25
The score is held down primarily by weak financial performance (no recent revenue, persistent large losses, and heavy cash burn), with additional pressure from negative corporate developments around regulatory setbacks and restructuring. These risks are partly balanced by improving technical momentum and a low-leverage balance sheet, while valuation support is limited given ongoing losses and no dividend.
Positive Factors
Business Model Strength
Kezar's focus on novel therapies for unmet needs in autoimmune diseases and cancer positions it well in the biotech industry, potentially leading to significant breakthroughs and market opportunities.
Negative Factors
Revenue Generation Challenges
The lack of revenue generation highlights challenges in commercializing products, which could hinder financial sustainability and growth prospects if not addressed.
Read all positive and negative factors
Positive Factors
Negative Factors
Business Model Strength
Kezar's focus on novel therapies for unmet needs in autoimmune diseases and cancer positions it well in the biotech industry, potentially leading to significant breakthroughs and market opportunities.
Read all positive factors

Kezar Life Sciences (KZR) vs. SPDR S&P 500 ETF (SPY)

Kezar Life Sciences Business Overview & Revenue Model

Company Description
Kezar Life Sciences, Inc., a clinical-stage biotechnology company, engages in the discovery and development of novel small molecule therapeutics to treat unmet needs in immune-mediated diseases and cancer in the United States. The company's lead p...
How the Company Makes Money
Kezar Life Sciences generates revenue primarily through strategic partnerships, collaborations, and potential licensing agreements with other pharmaceutical and biotechnology companies. These partnerships may include upfront payments, milestone pa...

Kezar Life Sciences Financial Statement Overview

Summary
Financial fundamentals are weak: revenue is effectively zero in the latest periods, with large ongoing net losses and deeply negative operating/free cash flow indicating continued reliance on external funding. The main offset is low leverage (modest debt), but equity has eroded materially from sustained losses.
Income Statement
18
Very Negative
Balance Sheet
56
Neutral
Cash Flow
24
Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.007.00M0.000.000.00
Gross Profit-478.00K-1.04M7.00M0.00-1.51M-1.54M
EBITDA-59.69M-81.10M-99.25M-66.03M-52.96M-40.26M
Net Income-61.70M-83.74M-101.87M-68.24M-54.63M-41.74M
Balance Sheet
Total Assets97.73M144.68M221.24M299.57M217.93M151.84M
Cash, Cash Equivalents and Short-Term Investments90.22M132.25M201.37M276.56M208.35M140.45M
Total Debt9.91M16.18M18.93M21.26M14.04M5.46M
Total Liabilities14.75M27.77M33.66M29.70M21.06M10.86M
Stockholders Equity82.98M116.92M187.57M269.87M196.88M140.98M
Cash Flow
Free Cash Flow-56.66M-74.24M-83.45M-60.42M-42.75M-37.14M
Operating Cash Flow-56.64M-74.21M-81.64M-58.85M-42.44M-36.95M
Investing Cash Flow64.59M80.43M76.05M-91.39M-28.44M-56.50M
Financing Cash Flow-3.83M103.00K638.00K127.86M112.58M99.64M

Kezar Life Sciences Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price6.19
Price Trends
50DMA
6.50
Negative
100DMA
6.37
Positive
200DMA
5.34
Positive
Market Momentum
MACD
0.02
Positive
RSI
40.48
Neutral
STOCH
10.16
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For KZR, the sentiment is Neutral. The current price of 6.19 is below the 20-day moving average (MA) of 6.87, below the 50-day MA of 6.50, and above the 200-day MA of 5.34, indicating a neutral trend. The MACD of 0.02 indicates Positive momentum. The RSI at 40.48 is Neutral, neither overbought nor oversold. The STOCH value of 10.16 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for KZR.

Kezar Life Sciences Risk Analysis

Kezar Life Sciences disclosed 63 risk factors in its most recent earnings report. Kezar Life Sciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Kezar Life Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$79.20M-2.64-291.42%61.23%
52
Neutral
$46.94M-0.64-62.53%35.80%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
$27.98M-2.65-108.76%-100.00%33.44%
42
Neutral
$4.73M-68.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
KZR
Kezar Life Sciences
6.41
0.77
13.65%
AKTX
Akari Therapeutics
0.14
-1.32
-90.62%
XCUR
Exicure
4.47
-8.80
-66.31%
PYPD
PolyPid
4.08
1.28
45.71%

Kezar Life Sciences Corporate Events

Business Operations and Strategy
Kezar Life Sciences Announces Major Workforce Reduction
Negative
Nov 7, 2025
On November 6, 2025, Kezar Life Sciences announced a restructuring plan that involves reducing its workforce by approximately 70%, equating to about 31 employees. This decision is part of the company’s strategic evaluation of alternatives an...
Business Operations and StrategyPrivate Placements and Financing
Kezar Life Sciences Repays Loan, Ends Agreement
Positive
Oct 22, 2025
On October 20, 2025, Kezar Life Sciences, Inc. fully repaid $6.3 million under its Loan and Security Agreement with Oxford Finance LLC, effectively terminating the agreement and releasing all associated liens and security interests. This financial...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Kezar Life Sciences Faces FDA Challenges in Drug Program
Negative
Oct 16, 2025
On October 16, 2025, Kezar Life Sciences announced a regulatory update regarding its zetomipzomib program for autoimmune hepatitis, revealing challenges in aligning with the FDA on a clinical trial. The FDA’s request for additional studies c...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025