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Purple Biotech Ltd. (IL:PPBT)
:PPBT
Israel Market

Purple Biotech (PPBT) AI Stock Analysis

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IL:PPBT

Purple Biotech

(PPBT)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
1.00
▼(-16.67% Downside)
The score is primarily held down by weak financial performance (pre-revenue, ongoing losses, and negative free cash flow) despite very low leverage. Technicals add further pressure given the stock is below long-term moving averages with negative MACD, while valuation offers limited support due to a negative P/E and no dividend yield data.
Positive Factors
Innovative Drug Platform
The CAPTN-3 platform's promising preclinical results indicate potential for effective cancer treatments, enhancing long-term growth prospects.
Cash Runway
A strong cash position provides financial stability, allowing continued R&D investment and strategic flexibility in the medium term.
Manufacturing Milestone
Reaching manufacturing milestones enhances the company's ability to scale production, supporting future commercialization efforts.
Negative Factors
Pre-Revenue Status
Operating without revenue limits financial self-sufficiency, increasing reliance on external funding and partnerships for sustainability.
Ongoing Cash Burn
Continued cash burn indicates operational inefficiencies and could strain resources, necessitating further capital raising efforts.
Nasdaq Compliance Issue
Non-compliance with Nasdaq listing rules poses a risk of delisting, potentially affecting investor confidence and access to capital markets.

Purple Biotech (PPBT) vs. iShares MSCI Israel ETF (EIS)

Purple Biotech Business Overview & Revenue Model

Company DescriptionPurple Biotech Ltd., a clinical-stage company, focuses on developing therapies to overcome tumor immune evasion and drug resistance for cancer patients in the United States. Its oncology pipeline includes CM24, a humanized monoclonal antibody that blocks carcinoembryonic antigen related cell adhesion molecule 1 as a combination therapy with anti-PD-1 checkpoint inhibitors, which is in Phase 2 clinical trial for the treatment of pancreatic ductal adenocarcinoma; NT219, a small molecule that targets and inhibits insulin receptor substrate 1 and 2, and signal transducer and activator of transcription, which is in Phase 1/2 clinical trials for the treatment recurrent and/or metastatic squamous cell carcinoma of the head and neck cancer or colorectal adenocarcinoma; and IM1240, a multi-valent antibody designed to activate anti-tumoral immune response against 5T4-positive tumors, which is in preclinical stage. The company has collaboration agreement with Bristol Myers Squibb Company for the Phase 2 clinical trials to evaluate the combination of CM24 with the PD-1 inhibitor nivolumab in addition to chemotherapy; and Mor Research Applications. The company was formerly known as Kitov Pharma Ltd and changed its name to Purple Biotech Ltd. in December 2020. The company is headquartered in Rehovot, Israel.
How the Company Makes MoneyPurple Biotech generates revenue primarily through partnerships, licensing agreements, and collaborations with other pharmaceutical companies. These agreements often involve upfront payments, milestone payments based on the achievement of specific development or regulatory milestones, and royalties on sales if the partnered products reach the market. Additionally, the company may receive research grants and funding from governmental and non-governmental organizations to support its R&D activities. Revenue streams are also bolstered by strategic alliances that facilitate the advancement and commercialization of its drug candidates, thereby expanding its market reach and enhancing potential returns on investment.

Purple Biotech Financial Statement Overview

Summary
Purple Biotech faces significant challenges with revenue generation and profitability, as seen in its income statement. The balance sheet reflects a strong equity position but lacks leverage, potentially limiting growth opportunities. Cash flow issues persist, with negative operating and free cash flow impacting financial flexibility. Overall, the company needs to address its revenue generation and operational efficiency to improve its financial health.
Income Statement
Purple Biotech has consistently struggled with generating revenue, with total revenues dropping to zero in most recent years. The company experiences significant net losses, and profit margins are negative, indicating poor profitability. EBIT and EBITDA margins are also negative, showing operational challenges. Historical revenue growth is nonexistent, and the company has not demonstrated an ability to turn around its revenue trajectory.
Balance Sheet
Despite negative net income, Purple Biotech maintains a relatively strong stockholders' equity position due to low total liabilities. The equity ratio remains high, reflecting a strong equity base. However, the debt-to-equity ratio is low, signifying limited leverage, which may constrain growth. The return on equity is negative, indicating inefficiency in generating returns from the equity base.
Cash Flow
The company reports persistent negative operating and free cash flow, indicating poor cash generation from operations. Despite this, Purple Biotech has managed its cash reserves reasonably well, maintaining positive cash balances. The free cash flow to net income ratio is negative, indicating that operations are not supporting profitability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.00195.80K0.000.001.00M
Gross Profit-120.27K-62.00K-196.00-120.00-55.00999.94K
EBITDA-3.55M-7.05M-19.88M-21.49M-17.52M-28.41M
Net Income-3.26M-7.24M-19.88K-21.67M-18.38M-28.00M
Balance Sheet
Total Assets39.06M37.04M44.30M54.62M70.20M83.80M
Cash, Cash Equivalents and Short-Term Investments10.45M8.52M15.41M32.11M47.20M57.80M
Total Debt256.00K183.00K351.00K515.00K749.00K895.00K
Total Liabilities6.25M4.13M10.01M7.52M5.09M4.05M
Stockholders Equity32.77M32.86M34.21M46.91M64.83M79.39M
Cash Flow
Free Cash Flow-5.54M-14.37M-19.93M-16.96M-15.19M-12.25M
Operating Cash Flow-6.54M-14.37M-19.93M-16.73M-15.07M-12.09M
Investing Cash Flow727.13K509.00K13.88M19.91M13.41M-49.59M
Financing Cash Flow10.00M6.77M5.45M1.11M1.51M68.49M

Purple Biotech Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.20
Price Trends
50DMA
1.23
Negative
100DMA
1.62
Negative
200DMA
3.02
Negative
Market Momentum
MACD
-0.02
Positive
RSI
48.35
Neutral
STOCH
50.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IL:PPBT, the sentiment is Negative. The current price of 1.2 is below the 20-day moving average (MA) of 1.21, below the 50-day MA of 1.23, and below the 200-day MA of 3.02, indicating a bearish trend. The MACD of -0.02 indicates Positive momentum. The RSI at 48.35 is Neutral, neither overbought nor oversold. The STOCH value of 50.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for IL:PPBT.

Purple Biotech Risk Analysis

Purple Biotech disclosed 74 risk factors in its most recent earnings report. Purple Biotech reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Purple Biotech Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
17.88M
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
41.77M-1.98-42.69%88.04%
45
Neutral
22.30M-0.6789.32%
42
Neutral
33.60M-1.23-46.97%-127.67%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IL:PPBT
Purple Biotech
1.20
-5.90
-83.10%
IL:XTLB
Xtl Bio
2.20
-4.10
-65.08%
IL:CBI
Clal Biotech
33.20
-2.50
-7.00%
IL:BLRX
Bioline Rx
1.60
-3.60
-69.23%
IL:CANF
Can Fite Bio
682.90
680.90
34045.00%
IL:BOLT
Biolight
371.40
-236.20
-38.87%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025