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BioLineRX Ltd. (IL:BLRX)
:BLRX
Israel Market
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Bioline Rx (BLRX) AI Stock Analysis

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IL:BLRX

Bioline Rx

(BLRX)

Rating:54Neutral
Price Target:
2.50
▼(-3.85%Downside)
The most significant factor contributing to the stock score is the positive sentiment from the earnings call, highlighting strategic milestones and financial stability. However, financial performance remains a challenge due to ongoing profitability and cash flow issues. The technical analysis shows neutral momentum, while the valuation is weakened by negative earnings and lack of dividends.

Bioline Rx (BLRX) vs. iShares MSCI Israel ETF (EIS)

Bioline Rx Business Overview & Revenue Model

Company DescriptionBioLineRx Ltd. is a clinical-stage biopharmaceutical company focused on the development of novel therapeutics to address significant unmet medical needs. The company is primarily engaged in the research and development of drugs in the fields of oncology and immunology. BioLineRx's core products include investigational treatments such as motixafortide, a drug candidate for various types of cancer, and AGI-134, an immunotherapy for solid tumors.
How the Company Makes MoneyBioLineRx makes money primarily through licensing agreements, collaboration arrangements, and milestone payments associated with the development and commercialization of its drug candidates. The company enters into partnerships with larger pharmaceutical companies to co-develop and potentially commercialize its products, allowing it to receive upfront payments, research funding, and milestone-based payments. Additionally, once its products are approved and marketed, BioLineRx may earn royalties on sales. The company also relies on grants and other funding sources to support its research and development activities.

Bioline Rx Earnings Call Summary

Earnings Call Date:May 27, 2025
(Q1-2025)
|
% Change Since: 18.18%|
Next Earnings Date:Aug 13, 2025
Earnings Call Sentiment Positive
The earnings call reflected a positive sentiment with multiple strategic milestones achieved, including successful out-licensing deals and a significant reduction in operating expenses. The company also demonstrated financial stability and progress in clinical trials. However, decreased revenues and potential challenges in regulatory approval for pancreatic cancer were noted as concerns.
Q1-2025 Updates
Positive Updates
Successful Out-Licensing of APHEXDA
BioLineRx entered into an exclusive out-licensing agreement with Ayrmid Pharma Limited for APHEXDA, which is FDA-approved for stem cell mobilization. This agreement includes substantial commercial milestones and royalties.
Significant Reduction in Operating Expenses
BioLineRx reduced its operating cash burn by over 70%, from $40 million annually to less than $12 million, following the restructuring and out-licensing agreement with Ayrmid.
Financial Stability and Strong Cash Position
The company ended the first quarter of 2025 with $26.4 million in cash, a strong financial footing, and a cash runway expected to fund operations through the second half of 2026.
Encouraging APHEXDA Sales
APHEXDA generated $1.4 million in sales in Q1 2025, resulting in $0.3 million in royalty revenues for BioLineRx after returning to growth under Ayrmid's stewardship.
Promising Developments in Pancreatic Cancer Trial
Motixafortide showed a 64% response rate in a pilot study for pancreatic cancer, with new data to be presented at ASCO 2025. This compares favorably to historical response rates.
Negative Updates
Decreased Revenue
Total revenues for the quarter ended March 31, 2025, were $0.3 million compared to $6.9 million for the same period in 2024, primarily due to a decrease in upfront payments and milestone achievements.
Potential Challenges in Regulatory Approval for PDAC
The current pancreatic cancer trial may not lead to regulatory approval due to PFS being the primary endpoint instead of overall survival.
Company Guidance
During the BioLineRx First Quarter 2025 Financial Results Conference Call, Philip Serlin, CEO of BioLineRx, provided detailed guidance on the company's strategic focus and financial position. He highlighted the exclusive out-licensing agreement with Ayrmid Pharma Limited for APHEXDA, an FDA-approved stem cell mobilization agent, which generated $1.4 million in sales in Q1 2025, resulting in $0.3 million in royalty revenue for BioLineRx. The company's operating cash burn was significantly reduced by over 70% to less than $12 million annually, as a result of restructuring efforts, and they ended the quarter with $26.4 million in cash. They are focusing on evaluating early-stage oncology and rare disease assets to expand their pipeline, with potential funding from milestones and royalties from agreements with Ayrmid and Gloria Bio. The company also reported promising developments in ongoing trials, including two Phase 1 trials for sickle cell disease and a Phase 2b pancreatic cancer trial, with interim analysis expected in 2026.

Bioline Rx Financial Statement Overview

Summary
Bioline Rx shows promising revenue growth, but its financial performance is challenged by negative profitability and cash flow issues. High leverage and negative equity returns further emphasize financial instability, posing substantial risks if not addressed.
Income Statement
20
Very Negative
The company showed a significant increase in total revenue from 2023 to 2024, which is a positive sign of growth. However, the net profit margin remains negative due to substantial net losses, indicating ongoing financial challenges. The EBIT and EBITDA margins are also negative, reflecting inefficiencies in operations. Overall, while revenue growth is promising, profitability remains a concern.
Balance Sheet
35
Negative
The debt-to-equity ratio increased, indicating higher leverage, which could be risky. The return on equity remains negative due to net losses, pointing to poor returns for shareholders. The equity ratio has decreased, suggesting reduced financial stability. Although the company has a strong asset base, the increased liabilities and negative equity returns are significant weaknesses.
Cash Flow
25
Negative
The operating cash flow is negative, underscoring cash flow challenges. Free cash flow has also significantly declined, reflecting poor cash management. The operating cash flow to net income ratio is negative, suggesting inefficiencies in converting income into cash. Despite some cash inflows from financing activities, the company struggles to generate positive cash flow, which could hinder its ability to fund operations.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue28.94M4.80M0.000.000.00
Gross Profit19.68M1.11M0.000.000.00
EBITDA3.92M-57.09M-28.50M-24.07M-22.34M
Net Income-9.22M-60.61M-20.75M-28.14M-30.93M
Balance Sheet
Total Assets38.91M63.92M76.38M81.39M47.29M
Cash, Cash Equivalents and Short-Term Investments19.56M42.99M51.08M57.13M22.59M
Total Debt15.04M11.59M12.32M4.65M7.68M
Total Liabilities25.45M50.70M25.54M13.30M25.26M
Stockholders Equity13.46M13.22M50.84M68.09M22.03M
Cash Flow
Free Cash Flow-43.93M-22.91M-26.56M-23.67M-23.21M
Operating Cash Flow-43.87M-22.61M-26.24M-23.57M-23.21M
Investing Cash Flow29.37M1.44M4.01M-38.22M16.67M
Financing Cash Flow20.66M15.06M20.44M57.75M17.87M

Bioline Rx Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.60
Price Trends
50DMA
2.50
Positive
100DMA
2.19
Positive
200DMA
4.74
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
54.23
Neutral
STOCH
55.56
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IL:BLRX, the sentiment is Positive. The current price of 2.6 is above the 20-day moving average (MA) of 2.52, above the 50-day MA of 2.50, and below the 200-day MA of 4.74, indicating a neutral trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 54.23 is Neutral, neither overbought nor oversold. The STOCH value of 55.56 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IL:BLRX.

Bioline Rx Risk Analysis

Bioline Rx disclosed 43 risk factors in its most recent earnings report. Bioline Rx reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Bioline Rx Peers Comparison

Overall Rating
UnderperformOutperform
Sector (60)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
HK$16.84B5.17-7.44%2.89%11.55%-28.15%
54
Neutral
63.94M
90.65%90.80%
42
Neutral
47.80M
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IL:BLRX
Bioline Rx
2.50
-16.80
-87.05%
IL:CANF
Can Fite Bio
1.20
-3.20
-72.73%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 24, 2025