Joint Venture with Hemispherian
BioLineRx established a joint venture with Hemispherian to develop GLIX1, an innovative molecule for glioblastoma treatment. This partnership leverages BioLineRx's clinical and regulatory success with Hemispherian's expertise in DNA damage response research.
GLIX1 Development and Market Potential
GLIX1, a first-in-class oral molecule, targets DNA damage response in cancer cells. The FDA cleared its IND in August, and a Phase I/IIa trial is planned. The glioblastoma market is expected to be over $3.7 billion in the U.S. and Europe by 2030.
Patent Protection for GLIX1
A notice of allowance for a key patent covering GLIX1 was received, extending protection until 2040. Additional patents cover its use alone and in combination with anticancer agents, ensuring broad protection across multiple regions.
Cash Position and Financial Health
BioLineRx ended the third quarter with $25.2 million in cash, sufficient to fund operations into the first half of 2027. This financial stability is bolstered by potential royalties and milestone-driven revenue.
Positive Results for Motixafortide in Sickle Cell Disease
Final positive results for a Phase I trial of motixafortide in sickle cell disease will be presented at the ASH Annual Meeting. The trial demonstrated robust stem cell mobilization and could expand access to curative treatments for these patients.