Strong Revenue Growth
Revenues increased 12% year-over-year to $9.6 billion, driven by strong performance from key growth drivers like Repatha, EVENITY, TEZSPIRE, innovative oncology, rare disease, and biosimilar portfolios.
Record Volume Growth
Volume growth was up 14% year-over-year with 16 products achieving double-digit growth rates; 14 products are now annualizing at over $1 billion in sales.
Significant Advances in Cardiovascular Studies
The Repatha Phase III VESALIUS-CV study met its primary endpoints demonstrating significant reductions in major adverse cardiovascular events in high-risk individuals without prior heart attacks or strokes.
Biosimilar Growth
The biosimilar portfolio delivered a 52% increase in sales year-over-year, now annualizing at $3 billion.
Introduction of AmgenNow
AmgenNow initiative launched to provide direct-to-patient access for Repatha at reduced prices, significantly increasing accessibility for patients.
Debt Reduction and Financial Discipline
Successfully retired $6.0 billion of debt in 2025 and achieved pre-Horizon capital structure ahead of plan.