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QuantumPharm, Inc. (HK:2228)
:2228
Hong Kong Market
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QuantumPharm, Inc. (2228) AI Stock Analysis

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HK:2228

QuantumPharm, Inc.

(2228)

Rating:56Neutral
Price Target:
HK$10.50
▲(2.14% Upside)
QuantumPharm, Inc. receives a moderate score due to strong technical momentum, despite significant financial challenges. The company's inability to generate profits and negative cash flows weigh heavily on its financial performance. While technical indicators suggest bullish trends, overbought conditions may pose risks. Valuation concerns further impact the overall score.
Positive Factors
Financial Strength
The company further strengthened its financial position by completing two fundraising placements raising HK$3.2bn to enhance its cash reserves and fund future growth initiatives.
Partnerships
XtalPi's expanding ecosystem of partnerships reflects its strong commercialization potential across AI and robotics-enabled industries.
Revenue Growth
XtalPi leverages its proprietary AI-powered R&D platform to deliver stable and accelerating revenue growth across two core business areas: drug discovery and intelligent robotics.
Negative Factors
Commercialization Sustainability
Risks relating to R&D progress of drug candidates in partnerships, sustainability of commercialization, and shareholder sell-off.
R&D Pipeline Risks
Risks include potential delays in partnered R&D pipelines, uncertainty in commercialization sustainability, and possible sell-off following lock-up expiry.

QuantumPharm, Inc. (2228) vs. iShares MSCI Hong Kong ETF (EWH)

QuantumPharm, Inc. Business Overview & Revenue Model

Company DescriptionXtalPi Holdings Limited, an investment holding company, provides drug discovery and intelligent automation solutions in China, the United States, Europe, South Korea, and Japan. The company's drug discovery solutions cover the whole drug discovery and research process, including target validation, hit identification, lead generation, lead optimization, and PCC nomination covering various modalities, which comprise small molecules, antibodies, peptides, ADC, and PROTAC. Its intelligent automation solutions focus on AI- and automation-enabled novel drug and materials discovery and research. The company was formerly known as QuantumPharm Inc. and changed its name to XtalPi Holdings Limited in December 2024. XtalPi Holdings Limited was founded in 2015 and is headquartered in Shenzhen, China.
How the Company Makes MoneyQuantumPharm, Inc. generates revenue primarily through the commercialization of its proprietary pharmaceutical products. Key revenue streams include the sale of approved therapeutics, licensing agreements for its advanced drug discovery technologies, and partnerships with pharmaceutical companies for collaborative research and development. Additionally, the company may receive milestone payments and royalties from licensed products developed using its technology platforms. Strategic alliances with research institutions and biotech firms further contribute to its earnings by expanding its technological reach and market presence.

QuantumPharm, Inc. Financial Statement Overview

Summary
QuantumPharm, Inc. shows strong revenue growth, but persistent losses and negative cash flows are concerning. Improvements in debt and equity offer some stability, but profitability and cash flow issues remain critical challenges.
Income Statement
30
Negative
QuantumPharm, Inc. has shown significant revenue growth from 2019 to 2024, yet the company struggles with profitability. Gross Profit Margin improved to 46.31% in 2024 from 27.66% in 2023, but the company continues to incur substantial net losses, with a Net Profit Margin of -569.33% in 2024. The negative EBIT and EBITDA margins highlight ongoing operational challenges.
Balance Sheet
40
Negative
The company has made notable improvements in its balance sheet, reducing total debt significantly from 2023 to 2024. The Debt-to-Equity Ratio has improved due to a positive equity position in 2024. However, the Equity Ratio remains a concern, reflecting potential financial instability.
Cash Flow
35
Negative
Operating Cash Flow has improved slightly, yet remains negative, impacting the company's ability to generate positive Free Cash Flow. Despite the improvement in financing activities, the Free Cash Flow to Net Income Ratio remains unfavorable, indicating ongoing cash flow challenges.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2019
Income Statement
Total Revenue266.43M174.42M133.35M62.80M0.00
Gross Profit123.43M48.24M66.09M32.78M0.00
EBITDA-631.38M-1.78B-390.37M-2.11B-9.84M
Net Income-1.52B-1.91B-1.44B-2.14B-36.03M
Balance Sheet
Total Assets4.35B4.01B4.32B4.38B8.44M
Cash, Cash Equivalents and Short-Term Investments3.10B2.83B3.47B3.83B8.44M
Total Debt148.76M11.04B9.45B7.83B159.05M
Total Liabilities362.43M11.25B9.63B7.99B219.45M
Stockholders Equity3.96B-7.27B-5.33B-3.61B-211.01M
Cash Flow
Free Cash Flow-536.79M-698.20M-627.83M-417.42M655.00K
Operating Cash Flow-478.68M-567.56M-429.10M-253.75M655.00K
Investing Cash Flow74.09M735.58M-2.76B-70.47M33.00K
Financing Cash Flow840.00M-25.89M57.99M2.48B0.00

QuantumPharm, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.28
Price Trends
50DMA
6.78
Positive
100DMA
5.82
Positive
200DMA
5.73
Positive
Market Momentum
MACD
1.07
Negative
RSI
77.28
Negative
STOCH
79.54
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:2228, the sentiment is Positive. The current price of 10.28 is above the 20-day moving average (MA) of 8.23, above the 50-day MA of 6.78, and above the 200-day MA of 5.73, indicating a bullish trend. The MACD of 1.07 indicates Negative momentum. The RSI at 77.28 is Negative, neither overbought nor oversold. The STOCH value of 79.54 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HK:2228.

QuantumPharm, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (56)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
67
Neutral
HK$69.74B48.5519.62%
61
Neutral
7.33-1.60%4.39%30.77%-128.09%
56
Neutral
HK$42.04B
50.10%-212.76%
56
Neutral
$6.56B-0.980.45%6.27%14.92%10.98%
55
Neutral
-64.62%
52
Neutral
HK$18.45B-10.42%
36
Underperform
HK$1.94B-67.27%47.42%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:2228
QuantumPharm, Inc.
10.28
2.13
26.13%
HK:2268
WuXi XDC Cayman, Inc.
54.55
33.90
164.16%
HK:2502
Henan Jinyuan Hydrogenated Chemicals Co., Ltd. Class H
0.50
-0.05
-9.09%
HK:2511
Hightide Therapeutics Inc
3.39
1.91
129.05%
HK:2498
RoboSense Technology Company., Ltd
38.64
27.28
240.14%
HK:2509
Qyuns Therapeutics Co., Ltd. Class H
26.12
4.02
18.19%

QuantumPharm, Inc. Corporate Events

XtalPi Holdings Announces Significant Financial Turnaround in H1 2025
Aug 11, 2025

XtalPi Holdings Limited, a company incorporated in the Cayman Islands, has announced a significant improvement in its financial performance for the first half of 2025. The company expects a substantial increase in revenue and a turnaround from a net loss to a net profit, primarily driven by its collaboration with DoveTree Medicines LLC using its AI drug discovery platform. This marks the first time the company has achieved half-year profits, indicating a positive shift in its operational and financial trajectory.

The most recent analyst rating on (HK:2228) stock is a Buy with a HK$7.57 price target. To see the full list of analyst forecasts on QuantumPharm, Inc. stock, see the HK:2228 Stock Forecast page.

XtalPi and DoveTree Enter Definitive Agreement for AI-Driven Drug Discovery
Aug 5, 2025

XtalPi Holdings Limited, through its subsidiary Shenzhen XtalPi Technology Co., Ltd., has entered into a definitive agreement with DoveTree Medicines LLC to leverage its AI drug discovery platform for developing small molecule and antibody drug candidates. This collaboration focuses on oncology, immunologic and inflammatory diseases, neurological disorders, and metabolic dysregulation, with DoveTree obtaining exclusive development and commercialization rights. The agreement includes an initial payment of $51 million to XtalPi, with potential further payments and royalties based on product sales.

The most recent analyst rating on (HK:2228) stock is a Buy with a HK$7.57 price target. To see the full list of analyst forecasts on QuantumPharm, Inc. stock, see the HK:2228 Stock Forecast page.

XtalPi Partners with DoveTree for AI-Driven Drug Discovery
Jun 22, 2025

XtalPi Holdings Limited has entered into a term sheet with DoveTree LLC to collaborate on drug discovery using its AI and robotics platform. This partnership will focus on developing small molecule and antibody drug candidates for tumors, autoimmune, and neurological diseases, potentially leading to significant financial gains and global commercialization rights for DoveTree.

The most recent analyst rating on (HK:2228) stock is a Buy with a HK$7.57 price target. To see the full list of analyst forecasts on QuantumPharm, Inc. stock, see the HK:2228 Stock Forecast page.

XtalPi Co-Founders Extend Lock-Up, Signaling Confidence
May 26, 2025

XtalPi Holdings Limited, a company incorporated in the Cayman Islands, has announced that its co-founders have voluntarily extended their lock-up undertakings for another year, demonstrating their confidence in the company’s long-term value and future prospects. This extension involves a total of 591,488,405 shares, representing 14.71% of the issued share capital, and is seen as a positive signal for stakeholders, potentially stabilizing the company’s stock and reinforcing its market position.

The most recent analyst rating on (HK:2228) stock is a Buy with a HK$7.57 price target. To see the full list of analyst forecasts on QuantumPharm, Inc. stock, see the HK:2228 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 23, 2025