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QuantumPharm, Inc. (HK:2228)
:2228
Hong Kong Market
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QuantumPharm, Inc. (2228) AI Stock Analysis

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HK:2228

QuantumPharm, Inc.

(2228)

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Neutral 42 (OpenAI - 4o)
Rating:42Neutral
Price Target:
HK$9.50
▲(0.53% Upside)
QuantumPharm, Inc. faces significant financial challenges, with persistent losses and negative cash flows being the most critical issues. The technical analysis suggests weak momentum, further weighing on the stock's outlook. The valuation is unattractive due to a negative P/E ratio and lack of dividend yield. Despite some improvements in debt levels and equity position, the overall financial health remains a concern.
Positive Factors
Revenue Growth
Strong revenue growth indicates successful market penetration and product acceptance, supporting long-term business expansion and competitiveness.
Partnerships
Strategic partnerships expand research capabilities and distribution networks, strengthening market position and fostering innovation.
Gross Profit Margin Improvement
Improved gross profit margin suggests better cost management and pricing power, enhancing long-term profitability potential.
Negative Factors
Persistent Losses
Ongoing losses highlight challenges in achieving profitability, which could hinder long-term financial stability and growth.
Negative Cash Flows
Negative cash flows limit the company's ability to invest in growth opportunities and may necessitate external financing, affecting financial health.
Financial Instability
Concerns about financial instability could impact the company's ability to secure favorable financing terms, affecting long-term operations.

QuantumPharm, Inc. (2228) vs. iShares MSCI Hong Kong ETF (EWH)

QuantumPharm, Inc. Business Overview & Revenue Model

Company DescriptionXtalPi Holdings Limited, an investment holding company, provides drug discovery and intelligent automation solutions in China, the United States, Europe, South Korea, and Japan. The company's drug discovery solutions cover the whole drug discovery and research process, including target validation, hit identification, lead generation, lead optimization, and PCC nomination covering various modalities, which comprise small molecules, antibodies, peptides, ADC, and PROTAC. Its intelligent automation solutions focus on AI- and automation-enabled novel drug and materials discovery and research. The company was formerly known as QuantumPharm Inc. and changed its name to XtalPi Holdings Limited in December 2024. XtalPi Holdings Limited was founded in 2015 and is headquartered in Shenzhen, China.
How the Company Makes MoneyQuantumPharm generates revenue primarily through the commercialization of its pharmaceutical products, which include both proprietary drugs and those developed in collaboration with larger pharmaceutical companies. Key revenue streams include direct sales of approved drugs, licensing agreements for its proprietary technologies, and milestone payments from partnerships for co-development projects. Significant partnerships with major pharmaceutical firms enhance its research capabilities and provide access to broader distribution networks, contributing to its earnings. Additionally, the company may engage in government and private research grants that fund specific projects, further diversifying its revenue sources.

QuantumPharm, Inc. Financial Statement Overview

Summary
QuantumPharm, Inc. shows strong revenue growth but struggles with profitability, as indicated by negative net profit margins and cash flows. Improvements in debt levels and equity position provide some stability, but operational efficiency and financial sustainability remain concerns.
Income Statement
30
Negative
QuantumPharm, Inc. has shown significant revenue growth from 2019 to 2024, yet the company struggles with profitability. Gross Profit Margin improved to 46.31% in 2024 from 27.66% in 2023, but the company continues to incur substantial net losses, with a Net Profit Margin of -569.33% in 2024. The negative EBIT and EBITDA margins highlight ongoing operational challenges.
Balance Sheet
40
Negative
The company has made notable improvements in its balance sheet, reducing total debt significantly from 2023 to 2024. The Debt-to-Equity Ratio has improved due to a positive equity position in 2024. However, the Equity Ratio remains a concern, reflecting potential financial instability.
Cash Flow
35
Negative
Operating Cash Flow has improved slightly, yet remains negative, impacting the company's ability to generate positive Free Cash Flow. Despite the improvement in financing activities, the Free Cash Flow to Net Income Ratio remains unfavorable, indicating ongoing cash flow challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2019
Income Statement
Total Revenue680.88M266.43M174.42M133.35M62.80M0.00
Gross Profit511.39M123.43M48.24M66.09M32.78M0.00
EBITDA-243.20M-631.38M-1.78B-1.38B-2.11B-9.84M
Net Income-196.79M-1.52B-1.91B-1.44B-2.14B-36.03M
Balance Sheet
Total Assets7.72B4.35B4.01B4.32B4.38B8.44M
Cash, Cash Equivalents and Short-Term Investments5.32B3.10B2.83B3.47B3.83B8.44M
Total Debt366.10M148.76M11.04B9.45B7.83B159.05M
Total Liabilities689.47M362.43M11.25B9.63B7.99B219.45M
Stockholders Equity6.99B3.96B-7.27B-5.33B-3.61B-211.01M
Cash Flow
Free Cash Flow-475.64M-536.79M-698.20M-627.83M-417.42M655.00K
Operating Cash Flow-417.87M-478.68M-567.56M-429.10M-253.75M655.00K
Investing Cash Flow-1.69B74.09M735.58M-2.76B-70.47M33.00K
Financing Cash Flow3.13B840.00M-25.89M57.99M2.48B0.00

QuantumPharm, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price9.45
Price Trends
50DMA
11.38
Negative
100DMA
9.96
Negative
200DMA
7.78
Positive
Market Momentum
MACD
-0.48
Positive
RSI
36.38
Neutral
STOCH
20.30
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:2228, the sentiment is Negative. The current price of 9.45 is below the 20-day moving average (MA) of 10.30, below the 50-day MA of 11.38, and above the 200-day MA of 7.78, indicating a neutral trend. The MACD of -0.48 indicates Positive momentum. The RSI at 36.38 is Neutral, neither overbought nor oversold. The STOCH value of 20.30 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:2228.

QuantumPharm, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
73
Outperform
HK$88.15B58.9519.62%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
54
Neutral
HK$710.76M-6.64%2.76%-293.57%
46
Neutral
HK$4.76B-64.62%
42
Neutral
HK$47.27B-171.45-3.55%243.78%97.15%
38
Underperform
HK$15.91B-33.18-11.44%
36
Underperform
HK$1.78B-5.03-67.27%47.42%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:2228
QuantumPharm, Inc.
9.45
4.76
101.49%
HK:2268
WuXi XDC Cayman, Inc.
67.50
35.75
112.60%
HK:2502
Henan Jinyuan Hydrogenated Chemicals Co., Ltd. Class H
0.44
-0.07
-13.73%
HK:2511
Hightide Therapeutics Inc
3.00
2.03
209.28%
HK:2498
RoboSense Technology Company., Ltd
32.86
4.61
16.32%
HK:2509
Qyuns Therapeutics Co., Ltd. Class H
20.96
9.98
90.89%

QuantumPharm, Inc. Corporate Events

XtalPi Enters Consumer Healthcare with AI-Developed Hair Growth Molecules
Nov 10, 2025

XtalPi Holdings Limited has announced the successful development of two new molecules, Remeanagen™ and AquaKine™, for hair growth and hair loss prevention using its AI molecular discovery platform. These molecules, combined in the product Groland, have shown superior performance in human trials and received key international certifications, marking XtalPi’s entry into the consumer healthcare sector. This development underscores the company’s commitment to leveraging AI for creating both life-saving drugs and consumer products that enhance daily life.

XtalPi’s Ailux Partners with Eli Lilly for AI-Driven Antibody Development
Nov 5, 2025

XtalPi’s subsidiary, Ailux, has announced a strategic collaboration with Eli Lilly to enhance the development of bispecific antibodies using AI-driven technology. This partnership allows Lilly to access Ailux’s advanced antibody engineering platform, potentially leading to significant milestone payments and a total collaboration value of up to $345 million, marking a substantial impact on XtalPi’s industry positioning and stakeholder interests.

XtalPi Holdings Clarifies Interim Results, Corrects Earnings Figures
Sep 16, 2025

XtalPi Holdings Limited, a company listed on the Hong Kong Stock Exchange, issued a clarification announcement regarding its interim results for the six months ended June 30, 2025. The company corrected errors in the reported number of ordinary shares and earnings per share figures, which were initially misstated in their interim results announcement. The corrected figures indicate a higher earnings per share than previously reported, which may positively impact stakeholders’ perception of the company’s financial performance.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 21, 2025