Advancement of GLPG5101 CD19 CAR-T Program
Galapagos made significant progress in advancing their flagship GLPG5101 CD19 CAR-T clinical development program, receiving FDA's IND clearance to begin clinical studies in the U.S. The program showed promising results in the ATALANTA study, with high overall and complete response rates in refractory/relapsed lymphomas.
Strategic Partnerships and Collaborations
Galapagos executed key partnerships with companies like Lonza, Thermo Fisher, and Adaptimmune to support their cell therapy goals. These partnerships aim to enhance their decentralized manufacturing platform and expand therapeutic applications.
Separation into Two Entities
Galapagos announced plans to separate into two publicly-traded entities, Galapagos and SpinCo. SpinCo will focus on building a pipeline of innovative medicines through transformational transactions, while Galapagos will concentrate on accelerating global oncology leadership.
Financial Performance and Cash Position
Galapagos reported a net profit of €74 million for 2024, driven by fair value adjustments, currency exchange, and interest income. The company ended the year with approximately €3.3 billion in cash.