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Glaukos (GKOS)
NYSE:GKOS
Sham Procedure, Gen 2 Travoprost Intracameral Implant, Timolol Eye Drops 0.5%
Glaucoma
Phase II/III
Recruiting
Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Jul 10, 2025
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Idose Tr (Travoprost Intracameral Implant) 75 Μg In Conjunction With Cataract Surgery, Sham Procedure In Conjunction With Cataract Surgery
Glaucoma, Open-Angle, Ocular Hypertension (Oht), Phacoemulsification Cataract Surgery
Phase IV
Recruiting
Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
Feb 01, 2025
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Vehicle, Lufepirsen High Dose, Lufepirsen Low Dose
Persistent Corneal Epithelial Defect
Phase II
Recruiting
A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED
Jun 20, 2023
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Vehicle, Nexagon® (Lufepirsen) High Dose Concentration, Nexagon® (Lufepirsen) Low Dose Concentration, Open-Label Nexagon® (Lufepirsen)
Corneal Persistent Epithelial Defect
Phase II
Terminated
NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular Injuries
Aug 29, 2019
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G2-Tr Intraocular Implant Containing Travoprost, Sham Surgery + Active-Comparator Eye Drops
Ocular Hypertension, Glaucoma, Open-Angle
Phase III
Completed
Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Mar 06, 2019
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G2-Tr Intraocular Implant Containing Travoprost, Sham Surgery + Active-Comparator Eye Drops
Ocular Hypertension, Glaucoma, Open-Angle
Phase III
Completed
Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%
Apr 26, 2018
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Glaukos (GKOS) have in its pipeline
GKOS is currently developing the following drugs: Sham Procedure, Gen 2 Travoprost Intracameral Implant, Timolol Eye Drops 0.5%, Idose Tr (Travoprost Intracameral Implant) 75 Μg In Conjunction With Cataract Surgery, Sham Procedure In Conjunction With Cataract Surgery, Vehicle, Lufepirsen High Dose, Lufepirsen Low Dose. These drug candidates are in various stages of clinical development as the company works toward FDA approval.