tiprankstipranks
Trending News
More News >
Tissue Regenix Group PLC (GB:TRX)
LSE:TRX
Advertisement

Tissue Regenix (TRX) AI Stock Analysis

Compare
15 Followers

Top Page

GB:TRX

Tissue Regenix

(LSE:TRX)

Select Model
Select Model
Select Model
Neutral 51 (OpenAI - 4o)
Rating:51Neutral
Price Target:
8.00p
▲(10.34% Upside)
The overall stock score is primarily influenced by financial performance, which shows some operational improvements but significant challenges remain. Technical analysis indicates bearish momentum, and valuation metrics reflect ongoing financial struggles. The earnings call provided some positive insights, but these were outweighed by revenue declines and regulatory issues.

Tissue Regenix (TRX) vs. iShares MSCI United Kingdom ETF (EWC)

Tissue Regenix Business Overview & Revenue Model

Company DescriptionTissue Regenix Group plc, a medical technology company, develops and commercializes platform technologies in the field of tissue engineering and regenerative medicine in the United States and internationally. It operates through BioSurgery, Orthopaedics & Dental, and GBM-V & Cardiac divisions. The company provides dCELL technology, a soft tissue decellularisation process that removes DNA and cellular material from animal and human soft tissue to repair diseased or damaged body parts; and BioRinse technology, a natural bone filler solution for osteoinductive to stimulate and regenerate native bone growth. In addition, the company provides DermaPure, a decellularised dermal allograft for reinforcement, repair, and replacement of damaged or inadequate integumental tissue and other homologous uses of human integument; and SurgiPure XD, Decellularised porcine dermal reconstructive tissue matrix for the repair of hernias and body wall defects. Further, it offers OrthoPure XT, a scaffold to replace the damaged tissue that will re-populate with the patient's own cells; ConCelltrate 100, a verified osteoinductive bone matrix; MatrixCellect 100, a demineralised bone matrix (DBM) for orthopaedic; Matrix IQ Dermis, a human-derived dermal graft, which is decellularised to remove cellular components and preserve the biological properties that promote revascularisation, repair, and augmentation of damaged tissue; and Matrix OI FlexIt, a thin pliable demineralised cortical allograft bone sheet. Additionally, the company provides DentalFix, a mineralized particulate allograft that offer osteoconductive properties of natural bone; CardioPure products; Matrix OI 100 DBM for non-structural bone-grafting; Matrix OI Strips and Blocks, a stem cell containment human scaffold; AmnioWorks for ophthalmology and wound covering; and sports medicine products. The company was incorporated in 2006 and is based in Garforth, the United Kingdom.
How the Company Makes MoneyTissue Regenix generates revenue through the sale of its regenerative tissue products, which are used in various surgical procedures. The company's key revenue streams include the commercialization of its OrthoPure and DermaPure product lines, which are designed for orthopedic and wound care applications, respectively. Additionally, TRX engages in partnerships and collaborations with healthcare providers and institutions to expand its market reach and product offerings. These relationships often involve licensing agreements, joint ventures, and distribution contracts, contributing to the company's overall earnings. The growing demand for innovative tissue regeneration solutions and the increasing prevalence of chronic wounds and orthopedic conditions further bolster TRX's revenue generation capabilities.

Tissue Regenix Earnings Call Summary

Earnings Call Date:Sep 30, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Jun 04, 2026
Earnings Call Sentiment Negative
The earnings call highlighted several positive developments, such as growth in specific product lines, new patents, and certifications. However, these were overshadowed by significant revenue declines, issues with regulatory approvals, and financial challenges. While there are strategic efforts underway to address these issues, the current financial and operational setbacks present substantial challenges.
Q2-2025 Updates
Positive Updates
Growth in dCELL Business
Despite challenges, the dCELL business grew by 10% year-over-year in H1 2025.
EU Patent and MDR Certification
Received an EU patent for the dCELL process and MDR certification, securing IP protection and compliance with new medical device regulations.
Increase in Demineralized Bone Matrix Orders
Orders for demineralized bone matrix products increased by 4% in H1 2025.
Publication of OrthoPure XT Clinical Results
The 5-year clinical results of OrthoPure XT were published in the Journal of Experimental Orthopaedics.
Negative Updates
Revenue Decline
Group revenues were down 6% in H1 2025 compared to H1 2024, with the BioRinse business down 7% and dCELL business down 4%.
Decrease in Gross Profit
Gross profit decreased due to lower yields from donor tissue and increased inventory costs.
Impact of CFG Delays
Delays in Certificates of Foreign Government impacted regulatory approvals, leading to a 45% decrease in the RDT business.
Decline in Strategic Partner Orders
Orders from a specific strategic partner decreased by 37% in H1 2025.
Increased Financial Strain
Decreased revenues and gross profit led to reduced EBITDA and increased reliance on revolving credit.
Company Guidance
During the investor presentation call for Tissue Regenix Group plc, the management team, including Executive Chairman Jay LeCoque, Chief Executive Officer Daniel Lee, and Interim Chief Financial Officer Brandon Largent, provided an overview of the company's financial performance and strategic initiatives. The company reported a 6% decline in group revenues for the first half of 2025 compared to the previous year, with the U.S.-based BioRinse business down 7% and the dCELL business down 4%. Despite these downturns, orders for demineralized bone matrix products increased by 4%, and the dCELL direct business grew by 10%. Gross profit decreased due to lower production yields and increased inventory costs, while adjusted EBITDA also fell year-over-year. The team highlighted significant advancements, such as receiving an EU patent for the dCELL process and MDR certification for the OrthoPure XT product. They also addressed issues related to delays in obtaining Certificates of Foreign Governments from the FDA, impacting the release donor tissue business, which saw a 45% decrease. The management team emphasized their commitment to strengthening the company's commercial approach, reviewing cost structures, and expanding geographically, despite current regulatory headwinds, to ensure sustainable long-term growth.

Tissue Regenix Financial Statement Overview

Summary
Tissue Regenix shows operational improvements with better gross margins and reduced operating losses. However, persistent net losses and negative cash flows highlight challenges in achieving profitability. The strong equity base provides stability, but increased leverage and reliance on external funding pose risks.
Income Statement
62
Positive
The company has shown improvement in its gross profit margin, increasing from previous years, indicating better cost management. However, the net profit margin remains negative, reflecting ongoing challenges in achieving profitability. Revenue growth has been inconsistent, with fluctuations observed over the years. While the EBIT and EBITDA margins have improved, they remain low, highlighting the need for further operational efficiencies.
Balance Sheet
68
Positive
The company maintains a strong equity base, with a healthy equity ratio, suggesting financial stability. However, the debt-to-equity ratio has increased, indicating higher leverage, which could pose risks if not managed carefully. Return on equity remains negative due to net losses, underscoring the need for improved profitability to enhance shareholder value.
Cash Flow
55
Neutral
Cash flow from operations has been negative, impacting the company's ability to internally fund its activities. The free cash flow remains negative, highlighting potential liquidity constraints. The company has relied on financing activities to support its cash position, which could be unsustainable in the long term if operating cash flows do not improve.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue17.49M28.65M29.49M24.48M19.75M12.83M
Gross Profit9.31M13.62M14.04M9.14M5.63M5.13M
EBITDA1.06M1.36M446.00K-1.04M-3.04M-9.03M
Net Income-865.40K-713.00K-1.71M-2.69M-4.79M-9.71M
Balance Sheet
Total Assets45.12M45.35M43.24M38.27M34.13M36.73M
Cash, Cash Equivalents and Short-Term Investments3.46M1.87M4.65M4.95M5.69M9.55M
Total Debt10.47M10.46M9.39M9.61M7.95M7.22M
Total Liabilities15.78M16.29M13.89M13.00M9.47M8.88M
Stockholders Equity30.04M29.82M30.15M31.25M25.35M28.46M
Cash Flow
Free Cash Flow-361.44K-5.70M177.00K-2.29M-3.93M-6.84M
Operating Cash Flow-1.33K-1.64M1.04M-1.41M-2.45M-5.47M
Investing Cash Flow-605.68K-4.06M-837.00K-1.08M-2.04M-1.86M
Financing Cash Flow306.50K3.28M-1.51M910.00K-192.00K17.68M

Tissue Regenix Technical Analysis

Technical Analysis Sentiment
Negative
Last Price7.25
Price Trends
50DMA
18.94
Negative
100DMA
25.11
Negative
200DMA
33.60
Negative
Market Momentum
MACD
-3.41
Negative
RSI
12.03
Positive
STOCH
55.72
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:TRX, the sentiment is Negative. The current price of 7.25 is below the 20-day moving average (MA) of 8.56, below the 50-day MA of 18.94, and below the 200-day MA of 33.60, indicating a bearish trend. The MACD of -3.41 indicates Negative momentum. The RSI at 12.03 is Positive, neither overbought nor oversold. The STOCH value of 55.72 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:TRX.

Tissue Regenix Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$7.86B-0.30-43.30%2.27%22.53%-2.21%
£5.16M-4.90-5.41%-20.31%-19.35%
£18.64M-5.63-101.07%45.70%
£27.00M-204.29%3.31%21.91%
£6.36M-0.11-333.59%45.22%55.71%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:TRX
Tissue Regenix
7.25
-52.25
-87.82%
GB:FUM
Futura Medical
2.88
-33.60
-92.11%
GB:IMM
ImmuPharma
10.95
9.36
588.68%
GB:OBD
Oxford BioDynamics
0.32
-0.82
-71.93%
GB:SAR
Sareum Holdings
13.50
-11.50
-46.00%
GB:AREC
Arecor Therapeutics PLC
71.50
-3.50
-4.67%

Tissue Regenix Corporate Events

Delistings and Listing ChangesFinancial Disclosures
Tissue Regenix Suspends Trading to Address Financial Review
Negative
Oct 22, 2025

Tissue Regenix has temporarily suspended trading of its shares on AIM to allow its new leadership team to review and address financial discrepancies related to the restatement of revenue numbers for the fiscal year 2024. The company is implementing strict financial controls and aims to reduce costs by over $2 million, with a commitment to business recovery and sustainable growth.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £8.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Tissue Regenix Strengthens Leadership with New Board Appointment
Positive
Oct 17, 2025

Tissue Regenix has announced that Kirsten Lund, the Chief Financial Officer, has joined the company’s board with immediate effect. This move is part of the company’s strategic efforts to strengthen its leadership team, potentially enhancing its operational efficiency and market positioning in the regenerative medical devices industry.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £8.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
Tissue Regenix Announces Financial Restatement and Leadership Changes
Negative
Oct 16, 2025

Tissue Regenix announced significant financial and organizational changes, including a restatement of FY24 adjusted EBITDA from a profit to a loss and the departure of CEO Daniel Lee. The company has appointed Jay LeCoque as Acting CEO and Executive Chairman and reappointed Kirsten Lund as CFO to implement strict financial controls and a cost reduction initiative. These changes aim to improve financial performance and expand the company’s market presence, with a focus on sustainable, long-term growth.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £8.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Tissue Regenix Faces Challenges Amid Growth and Setbacks
Oct 10, 2025

The recent earnings call for Tissue Regenix presented a mixed sentiment, with some positive developments overshadowed by significant financial challenges. While there were notable achievements in product growth and regulatory advancements, the company faces substantial hurdles due to revenue declines and operational setbacks. The management expressed strategic efforts to address these issues, but the current financial landscape remains challenging.

Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
Tissue Regenix Reports Revenue Decline Amid Regulatory Challenges
Negative
Sep 30, 2025

Tissue Regenix Group PLC reported a 6% decrease in revenue for the first half of 2025, primarily due to commercial, regulatory, and reimbursement challenges. Despite a downturn in trading and a reduced cash position, the company remains optimistic about its long-term growth prospects, supported by recent certifications and patents, as well as an expanded distribution network. Management changes and strategic focus on sustainable revenue opportunities aim to enhance shareholder value.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £25.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresRegulatory Filings and Compliance
Tissue Regenix Faces Revenue Decline Amid Regulatory Challenges
Neutral
Sep 30, 2025

Tissue Regenix Group reported a 6% revenue decline for the first half of 2025, attributed to commercial, regulatory, and reimbursement challenges. The company’s BioRinse® and dCELL® product lines faced revenue decreases, while the gross profit margin fell to 42% due to lower production yields. Despite these setbacks, the company received CE certification for OrthoPure® XT and a European patent for dCELL® technology, and expanded its dCELL distribution network. Management changes were also announced, with new appointments and resignations. The company remains optimistic about future growth and aims to improve trading and cash flow in the long term.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £25.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Financial Disclosures
Tissue Regenix to Release Interim Results with Investor Presentation
Neutral
Sep 17, 2025

Tissue Regenix announced that it will release its interim results on 30 September 2025, with a live online presentation hosted by the CEO and Executive Chairman. This event is open to current and potential shareholders, indicating the company’s commitment to transparency and engagement with its stakeholders.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £25.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Tissue Regenix Appoints Jay LeCoque as Executive Chairman Amid Board Reshuffle
Positive
Sep 8, 2025

Tissue Regenix has announced significant changes to its Board of Directors, with Jay LeCoque appointed as the new Executive Chairman. LeCoque brings over 25 years of experience in senior management within the life sciences sector, which is expected to strengthen the company’s growth and earnings. The resignations of Jonathan Glenn and Trevor Phillips from the Board were also announced, with the company expressing gratitude for their contributions. The appointment of LeCoque is seen as a strategic move to enhance the company’s position in the global healthcare and clinical life sciences market.

The most recent analyst rating on (GB:TRX) stock is a Hold with a £30.00 price target. To see the full list of analyst forecasts on Tissue Regenix stock, see the GB:TRX Stock Forecast page.

Executive/Board Changes
Tissue Regenix Announces Leadership Transition with New Interim CFO
Neutral
Aug 1, 2025

Tissue Regenix has announced a change in its leadership team with the retirement of Chief Financial Officer David Cocke. Brandon Largent, who has extensive experience in financial operations, will take over as Interim CFO. This transition is expected to be seamless, leveraging Brandon’s familiarity with the company and his previous leadership roles. The change reflects the company’s ongoing commitment to maintaining strong financial leadership as it continues to grow and innovate in the regenerative medical devices sector.

Business Operations and StrategyShareholder Meetings
Tissue Regenix Secures Strong Shareholder Support at AGM
Positive
Jul 23, 2025

Tissue Regenix announced that all resolutions were passed at their Annual General Meeting, with a significant majority of votes in favor. This outcome reflects strong shareholder support and positions the company well for future strategic initiatives, reinforcing its standing in the regenerative medical devices industry.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 11, 2025