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Syncona Shs GBP (GB:SYNC)
LSE:SYNC
UK Market

Syncona Shs GBP (SYNC) AI Stock Analysis

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Syncona Shs GBP

(LSE:SYNC)

65Neutral
Syncona Shs GBP exhibits financial stability with a solid balance sheet and improved cash flow. However, revenue volatility and negative valuation metrics are significant challenges. The technical indicators suggest bearish trends, but the strategic share buyback program provides some positive momentum. Despite these strengths, valuation concerns and market challenges contribute to a mixed outlook.

Syncona Shs GBP (SYNC) vs. S&P 500 (SPY)

Syncona Shs GBP Business Overview & Revenue Model

Company DescriptionSyncona Limited is a leading healthcare company focused on investing in life sciences with the aim of creating, building, and scaling global leaders in innovative therapeutics. Operating primarily in the biotechnology and pharmaceuticals sectors, Syncona's core activities involve identifying and nurturing high-potential healthcare businesses, particularly in areas with significant unmet medical needs.
How the Company Makes MoneySyncona makes money by investing in and managing a portfolio of life sciences companies. The company's revenue model primarily involves generating returns from its investments in these companies, either through exits such as public offerings or acquisitions, or through the appreciation of its equity stakes. Syncona often takes a long-term approach, providing capital and strategic guidance to help these businesses grow and reach significant value milestones. Key revenue streams include realized gains from the sale of investments, dividends from successful portfolio companies, and potential royalties or milestone payments from partnerships. The company's strategy is supported by its expertise in the life sciences sector and its commitment to building sustainable businesses that can achieve commercial success.

Syncona Shs GBP Financial Statement Overview

Summary
Syncona Shs GBP demonstrates a mixed financial performance, with strengths in its balance sheet stability and recent improvements in cash flow generation. However, the income statement reveals revenue volatility, which poses a challenge for consistent profitability. The company's robust equity and zero-debt position provide resilience, while improved cash flows enhance operational flexibility.
Income Statement
65
Positive
The company's revenue has shown significant volatility, with a recent return to positive figures in 2024 after negative in 2023. Gross profit margin improved to 45.89% in 2024, and net profit margin turned positive at 12.32%. However, the revenue growth trajectory remains unstable, reflecting a challenging market environment.
Balance Sheet
78
Positive
Syncona Shs GBP maintains a strong balance sheet with zero debt, resulting in a solid Debt-to-Equity ratio of 0. The equity ratio is robust at 99.02%, indicating financial stability and minimal leverage risk. The company is well-capitalized, supporting its long-term sustainability.
Cash Flow
72
Positive
The operating cash flow has significantly improved to £20.47M in 2024, translating into a strong free cash flow. The operating cash flow to net income ratio is 5.40, indicating efficient cash generation relative to its profitability. The cash flow position has stabilized, reflecting better cash management strategies.
Breakdown
Mar 2024Mar 2023Mar 2022Mar 2021Mar 2020
Income StatementTotal Revenue
30.75M-39.79M18.69M78.54M-167.31M
Gross Profit
14.10M-51.91M3.68M78.54M-174.82M
EBIT
8.14M-51.38M13.09M57.87M-190.95M
EBITDA
3.79M0.00-1.94M0.00-1.91M
Net Income Common Stockholders
3.79M-56.02M8.84M53.16M-195.56M
Balance SheetCash, Cash Equivalents and Short-Term Investments
261.00K11.00K276.00K14.00K17.00K
Total Assets
1.25B1.27B1.33B1.34B1.28B
Total Debt
0.000.000.000.000.00
Net Debt
-261.00K-11.00K-276.00K-14.00K-17.00K
Total Liabilities
12.22M13.76M23.55M38.12M30.31M
Stockholders Equity
1.24B1.25B1.31B1.30B1.25B
Cash FlowFree Cash Flow
20.47M-265.00K262.00K-3.00K13.17M
Operating Cash Flow
20.47M-265.00K262.00K-3.00K13.17M
Investing Cash Flow
0.000.000.000.000.00
Financing Cash Flow
-20.22M0.000.000.00-13.25M

Syncona Shs GBP Technical Analysis

Technical Analysis Sentiment
Negative
Last Price90.00
Price Trends
50DMA
90.28
Negative
100DMA
93.73
Negative
200DMA
103.21
Negative
Market Momentum
MACD
0.65
Negative
RSI
51.47
Neutral
STOCH
46.51
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:SYNC, the sentiment is Negative. The current price of 90 is above the 20-day moving average (MA) of 88.06, below the 50-day MA of 90.28, and below the 200-day MA of 103.21, indicating a neutral trend. The MACD of 0.65 indicates Negative momentum. The RSI at 51.47 is Neutral, neither overbought nor oversold. The STOCH value of 46.51 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:SYNC.

Syncona Shs GBP Peers Comparison

Overall Rating
UnderperformOutperform
Sector (64)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
GBAZN
79
Outperform
£166.76B27.2719.90%2.28%13.74%21.45%
GBGSK
71
Outperform
£58.60B18.7622.52%4.21%2.57%-30.13%
GBEKF
67
Neutral
£94.78M15.228.95%5.71%-4.59%165.38%
65
Neutral
-1.50%209.37%87.77%
64
Neutral
$12.64B9.748.05%17044.60%12.66%-4.62%
63
Neutral
HK$20.92B71.055.02%-25.07%-64.03%
GBOXB
52
Neutral
$312.70M-66.23%43.84%74.88%
* Financial Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:SYNC
Syncona Shs GBP
90.00
-32.00
-26.23%
GB:OXB
Oxford BioMedica
295.00
-21.00
-6.65%
GB:EKF
EKF Diagnostics Holdings
21.00
-8.00
-27.59%
GB:AZN
AstraZeneca
10,754.00
-1,117.02
-9.41%
GB:GSK
GlaxoSmithKline
1,448.50
-243.43
-14.39%
HK:0013
HUTCHMED (China)
24.00
-7.90
-24.76%

Syncona Shs GBP Corporate Events

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback Program
Positive
May 2, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 of its ordinary shares at a price of 90.90 GBp each. These shares will be held in treasury, affecting the total voting rights in the company, which now stand at 612,794,565. This move is part of Syncona’s strategy to manage its share capital effectively and potentially enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

The overall score for Syncona Shs GBP reflects a robust financial foundation and strong balance sheet, offset by revenue volatility and negative valuation metrics. While the technical indicators show bearish trends, the company’s strategic buyback program offers positive momentum. Despite these strengths, market challenges and valuation concerns remain significant, impacting the overall stock score.

To see Spark’s full report on GB:SYNC stock, click here.

Regulatory Filings and Compliance
Syncona Limited Updates Total Voting Rights and Share Issuance
Neutral
May 1, 2025

Syncona Limited announced that as of April 30, 2025, it has 672,214,632 ordinary shares issued, with 59,270,067 held in treasury, resulting in 612,944,565 voting rights. This figure is crucial for shareholders to determine their notification requirements under the FCA’s rules. The announcement underscores Syncona’s commitment to transparency and regulatory compliance, which is vital for maintaining investor confidence and ensuring accurate shareholder reporting.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s strong financial stability and strategic corporate actions are offset by revenue volatility, bearish technical trends, and negative valuation metrics. The company’s zero-debt position and capital management strategies, including share buybacks, enhance resilience and shareholder value, but market challenges and profitability concerns remain significant.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
May 1, 2025

Syncona Limited announced the repurchase of 150,000 of its ordinary shares as part of its ongoing share buyback program. The shares were bought at a price of 91.8189 GBp each and will be held in treasury, reducing the total voting rights to 612,944,565. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value, reflecting its commitment to delivering strong risk-adjusted returns.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s strong financial stability and strategic corporate actions are offset by revenue volatility, bearish technical trends, and negative valuation metrics. The company’s zero-debt position and capital management strategies, including share buybacks, enhance resilience and shareholder value, but market challenges and profitability concerns remain significant.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Neutral
Apr 30, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its share buyback programme, with the shares to be held in treasury. This transaction impacts the company’s total voting rights, which now stand at 613,094,565, and is part of Syncona’s strategy to manage its capital structure effectively while focusing on long-term returns and stakeholder benefits.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s strong financial stability and strategic corporate actions are offset by revenue volatility, bearish technical trends, and negative valuation metrics. The company’s zero-debt position and capital management strategies, including share buybacks, enhance resilience and shareholder value, but market challenges and profitability concerns remain significant.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Strategic Share Buyback
Positive
Apr 29, 2025

Syncona Limited has executed a share buyback, purchasing 100,000 of its ordinary shares at a consistent price of 92.8676 GBp per share, as part of its ongoing Share Buyback Programme. This transaction reduces the total voting rights to 613,244,565, potentially impacting shareholder calculations under FCA rules. The repurchased shares will be held in treasury, reflecting Syncona’s strategic financial management to enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP exhibits strong financial stability, with a robust balance sheet and improved cash flows. However, revenue volatility and negative valuation metrics present significant challenges. The technical indicators suggest bearish trends, but the strategic share buyback program offers positive momentum. Overall, the stock’s potential is offset by market and valuation concerns.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Optimize Capital Structure
Positive
Apr 28, 2025

Syncona Limited has executed a share buyback program, purchasing 90,000 of its own ordinary shares at a volume-weighted average price of 91.7540 GBp per share. These shares will be held in treasury, reducing the total voting rights in the company to 613,344,565. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value by reducing the number of shares available in the market.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP presents a mixed outlook. The company’s financial stability, characterized by a robust balance sheet and improved cash flows, is a significant strength. However, the revenue volatility and negative valuation metrics pose challenges. The technical analysis reveals bearish trends, though the strategic share buyback program provides some positive momentum. Overall, the stock’s potential is offset by market and valuation concerns.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Capital Structure
Positive
Apr 25, 2025

Syncona Limited announced the purchase of 100,000 of its ordinary shares as part of its share buyback program. These shares will be held in treasury, reducing the total voting rights in the company to 613,434,565. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position as a leading life science investor.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s overall score reflects a strong financial foundation and positive corporate events, such as strategic buybacks and portfolio advancements. However, revenue volatility, technical bearishness, and valuation challenges remain significant concerns. While the company’s financial stability is a key strength, these challenges create a mixed outlook for the stock.

To see Spark’s full report on GB:SYNC stock, click here.

Private Placements and FinancingBusiness Operations and Strategy
Mosaic Therapeutics Advances with In-Licensing from Astex Pharmaceuticals
Positive
Apr 24, 2025

Mosaic Therapeutics, a portfolio company of Syncona Limited, has in-licensed two clinical-stage oncology assets from Astex Pharmaceuticals. This strategic move significantly de-risks and accelerates Mosaic’s development path, allowing the company to develop proprietary combination therapies targeting cancer patients with limited treatment options. The agreement includes Astex taking a 19% equity stake in Mosaic, with potential for an additional 3% based on clinical milestones. This partnership enhances Mosaic’s pipeline and positions it as a clinical-stage oncology business, with the first clinical combination study expected to commence in 2026.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP exhibits strong financial stability with a robust balance sheet and improving cash flows, offset by revenue volatility. The technical indicators suggest bearish trends, while the share buyback program provides some positive momentum. However, the negative valuation metrics present challenges, resulting in a mixed overall outlook.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Apr 24, 2025

Syncona Limited announced the purchase of 100,000 of its own ordinary shares as part of its ongoing share buyback programme. The shares were bought at a price of 88.4754 GBp each and will be held in treasury, reducing the total voting rights in the company to 613,534,565. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP exhibits strong financial stability with a robust balance sheet and improving cash flows, offset by revenue volatility. The technical indicators suggest bearish trends, while the share buyback program provides some positive momentum. However, the negative valuation metrics present challenges, resulting in a mixed overall outlook.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Apr 23, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback program. The shares were acquired at a price of 87.3658 GBp each and will be held in treasury, reducing the total voting rights to 613,634,565. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value by reducing the number of shares in circulation.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP has a strong financial base with zero debt and positive cash flow improvements, which is a significant positive factor. However, revenue volatility and a negative valuation metric are key challenges. The technical analysis indicates bearish trends, but the corporate strategy of share buybacks provides some support. Overall, the stock shows mixed signals, with financial resilience offset by market and valuation challenges.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Neutral
Apr 22, 2025

Syncona Limited announced the purchase of 100,000 of its ordinary shares as part of its ongoing share buyback program, with the shares to be held in treasury. This transaction affects the company’s total voting rights, now at 613,784,565, and is part of Syncona’s strategy to manage its capital structure effectively while focusing on long-term growth and shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s stock score is driven by its strong balance sheet and improved cash flow, which are key strengths. However, revenue volatility and negative valuation metrics pose significant challenges. The stock’s technical indicators are bearish, and while the share buyback program provides some positive momentum, it does not significantly alter the stock’s outlook.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Market Position
Positive
Apr 17, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme. The repurchased shares will be held in treasury, reducing the total voting rights to 613,884,565. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining a strong position in the life sciences investment sector.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s overall stock score reflects a balance of strong financial stability, supported by a robust balance sheet and improving cash flows, against challenges such as revenue volatility and negative valuation metrics. The stock exhibits bearish technical trends, but the strategic share buyback program provides some positive momentum. The lack of earnings call data limits insights into management’s forward guidance.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Capital Structure
Positive
Apr 16, 2025

Syncona Limited announced the repurchase of 83,827 of its ordinary shares as part of its ongoing share buyback program. The shares were bought at a price of 87.624 GBp each and will be held in treasury, reducing the total voting rights in the company to 614,034,565. This transaction aligns with Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its strong position in the life sciences investment sector.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s overall stock score reflects a balance of strong financial stability, supported by a robust balance sheet and improving cash flows, against challenges such as revenue volatility and negative valuation metrics. The stock exhibits bearish technical trends, but the strategic share buyback program provides some positive momentum. The lack of earnings call data limits insights into management’s forward guidance.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback as Part of Capital Strategy
Positive
Apr 15, 2025

Syncona Limited has executed a share buyback, purchasing 48,540 of its ordinary shares at a price of 85.0447 GBp per share as part of its ongoing Share Buyback Programme. These shares will be held in treasury, reducing the total voting rights to 614,118,392. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s overall score reflects a mix of financial strengths and challenges. The strong balance sheet and improved cash flows are offset by revenue volatility and negative valuation metrics. The technical analysis indicates bearish trends, while the strategic share buybacks provide some positive momentum but not enough to significantly alter the financial outlook.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback Programme
Neutral
Apr 14, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares at a price of 84.01 GBp per share as part of its ongoing share buyback programme. The repurchased shares will be held in treasury, affecting the total voting rights in the company, which now stands at 614,166,932. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s overall score reflects a mix of financial strengths and challenges. The strong balance sheet and improved cash flows are offset by revenue volatility and negative valuation metrics. The technical analysis indicates bearish trends, while the strategic share buybacks provide some positive momentum but not enough to significantly alter the financial outlook.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Apr 11, 2025

Syncona Limited has executed a share buyback transaction, purchasing 150,000 of its ordinary shares at a price of 84.7118 GBp per share as part of its ongoing Share Buyback Programme. These shares will be held in treasury, reducing the total voting rights in the company to 614,316,932. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP scores 64, exhibiting strong financial stability with a robust balance sheet and improving cash flows. However, revenue volatility and negative valuation metrics pose challenges. The stock is technically bearish, but the share buyback program provides some positive momentum.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Strengthen Capital Structure
Positive
Apr 10, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 of its ordinary shares at a price of 83.3005 GBp per share. These shares will be held in treasury, adjusting the company’s total voting rights to 614,466,932. This move aligns with Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and reflecting confidence in the company’s long-term growth prospects.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP scores a 61, reflecting a mixed outlook. The company’s financial stability is a significant strength, supported by a robust balance sheet and improving cash flows. However, revenue volatility and negative valuation metrics indicate underlying challenges. The technical indicators suggest bearish trends, but the strategic share buyback program provides some positive momentum.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Apr 9, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its share buyback programme. The shares were bought at a price of 84.6087 GBp each and will be held in treasury, reducing the total voting rights to 614,616,932. This transaction is part of Syncona’s strategy to manage its capital structure and enhance shareholder value.

Spark’s Take on GB:SYNC Stock

According to Spark, TipRanks’ AI Analyst, GB:SYNC is a Neutral.

Syncona Shs GBP’s overall stock score reflects a mixed picture. The company’s financial stability and cash flow improvements are significant strengths. However, technical indicators suggest bearish trends, and valuation metrics highlight potential overvaluation concerns. The extensive share buyback program is a positive corporate event, but it may not be enough to offset the challenges in financial performance and technical analysis.

To see Spark’s full report on GB:SYNC stock, click here.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Market Position
Positive
Apr 7, 2025

Syncona Limited has announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback program. The repurchased shares will be held in treasury, affecting the total voting rights within the company. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position as a leader in the life sciences investment sector.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Enhance Shareholder Value
Positive
Apr 4, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme. The shares were bought at a price of 87.9033 GBp each and will be held in treasury, reducing the total voting rights in the company to 615,066,932. This move is part of Syncona’s strategic financial management to optimize shareholder value and reflects its commitment to maintaining a robust balance sheet while focusing on long-term growth and sustainability in the life sciences sector.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Enhance Shareholder Value
Positive
Apr 3, 2025

Syncona Limited has executed a share buyback, purchasing 279,063 of its ordinary shares at a price of 86.7259 GBp per share as part of its ongoing Share Buyback Programme. The repurchased shares will be held in treasury, impacting the total voting rights available to shareholders, which now stand at 615,216,932. This move aligns with Syncona’s strategy to enhance shareholder value while maintaining a strong balance sheet to support its long-term investment goals in the life sciences sector.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Enhance Shareholder Value
Positive
Apr 2, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 of its ordinary shares at a price of 87.1868 GBp each. These shares will be held in treasury, reducing the total voting rights to 615,495,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and strengthening its market position.

Regulatory Filings and Compliance
Syncona Limited Updates Total Voting Rights for Shareholders
Neutral
Apr 1, 2025

Syncona Limited announced that as of March 31, 2025, the total number of voting rights in the company is 615,645,995, following the issuance of 672,214,632 ordinary shares, with 56,568,637 held in treasury. This update is crucial for shareholders to determine their interest in the company under the FCA’s Disclosure Guidance and Transparency Rules, impacting how they manage their investments.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Bolster Capital Structure
Positive
Apr 1, 2025

Syncona Limited announced the purchase of 350,000 of its ordinary shares as part of its ongoing share buyback programme. The shares were acquired at a price of 87.0885 GBp each and will be held in treasury, reducing the total voting rights in the company to 615,645,995. This transaction is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining a strong position in the life science investment industry.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback of 150,000 Shares
Neutral
Mar 31, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback program. The shares were bought at a price of 87.5365 GBp each and will be held in treasury, reducing the total voting rights in the company to 615,995,995. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Capital Structure
Positive
Mar 28, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 ordinary shares at a price of 87.9239 GBp per share. These shares will be held in treasury, reducing the total voting rights to 616,145,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and reflecting confidence in its long-term growth prospects.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Enhance Shareholder Value
Positive
Mar 27, 2025

Syncona Limited has executed a share buyback transaction as part of its ongoing Share Buyback Programme, purchasing 150,000 of its ordinary shares at a price of 87.675 GBp per share. These shares will be held in treasury, affecting the company’s total voting rights, which will now stand at 616,295,995. This strategic move is part of Syncona’s broader efforts to manage its capital structure and enhance shareholder value, reflecting its commitment to long-term growth and stability in the life sciences sector.

Stock Buyback
Syncona Limited Executes Share Buyback Programme
Neutral
Mar 26, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme, with shares bought at a volume-weighted average price of 87.3318 GBp. This transaction reduces the total voting rights in the company to 616,445,995, impacting shareholder calculations under the FCA’s Disclosure Guidance and Transparency Rules.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback Program
Positive
Mar 25, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 of its ordinary shares at a price of 88.9646 GBp per share. These shares will be held in treasury, reducing the total voting rights to 616,595,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its strong position in the life sciences investment sector.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Capital Structure
Positive
Mar 24, 2025

Syncona Limited has executed a share buyback program, purchasing 300,000 of its ordinary shares at a price of 90.1167 GBp per share. These shares will be held in treasury, reducing the total voting rights to 616,745,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining a strong balance sheet to support its long-term investment goals in the life sciences sector.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Optimize Capital Structure
Neutral
Mar 21, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 of its ordinary shares at a price of 94.314 GBp per share through Deutsche Numis. The repurchased shares will be held in treasury, reducing the total voting rights to 617,045,995. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Product-Related AnnouncementsBusiness Operations and StrategyFinancial Disclosures
Syncona’s Autolus Reports Strong 2024 Results and Strategic Advances
Positive
Mar 20, 2025

Autolus Therapeutics, a portfolio company of Syncona Ltd, has announced its 2024 financial results and business updates, highlighting the successful U.S. commercial launch of AUCATZYL® (obe-cel) for treating relapsed or refractory B-cell acute lymphoblastic leukemia. With 33 authorized treatment centers and plans for further expansion, Autolus is well-positioned to capture a significant market share. The company also anticipates regulatory approvals in the UK and EU by the second half of 2025. Additionally, Autolus is advancing its clinical pipeline, including trials for systemic lupus erythematosus, and plans to provide updates at an upcoming R&D event.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Enhance Shareholder Value
Positive
Mar 20, 2025

Syncona Limited has executed a share buyback transaction, purchasing 150,000 of its ordinary shares at a price of 94.30 GBp per share as part of its ongoing Share Buyback Programme. This transaction reduces the total voting rights in the company to 617,195,995, impacting shareholder calculations under the FCA’s Disclosure Guidance and Transparency Rules. The repurchased shares will be held in treasury, aligning with Syncona’s strategy to enhance shareholder value and maintain financial flexibility.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Enhance Capital Structure
Positive
Mar 19, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme. The shares were bought at a volume-weighted average price of 94.7088 GBp and will be held in treasury, reducing the total voting rights to 617,345,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position as a leading life science investor.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Strengthen Market Position
Positive
Mar 18, 2025

Syncona Limited has executed a share buyback program, purchasing 150,000 of its ordinary shares at a price of 93.1156 GBp each. These shares will be held in treasury, reducing the total voting rights in the company to 617,495,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position as a leader in the life sciences investment sector.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Mar 17, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback program, with shares acquired at a consistent price of 91.6715 GBp. This transaction will result in a total of 54,568,637 shares being held in treasury, affecting the total voting rights in the company, which will now stand at 617,645,995. This move is part of Syncona’s broader strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position in the life sciences investment sector.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Capital Structure
Positive
Mar 14, 2025

Syncona Limited announced a recent transaction under its share buyback programme, purchasing 150,000 of its ordinary shares at a consistent price of 91.2079 GBp per share. These shares will be held in treasury, affecting the company’s total voting rights, which now stand at 617,795,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and reflecting confidence in its long-term growth prospects.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Mar 13, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme. The repurchased shares will be held in treasury, adjusting the total voting rights in the company to 617,945,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position as a leading life science investor.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Market Position
Positive
Mar 12, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme. The shares were bought at a price of 90.7559 GBp each and will be held in treasury, reducing the total voting rights to 618,095,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its strong market position in the life sciences sector.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Mar 11, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback programme. The shares were acquired at a volume-weighted average price of 90.4733 GBp and will be held in treasury, reducing the total voting rights to 618,245,995. This move is part of Syncona’s strategy to manage its capital structure effectively and enhance shareholder value.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback, Adjusts Voting Rights
Neutral
Mar 10, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares at a price of 90.00 GBp each as part of its ongoing share buyback programme. This transaction reduces the total voting rights in the company to 618,545,995, impacting shareholder calculations under the FCA’s Disclosure Guidance and Transparency Rules. The repurchased shares will be held in treasury, aligning with Syncona’s strategy to manage its share capital effectively.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Market Position
Positive
Mar 6, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback program. The shares were bought at a consistent price of 93.6764 GBp each and will be held in treasury, reducing the total voting rights to 619,045,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its market position.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Neutral
Mar 5, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback program. The shares were acquired at a price of 95.7971 GBp each and will be held in treasury, impacting the company’s total voting rights and share capital structure. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

M&A TransactionsBusiness Operations and Strategy
The Wellcome Trust Acquires Major Stake in Syncona Limited
Neutral
Mar 4, 2025

Syncona Limited, a UK-based company, has announced a significant change in its voting rights structure. The Wellcome Trust Limited, acting as a trustee, has acquired a substantial 30.0026% of the voting rights in Syncona Limited, marking a notable shift in shareholder influence. This acquisition, which was finalized on February 27, 2025, and announced on February 28, 2025, underscores a strategic move by The Wellcome Trust to potentially influence Syncona’s future decisions and direction.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Mar 4, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its share buyback program, with the shares to be held in treasury. This transaction reduces the total voting rights in the company to 619,345,995, impacting shareholder calculations under FCA guidelines. The buyback reflects Syncona’s strategic focus on enhancing shareholder value and optimizing its capital structure, reinforcing its commitment to delivering strong risk-adjusted returns.

Regulatory Filings and Compliance
Syncona Limited Announces Total Voting Rights Update
Neutral
Mar 3, 2025

Syncona Limited announced that as of 28 February 2025, the total number of ordinary shares in issue is 672,214,632, with 52,718,637 shares held in treasury, resulting in 619,495,995 voting rights. This figure is crucial for shareholders to determine their notification obligations under the FCA’s Disclosure Guidance and Transparency Rules. This announcement provides transparency and clarity on the company’s share structure, which is important for stakeholders to understand their voting rights and obligations, potentially impacting shareholder decisions and company governance.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Neutral
Mar 3, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback program. The repurchased shares will be held in treasury, reducing the total voting rights in the company to 619,495,995. This move is part of Syncona’s strategy to manage its capital structure effectively, which may have implications for shareholder value and market perception.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Feb 27, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback programme. The repurchased shares will be held in treasury, affecting the total voting rights available to shareholders. This move is part of Syncona’s strategy to manage its capital structure and potentially enhance shareholder value.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Enhance Shareholder Value
Positive
Feb 25, 2025

Syncona Limited has executed a share buyback, purchasing 150,000 of its ordinary shares at a consistent price of 95.7333 GBp per share, as part of its ongoing Share Buyback Programme. These shares will be held in treasury, impacting the total voting rights in the company, which now stands at 620,095,995. This move is part of Syncona’s strategy to manage its capital structure effectively, potentially enhancing shareholder value and maintaining its position as a leading life science investor.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback of 150,000 Ordinary Shares
Neutral
Feb 24, 2025

Syncona Limited announced the purchase of 150,000 ordinary shares as part of its ongoing share buyback programme, executed through Deutsche Numis. This transaction reduces the company’s total voting shares to 620,245,995, affecting shareholder calculations under the FCA’s rules. The repurchased shares will be held in treasury, aligning with Syncona’s strategic approach to maintain a flexible balance sheet for long-term investment and growth.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Acquires 150,000 Shares Under Buyback Program
Positive
Feb 21, 2025

Syncona Limited has announced the purchase of 150,000 of its ordinary shares as part of its ongoing share buyback program, initially announced in September 2023. The purchased shares will be held in treasury, which impacts the company’s total voting rights, now totaling 620,395,995. This strategic move is in line with Syncona’s commitment to enhance shareholder value while maintaining a robust balance sheet to support its life sciences investment initiatives.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Optimize Capital Structure
Positive
Feb 20, 2025

Syncona Limited has announced the purchase of 150,000 of its own ordinary shares as part of a previously announced share buyback program. The shares were acquired at a volume-weighted average price of 94.3309 GBp and will be held in treasury, affecting the total voting rights for shareholders. This transaction reflects Syncona’s strategic efforts to manage its capital structure and potentially enhance shareholder value.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Enhance Shareholder Value
Positive
Feb 19, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its share buyback programme. These shares will be held in treasury, affecting the total voting rights available. This acquisition reflects Syncona’s strategic financial management and commitment to enhancing shareholder value, highlighting its strong market positioning within the life sciences investment industry.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Advances Share Buyback with New Purchase
Positive
Feb 18, 2025

Syncona Limited announced the purchase of 150,000 ordinary shares at a price of 91.70 GBp each as part of its ongoing share buyback programme. This transaction aligns with the company’s strategy to manage its share capital effectively, enhancing shareholder value. The repurchased shares will be held in treasury, impacting the total voting rights within the company and potentially influencing shareholder calculations regarding their stakes.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback of 150,000 Shares
Neutral
Feb 17, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its ongoing share buyback program, with all shares priced at 90.50 GBp. This transaction increases the total number of shares held in treasury to 51,218,637, reducing the total voting shares to 620,995,995. The buyback reflects the company’s strategy to manage its share capital effectively and may influence shareholder interest calculations under FCA rules.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Enhance Strategic Financial Management
Positive
Feb 14, 2025

Syncona Limited has executed a share buyback, purchasing 150,000 of its ordinary shares at a price of 90.6421 GBp each, as part of its ongoing Share Buyback Programme. These repurchased shares will be held in treasury, impacting the total voting rights in the company, which now stands at 621,145,995. This move reflects the company’s strategic financial management and could potentially influence shareholder value and market perception.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Announces Share Buyback
Positive
Feb 13, 2025

Syncona Limited announced the purchase of 150,000 of its ordinary shares as part of its share buyback programme. The repurchased shares will be held in treasury, impacting the company’s total voting rights. This move reflects Syncona’s strategic approach to managing its capital structure and possibly enhancing shareholder value.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Strategic Share Buyback Programme
Positive
Feb 12, 2025

Syncona Limited has executed a share buyback, purchasing 150,000 of its ordinary shares at a consistent price of 91.22 GBp each, as part of its previously announced Share Buyback Programme. These shares will be held in treasury, reducing the total voting rights to 621,445,995. This buyback reflects Syncona’s strategic approach to managing its capital structure and could potentially enhance shareholder value.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Share Buyback to Optimize Capital Structure
Neutral
Feb 11, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its share buyback programme. The shares were bought at a consistent price of 92.3333 GBp per share and will be held in treasury, affecting the total voting rights available to shareholders. This transaction reflects Syncona’s ongoing strategy to manage its capital structure effectively and deliver value to its stakeholders.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Enhances Capital Structure with Share Buyback
Neutral
Feb 10, 2025

Syncona Limited announced a recent transaction involving the purchase of 175,000 of its ordinary shares as part of its ongoing share buyback program. These shares will be held in treasury, adjusting the total voting rights within the company. This move aligns with Syncona’s strategy to manage its capital structure while continuing to focus on delivering impactful treatments and sustainable growth in the life sciences industry.

Stock BuybackBusiness Operations and Strategy
Syncona Limited Executes Share Buyback to Strengthen Capital Structure
Neutral
Feb 7, 2025

Syncona Limited has announced a transaction involving the repurchase of 175,000 of its ordinary shares at a volume weighted average price of 92.3143 pence per share as part of its ongoing share buyback programme. These shares will be held in treasury, impacting the company’s total voting rights, which now stands at 621,920,995. This move is aligned with Syncona’s strategy to manage its capital structure and maintain its focus on building a strong portfolio within the life sciences sector, potentially enhancing shareholder value.

Stock BuybackBusiness Operations and StrategyFinancial Disclosures
Syncona Limited Reports Third Quarter Performance and Portfolio Progress
Neutral
Feb 6, 2025

Syncona Limited reported a slight decline in net assets in its third-quarter update, citing volatility in the share price of Autolus as a contributing factor. Despite this, the company has seen progress in its portfolio with three key value inflection points achieved, including promising clinical data from Beacon and Spur. The company continues to prioritize disciplined capital allocation, with additional funds directed towards share buybacks following the partial realization of Autolus holdings. Syncona’s leadership is confident in the portfolio’s ability to deliver strong risk-adjusted returns over time, despite broader market challenges.

Stock BuybackRegulatory Filings and Compliance
Syncona Limited Executes Share Buyback, Impacting Voting Rights
Neutral
Feb 5, 2025

Syncona Limited announced the purchase of 51,844 of its ordinary shares as part of its ongoing share buyback programme, with shares bought at a volume weighted average price of 91.0357 GBp each. The repurchased shares will be held in treasury, reducing the total voting rights to 622,095,995, which may impact shareholder voting calculations under the FCA’s Disclosure Guidance and Transparency Rules.

Legal ProceedingsBusiness Operations and Strategy
Achilles Therapeutics to Undergo Voluntary Liquidation, Impacting Syncona’s Portfolio
Negative
Feb 5, 2025

Achilles Therapeutics plc, an investment of Syncona Limited, announced plans for a members’ solvent voluntary liquidation to return capital to shareholders. The estimated return to ordinary shareholders is between £1.20 to £1.32 per share. Syncona holds 11,086,909 shares in Achilles, with its holding valued at £8.5 million as of September 2024. This move is expected to affect Syncona’s portfolio value and may influence stakeholders’ perceptions of its investment strategy.

Product-Related AnnouncementsBusiness Operations and Strategy
Syncona’s Spur Therapeutics Reports Promising Gene Therapy Data in Gaucher Disease Trial
Positive
Feb 4, 2025

Syncona Ltd’s portfolio company, Spur Therapeutics, announced positive results from its Phase I/II GALILEO-1 study of FLT201, a gene therapy candidate for Gaucher disease. The trial demonstrated significant improvements in patients’ conditions, including reductions in glucosylsphingosine levels and sustained improvements in blood counts and organ volumes, while maintaining a favorable safety profile. These promising results, presented at the WORLDSymposium, highlight FLT201’s potential to become a first-class gene therapy for Gaucher disease, paving the way for accelerated approval and a pivotal Phase III trial in 2027, marking a significant milestone for Syncona.

Stock BuybackBusiness Operations and Strategy
Syncona Executes Strategic Share Buyback
Positive
Feb 4, 2025

Syncona Limited announced the purchase of 150,000 of its own ordinary shares as part of its share buyback program, executed through Deutsche Numis. The repurchased shares will be held in treasury, reducing the total voting rights in the company to 622,147,839. This action is part of Syncona’s strategy to manage its capital structure effectively and enhance shareholder value.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.