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Syncona Shs GBP (GB:SYNC)
LSE:SYNC
UK Market
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Syncona Shs GBP (SYNC) AI Stock Analysis

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GB:SYNC

Syncona Shs GBP

(LSE:SYNC)

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Neutral 60 (OpenAI - 5.2)
Rating:60Neutral
Price Target:
112.00 p
▲(19.28% Upside)
Action:Reiterated
Date:06/19/26
The score is anchored by balance-sheet strength (debt-free, large equity base), but is held back by inconsistent profitability and a recent drop of free cash flow to zero. Technicals are supportive with the price above major moving averages and positive MACD, while valuation remains constrained by losses implied by the negative P/E.
Positive Factors
Zero debt balance sheet
A zero-debt balance sheet materially lowers financial risk and enhances resilience over multi-year development cycles. It gives Syncona durable funding flexibility to support portfolio companies through clinical milestones without near-term refinancing pressure, preserving optionality.
Negative Factors
Volatile profitability and revenue decline
Shifting from profit to consecutive loss years and recent revenue decline reduce visibility into NAV growth and long-term return generation. Persistent profitability volatility undermines predictability of distributable value and complicates multi-period planning for exits and reinvestment.
Read all positive and negative factors
Positive Factors
Negative Factors
Zero debt balance sheet
A zero-debt balance sheet materially lowers financial risk and enhances resilience over multi-year development cycles. It gives Syncona durable funding flexibility to support portfolio companies through clinical milestones without near-term refinancing pressure, preserving optionality.
Read all positive factors

Syncona Shs GBP (SYNC) vs. iShares MSCI United Kingdom ETF (EWC)

Syncona Shs GBP Business Overview & Revenue Model

Company Description
Syncona Ltd. is a closed-end investment fund, which engages in delivering returns from investments in long and alternative investment funds across multiple asset classes and targets. Its portfolio includes commercial companies, late-stage clinical...
How the Company Makes Money
Syncona makes money primarily through investment returns from its life-sciences portfolio rather than through selling products or services itself. Its key economic driver is the change in value of its holdings (net asset value), which can increase...

Syncona Shs GBP Financial Statement Overview

Summary
Strong balance-sheet safety with zero debt and substantial equity supports resilience, but profitability and revenue have been volatile with losses in FY2025–FY2026 and declining FY2026 revenue. Cash flow is mixed: operating cash flow is positive recently, yet free cash flow fell to zero in FY2026, weakening overall quality.
Income Statement
34
Negative
Balance Sheet
78
Positive
Cash Flow
53
Neutral
BreakdownMar 2025Mar 2024Mar 2023Mar 2022Mar 2021
Income Statement
Total Revenue57.34M-68.31M30.75M-39.79M18.69M
Gross Profit43.36M-68.31M14.10M-51.91M3.68M
EBITDA-8.80M-143.16M8.14M0.0011.15M
Net Income-8.80M-143.16M3.79M-56.02M8.84M
Balance Sheet
Total Assets1.05B1.06B1.25B1.27B1.33B
Cash, Cash Equivalents and Short-Term Investments1.92M1.11M261.00K11.00K276.00K
Total Debt0.000.000.000.000.00
Total Liabilities14.95M11.79M12.22M13.76M23.55M
Stockholders Equity1.04B1.05B1.24B1.25B1.31B
Cash Flow
Free Cash Flow0.0043.91M20.47M-265.00K262.00K
Operating Cash Flow23.33M43.91M20.47M-265.00K262.00K
Investing Cash Flow-15.75M0.000.000.000.00
Financing Cash Flow-6.78M-43.06M-20.22M0.000.00

Syncona Shs GBP Technical Analysis

Technical Analysis Sentiment
Positive
Last Price93.90
Price Trends
50DMA
100.36
Positive
100DMA
95.97
Positive
200DMA
97.04
Positive
Market Momentum
MACD
2.29
Positive
RSI
61.25
Neutral
STOCH
25.59
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:SYNC, the sentiment is Positive. The current price of 93.9 is below the 20-day moving average (MA) of 104.92, below the 50-day MA of 100.36, and below the 200-day MA of 97.04, indicating a bullish trend. The MACD of 2.29 indicates Positive momentum. The RSI at 61.25 is Neutral, neither overbought nor oversold. The STOCH value of 25.59 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:SYNC.

Syncona Shs GBP Peers Comparison

Overall Rating
UnderperformOutperform
Sector (68)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
£1.94B14.874.51%2.40%68.95%109.67%
72
Outperform
£1.39B11.9014.60%9.91%-21.74%58.92%
68
Neutral
$18.00B11.429.92%3.81%9.73%1.22%
65
Neutral
£1.02B8.668.51%-78.12%30945.45%
61
Neutral
£570.69M8.657.16%-35.12%
60
Neutral
£650.77M-74.31-9.02%-40.88%93.65%
52
Neutral
£113.91M-13.301.79%3.29%-2.25%-353.75%
* Financial Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:SYNC
Syncona Shs GBP
107.00
11.40
11.92%
GB:ASHM
Ashmore Group PLC
210.00
47.78
29.45%
GB:GROW
Molten Ventures
589.00
232.40
65.17%
GB:IPO
IP Group plc
64.60
6.00
10.24%
GB:MERC
Mercia Asset Management
27.00
-5.00
-15.63%
GB:CLDN
Caledonia Investments
380.50
27.76
7.87%

Syncona Shs GBP Corporate Events

Financial DisclosuresRegulatory Filings and ComplianceShareholder Meetings
Syncona Publishes 2026 Annual Report and Sets August AGM
Neutral
Jul 3, 2026
Syncona Ltd, the U.K.-listed life sciences investor, has released its Annual Report and Accounts for the year to 31 March 2026 alongside the formal notice of its 2026 Annual General Meeting. The documents have been filed with the Financial Conduct...
Other
Syncona Director Increases Stake with Share Purchase on London Stock Exchange
Positive
Jun 22, 2026
Syncona Limited reported that non-executive director John Patrick Roche purchased 16,063 ordinary shares of the company on 19 June 2026 at a price of £0.996 per share on the London Stock Exchange. The transaction, conducted in British pounds,...
Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresShareholder Meetings
Syncona Sets £250m Return Target as Portfolio Advances to Late-Stage Trials
Positive
Jun 18, 2026
Syncona reported largely stable full-year results, with net assets of £1.04 billion and modest gains in its life sciences portfolio driven by a valuation uplift at Beacon Therapeutics following an oversubscribed Series C financing. The group ...
Business Operations and StrategyExecutive/Board Changes
Syncona appoints veteran investment specialist Norman Crighton to board
Positive
Jun 17, 2026
Syncona Ltd has appointed veteran investment company specialist Norman Crighton as an independent non-executive director from 1 July 2026, adding more than three decades of experience in investment banking, fund management and board governance to ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 19, 2026