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Nuformix Plc (GB:NFX)
LSE:NFX

Nuformix Plc (NFX) AI Stock Analysis

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GB:NFX

Nuformix Plc

(LSE:NFX)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
0.19p
▼(-19.13% Downside)
The score is primarily weighed down by weak financial performance (no revenue, persistent losses, and ongoing cash burn), which dominates the assessment. Technicals are also soft with the stock trading below key shorter-term averages and negative MACD, only partially offset by near-oversold readings. Valuation signals are limited because the company is loss-making (negative P/E) and no dividend yield is available.
Positive Factors
Very low leverage / no debt
A debt-free balance sheet materially reduces solvency risk and preserves strategic flexibility. Over the next several months this allows management to pursue licensing or partnership discussions without near-term interest obligations, supporting financing optionality and downside protection.
Lean operating footprint
A very small headcount keeps fixed overhead and burn low, helping stretch available cash and enabling the company to allocate limited resources to core R&D and partner outreach. This structural nimbleness supports survival while seeking non-dilutive partnerships or financing.
Focused repurposing strategy
A strategy centered on reformulating approved drugs can shorten development timelines and reduce clinical risk versus new chemical entities. That focus increases the likelihood of partnering/licensing for later-stage development and commercialization, a durable pathway to value.
Negative Factors
Zero recent revenue
The absence of meaningful revenue indicates the company has not commercialized products and lacks operating cash inflows. Structurally, this prevents internal funding of R&D and operations, forcing reliance on external capital and complicating sustainable growth planning over coming months.
Consistent negative cash flow
Persistent negative operating and free cash flow shows cash burn is structural rather than episodic. With cash outflows worsening in 2025 after a temporary improvement, the company will likely need recurring financings, which can dilute shareholders and constrain long-term R&D pacing.
Eroded equity and small asset base
Material shrinkage of equity and assets reduces the firm’s financial resilience. A small balance sheet offers limited buffer against development setbacks, weakens negotiating leverage with partners, and increases the urgency of external funding, raising long-term execution risk.

Nuformix Plc (NFX) vs. iShares MSCI United Kingdom ETF (EWC)

Nuformix Plc Business Overview & Revenue Model

Company DescriptionNuformix plc operates in the field of pharmaceutical development for treating fibrosis and oncology through drug repurposing in the United Kingdom. It offers NXP001, which has completed Phase 1 for use in oncology supportive care. The company is also developing NXP004, a novel form of Olaparib, which is in the IP generation phase for treating oncology; and NXP002 that is in pre-clinical stage for the treatment of idiopathic pulmonary fibrosis. It also has an option agreement with Oxilio Ltd. for NXP001 for oncology indications. Nuformix plc was founded in 2008 and is based in London, the United Kingdom.
How the Company Makes MoneyNuformix Plc generates revenue through the development and licensing of its proprietary cocrystal technology to pharmaceutical partners. The company partners with other pharmaceutical organizations to co-develop drugs, sharing in the costs and revenues associated with these products. Additional revenue streams include milestone payments and royalties from successful commercialization of the drugs using their technology. Significant partnerships with larger pharmaceutical firms help in leveraging Nuformix's technology, providing a pathway to market for their innovations and contributing to its earnings.

Nuformix Plc Financial Statement Overview

Summary
Income statement and cash flow are weak due to zero recent revenue, ongoing net losses, and consistently negative free cash flow (continued cash burn). The main offset is a low-risk capital structure with no debt, but the shrinking equity and asset base reduces financial resilience.
Income Statement
18
Very Negative
The company has not generated meaningful revenue in recent years (revenue is £0 in 2023–2025 annual reports, versus £535k in 2020), indicating a weak or stalled commercialization profile. Profitability is consistently negative, with ongoing operating losses and net losses each year (e.g., net loss of ~£0.65m in 2025 and ~£3.64m in 2024). While the 2025 loss is much smaller than 2024 (suggesting cost tightening or one-off effects), the business remains structurally loss-making and lacks a clear revenue rebound in the provided data.
Balance Sheet
52
Neutral
Leverage is very low (total debt is £0 in 2021–2025, and modest in 2020), which reduces financial risk and provides flexibility. However, the equity base has declined materially from 2021–2023 levels to ~£0.75m in 2025, reflecting cumulative losses and/or balance sheet actions, and total assets have similarly stepped down to ~£1.02m in 2025. Overall, the balance sheet is not debt-burdened, but it appears significantly smaller and potentially more fragile than in prior years.
Cash Flow
24
Negative
Cash generation is weak, with operating cash flow and free cash flow negative every year shown (e.g., free cash flow of about -£0.61m in 2025 and -£0.33m in 2024). Cash burn fluctuates, improving in 2024 versus 2023 but worsening again in 2025, indicating limited consistency in cash discipline. With losses and ongoing cash outflows, the company likely remains dependent on external funding to sustain operations.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.0050.00K195.55K
Gross Profit-28.63K-28.63K0.00-36.75K11.33K86.72K
EBITDA-270.22K-631.94K-477.19K-581.90K-1.23M-1.28M
Net Income-652.59K-652.59K-3.64M-572.98K-1.11M-1.25M
Balance Sheet
Total Assets1.02M1.02M970.54K4.42M4.98M6.01M
Cash, Cash Equivalents and Short-Term Investments97.55K97.55K20.21K202.55K464.10K1.67M
Total Debt0.000.000.000.000.000.00
Total Liabilities263.92K263.92K254.97K222.99K237.86K324.62K
Stockholders Equity754.93K754.93K715.57K4.20M4.74M5.69M
Cash Flow
Free Cash Flow-223.95K-614.61K-331.88K-397.49K-1.35M-848.83K
Operating Cash Flow-223.95K-614.61K-331.88K-397.49K-1.35M-848.22K
Investing Cash Flow0.000.000.0033.33K0.0043.72K
Financing Cash Flow691.95K691.95K149.54K189.79K139.98K1.93M

Nuformix Plc Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.23
Price Trends
50DMA
0.27
Negative
100DMA
0.26
Negative
200DMA
0.18
Positive
Market Momentum
MACD
-0.02
Positive
RSI
28.92
Positive
STOCH
9.04
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:NFX, the sentiment is Negative. The current price of 0.23 is below the 20-day moving average (MA) of 0.28, below the 50-day MA of 0.27, and above the 200-day MA of 0.18, indicating a neutral trend. The MACD of -0.02 indicates Positive momentum. The RSI at 28.92 is Positive, neither overbought nor oversold. The STOCH value of 9.04 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:NFX.

Nuformix Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
£7.67M-0.64-115.97%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
£44.46M-3.32-609.30%
46
Neutral
£4.01M-4.75-153.80%-616.67%
46
Neutral
£31.97M-7.15-259.88%
45
Neutral
£4.51M-1.62-53.79%85.56%
43
Neutral
£7.49M-51.79-2.42%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:NFX
Nuformix Plc
0.19
0.12
167.61%
GB:TCF
Evgen Pharma
0.21
-1.01
-82.79%
GB:FUM
Futura Medical
1.32
-15.14
-91.98%
GB:IMM
ImmuPharma
6.36
1.26
24.71%
GB:OPTI
OptiBiotix Health
7.25
-8.63
-54.35%
GB:HEMO
HemoGenyx Pharmaceuticals Plc
736.00
398.00
117.75%

Nuformix Plc Corporate Events

Business Operations and StrategyFinancial Disclosures
Nuformix Sharpens Focus on Partnering Lead IPF Drug NXP002 as Preclinical Data Strengthen Case
Positive
Jan 27, 2026

In its annual results for the year to 30 September 2025, Nuformix highlighted its strategic focus on securing a business development partner for NXP002, its lead preclinical asset – a patent-protected, inhaled form of tranilast being developed as a novel treatment for idiopathic pulmonary fibrosis (IPF), progressive pulmonary fibrosis (PPF) and other fibrosing interstitial lung diseases. The company reported a series of encouraging preclinical data sets showing that NXP002 can be effectively delivered to the deep lung via nebulisation, is well tolerated at high doses in vivo and ex vivo, and delivers strong anti-fibrotic and anti-inflammatory effects both as a monotherapy and in combination with current standards of care, with additive benefits that suggest action on additional disease pathways. Further studies indicated that NXP002 achieves a durable anti-inflammatory effect consistent with a twice-daily dosing profile and demonstrates a clear dose response across key fibrotic biomarkers in human lung tissue models, strengthening its positioning as a potentially differentiated inhaled therapy in a rapidly growing IPF/PPF market and supporting Nuformix’s ongoing discussions with potential licensing and development partners.

Business Operations and StrategyRegulatory Filings and Compliance
Nuformix PLC Updates Total Voting Rights Following New Share Issuance
Neutral
Nov 28, 2025

Nuformix PLC has announced the issuance of new ordinary shares, confirming its total voting rights as 2,109,749,903 shares, each carrying one voting right. This update aligns with the FCA’s Disclosure Guidance and Transparency Rules, providing shareholders with the necessary information to assess their interests in the company. This development is part of the company’s strategic financial management and may influence stakeholder decisions regarding shareholding notifications.

Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Nuformix Awaits FDA Response on Orphan Drug Designation for IPF Treatment
Neutral
Nov 12, 2025

Nuformix plc has announced that the US FDA has requested further clarification on a specific element of its Orphan Drug Designation application for tranilast, part of its NXP002 programme targeting Idiopathic Pulmonary Fibrosis (IPF). The company plans to respond promptly using existing data, and remains optimistic about a successful outcome. Meanwhile, Nuformix is in discussions with potential licensing partners, indicating ongoing strategic efforts to advance its market position.

Private Placements and Financing
Nuformix plc Successfully Completes Oversubscribed Open Offer
Positive
Nov 12, 2025

Nuformix plc announced the results of its underwritten Open Offer, which closed on November 11, 2025. The offer was oversubscribed with valid acceptances for 465,813,047 shares, representing a take-up of approximately 408.5% of the available shares. The company will issue 114,040,535 shares, raising approximately £228,081 before expenses. This successful capital raise is expected to enhance Nuformix’s financial position and support its ongoing development efforts in the pharmaceutical sector.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 28, 2026