Successful Enrollment of Phase III Trials
Completed enrollment of the LUCIA trial, the second Phase III trial for DURAVYU in wet AMD, in just 7 months. Over 900 patients were recruited, making it one of the fastest enrolling wet AMD pivotal programs.
Strong Financial Position
Ended September 2025 with over $200 million in cash and equivalents, and closed a $172 million follow-on offering in October. Cash is expected to fund operations into Q4 2027.
Phase III DME Program Advancements
Aligned with the FDA on a non-inferiority trial design for the DME program. First patient dosing is expected in Q1 2026.
Multi-Mechanism of Action for DURAVYU
New preclinical data shows vorolanib, the active drug in DURAVYU, inhibits both VEGF-mediated vascular permeability and IL-6 mediated inflammation, supporting its potential effectiveness in multifactorial diseases like wet AMD and DME.