Record Revenue Growth
Total revenue for Q3 2025 grew 69% year-over-year to $87.3 million, with U.S. net product revenue increasing 31% year-over-year to $40.7 million.
Commercial Strategy Success
Esperion achieved nearly double-digit sequential quarterly prescription growth. Their strategic marketing initiatives, such as the 'Can’t take a statin? Make NEXLIZET happen!' campaign, have significantly increased brand awareness and prescriber engagement.
Strategic Partnerships and Approvals
Esperion finalized agreements with 4 generic manufacturers, ensuring no market entry of generic versions of NEXLETOL and NEXLIZET before April 2040. Additionally, bempedoic acid was included in the ESC/EAS guidelines, with U.S. guidelines expected to follow in early 2026.
International Expansion
Partnerships with Daiichi Sankyo Europe and Otsuka Pharmaceutical have shown strong growth, with significant market shares in Europe and upcoming launch in Japan. Royalty revenue from DSE increased 21% sequentially to $16.4 million.
Pipeline Advancements
Nomination of ESP-2001 as a preclinical development candidate for primary sclerosing cholangitis, with plans to initiate first-in-human clinical studies in 2026.