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Enanta Pharmaceuticals (ENTA)
NASDAQ:ENTA

Enanta Pharmaceuticals (ENTA) AI Stock Analysis

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ENTA

Enanta Pharmaceuticals

(NASDAQ:ENTA)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$14.50
▼(-0.89% Downside)
Action:ReiteratedDate:03/13/26
The score is primarily constrained by weak financial performance—large ongoing losses and continued cash burn—despite improved revenue momentum and a healthier leverage profile. Technicals are moderately supportive with price holding above key moving averages and neutral momentum. Valuation is limited by negative earnings, while the corporate event is modestly positive for governance but includes potential dilution from additional incentive-plan shares.
Positive Factors
Revenue rebound and high gross margin
Sustained top-line recovery combined with a ~72% gross margin indicates the business benefits from high-margin licensing/royalty economics and/or scalable product revenue. That margin profile supports durable reinvestment in R&D and protects operating leverage as revenue scales.
Negative Factors
Negative operating and free cash flow
Persistent operating and free cash outflows elevate funding risk and likely require future external capital (equity or debt). That need can force dilutive financings or expensive borrowing, constrain the pace of internal R&D, and increase strategic dependence on partner milestone receipts.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue rebound and high gross margin
Sustained top-line recovery combined with a ~72% gross margin indicates the business benefits from high-margin licensing/royalty economics and/or scalable product revenue. That margin profile supports durable reinvestment in R&D and protects operating leverage as revenue scales.
Read all positive factors

Enanta Pharmaceuticals (ENTA) vs. SPDR S&P 500 ETF (SPY)

Enanta Pharmaceuticals Business Overview & Revenue Model

Company Description
Enanta Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs for the treatment of viral infections and liver diseases. Its research and development disease targets include respiratory syncytial virus, SARS-CoV...
How the Company Makes Money
Enanta primarily makes money through (1) collaboration and licensing revenue and (2) potential future product revenue if it commercializes any of its wholly owned drug candidates. Collaboration/licensing revenue is generated by granting partners r...

Enanta Pharmaceuticals Earnings Call Summary

Earnings Call Date:May 06, 2024
(Q2-2024)
|
% Change Since: |
Next Earnings Date:May 11, 2026
Earnings Call Sentiment Neutral
The earnings call presented a mixed sentiment with significant advancements in the RSV and immunology programs and a stable financial position. However, it also highlighted challenges with a decline in revenue, increased net loss, and slower enrollment in the RSVPEDs study.
Positive Updates
RSV Program Advancements
Progress in developing the first oral antiviral treatment for RSV, with two Phase II studies (RSVPEDs and RSVHR) ongoing and anticipation of reporting data in the second half of 2024.
Negative Updates
Revenue Decline
Total revenue for the quarter decreased to $17.1 million from $17.8 million in the same period in 2023, primarily due to lower royalty rates.
Read all updates
Q2-2024 Updates
Negative
RSV Program Advancements
Progress in developing the first oral antiviral treatment for RSV, with two Phase II studies (RSVPEDs and RSVHR) ongoing and anticipation of reporting data in the second half of 2024.
Read all positive updates
Company Guidance
During the earnings call for Enanta Pharmaceuticals' fiscal second quarter of 2024, the company provided guidance on several key metrics. For the quarter, total revenue was reported at $17.1 million, primarily from royalty revenue tied to AbbVie's MAVYRET sales. The company updated its expense guidance, projecting research and development expenses to range between $125 million and $145 million, reflecting increased investment in its RSV and new immunology programs. General and administrative expenses are expected to be between $50 million and $60 million, influenced by additional stock compensation and legal costs. Enanta concluded the quarter with approximately $300 million in cash and marketable securities, anticipating this will support its existing operations through the third quarter of fiscal 2027. The company is also advancing its RSV and CSU programs, with milestones including data readouts expected in the second half of 2024 and the introduction of a second immunology program.

Enanta Pharmaceuticals Financial Statement Overview

Summary
Revenue rebounded sharply and gross margin is healthy (~72%), and leverage has improved to a more moderate level. However, results remain dominated by large operating losses and materially negative margins, with continued negative operating cash flow/free cash flow, keeping overall financial quality weak despite balance-sheet progress.
Income Statement
22
Negative
Balance Sheet
58
Neutral
Cash Flow
33
Negative
BreakdownTTMSep 2025Sep 2024Sep 2023Sep 2022Sep 2021
Income Statement
Total Revenue66.98M65.32M67.64M79.20M86.16M97.07M
Gross Profit66.98M60.74M67.64M79.20M86.16M97.07M
EBITDA-59.03M-70.78M-104.51M-123.48M-119.22M-104.25M
Net Income-71.54M-81.89M-116.05M-133.82M-121.75M-79.00M
Balance Sheet
Total Assets329.50M280.73M376.65M462.27M380.59M440.86M
Cash, Cash Equivalents and Short-Term Investments185.85M188.86M248.19M369.91M249.23M244.00M
Total Debt193.18M201.06M226.06M222.44M26.69M6.83M
Total Liabilities202.91M216.01M247.84M245.54M59.26M41.43M
Stockholders Equity126.59M64.72M128.81M216.74M321.33M399.43M
Cash Flow
Free Cash Flow-18.46M-32.17M-96.71M-112.21M-86.91M-70.75M
Operating Cash Flow-14.17M-19.27M-78.76M-103.15M-84.78M-70.00M
Investing Cash Flow-75.85M40.35M58.23M-53.58M54.90M36.99M
Financing Cash Flow42.50M-26.62M-27.63M198.13M20.03M3.08M

Enanta Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price14.63
Price Trends
50DMA
13.56
Positive
100DMA
13.76
Positive
200DMA
11.40
Positive
Market Momentum
MACD
0.22
Negative
RSI
65.90
Neutral
STOCH
91.11
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ENTA, the sentiment is Positive. The current price of 14.63 is above the 20-day moving average (MA) of 13.07, above the 50-day MA of 13.56, and above the 200-day MA of 11.40, indicating a bullish trend. The MACD of 0.22 indicates Negative momentum. The RSI at 65.90 is Neutral, neither overbought nor oversold. The STOCH value of 91.11 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ENTA.

Enanta Pharmaceuticals Risk Analysis

Enanta Pharmaceuticals disclosed 50 risk factors in its most recent earnings report. Enanta Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Enanta Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$911.86M-3.80-50.23%14.68%89.16%
54
Neutral
$562.55M-5.15-26.87%60.40%
52
Neutral
$414.11M-7.06-78.59%-3.42%30.03%
52
Neutral
$745.96M-1.58-57.07%-100.00%37.10%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$288.67M3.9253.18%
44
Neutral
$375.00M-1.23-113.81%20.71%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ENTA
Enanta Pharmaceuticals
14.63
9.70
196.75%
ABEO
Abeona Therapeutics
5.19
0.34
7.01%
TECX
Tectonic Therapeutic
29.95
12.39
70.56%
ALLO
Allogene Therapeutics
2.28
0.88
62.86%
JBIO
Jade Biosciences
19.44
9.64
98.37%
NMRA
Neumora Therapeutics, Inc.
2.03
1.40
222.22%

Enanta Pharmaceuticals Corporate Events

Business Operations and StrategyLegal Proceedings
Enanta Advances Federal Circuit Appeal in Paxlovid Patent Case
Neutral
Mar 26, 2026
Enanta Pharmaceuticals, Inc., a biotechnology company specializing in small-molecule antiviral therapies, is pursuing litigation to protect its intellectual property related to COVID-19 treatments. The company has alleged that Pfizer’s COVID...
Executive/Board ChangesShareholder Meetings
Enanta Shareholders Approve Board Elections and Equity Plan
Positive
Mar 12, 2026
At its annual meeting on March 11, 2026, Enanta Pharmaceuticals’ shareholders re-elected Bruce L.A. Carter, Ph.D., and Jay R. Luly, Ph.D., as Class I directors to serve until the 2029 annual meeting, reinforcing continuity in the company&#82...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 13, 2026