Financing And Commercial RunwayCompletion of a $57.5 million financing provides resources to continue development of tegoprubart and supports a commercially relevant opportunity given its noninferior efficacy and safety advantages.
Regulatory Pathway And DevelopmentCompany plans to seek regulatory agreement on trial design to advance tegoprubart into a Phase III kidney transplantation study, which could accelerate development if regulators accept the proposed design and data package.
Safety ProfileClinical results reported no biopsy-proven acute rejection or graft loss and indicated fewer opportunistic infections along with lower rates of metabolic, neurologic, and cardiovascular toxicities compared with current standard care, supporting a differentiated safety profile.