Kidney Function OutcomesTegoprubart produced among the highest mean kidney function levels reported in transplant trials, suggesting a potential advantage in preserving graft performance relative to current therapies.
Regulatory PathwayCompany plans to pursue a Phase III kidney transplantation program following regulatory discussions, which could accelerate development and provide clearer approval and data requirements if agreed.
Safety ProfileClinical data show a differentiated safety profile for tegoprubart with fewer opportunistic infections and lower rates of metabolic, neurologic, and cardiovascular toxicities compared with standard care, which could attract clinicians focused on long-term patient health.