Commercial Product Launches and Expanded Partnerships
Multiple products moved into commercialization: recombinant human albumin (ProLyte) commercially launched in early 2026 via a profit-sharing partnership with ProLiant; recombinant RNase-free DNase I launched with Fermox under expanded partnership; first sales of fibroblast growth factor (FGF) in 2025; OEM distribution agreement with IVT BioServices to accelerate global sales and market penetration.
Meaningful Grant Funding and Near-Term Non-Dilutive Revenue
Grant revenue increased materially, driven by Gates Foundation and CEPI activity: an incremental $1,860,000 in grant revenue in 2025 and approximately $2,400,000 received to date from the Gates Foundation under a $3,100,000 grant, providing capital-efficient, non-dilutive support for development and operations.
Pipeline Advancement Across Life Sciences, Food & Nutrition, and Bioindustrial
Clear multiproduct pipeline progress: transferrin (bovine and human) advancing toward commercialization, stable production strain for human lactoferrin under optimization, recombinant bovine chymosin partnership with Incyte targeting a 2026 launch with upfront fees and milestones, and N3xi enzyme cocktail achieving first large-scale order through Fermox.
Platform and Technology Validation via Strategic Collaborations
C1/DAPIBUS platform validated across multiple partner-funded programs: C1-derived monoclonal antibodies for RSV and malaria comparable to CHO-produced material; pre-fusion RSV antigens comparable to mammalian production and potentially improved vs insect-cell systems; active collaborations with Gates, CEPI, NIAID, NIH, Scripps Research, Oxford, UVAX, and others that provide development funding and external validation.
Commercial and Manufacturing Leverage Through Partners
Strategy to de-risk scale-up: expanded Fermox partnership provides access to commercial-scale manufacturing and additional product development (profit-sharing model), while distribution partners (IVT, ProLiant) provide sales channels and application expertise—enabling commercialization without heavy capital spend.
Cash Position and Runway
Ending cash and equivalents approximately $8.6M with net cash used in operating activities of about $5.7M for 2025; management expects disciplined cash use and believes current resources provide a runway into 2027 while pursuing strategic partnerships and optional capital tools (ATM) for flexibility.