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Precision Biosciences (DTIL)
NASDAQ:DTIL

Precision BioSciences (DTIL) AI Stock Analysis

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DTIL

Precision BioSciences

(NASDAQ:DTIL)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$6.00
▲(3.09% Upside)
Action:ReiteratedDate:03/18/26
Overall score is held back primarily by weak financial performance (large losses, steep TTM revenue drop, and heavy cash burn). Technicals are constructive but overbought, while corporate updates and stated cash runway provide some support; valuation remains a headwind due to negative earnings and no dividend.
Positive Factors
Balance sheet strength
Very low reported debt relative to equity provides lasting financial flexibility for an early‑stage biotech. This reduces interest burden and leaves capital structure room to fund R&D or negotiate partnerships without immediate leverage constraints, supporting multi‑year program execution.
Negative Factors
High cash burn
Persistent, large negative operating and free cash flow materially increases financing dependency. Over months this trend erodes runway if not offset by milestone receipts or financing, raising dilution risk and potentially forcing reprioritization or slowing of clinical programs.
Read all positive and negative factors
Positive Factors
Negative Factors
Balance sheet strength
Very low reported debt relative to equity provides lasting financial flexibility for an early‑stage biotech. This reduces interest burden and leaves capital structure room to fund R&D or negotiate partnerships without immediate leverage constraints, supporting multi‑year program execution.
Read all positive factors

Precision BioSciences (DTIL) vs. SPDR S&P 500 ETF (SPY)

Precision BioSciences Business Overview & Revenue Model

Company Description
Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing and ex vivo allogeneic CAR T therapies in the United States. It offers ARCUS, a genome editing platform to cure genetic disorders. The company also p...
How the Company Makes Money
Precision BioSciences primarily generates revenue through collaboration and licensing arrangements tied to its ARCUS genome editing platform rather than through commercial product sales (as it is a clinical-stage company). Key revenue streams typi...

Precision BioSciences Financial Statement Overview

Summary
Financials are pressured by sharp TTM revenue decline and a return to large losses, alongside materially negative operating and free cash flow (significant cash burn). The main offset is a relatively supportive balance sheet with very low debt versus equity, but funding runway/execution remain key swing factors.
Income Statement
24
Negative
Balance Sheet
67
Positive
Cash Flow
18
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue34.26M68.70M48.73M25.10M115.53M
Gross Profit31.51M68.70M48.73M25.10M115.53M
EBITDA-49.40M13.53M-32.04M-62.79M-20.27M
Net Income-46.61M7.17M-61.32M-111.64M-30.60M
Balance Sheet
Total Assets154.42M136.39M159.78M238.17M211.50M
Cash, Cash Equivalents and Short-Term Investments115.58M86.31M116.68M189.58M143.66M
Total Debt28.81M30.05M31.27M24.96M9.11M
Total Liabilities62.17M80.00M140.92M177.74M120.33M
Stockholders Equity92.25M56.39M18.86M60.43M91.17M
Cash Flow
Free Cash Flow-65.93M-58.70M-86.39M-49.07M-16.66M
Operating Cash Flow-65.84M-58.45M-84.11M-45.75M-10.85M
Investing Cash Flow-634.00K-215.00K5.83M-3.32M-5.80M
Financing Cash Flow95.16M50.45M5.39M94.98M70.52M

Precision BioSciences Technical Analysis

Technical Analysis Sentiment
Positive
Last Price5.82
Price Trends
50DMA
4.80
Positive
100DMA
4.77
Positive
200DMA
5.02
Positive
Market Momentum
MACD
0.31
Positive
RSI
54.06
Neutral
STOCH
21.33
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DTIL, the sentiment is Positive. The current price of 5.82 is below the 20-day moving average (MA) of 5.95, above the 50-day MA of 4.80, and above the 200-day MA of 5.02, indicating a neutral trend. The MACD of 0.31 indicates Positive momentum. The RSI at 54.06 is Neutral, neither overbought nor oversold. The STOCH value of 21.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DTIL.

Precision BioSciences Risk Analysis

Precision BioSciences disclosed 73 risk factors in its most recent earnings report. Precision BioSciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Precision BioSciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$143.91M-1.14-96.96%-99.07%-10347.56%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$58.89M-1.19-53.71%21.17%
46
Neutral
$985.77M-6.84-19.77%-10.26%144.62%
45
Neutral
$67.08M-0.50-82.96%25.89%
41
Neutral
$55.59M-0.74-33.05%-100.00%45.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DTIL
Precision BioSciences
5.82
1.21
26.25%
CTMX
CytomX Therapeutics
4.56
4.10
902.20%
ACET
Adicet Bio
6.99
-3.23
-31.60%
IMA
ImageneBio
4.97
-8.59
-63.35%
ACRV
Acrivon Therapeutics, Inc.
1.52
0.01
0.66%

Precision BioSciences Corporate Events

Business Operations and StrategyProduct-Related Announcements
Precision BioSciences Highlights PBGENE-DMD Program and Trial
Positive
Mar 17, 2026
On March 17, 2026, Precision BioSciences hosted a live investor and key opinion leader webcast to provide an update on its PBGENE-DMD gene-editing program and the FUNCTION-DMD Phase 1/2 trial for Duchenne muscular dystrophy. Pediatric neurologist ...
Business Operations and StrategyFinancial Disclosures
Precision BioSciences Highlights 2026 Gene Editing Priorities
Positive
Jan 13, 2026
On January 12, 2026, Precision BioSciences outlined its 2026 strategic priorities centered on advancing its two lead ARCUS-based in vivo gene editing programs—PBGENE-HBV for chronic hepatitis B and PBGENE-DMD for Duchenne muscular dystrophy&...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 18, 2026