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Precision Biosciences (DTIL)
NASDAQ:DTIL
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Precision BioSciences (DTIL) AI Stock Analysis

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DTIL

Precision BioSciences

(NASDAQ:DTIL)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$8.00
▲(1.52% Upside)
Action:Reiterated
Date:05/09/26
The score is held back primarily by persistent losses and ongoing negative operating/free cash flow, which elevate financing risk. Offsetting this, technical indicators show improving momentum with the stock trading above key moving averages and a positive MACD. Valuation is constrained by negative earnings (negative P/E), while the recent positive PBGENE-DMD program update provides some incremental support.
Positive Factors
Clinical-stage ARCUS platform progress
Progressing PBGENE-DMD into active patient screening and dosing readiness demonstrates the ARCUS platform is moving from preclinical to clinical validation. Achieving IND/CTA milestones and trial activation builds durable technical credibility and de-risks future partner interest and regulatory engagement.
Negative Factors
Persistent negative cash generation
Sustained negative operating and free cash flows indicate the business burns cash to fund development, creating ongoing financing needs. Over the medium term this elevates dilution and refinancing risk, which can constrain strategic choices and slow program timelines if capital access tightens.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical-stage ARCUS platform progress
Progressing PBGENE-DMD into active patient screening and dosing readiness demonstrates the ARCUS platform is moving from preclinical to clinical validation. Achieving IND/CTA milestones and trial activation builds durable technical credibility and de-risks future partner interest and regulatory engagement.
Read all positive factors

Precision BioSciences (DTIL) vs. SPDR S&P 500 ETF (SPY)

Precision BioSciences Business Overview & Revenue Model

Company Description
Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing and ex vivo allogeneic CAR T therapies in the United States. It offers ARCUS, a genome editing platform to cure genetic disorders. The company also p...
How the Company Makes Money
Precision BioSciences primarily generates revenue through collaboration and licensing arrangements tied to its ARCUS genome editing platform rather than through commercial product sales (as it is a clinical-stage company). Key revenue streams typi...

Precision BioSciences Financial Statement Overview

Summary
Overall financial quality is below average. Income statement profitability is unstable with deeply negative operating and net margins in 2026 TTM, and cash flow is a key weakness with consistently negative operating cash flow and worsening free cash flow (continued cash burn). The balance sheet is comparatively better with manageable leverage and positive equity, but equity decline and sharply negative ROE reflect ongoing losses and financing risk.
Income Statement
34
Negative
Balance Sheet
56
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue45.07M34.26M68.70M48.73M25.10M115.53M
Gross Profit43.70M31.51M68.70M48.73M25.10M115.53M
EBITDA-31.36M-49.40M13.53M-32.04M-62.79M-20.27M
Net Income-44.48M-46.61M7.17M-61.32M-111.64M-30.60M
Balance Sheet
Total Assets143.89M154.42M136.39M159.78M238.17M211.50M
Cash, Cash Equivalents and Short-Term Investments101.18M115.58M86.31M116.68M189.58M143.66M
Total Debt28.47M28.81M30.05M31.27M24.96M9.11M
Total Liabilities67.79M62.17M80.00M140.92M177.74M120.33M
Stockholders Equity76.10M92.25M56.39M18.86M60.43M91.17M
Cash Flow
Free Cash Flow-58.78M-65.93M-58.70M-86.39M-49.07M-16.66M
Operating Cash Flow-58.73M-65.84M-58.45M-84.11M-45.75M-10.85M
Investing Cash Flow-434.00K-634.00K-215.00K5.83M-3.32M-5.80M
Financing Cash Flow85.22M95.16M50.45M5.39M94.98M70.52M

Precision BioSciences Technical Analysis

Technical Analysis Sentiment
Positive
Last Price7.88
Price Trends
50DMA
6.86
Positive
100DMA
5.47
Positive
200DMA
5.44
Positive
Market Momentum
MACD
0.18
Positive
RSI
44.42
Neutral
STOCH
19.41
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DTIL, the sentiment is Positive. The current price of 7.88 is above the 20-day moving average (MA) of 7.46, above the 50-day MA of 6.86, and above the 200-day MA of 5.44, indicating a neutral trend. The MACD of 0.18 indicates Positive momentum. The RSI at 44.42 is Neutral, neither overbought nor oversold. The STOCH value of 19.41 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DTIL.

Precision BioSciences Risk Analysis

Precision BioSciences disclosed 75 risk factors in its most recent earnings report. Precision BioSciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Precision BioSciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$761.96M-11.41-36.61%-75.91%-173.33%
52
Neutral
$179.58M-0.96-81.24%-11.87%-86.91%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$70.62M-0.71-64.43%9.80%
48
Neutral
$63.20M-1.32-35.20%49.30%
47
Neutral
$70.11M-0.90-80.35%27.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DTIL
Precision BioSciences
6.90
2.25
48.39%
CTMX
CytomX Therapeutics
3.64
1.60
78.43%
ACET
Adicet Bio
7.25
-3.95
-35.27%
IMA
ImageneBio
5.25
-8.55
-61.96%
ACRV
Acrivon Therapeutics, Inc.
1.60
0.45
39.13%

Precision BioSciences Corporate Events

Business Operations and StrategyProduct-Related Announcements
Precision BioSciences Highlights PBGENE-DMD Program and Trial
Positive
Mar 17, 2026
On March 17, 2026, Precision BioSciences hosted a live investor and key opinion leader webcast to provide an update on its PBGENE-DMD gene-editing program and the FUNCTION-DMD Phase 1/2 trial for Duchenne muscular dystrophy. Pediatric neurologist ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 09, 2026