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Precision Biosciences (DTIL)
NASDAQ:DTIL
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Precision BioSciences (DTIL) AI Stock Analysis

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DTIL

Precision BioSciences

(NASDAQ:DTIL)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$9.00
▲(14.21% Upside)
Action:Reiterated
Date:07/08/26
DTIL’s score is held back primarily by weak financial performance, driven by persistent losses and ongoing negative free cash flow (cash burn) despite some revenue improvement and a more manageable leverage profile. Technicals are supportive with a clear uptrend and positive MACD, but overbought readings elevate near-term risk. Corporate events add a modest positive tilt due to encouraging clinical progress and improved debt maturity profile, while valuation remains constrained by continued losses and a negative P/E.
Positive Factors
Proprietary Platform & Partner Model
Owning the ARCUS genome editing platform provides a durable technological moat and enables non-dilutive collaboration/licensing revenue streams. Long-term partnerships spread R&D cost, accelerate development via external resources, and reduce sole reliance on internal commercialization.
Negative Factors
Persistent Cash Burn
Continued negative operating and free cash flow indicates the company requires external capital or milestone/licensing receipts to sustain operations. Over a 2–6 month horizon this raises dilution or refinancing risk and limits discretionary spending on pipeline expansion.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary Platform & Partner Model
Owning the ARCUS genome editing platform provides a durable technological moat and enables non-dilutive collaboration/licensing revenue streams. Long-term partnerships spread R&D cost, accelerate development via external resources, and reduce sole reliance on internal commercialization.
Read all positive factors

Precision BioSciences (DTIL) vs. SPDR S&P 500 ETF (SPY)

Precision BioSciences Business Overview & Revenue Model

Company Description
Precision BioSciences, Inc. is a clinical-stage biotechnology firm based in the United States, specializing in the creation of both in vivo gene editing solutions and ex vivo allogeneic CAR T-cell therapies. At its core is ARCUS, a proprietary gen...
How the Company Makes Money
Precision BioSciences generates revenue primarily through collaboration and licensing arrangements tied to its ARCUS genome editing platform rather than from product sales (as it has been a clinical-stage company). These arrangements typically inc...

Precision BioSciences Financial Statement Overview

Summary
Overall financial quality is below average. Income statement profitability is unstable with deeply negative operating and net margins in 2026 TTM despite a revenue rebound, and cash flow is a major weakness with consistently negative operating cash flow and free cash flow (continued cash burn). The balance sheet is comparatively better with manageable leverage and positive equity, but equity has been declining and ROE is sharply negative due to ongoing losses.
Income Statement
34
Negative
Balance Sheet
56
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue45.07M34.26M68.70M48.73M25.10M115.53M
Gross Profit45.07M34.26M68.70M48.73M25.10M115.53M
EBITDA-40.42M-42.43M13.53M-32.04M-62.79M-20.27M
Net Income-43.60M-45.72M7.17M-61.32M-111.64M-30.60M
Balance Sheet
Total Assets143.89M154.42M136.39M159.78M238.17M211.50M
Cash, Cash Equivalents and Short-Term Investments101.18M115.58M86.31M116.68M189.58M143.66M
Total Debt28.47M28.81M30.05M31.27M24.96M9.11M
Total Liabilities67.79M62.17M80.00M140.92M177.74M120.33M
Stockholders Equity76.10M92.25M56.39M18.86M60.43M91.17M
Cash Flow
Free Cash Flow-58.78M-65.93M-58.70M-86.39M-49.07M-16.66M
Operating Cash Flow-58.73M-65.84M-58.45M-84.11M-45.75M-10.85M
Investing Cash Flow-434.00K-634.00K-215.00K5.83M-3.32M-5.80M
Financing Cash Flow85.22M95.16M50.45M5.39M94.98M70.52M

Precision BioSciences Technical Analysis

Technical Analysis Sentiment
Positive
Last Price7.88
Price Trends
50DMA
7.30
Positive
100DMA
6.58
Positive
200DMA
5.86
Positive
Market Momentum
MACD
0.57
Negative
RSI
65.94
Neutral
STOCH
79.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DTIL, the sentiment is Positive. The current price of 7.88 is above the 20-day moving average (MA) of 7.47, above the 50-day MA of 7.30, and above the 200-day MA of 5.86, indicating a bullish trend. The MACD of 0.57 indicates Negative momentum. The RSI at 65.94 is Neutral, neither overbought nor oversold. The STOCH value of 79.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DTIL.

Precision BioSciences Risk Analysis

Precision BioSciences disclosed 75 risk factors in its most recent earnings report. Precision BioSciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Precision BioSciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$69.80M-1.27-35.20%49.30%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$818.56M-36.61%-75.91%-173.33%
49
Neutral
$226.03M-81.24%-11.87%-86.91%
48
Neutral
$83.89M-0.97-64.43%9.80%
47
Neutral
$82.54M-0.59-80.35%27.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DTIL
Precision BioSciences
8.76
4.12
88.79%
CTMX
CytomX Therapeutics
3.76
1.37
57.32%
ACET
Adicet Bio
8.83
-3.63
-29.12%
IMA
ImageneBio
5.91
-10.53
-64.05%
ACRV
Acrivon Therapeutics, Inc.
1.96
0.63
47.37%

Precision BioSciences Corporate Events

Business Operations and StrategyProduct-Related Announcements
Precision BioSciences Advances Gene-Editing Programs in Hepatitis B
Positive
Jul 1, 2026
Precision BioSciences, Inc. is a biotechnology company focused on developing gene-editing therapies targeting serious chronic and genetic diseases. Its pipeline includes programs for chronic hepatitis B and Duchenne muscular dystrophy, positioning...
Business Operations and StrategyPrivate Placements and Financing
Precision BioSciences Extends Term Loan Maturity to 2029
Positive
Jun 16, 2026
On June 10, 2026, Precision BioSciences, Inc. amended its existing loan and security agreement with Banc of California, entering into a first amendment that modifies the terms of its term loan facility. Under the revised agreement, the maturity da...
Business Operations and StrategyProduct-Related Announcements
Precision BioSciences Reports Promising New Hepatitis B Trial Data
Positive
May 27, 2026
On May 27, 2026, Precision BioSciences reported new and late-breaking clinical and biopsy data from its ongoing Phase 1 ELIMINATE-B trial of PBGENE-HBV in chronic hepatitis B, presented at the European Association for the Study of the Liver Congre...
Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and ComplianceShareholder Meetings
Precision BioSciences Shareholders Approve Incentive Plan and Directors
Positive
May 26, 2026
On May 21, 2026, Precision BioSciences held its annual meeting of stockholders, where shareholders approved an amended and restated 2019 Incentive Award Plan that increases the pool of shares available for equity-based compensation by 3,800,000 sh...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 08, 2026