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Silence Therapeutics (DE:XRP2)
FRANKFURT:XRP2
XRP2 Stock Chart & Stats
€4.92
-€0.85(-11.89%)
At close: 4:00 PM EST
€4.92
-€0.85(-11.89%)
Day’s Range― - ―
52-Week Range€1.70 - €7.50
Previous CloseN/A
Volume0.00
Average Volume (3M)78.00
Market Cap
€247.64M
Enterprise Value€143.13M
Total Cash (Recent Filing)€102.19M
Total Debt (Recent Filing)€182.00K
Price to Earnings (P/E)―
Beta1.33
Next Earnings
Mar 18, 2026EPS Estimate
-0.17Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-0.13
Shares Outstanding47,233,948
10 Day Avg. Volume87
30 Day Avg. Volume78
Financial Highlights & Ratios
PEG Ratio0.47
Price to Book (P/B)2.42
Price to Sales (P/S)7.51
P/FCF Ratio-4.79
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price Target
€63.76Price Target Upside1195.98% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering2
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
Bulls Say, Bears Say
Bulls Say
Clinical Trials And InnovationManagement underscored continued progress in Silence’s early-stage pipeline, including advancement of the AstraZeneca-partnered SLN312 program in Phase 1 and promising extra-hepatic delivery research expanding beyond hepatic targets.
Pipeline And PartnershipsNear-term catalysts include the potential announcement of a zerlasiran partnership, updates from ongoing AstraZeneca collaboration activities, and continued preclinical readouts from the company’s extra-hepatic platform—all of which support meaningful upside toward the target.
Regulatory EnvironmentSilence Therapeutics stands to benefit from the FDA’s draft guidances, which underscore the agency’s broader acceptance of flexible trial designs and real-world evidence as key components of modern regulatory science.
Bears Say
Clinical Development RisksRisks include clinical development risk tied to zerlasiran and divesiran, among other development candidates.
Commercialization And Market RisksThere is a risk associated with commercialization, including reimbursement and pricing challenges.
Competitor And Novelty RisksCompetitor risk and novel modality risk pose challenges to the future success of Silence's development candidates.
Silence Therapeutics News
XRP2 FAQ
What was Silence Therapeutics’s price range in the past 12 months?
Silence Therapeutics lowest stock price was €1.70 and its highest was €7.50 in the past 12 months.
What is Silence Therapeutics’s market cap?
Silence Therapeutics’s market cap is €247.64M.
When is Silence Therapeutics’s upcoming earnings report date?
Silence Therapeutics’s upcoming earnings report date is Mar 18, 2026 which is in 72 days.
How were Silence Therapeutics’s earnings last quarter?
Silence Therapeutics released its earnings results on Nov 06, 2025. The company reported -€0.128 earnings per share for the quarter, beating the consensus estimate of -€0.159 by €0.032.
Is Silence Therapeutics overvalued?
According to Wall Street analysts Silence Therapeutics’s price is currently Undervalued.
Does Silence Therapeutics pay dividends?
Silence Therapeutics does not currently pay dividends.
What is Silence Therapeutics’s EPS estimate?
Silence Therapeutics’s EPS estimate is -0.17.
How many shares outstanding does Silence Therapeutics have?
Silence Therapeutics has 47,233,948 shares outstanding.
What happened to Silence Therapeutics’s price movement after its last earnings report?
Silence Therapeutics reported an EPS of -€0.128 in its last earnings report, beating expectations of -€0.159. Following the earnings report the stock price went down -4.63%.
Which hedge fund is a major shareholder of Silence Therapeutics?
Currently, no hedge funds are holding shares in DE:XRP2
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Silence Therapeutics Stock Smart Score
Neutral
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Technicals
SMA
Positive
20 days / 200 days
Momentum
-10.12%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
-35.39%
Trailing 12-Months
Company Description
Silence Therapeutics
Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA molecules to harness the body's natural mechanism of RNA interference, and degrading messenger RNA molecules that encode specific targeted disease-associated proteins in a cell. The company is developing various product candidates, including SLN360, which is Phase I clinical trials for the treatment of cardiovascular disease with high lipoprotein; SLN124 that is in Phase I clinical trials for the treatment of non-transfusion dependent thalassemia, and Phase I clinical trials for the treatment of myelodysplastic syndrome; and SLN124 for the treatment of polycythemia vera. It has collaboration agreements with AstraZeneca PLC to discover, develop, and commercialize small interfering RNA therapeutics for the treatment of cardiovascular, renal, metabolic, and respiratory diseases; and Mallinckrodt Pharma IP Trading DAC to develop and commercialize RNAi drug targets designed to silence the complement cascade in complement-mediated disorders. The company also has a collaboration with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three undisclosed targets leveraging Silence's mRNAi GOLD platform. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc is headquartered in London, the United Kingdom.
XRP2 Stock 12 Month Forecast
Average Price Target
€63.76
▲(1195.98% Upside)
Technical Analysis
Options Prices
Currently, No data available
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