Commercial OpportunityThe lead program KRRO-110 aims to treat AATD and presents a significant commercial opportunity due to high unmet need and lack of approved disease-modifying therapies.
RNA Editing PotentialRNA editing holds significant potential based on preclinical data and Korro is one of the leaders in the field.
Safety And EfficacyKRRO-110 dosing was safely completed in ~5 SAD HV cohorts, further derisking KRRO-110 LNP safety, given that the assessed doses are likely therapeutically active in AATD patients.