Clinical ProgressKRRO-110 dosing was safely completed in ~5 SAD HV cohorts, further derisking KRRO-110 LNP safety, given that the assessed doses are likely therapeutically active in AATD patients.
Commercial OpportunityThe lead program KRRO-110 aims to treat AATD and presents a significant commercial opportunity due to high unmet need and lack of approved disease-modifying therapies.
Regulatory MilestoneKRRO-110 has also received orphan drug designation from the EMA.