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Heidelberg Pharma AG (DE:HPHA)
XETRA:HPHA

Heidelberg Pharma AG (HPHA) AI Stock Analysis

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DE:HPHA

Heidelberg Pharma AG

(XETRA:HPHA)

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Underperform 39 (OpenAI - 4o)
Rating:39Underperform
Price Target:
€3.00
▲(23.97% Upside)
Heidelberg Pharma AG's overall stock score is heavily impacted by its poor financial performance, with significant losses and liquidity concerns. Technical analysis indicates bearish momentum, and valuation metrics are unattractive. These factors combine to result in a low overall score.
Positive Factors
Innovative Technology
Heidelberg Pharma's ATAC technology offers a competitive edge by enabling targeted cancer therapies, potentially improving treatment efficacy and reducing side effects, which can drive long-term growth through successful drug development and partnerships.
Partnership Revenue Model
The partnership-based revenue model provides a diversified income stream through upfront and milestone payments, reducing financial risk and supporting sustainable growth as drug candidates progress through clinical trials.
Low Leverage
Low leverage enhances financial stability, providing flexibility to invest in R&D and withstand market volatility, which is crucial for a biotech firm focused on long-term drug development.
Negative Factors
Declining Revenue
Significant revenue decline indicates challenges in commercializing products and sustaining operations, which could hinder future growth and investment in R&D if not addressed.
Negative Profitability
Persistent losses and negative profitability metrics suggest operational inefficiencies and financial strain, potentially limiting the company's ability to fund new projects and attract investment.
Cash Flow Challenges
Negative cash flow highlights liquidity issues, which may restrict the company's capacity to invest in growth opportunities and meet short-term obligations, impacting long-term sustainability.

Heidelberg Pharma AG (HPHA) vs. iShares MSCI Germany ETF (EWG)

Heidelberg Pharma AG Business Overview & Revenue Model

Company DescriptionHeidelberg Pharma AG, a biopharmaceutical company, focuses on oncology and antibody targeted amanitin conjugates (ATAC) in Germany, other European countries, the United States, and internationally. Its lead product candidate is HDP-101, which in the Phase I/IIa study for the treatment of relapsed or refractory multiple myeloma. It is developing HDP-102 for the treatment of non-Hodgkin lymphoma; HDP-103, an ATAC candidate to treat metastatic castration-resistant prostate cancer; HDP-104 for tumors; and HDP-XX for the treatment of solid/hematological tumors. The company is also developing MGTA-ATACs for HSCs, conditioning programs to treat blood cancers/genetic diseases; TAK-ATACs for oncology; and TLX250-CDx, a diagnostic antibody for imaging diagnostics of renal cancer in Phase III trials; urothelial carcinoma or bladder cancer in Phase I study; and triple-negative breast cancer in Phase II study. In addition, the company develops TLX250 (girentuximab), a therapeutic antibody, which is in Phase II study for patients with advanced clear cell renal cell carcinoma; RHB-107, an oral serine protease inhibitor that is in Phase II/III study to treat COVID-19, as well as for the treatment of advanced cholangiocarcinoma; and LH011 for pancreatic cancer. It has licensing agreement and strategic partnership with Huadong Medicine Co., Ltd. for the development and commercialization rights for HDP-101 and HDP-103 in Asia. The company was formerly known as Wilex AG and changed its name to Heidelberg Pharma AG in October 2017. Heidelberg Pharma AG was founded in 1997 and is based in Ladenburg, Germany.
How the Company Makes MoneyHeidelberg Pharma AG generates revenue primarily through the development and commercialization of its proprietary ADC technology. The company monetizes its research and development efforts by entering into strategic partnerships and collaborations with larger pharmaceutical companies, which provide funding and resources in exchange for rights to co-develop or license its therapies. Additionally, HPHA may receive milestone payments and royalties from these partnerships, contributing to its overall earnings. The company also seeks to secure grants and funding opportunities from public institutions or private investors focused on advancing cancer therapies, which further supports its financial model.

Heidelberg Pharma AG Financial Statement Overview

Summary
Heidelberg Pharma AG faces significant financial challenges, with declining revenues and substantial losses. Negative profit margins and return on equity reflect poor profitability. Despite low leverage indicating some financial stability, negative cash flows highlight liquidity concerns.
Income Statement
25
Negative
Heidelberg Pharma AG's income statement reveals significant challenges. The company has experienced a sharp decline in revenue, with a TTM revenue growth rate of -38.95%. Profitability metrics are concerning, with negative net profit margins and EBIT margins indicating substantial losses. Despite a strong gross profit margin of 76.91%, the company's high operating expenses are eroding profitability.
Balance Sheet
40
Negative
The balance sheet shows a relatively low debt-to-equity ratio of 0.0066, indicating low leverage, which is a positive aspect. However, the return on equity is significantly negative at -84.55%, reflecting poor profitability and potential challenges in generating returns for shareholders. The equity ratio is not provided, but the low leverage suggests some stability in capital structure.
Cash Flow
30
Negative
Cash flow analysis highlights negative operating cash flow and free cash flow, with a slight decrease in free cash flow growth. The operating cash flow to net income ratio is negative, indicating cash flow challenges. However, the free cash flow to net income ratio is slightly above 1, suggesting that free cash flow is slightly better aligned with net income despite the losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue4.18M6.85M9.86M18.51M1.75M8.49M
Gross Profit3.22M4.20M6.61M13.83M-2.96M2.89M
EBITDA-22.43M-18.37M-18.71M-16.19M-24.83M-17.55M
Net Income-23.31M-19.38M-20.35M-19.70M-26.63M-18.37M
Balance Sheet
Total Assets62.45M60.72M70.35M100.58M21.73M19.61M
Cash, Cash Equivalents and Short-Term Investments33.25M29.42M43.44M81.33M6.14M4.98M
Total Debt37.67M21.97M5.83M15.98M10.63M202.68K
Total Liabilities43.94M29.85M21.01M33.94M15.03M6.73M
Stockholders Equity18.52M30.87M49.34M66.64M6.70M12.88M
Cash Flow
Free Cash Flow-27.21M-30.04M-34.63M-9.48M-28.00M-19.33M
Operating Cash Flow-26.78M-29.59M-33.67M-8.86M-26.61M-17.89M
Investing Cash Flow-445.00K-449.13K5.85M-597.57K-1.40M-1.29M
Financing Cash Flow17.96M16.08M-10.05M84.00M29.17M14.29M

Heidelberg Pharma AG Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.42
Price Trends
50DMA
2.93
Negative
100DMA
3.32
Negative
200DMA
3.44
Negative
Market Momentum
MACD
-0.12
Positive
RSI
23.61
Positive
STOCH
18.94
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DE:HPHA, the sentiment is Negative. The current price of 2.42 is below the 20-day moving average (MA) of 2.79, below the 50-day MA of 2.93, and below the 200-day MA of 3.44, indicating a bearish trend. The MACD of -0.12 indicates Positive momentum. The RSI at 23.61 is Positive, neither overbought nor oversold. The STOCH value of 18.94 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for DE:HPHA.

Heidelberg Pharma AG Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
€345.35M15.514.18%9.27%65.65%
63
Neutral
€418.85M-2.47-34.48%-14.84%-338.52%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
€1.34B-58.47-18.82%-113.85%
48
Neutral
€57.46M-4.21-111.86%-4.90%-69.80%
39
Underperform
€113.22M-4.31-112.95%-64.15%-39.31%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DE:HPHA
Heidelberg Pharma AG
2.42
0.24
11.01%
DE:VSC
4SC AG
0.10
-3.71
-97.38%
DE:BIO
Biotest
36.20
-5.20
-12.56%
DE:BNN
B.R.A.I.N. Biotechnology Research and Information Network
2.63
-0.81
-23.55%
DE:ILM1
Medios AG
13.54
1.46
12.09%
DE:FYB
Formycon AG
23.70
-28.80
-54.86%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 26, 2025