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Cytokinetics (CYTK)
NASDAQ:CYTK
US Market

Cytokinetics (CYTK) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
Apr 30, 2026
After Close (Confirmed)
Period Ending
2026 (Q1)
Consensus EPS Forecast
-1.65
Last Year’s EPS
-1.36
Same Quarter Last Year
Based on 17 Analysts Ratings

Earnings Call Summary

Q4 2025
Earnings Call Date:Feb 24, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call emphasized material positive corporate milestones — regulatory approvals across major markets, immediate commercial readiness and early uptake indicators, large full-year revenue growth driven by collaboration milestones, and a strong cash balance — which collectively mark the company’s transition to a global commercial-stage biopharmaceutical company. Notwithstanding, costs have increased substantially as the company invests in commercial infrastructure and ongoing clinical programs, driving wider net losses and near-term uncertainty around product sales and ACACIA topline details. On balance, the strategic and operational positives (approvals, launch momentum, pipeline catalysts and strong cash runway) outweigh the financial short-term headwinds and information gaps, yielding a constructive but cautious outlook.
Company Guidance
Cytokinetics closed 2025 with ~$1.22B in cash, cash equivalents and investments (vs $1.25B at 2024 year‑end), including a $100M draw from Royalty Pharma (cash would have fallen ~$134M in 2025 excluding that draw); Q4 revenue was $17.8M (Q4’24 $16.9M) and FY revenue $88.0M (2024 $18.5M) — helped by a $52.4M technology transfer to Bayer and $15M in approval milestones — while Q4 R&D was $104.4M (Q4’24 $93.6M) and FY R&D $416.0M (2024 $339.4M), Q4 G&A $91.7M (Q4’24 $62.3M) and FY G&A $284.3M (2024 $215.3M), with net loss Q4 $183M ($1.50/sh) and FY net loss $785M ($6.54/sh) (2024 net loss $589.5M, $5.26/sh). For 2026 they will not give product‑sales guidance but expect GAAP combined R&D + SG&A of $830–$870M (including stock‑based comp $120–$130M; excluding SBC $700–$750M), will begin reporting product sales with Q1 2026 results, and will track three launch metrics (HCPs actively writing scripts, scripts per HCP, and patients on MYCorzo); commercial targets and milestones include >700 REMS‑certified HCPs within three weeks, >12,000 customer engagements, a goal of >50% CMI new‑patient preference share by 2026, Medicare access comparable to Camzyos in Q1 and commercial access comparable by Q4 2026, ACACIA‑HCM topline in Q2 2026, MYCorzo launch in Germany in Q2 2026, potential FDA sNDA decision on MAPLE‑HCM by Q4 2026, potential Health Canada approval in H2 2026, CEDAR adolescent cohort completion by Q4 2026, and continued execution of COMMUN‑HF, AMBER‑HFpEF and preclinical programs.
Regulatory Approvals and Global Commercial Transition
MYCorzo (aficamten) received FDA approval in the U.S., approval in China, a positive CHMP opinion and subsequent European Commission approval for the EU during the same week — enabling Cytokinetics' transition to a global commercial-stage company and planned first European launch in Germany in Q2 2026.
Early U.S. Commercial Launch Momentum
Commercial launch activities began immediately after FDA approval with REMS portal and patient support program live; first prescriptions dispensed within days and patients on therapy within the first week. Within three weeks, over 700 HCPs were REMS-certified and the company reported over 12,000 customer engagements, with Cardiovascular Account Specialists engaging over 95% of the 700 HCPs identified as high-prescribers.
Strong Full-Year Revenue Lift Driven by Collaborations and Milestones
Total revenues for full-year 2025 were $88.0M versus $18.5M in 2024, an increase of approximately +376%, primarily due to a $52.4M technology transfer to Bayer and $15.0M in approval-related milestones under the Sanofi license agreement.
Robust Cash Position Entering Commercial Phase
Year-end 2025 cash, cash equivalents and investments totaled approximately $1.22B (versus $1.25B at year-end 2024). The 2025 balance included a $100M drawing from the Royalty Pharma loan; excluding that draw, cash would have declined by about $134M during 2025.
Clinical Development Milestones and Trial Progress
Key near-term clinical milestones: topline results for ACACIA-HCM (non-obstructive HCM) expected in Q2 2026; sNDA for MAPLE-HCM submitted with FDA review expected by Q4 2026; Health Canada review accepted with potential approval later in 2026. Ongoing trials: COMMUN-HF has 100% U.S. site activation and >90% European site activation; AMBER-HFpEF cohort one enrollment expected complete Q1 2026.
Positive Clinical Data Narrative
MAPLE-HCM responder analyses showed significantly more patients on aficamten achieved positive responses vs metoprolol, with greater improvements in symptoms and cardiac biomarkers — results that have resonated in the cardiology community and support commercial messaging.
Launch Targets and Strategic Priorities
Company aims to achieve >50% of CMI new patient preference share by 2026, intends to grow the overall CMI category, and set capital allocation priorities on US launch, European readiness, label-expansion opportunities, and advancing pipeline programs.

Cytokinetics (CYTK) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

CYTK Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
Apr 30, 2026
2026 (Q1)
-1.65 / -
-1.36
Feb 24, 2026
2025 (Q4)
-1.56 / -1.50
-1.26-19.05% (-0.24)
Nov 05, 2025
2025 (Q3)
-1.57 / -2.55
-1.36-87.50% (-1.19)
Aug 07, 2025
2025 (Q2)
-1.43 / -1.12
-1.3114.50% (+0.19)
May 06, 2025
2025 (Q1)
-1.37 / -1.36
-1.33-2.26% (-0.03)
Feb 27, 2025
2024 (Q4)
-1.19 / -1.26
-1.388.70% (+0.12)
Nov 06, 2024
2024 (Q3)
-1.24 / -1.36
-1.35-0.74% (-0.01)
Aug 08, 2024
2024 (Q2)
-1.06 / -1.31
-1.342.24% (+0.03)
May 08, 2024
2024 (Q1)
-1.14 / -1.33
-1.383.62% (+0.05)
Feb 27, 2024
2023 (Q4)
-0.96 / -1.38
-1.454.83% (+0.07)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

CYTK Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Feb 24, 2026
$70.10$62.89-10.29%
Nov 05, 2025
$59.19$60.30+1.88%
Aug 07, 2025
$35.25$34.11-3.23%
May 06, 2025
$33.97$33.04-2.74%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Cytokinetics (CYTK) report earnings?
Cytokinetics (CYTK) is schdueled to report earning on Apr 30, 2026, After Close (Confirmed).
    What is Cytokinetics (CYTK) earnings time?
    Cytokinetics (CYTK) earnings time is at Apr 30, 2026, After Close (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is CYTK EPS forecast?
          CYTK EPS forecast for the fiscal quarter 2026 (Q1) is -1.65.