Strong Revenue and Test Volume Growth
Castle Biosciences reported revenue of $86.2 million with a total test report volume of 26,574, representing a 33% year-over-year growth for core revenue drivers compared to Q2 2024.
DecisionDx-Melanoma Test Success
The DecisionDx-Melanoma test saw a sequential increase of approximately 16% compared to Q1 2025 and a year-over-year increase of 4%. The test was associated with a 32% reduction in mortality risk in a real-world cohort.
Significant Growth in TissueCypher Test
TissueCypher test reports increased to 9,170 in Q2 2025 from 4,782 in Q2 2024, marking a 92% year-over-year growth.
Strong Financial Position
Castle ended the quarter with $275.9 million in cash, cash equivalents, and marketable securities, supporting continued investment in growth initiatives.
Raised Revenue Guidance
For total revenue in 2025, guidance was raised to $310 million to $320 million, up from the previous range of $287 million to $297 million.
Successful Collaborations and Pipeline Developments
Castle entered into a collaboration with SciBase and reported success in its internally developed atopic dermatitis test, expected to launch by the end of 2025.